Characterization of nebulette and nebulin and emerging concepts of their roles for vertebrate Z-discs

Journal of Molecular Biology

Volumn 282, Issue 1, 1998, Pages 111-123

  Millevoi, Stefania ^a   Trombitas, Karoly ^b   Kolmerer, Bernhard ^a   Kostin, Sawa ^c   Schaper, Jutta ^c   Pelin, Katarina ^d   Granzier, Henk ^b   Labeit, Siegfried ^a  

^a EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

^b WASHINGTON STATE UNIVERSITY   (United States)

^c MAX PLANCK INSTITUTE FOR HEART AND LUNG RESEARCH   (Germany)

^d UNIVERSITY OF HELSINKI   (Finland)

Author keywords

Differential splicing; Muscle ultrastructure; Nebulin and nebulette; SH3 domain; Vertebrate Z discs

Indexed keywords

COMPLEMENTARY DNA; NEBULIN;

AMINO TERMINAL SEQUENCE; ANIMAL TISSUE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CHROMOSOME 10P; CHROMOSOME 2Q; DNA SEQUENCE; GENE MAPPING; HUMAN; HUMAN TISSUE; IMMUNOELECTRON MICROSCOPY; NONHUMAN; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; VERTEBRATE;

EID: 0032508463     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.1998.1999     Document Type: Article

References (36)

