Dopamine D3 receptor-preferring agonists increase dendrite arborization of mesencephalic dopaminergic neurons via extracellular signal-regulated kinase phosphorylation

European Journal of Neuroscience

Volumn 28, Issue 7, 2008, Pages 1231-1240

  Collo, Ginetta ^a   Zanetti, Silvia ^a   Missale, Cristina ^a   Spano, PierFranco ^a  

^a UNIVERSITY OF BRESCIA   (Italy)

Author keywords

7 OH DPAT; Amphetamine; Mouse; Neurite outgrowth; Quinpirole; SB 277011 A

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 [1 (3 DIMETHYLAMINOPROPYL) 3 INDOLYL] 3 (3 INDOLYL)MALEIMIDE; 2 DIPROPYLAMINO 7 HYDROXYTETRALIN; 2 MORPHOLINO 8 PHENYLCHROMONE; AMPHETAMINE; DOPAMINE 2 RECEPTOR; DOPAMINE 3 RECEPTOR; DOPAMINE 3 RECEPTOR STIMULATING AGENT; MITOGEN ACTIVATED PROTEIN KINASE; N [4 [2 (6 CYANO 1,2,3,4 TETRAHYDRO 2 ISOQUINOLINYL)ETHYL]CYCLOHEXYL] 4 QUINOLINECARBOXAMIDE; QUINPIROLE; SULPIRIDE; TYROSINE 3 MONOOXYGENASE;

ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL TISSUE; ARTICLE; ASTROCYTE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DENDRITE; DENDRITIC ARBORIZATION; DOPAMINE UPTAKE; DOPAMINERGIC NERVE CELL; DOPAMINERGIC TRANSMISSION; DRUG MECHANISM; EMBRYO; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; IMMUNOREACTIVITY; INCUBATION TIME; MESENCEPHALON; MOUSE; NERVE CELL CULTURE; NERVE CELL GROWTH; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

AMPHETAMINE; ANIMALS; CELL SHAPE; CELLS, CULTURED; DENDRITES; DOPAMINE; DOPAMINE AGONISTS; DOPAMINE ANTAGONISTS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; MESENCEPHALON; MICE; NERVE GROWTH FACTORS; NEUROGENESIS; QUINPIROLE; RECEPTORS, DOPAMINE D2; RECEPTORS, DOPAMINE D3; SUBSTANTIA NIGRA; TETRAHYDRONAPHTHALENES; TYROSINE 3-MONOOXYGENASE;

EID: 53149125151     PISSN: 0953816X     EISSN: 14609568     Source Type: Journal    
DOI: 10.1111/j.1460-9568.2008.06423.x     Document Type: Article

References (28)

