Pre-synaptic dopamine D 3 receptor mediates cocaine-induced structural plasticity in mesencephalic dopaminergic neurons via ERK and Akt pathways

Journal of Neurochemistry

Volumn 120, Issue 5, 2012, Pages 765-778

  Collo, Ginetta ^a   Bono, Federica ^a   Cavalleri, Laura ^a   Plebani, Laura ^a   Merlo Pich, Emilio ^b   Millan, Mark J ^c   Spano, Pier Franco ^a,d   Missale, Cristina ^a  

^a UNIVERSITY OF BRESCIA   (Italy)

^b GLAXOSMITHKLINE   (United States)

^c INSTITUT DE RECHERCHES INTERNATIONALES SERVIER   (France)

^d IRCCS SAN CAMILLO HOSPITAL   (Italy)

Author keywords

cocaine; dopamine receptor; mesencephalon; p Akt; p ERK; structural plasticity

Indexed keywords

DOPAMINE 3 RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE B;

ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL STRUCTURE; COCAINE DEPENDENCE; CONTROLLED STUDY; DOPAMINERGIC NERVE CELL; EMBRYO; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; FEMALE; IN VITRO STUDY; IN VIVO STUDY; MORPHOMETRICS; MOUSE; MOUSE EMBRYO; NERVE CELL CULTURE; NERVE CELL PLASTICITY; NEUROPATHOLOGY; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION;

ANALYSIS OF VARIANCE; ANIMALS; BRAIN-DERIVED NEUROTROPHIC FACTOR; CELLS, CULTURED; COCAINE; DOPAMINE; DOPAMINE AGENTS; DOPAMINE UPTAKE INHIBITORS; DOPAMINERGIC NEURONS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; EMBRYO, MAMMALIAN; ENZYME INHIBITORS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; MESENCEPHALON; MICE; MICE, KNOCKOUT; NEURONS; ONCOGENE PROTEIN V-AKT; PRESYNAPTIC TERMINALS; RECEPTORS, DOPAMINE D3; SIGNAL TRANSDUCTION; TRITIUM; TYROSINE 3-MONOOXYGENASE;

MUS;

EID: 84857194505     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2011.07618.x     Document Type: Article

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