메뉴 건너뛰기




Volumn 83, Issue 3, 2012, Pages 158-167

Postnatal growth defect in mice upon persistent Hoxa2 expression in the chondrogenic cell lineage

Author keywords

Chondrogenesis; Endochondral ossification; Hoxa2; Lordosis; Proportionate short stature

Indexed keywords

BETA ACTIN; COLLAGEN TYPE 2; COLLAGEN TYPE II A1; UNCLASSIFIED DRUG;

EID: 84857232728     PISSN: 03014681     EISSN: 14320436     Source Type: Journal    
DOI: 10.1016/j.diff.2011.10.001     Document Type: Article
Times cited : (1)

References (56)
  • 2
    • 0033917762 scopus 로고    scopus 로고
    • Targeted disruption of the homeobox transcription factor Bapx1 results in lethal skeletal dysplasia with asplenia and gastroduodenal malformation
    • Akazawa H., Komuro I., Sugitani Y., Yazaki Y., Nagai R., Noda T. Targeted disruption of the homeobox transcription factor Bapx1 results in lethal skeletal dysplasia with asplenia and gastroduodenal malformation. Genes to Cells 2000, 5:499-513.
    • (2000) Genes to Cells , vol.5 , pp. 499-513
    • Akazawa, H.1    Komuro, I.2    Sugitani, Y.3    Yazaki, Y.4    Nagai, R.5    Noda, T.6
  • 7
    • 53149110818 scopus 로고    scopus 로고
    • Localization of tartrate-resistant acid phosphatase (TRAP), membrane type-1 matrix metalloproteinases (MT1-MMP) and macrophages during early endochondral bone formation
    • Blumer M.J., Longato S., Fritsch H. Localization of tartrate-resistant acid phosphatase (TRAP), membrane type-1 matrix metalloproteinases (MT1-MMP) and macrophages during early endochondral bone formation. Journal of Anatomy 2008, 213:431-441.
    • (2008) Journal of Anatomy , vol.213 , pp. 431-441
    • Blumer, M.J.1    Longato, S.2    Fritsch, H.3
  • 8
    • 46849098011 scopus 로고    scopus 로고
    • Regulation of cartilage formation and maturation by mitogen-activated protein kinase signaling
    • Bobick B.E., Kulyk W.M. Regulation of cartilage formation and maturation by mitogen-activated protein kinase signaling. Birth Defects Research Part C: Embryo Today 2008, 84:131-154.
    • (2008) Birth Defects Research Part C: Embryo Today , vol.84 , pp. 131-154
    • Bobick, B.E.1    Kulyk, W.M.2
  • 10
    • 0030984753 scopus 로고    scopus 로고
    • Drying cells for SEM, AFM and TEM by hexamethyldisilazane: a study on hepatic endothelial cells
    • Braet F., De Zanger R., Wisse E. Drying cells for SEM, AFM and TEM by hexamethyldisilazane: a study on hepatic endothelial cells. Journal of Microscopy 1997, 186:84-87.
    • (1997) Journal of Microscopy , vol.186 , pp. 84-87
    • Braet, F.1    De Zanger, R.2    Wisse, E.3
  • 13
    • 0035263614 scopus 로고    scopus 로고
    • A Ser(365)→Cys mutation of fibroblast growth factor receptor 3 in mouse downregulates Ihh/PTHrP signals and causes severe achondroplasia
    • Chen L., Li C., Qiao W., Xu X., Deng C. A Ser(365)→Cys mutation of fibroblast growth factor receptor 3 in mouse downregulates Ihh/PTHrP signals and causes severe achondroplasia. Human Molecular Genetics 2001, 10:457-465.
    • (2001) Human Molecular Genetics , vol.10 , pp. 457-465
    • Chen, L.1    Li, C.2    Qiao, W.3    Xu, X.4    Deng, C.5
  • 14
    • 0000015641 scopus 로고
    • Outline for the study of scoliosis
    • Cobb J.R. Outline for the study of scoliosis. Instructional Course Lectures 1948, 5:261-275.
    • (1948) Instructional Course Lectures , vol.5 , pp. 261-275
    • Cobb, J.R.1
  • 17
    • 17844372752 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling in mesenchymal progenitors controls osteoblast and chondrocyte differentiation during vertebrate skeletogenesis
    • Day T.F., Guo X., Garrett-Beal L., Yang Y. Wnt/beta-catenin signaling in mesenchymal progenitors controls osteoblast and chondrocyte differentiation during vertebrate skeletogenesis. Developmental Cell 2005, 8:739-750.
    • (2005) Developmental Cell , vol.8 , pp. 739-750
    • Day, T.F.1    Guo, X.2    Garrett-Beal, L.3    Yang, Y.4
  • 23
    • 0036964935 scopus 로고    scopus 로고
    • Structural changes in the angiofollicular units between active and hypofunctioning follicles align with differences in the epithelial expression of newly discovered proteins involved in iodine transport and organification
    • Gerard A.C., Many M.C., Daumerie C., Costagliola S., Miot F., DeVijlder J.J., Colin I.M., Denef J.F. Structural changes in the angiofollicular units between active and hypofunctioning follicles align with differences in the epithelial expression of newly discovered proteins involved in iodine transport and organification. Journal of Clinical Endocrinology and Metabolism 2002, 87:1291-1299.