1. Beom, S.R., Cheong, D., Torres, G., Caron, M.G. Kim, K.M. (2004) Comparative studies of molecular mechanisms of dopamine D2 and D3 receptors for the activation of extracellular signal-regulated kinase. J. Biol. Chem., 279, 28304 28314.
2. Bustos, G., Abarca, J., Campusano, J., Bustos, V., Noriega, V. Allaga, E. (2004) Functional interactions between somatodendritic dopamine release, glutamate receptors and brain-derived neurotrophic factor expression in mesencephalic structures of the brain. Brain Res. Rev., 47, 126 144.
3. Consales, C., Volpicelli, F., Greco, D., Leone, L., Colucci-D'Amato, L., Perrone-Capano, C. di Porzio, U. (2007) GDNF signaling in embryonic midbrain neurons in vitro. Brain Res., 1159, 28 39.
4. Cussac, D., Newman-Tancredi, A., Pasteau, V. Millan, M.J. (1999) Human dopamine D3 receptors mediate mitogen-activated protein kinase activation via a phosphatidylinositol 3-kinase and an atypical protein kinase C-dependent mechanism. Mol. Pharmacol., 56, 1025 1030.
5. Daly, S.A. Waddington, J.L. (1993) Behavioural effects of the putative D-3 dopamine receptor agonist 7-OH-DPAT in relation to other 'D-2-like' agonists. Neuropharmacology, 32, 509 510.
6. Davila, V., Yan, Z., Craciun, L.C., Logothetis, D. Sulzer, D. (2003) D3 dopamine autoreceptors do not activate G-protein-gated inwardly rectifying potassium channel currents in substantia nigra dopamine neurons. J. Neurosci., 23, 5693 5697.
7. Diaz, J., Pilon, C., Le Foll, B., Gros, C., Triller, A., Schwartz, J.-C. Sokoloff, P. (2000) Dopamine D3 receptors expressed by all mesencephalic dopamine neurons. J. Neurosci., 20, 8677 8684.
8. Du, F., Li, R., Huang, Y., Xuping, L. Le, W. (2005) Dopamine D3 receptor-preferring agonists induce neurotrophic effects on mesencephalic dopamine neurons. Eur. J. Neurosci., 22, 2422 2430.
9. Flores, C. Stewart, J. (2000) Changes in astrocytic basic fibroblast growth factor expression during and after prolonged exposure to escalating doses of amphetamine. Neuroscience, 98, 287 293.
10. Gao, H.M., Hong, J.S., Zhang, W. Liu, B. (2002) Distinct role for microglia in rotenone-induced degeneration of dopaminergic neurons. J. Neurosci., 22, 782 790.
11. Joyce, J.N. Millan, M.J. (2007) Dopamine D3 receptor antagonist for protection and repair in Parkinson's disease. Curr. Opin. Pharmacol., 7, 100 105.
12. Levesque, D., Diaz, J., Pilon, C., Martres, M.P., Giros, B., Souil, E., Schott, D., Morgat, J.L., Schwartz, J.C. Sokoloff, P. (1992) Identification, characterization, and localization of the dopamine D3 receptor in rat brain using 7-[3H]hydroxy-N,N-di-n-propyl-2-aminotetralin. Proc. Natl. Acad. Sci. U.S.A., 89, 8155 8159.
13. Missale, C., Nash, S.R., Robinson, S.W., Jaber, M. Caron, M.G. (1998) Dopamine receptors: from structure to function. Physiol. Rev., 78, 189 225.
14. Miyazaki, I., Asanuma, M., Diaz-Corrales, F., Miyoshi, K. Ogawa, N. (2004) Direct evidence for expression of dopamine receptors in astrocytes from basal ganglia. Brain Res., 1029, 120 123.
15. Mueller, D., Chapman, C.A. Stewart, J. (2006) Amphetamine induces dendritic growth in ventral tegmental area dopaminergic neurons in vivo via basic fibroblast grow factor. Neuroscience, 137, 727 735.
16. Park, Y.H., Kantor, L., Guptaroy, B., Zhang, M., Wang, K.K. Gnegy, M.E. (2003) Repeated amphetamine treatment induces neurite outgrowth and enhanced amphetamine-stimulated dopamine release in rat pheochromocytoma cells (PC12 cells) via a protein kinase C- and mitogen activated protein kinase-dependent mechanism. J. Neurochem., 87, 1546 1557.
17. Reavill, C., Taylor, S.G., Wood, M.D., Ashmeade, T., Austin, N.E., Avenell, K.Y., Boyfield, I., Branch, C.L., Cilia, J., Coldwell, M.C., Hadley, M.S., Hunter, A.J., Jeffrey, P., Jewitt, F., Johnson, C.N., Jones, D.N., Medhurst, A.D., Middlemiss, D.N., Nash, D.J., Riley, G.J., Routledge, C., Stemp, G., Thewlis, K.M., Trail, B., Vong, A.K. Hagan, J.J. (2000) Pharmacological actions of a novel, high-affinity, and selective human dopamine D(3) receptor antagonist, SB-277011-A-A. J. Pharmacol. Exp. Ther., 294, 1154 1165.
18. Robinson, T.E., Jurson, P.A. Bentgen, K.M. (1988) Persistent sensitization of dopamine neurotransmission in ventral striatum (nucleus accumbens) produced by prior experience with (+)-amphetamine: a microdialysis study in freely moving rats. Brain Res., 462, 211 222.
19. Rouge'-Pont, F., Abrous, D.N., Le Moal, M. Piazza, P.V. (1999) Release of endogenous dopamine in cultured mesencephalic neurons: influence of dopaminergic agonists and glucocorticoid antagonists. Eur. J. Neurosci., 11, 2343 2350.
20. Schmidt, U., Beyer, C., Oestreicher, A.B., Rejsert, I., Schilling, K. Pilgrim, C. (1996) Activation of dopaminergic D1 receptors promotes morphogenesis of developing striatal neurons. Neuroscience, 74, 453 460.
21. Sokoloff, P., Diaz, J., Le Foll, B., Guillin, O., Leriche, L., Bezard, E. Gross, C. (2006) The dopamine D3 receptor: a therapeutic target for the treatment of neuropsychiatric disorders. CNS Neurol. Disord. Drug Targets, 5, 25 43.
22. Studer, L. (1997) Culture of substantia nigra neurons. Current Protocols in Neuroscience. Wiley, New York, pp. 3.3.1 3.3.12.
23. Sulzer, D., Chen, T.K., Lau, Y.Y., Kristensen, H., Rayport, S. Ewing, A. (1995) Amphetamine redistributes dopamine from synaptic vesicles to the cytosol and promotes reverse transport, J. Neurosci., 15, 4102 4108.
24. Van Kampen, J.M. Eckman, C.B. (2006) Dopamine D3 receptor agonist delivery to a model of Parkinson's disease restores the nigrostriatal pathway and improves locomotor behavior. J. Neurosci., 26, 7272 7280.
25. Van Kampen, J.M. Robertson, H.A. (2005) A possible role for dopamine D3 receptor stimulation in the induction of neurogenesis in the adult rat substantia nigra. Neuroscience, 136, 381 386.
26. Van Kampen, J.M., Hagg, T. Robertson, H.A. (2004) Induction of neurogenesis in the adult rat subventricular zone and neostriatum following dopamine D3 receptor stimulation. Eur. J. Pharmacol., 19, 2377 2387.
27. Wang, C., Buck, D.C., Yang, R., Macey, T.A. Neve, K.A. (2005) Dopamine D2 receptor stimulation of mitogen-activated protein kinase mediated by cell type-dependent transactivation of receptor tyrosine kinase. J. Neurochem., 93, 899 909.
28. Whone, A.L., Watt, R.L., Stoessl, A.J., Davis, M., Reske, S., Nahmias, C., Lang, A.E., Rascol, O., Ribeiro, M.J., Remy, P., Poewe, W.H., Hauser, R.A. Brooks, D.J. (2003) Slower progression of Parkinson's disease with ropinerole versus levodopa: the REAL-PET study. Ann. Neurol., 54, 93 101.