1. Chen, M.-J. G., Shih, C. L. & Wang, K. (1993). Nebulin as an actin zipper. J. Biol. Chem. 268, 20327-20334.
2. Cox, D. R. (1985). Mapping with radiation hybrids. Genome Digest, 4, 14-15.
3. Feinberg, A. P. & Vogelstein, B. (1983). A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. Anal. Biochem. 13, 6-13.
4. Gautel, M., Goulding, D., Bullard, B., Weber, K. & Fürst, D. O. (1996). The central Z-disk region of titin is assembled from a novel repeat in variable copy numbers. J. Cell Sci. 109, 2747-2754.
5. Gregorio, C. C., Trombitás, K., Centner, T., Kolmerer, B., Stier, G., Kunke, K., Suzuki, K., Obermayr, F., Herrmann, B., Granzier, H., Sorimachi, H. & Labeit, S. (1998). The N terminal of titin spans the Z-disc. Its interaction with a novel 19 kDa ligand (T-cap) is required for sarcomeric integrity. J. Cell Biol. In the press.
6. Holtzer, H., Hijikata, T., Lin, Z. X., Zhang, Z. Q., Holtzer, S., Protasi, F., Franzini-, Amstrong C. & Sweeney, H. L. (1997). Independent assembly of 1.6 μm long bipolar MHC filaments and I-Z-I bodies. Cell Struct. Funct. 22, 83-93.
7. Hu, D. H., Kimura, S. & Maruyama, K. (1986). Sodium dodecyl sulfate gel electrophoretic studies of connectin-like high molecular weight proteins of various types of vertebrate and invertebrate muscle. J. Biochem. (Tokyo), 99, 1485-1492.
8. Kolmerer, B., Olivieri, N., Herrmann, B. G. & Labeit, S. (1996). A systematic search of the data bases for sequences homologous to titin/connectin. Advan. Biophys. 33, 3-11.
9. Kruger, M., Wright, J. & Wang, K. (1991). Nebulin as a length regulator of thin filaments of vertebrate skeletal muscles: correlation of thin filament length, nebulin size, and epitope profile. J. Cell Biol. 115, 97-107.
10. Labeit, S. & Kolmerer, B. (1995). The complete primary structure of human nebulin and its correlation to muscle structure. J. Mol. Biol. 248, 308-315.
11. Labeit, S., Gibson, T., Lakey, A., Leonard, K., Zeviani, M., Knight, P., Wardale, J. & Trinick, J. (1991). Evidence that nebulin is a protein-ruler in muscle thin filaments. FEBS Letters, 282, 313-316.
12. Locker, R. H. & Wild, D. J. C. (1986). A comparative study of high molecular weight proteins in various types of muscle across the animal kingdom. J. Biochem. (Tokyo), 99, 1473-1484.
13. Luo, G., Zhang, J. Q., Nguyen, T.-P., Herrera, A. H., Paterson, B. & Horowits, R. (1997a). Complete cDNA sequence and tissue localization of N-RAP, a novel nebulin-related protein. Cell Motil. Cytoskel. 38, 75-90.
14. Luo, G., Leroy, E., Kozak, C. A., Polymeropoulos, M. H. & Horowits, R. (1997b). Mapping of the gene (NRAP) encoding N-RAP in the mouse and human genomes. Genomics, 45, 229-232.
15. MacDonald, R. J., Swift, G. H., Przybyla, A. E. & Chirgwin, J. M. (1987). Isolation of RNA using guanidinium salts. Methods Enzymol. 152, 219-226.
16. Moncman, C. L. & Wang, K. (1995). Nebulette: a 107 kD nebulin-like protein in cardiac muscle. Cell Motil. Cytoskel. 32, 205-225.
17. Pelin, K., Ridanpää, M., Donner, K., Wilton, S., Krishnarajah, J., Laing, N., Kolmerer, B., Millevoi, S., Labeit, S., Chapelle, A. & Wallgren-Pettersson, C. (1997). Refined localization of the genes for nebulin and titin genes on chromosome 2q allows the assignment of nebulin as a candiate gene for autosomal recessive nemaline myopathy. Eur. J. Human Genet. 5, 229-234.
18. Pfuhl, M., Winder, S. J. & Pastore, A. (1994). Nebulin, a helical actin binding protein. EMBO J. 13, 1782-1789.
19. Pfuhl, M., Winder, S. J., Castiglione, Morelli M. A., Labeit, S. & Pastore, A. (1996). Correlation between conformational and binding properties of nebulin repeats. J. Mol. Biol. 257, 367-384.
20. Politou, A. S., Millevoi, S., Gautel, M., Kolmerer, B. & Pastore, A. (1998). SH3 in muscles: solution structure of the SH3 domain from nebulin. J. Mol. Biol. 276, 189-202.
21. Saiki, R. K., Scharf, S. J., Faloona, F., Mullis, G. T. & Erlich, H. A. (1985). Enzymatic amplification of beta-globin genomic sequences and restriction site analysis for diagnosis of sickle cell anemia. Science, 230, 1350-1354.
22. Sanger, F., Nicklen, S. & Coulson, A. R. (1977). DNA sequencing with chain-terminating inhibitors. Proc. Natl Acad. Sci. USA, 74, 5463-5467.
23. Schreiber, V., Masson, R., Linares, J. L., Mattei, M.-G., Tomasetto, C. & Rio, M.-C. (1998). Chromosomal assignment and expression pattern of the murine Lasp-1 gene. Gene, 207, 171-175.
24. Schuuring, E., Verhoeven, E., Mooi, W. J. & Michalides, R. J. (1992). Identification and cloning of two over-expressed genes, U21B31/PRAD1 and EMS1, within the amplified chromosome 11q13 region in human carcinomas. Oncogene, 7, 355-361.
25. Sorimachi, H., Freiburg, A., Kolmerer, B., Ishiura, S., Stier, G., Gregorio, C. C., Labeit, D., Linke, W. A., Suzuki, S. & Labeit, S. (1997). Tissue-specific expression and α-actinin binding properties of the Z disc titin. Implications for the nature of vertebrate Z discs. J. Mol. Biol. 270, 688-695.
26. Squire, J. (1981). The structural Basis of Muscle Contraction, Plenum Press, New York.
27. Trinick, J. (1994). Titin and nebulin: protein rulers in muscle?. Trends Biochem. Sci. 19, 405-409.
28. Trombitás, K., Jin, J.-P. & Granzier, H. (1995). The mechanically active domain of titin in cardiac muscle. Circulation Res. 77, 856-861.
29. Trombitás, K., Greaser, M., Labeit, S., Jin, J.-P., Kellermayer, M., Helmes, M. & Granzier, H. (1998). Titin extensibility in situ: entropic elasticity of permanently folded and permanently unfolded molecular segment. J. Cell Biol. 140, 853-859.
30. Vigoreaux, J. O. (1994). The muscle Z band: lessons in stress management. J. Muscle Res. Cell Motil. 15, 237-255.
31. Wang, K. & Wright, J. (1988). Architecture of the sarcomere matrix of skeletal muscle: immunoelectron microscopic evidence that suggests a set of parallel inextensible nebulin filaments anchored at the Z line. J. Cell Biol. 107, 2199-2212.
32. Wang, K., Knipfer, M., Huang, Q. Q., van Heerden, A., Hsu, L. C., Gutierrez, G., Quian, X. L. & Stedman, H. (1996). Human skeletal muscle nebulin sequence encodes a blueprint for thin filament architecture. Sequence motifs and affinity profiles of tandem repeats and terminal SH3. J . Biol. Chem. 271, 4304-4314.
33. Wright, J., Huang, Q. Q. & Wang, K. (1993). Nebulin is a full-length template of actin filaments in the skeletal muscle sarcomere: an immunoelectron microscopic study of its orientation and span with site-specific monoclonal antibodies. J. Muscle Res. Cell Motil. 14, 476-483.
34. Wu, H., Reynolds, A. B., Kanner, S. B., Vines, R. R. & Parsons, J. T. (1991). Identification and characterization of a novel cytoskeleton-associated pp60src substrate. Mol. Cell. Biol. 11, 5113-5124.
35. Zhang, J. Q., Luo, G., Herrera, A. H., Paterson, B. & Horowits, R. (1996). cDNA cloning of mouse nebulin. Evidence that the nebulin-coding sequence is highly conserved among vertebrates. Eur. J. Biochem. 239, 835-841.
36. Zhukarev, V., Sanger, J. M., Sanger, J. W., Goldman, Y. E. & Shuman, H. (1997). Distribution and orientation of rhodamine-phalloidin bound to thin filaments in skeletal and cardiac myofibrils. Cell Motil. Cytoskel. 37, 363-377.