The desmin coil 1B mutation K190A impairs nebulin Z-disc assembly and destabilizes actin thin filaments

Journal of Cell Science

Volumn 124, Issue 20, 2011, Pages 3464-3476

  Conover, Gloria M ^a,b   Gregorio, Carol C ^a  

^a UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

^b TEXAS A AND M UNIVERSITY   (United States)

Author keywords

Actin thin filament; Desmin; Intermediate filaments; Nebulin; Z disc

Indexed keywords

CRYSTALLIN; DESMIN; MUTANT PROTEIN; NEBULIN; MUSCLE PROTEIN; PEPTIDE FRAGMENT;

ACTIN FILAMENT; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CARBOXY TERMINAL SEQUENCE; CHICK; CONTROLLED STUDY; GENE EXPRESSION; GENE MUTATION; IMMUNOFLUORESCENCE MICROSCOPY; MOLECULAR STABILITY; MUSCLE CELL; MUSCLE CONTRACTION; MUSCLE FIBER CULTURE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN BINDING; PROTEIN INTERACTION; QUANTITATIVE ANALYSIS; SKELETAL MUSCLE; ANIMAL; BINDING SITE; CELL CULTURE; CHICK EMBRYO; GENETICS; METABOLISM; MOUSE; MUTATION; PATHOLOGY; SARCOMERE; SITE DIRECTED MUTAGENESIS;

ACTIN CYTOSKELETON; ANIMALS; BINDING SITES; CELLS, CULTURED; CHICK EMBRYO; DESMIN; MICE; MUSCLE CELLS; MUSCLE PROTEINS; MUSCLE, SKELETAL; MUTAGENESIS, SITE-DIRECTED; MUTATION; PEPTIDE FRAGMENTS; PROTEIN BINDING; SARCOMERES;

EID: 84857227036     PISSN: 00219533     EISSN: 14779137     Source Type: Journal    
DOI: 10.1242/jcs.087080     Document Type: Article

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