    • (2002) Journal of Clinical Endocrinology and Metabolism , vol.87 , pp. 1291-1299
    • Gerard, A.C.1    Many, M.C.2    Daumerie, C.3    Costagliola, S.4    Miot, F.5    DeVijlder, J.J.6    Colin, I.M.7    Denef, J.F.8
  • 24
    • 0343673829 scopus 로고    scopus 로고
    • Evidence for co-ordinated changes between vascular endothelial growth factor and nitric oxide synthase III immunoreactivity, the functional status of the thyroid follicles, and the microvascular bed during chronic stimulation by low iodine and propylthiouracyl in old mice
    • Gerard A.C., Xhenseval V., Colin I.M., Many M.C., Denef J.F. Evidence for co-ordinated changes between vascular endothelial growth factor and nitric oxide synthase III immunoreactivity, the functional status of the thyroid follicles, and the microvascular bed during chronic stimulation by low iodine and propylthiouracyl in old mice. European Journal of Endocrinology 2000, 142:651-660.
    • (2000) European Journal of Endocrinology , vol.142 , pp. 651-660
    • Gerard, A.C.1    Xhenseval, V.2    Colin, I.M.3    Many, M.C.4    Denef, J.F.5
  • 26
    • 0038291876 scopus 로고
    • Academic Press
    • Hall B.K. Cartilage 1983, vol 1. Academic Press.
    • (1983) Cartilage , vol.1
    • Hall, B.K.1
  • 27
    • 67749116061 scopus 로고    scopus 로고
    • Establishment of Hox vertebral identities in the embryonic spine precursors
    • Iimura T., Denans N., Pourquie O. Establishment of Hox vertebral identities in the embryonic spine precursors. Current Topics in Developmental Biology 2009, 88:201-234.
    • (2009) Current Topics in Developmental Biology , vol.88 , pp. 201-234
    • Iimura, T.1    Denans, N.2    Pourquie, O.3
  • 28
    • 0031858666 scopus 로고    scopus 로고
    • Hoxa-2 restricts the chondrogenic domain and inhibits bone formation during development of the branchial area
    • Kanzler B., Kuschert S.J., Liu Y.H., Mallo M. Hoxa-2 restricts the chondrogenic domain and inhibits bone formation during development of the branchial area. Development 1998, 125:2587-2597.
    • (1998) Development , vol.125 , pp. 2587-2597
    • Kanzler, B.1    Kuschert, S.J.2    Liu, Y.H.3    Mallo, M.4
  • 29
    • 0038688373 scopus 로고    scopus 로고
    • The complexities of skeletal biology
    • Karsenty G. The complexities of skeletal biology. Nature 2003, 423:316-318.
    • (2003) Nature , vol.423 , pp. 316-318
    • Karsenty, G.1
  • 30
    • 0036337353 scopus 로고    scopus 로고
    • Elevated transforming growth factor beta2 enhances apoptosis and contributes to abnormal outflow tract and aortic sac development in retinoic X receptor alpha knockout embryos
    • Kubalak S.W., Hutson D.R., Scott K.K., Shannon R.A. Elevated transforming growth factor beta2 enhances apoptosis and contributes to abnormal outflow tract and aortic sac development in retinoic X receptor alpha knockout embryos. Development 2002, 129:733-746.
    • (2002) Development , vol.129 , pp. 733-746
    • Kubalak, S.W.1    Hutson, D.R.2    Scott, K.K.3    Shannon, R.A.4
  • 31
    • 37249045392 scopus 로고    scopus 로고
    • Conditional expression of Wnt4 during chondrogenesis leads to dwarfism in mice
    • Lee H.H., Behringer R.R. Conditional expression of Wnt4 during chondrogenesis leads to dwarfism in mice. PLoS ONE 2007, 2:e450.
    • (2007) PLoS ONE , vol.2
    • Lee, H.H.1    Behringer, R.R.2
  • 33
    • 33750301324 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling interacts differentially with Ihh signaling in controlling endochondral bone and synovial joint formation
    • Mak K.K., Chen M.H., Day T.F., Chuang P.T., Yang Y. Wnt/beta-catenin signaling interacts differentially with Ihh signaling in controlling endochondral bone and synovial joint formation. Development 2006, 133:3695-3707.
    • (2006) Development , vol.133 , pp. 3695-3707
    • Mak, K.K.1    Chen, M.H.2    Day, T.F.3    Chuang, P.T.4    Yang, Y.5
  • 35
    • 42749092987 scopus 로고    scopus 로고
    • Transcription factors controlling osteoblastogenesis
    • Marie P.J. Transcription factors controlling osteoblastogenesis. Archives of Biochemistry and Biophysics 2008, 473:98-105.
    • (2008) Archives of Biochemistry and Biophysics , vol.473 , pp. 98-105
    • Marie, P.J.1
  • 37
    • 34547691668 scopus 로고    scopus 로고
    • Chondrocyte moves: clever strategies?
    • Morales T.I. Chondrocyte moves: clever strategies?. Osteoarthritis and Cartilage 2007, 15:861-871.
    • (2007) Osteoarthritis and Cartilage , vol.15 , pp. 861-871
    • Morales, T.I.1
  • 38
    • 0032413011 scopus 로고    scopus 로고
    • Repression of hedgehog signaling and BMP4 expression in growth plate cartilage by fibroblast growth factor receptor 3
    • Naski M.C., Colvin J.S., Coffin J.D., Ornitz D.M. Repression of hedgehog signaling and BMP4 expression in growth plate cartilage by fibroblast growth factor receptor 3. Development 1998, 125:4977-4988.
    • (1998) Development , vol.125 , pp. 4977-4988
    • Naski, M.C.1    Colvin, J.S.2    Coffin, J.D.3    Ornitz, D.M.4
  • 40
    • 12944265540 scopus 로고    scopus 로고
    • Col2a1-directed expression of Cre recombinase in differentiating chondrocytes in transgenic mice
    • Ovchinnikov D.A., Deng J.M., Ogunrinu G., Behringer R.R. Col2a1-directed expression of Cre recombinase in differentiating chondrocytes in transgenic mice. Genesis 2000, 26:145-146.
    • (2000) Genesis , vol.26 , pp. 145-146
    • Ovchinnikov, D.A.1    Deng, J.M.2    Ogunrinu, G.3    Behringer, R.R.4
  • 41
    • 1842613707 scopus 로고    scopus 로고
    • Atlas of Hox gene expression in the developing kidney
    • Patterson L.T., Potter S.S. Atlas of Hox gene expression in the developing kidney. Developmental Dynamics 2004, 229:771-779.
    • (2004) Developmental Dynamics , vol.229 , pp. 771-779
    • Patterson, L.T.1    Potter, S.S.2
  • 42
    • 69249100500 scopus 로고    scopus 로고
    • Human caspases: activation, specificity, and regulation
    • Pop C., Salvesen G.S. Human caspases: activation, specificity, and regulation. Journal of Biological Chemistry 2009, 284:21777-21781.
    • (2009) Journal of Biological Chemistry , vol.284 , pp. 21777-21781
    • Pop, C.1    Salvesen, G.S.2
  • 43
    • 84857232893 scopus 로고    scopus 로고
    • POSNA Achondroplasia
    • Available at: (accessed November 7.
    • POSNA Achondroplasia. Available at: (accessed November 7, 2010). http://wwwposnaorg/.
    • (2010)
  • 44
    • 84857232894 scopus 로고    scopus 로고
    • POSNA Short Stature
    • Available at: (accessed November 7.
    • POSNA Short Stature. Available at: (accessed November 7, 2010). http://wwwposnaorg/.
    • (2010)
  • 47
    • 0034068977 scopus 로고    scopus 로고
    • Physiological cell death of chondrocytes in vivo is not confined to apoptosis. New observations on the mammalian growth plate
    • Roach H.I., Clarke N.M. Physiological cell death of chondrocytes in vivo is not confined to apoptosis. New observations on the mammalian growth plate. Journal of Bone and Joint Surgery-British Volume 2000, 82:601-613.
    • (2000) Journal of Bone and Joint Surgery-British Volume , vol.82 , pp. 601-613
    • Roach, H.I.1    Clarke, N.M.2
  • 48
    • 0142215398 scopus 로고    scopus 로고
    • Cranial neural crest and the building of the vertebrate head
    • Santagati F., Rijli F.M. Cranial neural crest and the building of the vertebrate head. Nature Reviews: Neuroscience 2003, 4:806-818.
    • (2003) Nature Reviews: Neuroscience , vol.4 , pp. 806-818
    • Santagati, F.1    Rijli, F.M.2
  • 50
    • 77649339704 scopus 로고    scopus 로고
    • Expressing Hoxa2 across the entire endochondral skeleton alters the shape of the skeletal template in a spatially restricted fashion
    • Tavella S., Bobola N. Expressing Hoxa2 across the entire endochondral skeleton alters the shape of the skeletal template in a spatially restricted fashion. Differentiation 2010, 79:194-202.
    • (2010) Differentiation , vol.79 , pp. 194-202
    • Tavella, S.1    Bobola, N.2
  • 51
    • 52049116278 scopus 로고    scopus 로고
    • Caspases: determination of their activities in apoptotic cells
    • Vaculova A., Zhivotovsky B. Caspases: determination of their activities in apoptotic cells. Methods in Enzymology 2008, 442:157-181.
    • (2008) Methods in Enzymology , vol.442 , pp. 157-181
    • Vaculova, A.1    Zhivotovsky, B.2
  • 55
    • 34548830463 scopus 로고    scopus 로고
    • Hox patterning of the vertebrate axial skeleton
    • Wellik D.M. Hox patterning of the vertebrate axial skeleton. Developmental Dynamics 2007, 236:2454-2463.
    • (2007) Developmental Dynamics , vol.236 , pp. 2454-2463
    • Wellik, D.M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.