Premetazoan Origin of the Hippo Signaling Pathway

Cell Reports

Volumn 1, Issue 1, 2012, Pages 13-20

  Sebe Pedrs, Arnau ^a   Zheng, Yonggang ^b   Ruiz Trillo, Iñaki ^a,c   Pan, Duojia ^b,d  

^a INSTITUTE OF EVOLUTIONARY BIOLOGY CSIC UNIVERSITAT POMPEU FABRA   (Spain)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF BARCELONA   (Spain)

^d HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HIPPO PROTEIN; PHOSPHOTRANSFERASE; SCALLOPED PROTEIN; TRANSCRIPTION FACTOR; TRANSFERASE; UNCLASSIFIED DRUG; WART PROTEIN; YORKIE PROTEIN;

AMOEBA (GENUS); ARTICLE; CAPSASPORA OWCZARZAKI; CELL LINEAGE; CONTROLLED STUDY; DEVELOPMENTAL BIOLOGY; DROSOPHILA MELANOGASTER; GENE EXPRESSION REGULATION; GENE SEQUENCE; GENE TARGETING; GENOME ANALYSIS; MOLECULAR EVOLUTION; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; TISSUE GROWTH;

AMINO ACID SEQUENCE; AMOEBA; ANIMALS; DROSOPHILA MELANOGASTER; EVOLUTION, MOLECULAR; GENE EXPRESSION REGULATION; GENOMICS; LIKELIHOOD FUNCTIONS; MOLECULAR SEQUENCE DATA; PROTEIN-SERINE-THREONINE KINASES; SEQUENCE ALIGNMENT; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS;

ANIMALIA; CAPSASPORA OWCZARZAKI; DROSOPHILA MELANOGASTER; METAZOA;

EID: 84857129984     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2011.11.004     Document Type: Article

References (34)

1. Adamska M., Matus D.Q., Adamski M., Green K., Rokhsar D.S., Martindale M.Q., Degnan B.M. The evolutionary origin of hedgehog proteins. Curr. Biol. 2007, 17:R836-R837.
2. Badouel C., Garg A., McNeill H. Herding Hippos: regulating growth in flies and man. Curr. Opin. Cell Biol. 2009, 21:837-843.
3. Chen L., Chan S.W., Zhang X., Walsh M., Lim C.J., Hong W., Song H. Structural basis of YAP recognition by TEAD4 in the hippo pathway. Genes Dev. 2010, 24:290-300.
4. Dong J., Feldmann G., Huang J., Wu S., Zhang N., Comerford S.A., Gayyed M.F., Anders R.A., Maitra A., Pan D. Elucidation of a universal size-control mechanism in Drosophila and mammals. Cell 2007, 130:1120-1133.
5. Halder G., Johnson R.L. Hippo signaling: growth control and beyond. Development 2011, 138:9-22.
6. Harvey K., Tapon N. The Salvador-Warts-Hippo pathway - an emerging tumour-suppressor network. Nat. Rev. Cancer 2007, 7:182-191.
7. Hilman D., Gat U. The evolutionary history of YAP and the hippo/YAP pathway. Mol. Biol. Evol. 2011, 28:2403-2417.
8. Huang J., Wu S., Barrera J., Matthews K., Pan D. The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila Homolog of YAP. Cell 2005, 122:421-434.
9. Katoh K., Misawa K., Kuma K., Miyata T. MAFFT: a novel method for rapid multiple sequence alignment based on fast Fourier transform. Nucleic Acids Res. 2002, 30:3059-3066.
10. King N., Hittinger C.T., Carroll S.B. Evolution of key cell signaling and adhesion protein families predates animal origins. Science 2003, 301:361-363.
11. King N., Westbrook M.J., Young S.L., Kuo A., Abedin M., Chapman J., Fairclough S., Hellsten U., Isogai Y., Letunic I., et al. The genome of the choanoflagellate Monosiga brevicollis and the origin of metazoans. Nature 2008, 451:783-788.
12. Li Z., Zhao B., Wang P., Chen F., Dong Z., Yang H., Guan K.L., Xu Y. Structural insights into the YAP and TEAD complex. Genes Dev. 2010, 24:235-240.
13. Ling C., Zheng Y., Yin F., Yu J., Huang J., Hong Y., Wu S., Pan D. The apical transmembrane protein Crumbs functions as a tumor suppressor that regulates Hippo signaling by binding to Expanded. Proc. Natl. Acad. Sci. USA 2010, 107:10532-10537.
14. Maitra S., Kulikauskas R.M., Gavilan H., Fehon R.G. The tumor suppressors Merlin and Expanded function cooperatively to modulate receptor endocytosis and signaling. Curr. Biol. 2006, 16:702-709.
15. Manning G., Young S.L., Miller W.T., Zhai Y. The protist, Monosiga brevicollis, has a tyrosine kinase signaling network more elaborate and diverse than found in any known metazoan. Proc. Natl. Acad. Sci. USA 2008, 105:9674-9679.
16. McClatchey A.I., Giovannini M. Membrane organization and tumorigenesis-the NF2 tumor suppressor, Merlin. Genes Dev. 2005, 19:2265-2277.
17. Okada T., You L., Giancotti F.G. Shedding light on Merlin's wizardry. Trends Cell Biol. 2007, 17:222-229.
18. Pan D. The hippo signaling pathway in development and cancer. Dev. Cell 2010, 19:491-505.
19. Pires-daSilva A., Sommer R.J. The evolution of signalling pathways in animal development. Nat. Rev. Genet. 2003, 4:39-49.
20. Pugacheva E.N., Roegiers F., Golemis E.A. Interdependence of cell attachment and cell cycle signaling. Curr. Opin. Cell Biol. 2006, 18:507-515.
21. Reddy B.V., Irvine K.D. The Fat and Warts signaling pathways: new insights into their regulation, mechanism and conservation. Development 2008, 135:2827-2838.
22. Ronquist F., Huelsenbeck J.P. MrBayes 3: Bayesian phylogenetic inference under mixed models. Bioinformatics 2003, 19:1572-1574.
23. Ruiz-Trillo I., Burger G., Holland P.W., King N., Lang B.F., Roger A.J., Gray M.W. The origins of multicellularity: a multi-taxon genome initiative. Trends Genet. 2007, 23:113-118.
24. Scheel H., Hofmann K. A novel interaction motif, SARAH, connects three classes of tumor suppressor. Curr. Biol. 2003, 13:R899-R900.
25. Sebe-Pedros A., Roger A.J., Lang F.B., King N., Ruiz-Trillo I. Ancient origin of the integrin-mediated adhesion and signaling machinery. Proc. Natl. Acad. Sci. USA 2010, 107:10142-10147.
26. Sebe-Pedrós A., de Mendoza A., Lang B.F., Degnan B.M., Ruiz-Trillo I. Unexpected repertoire of metazoan transcription factors in the unicellular holozoan Capsaspora owczarzaki. Mol. Biol. Evol. 2011, 28:1241-1254.
27. Srivastava M., Simakov O., Chapman J., Fahey B., Gauthier M.E., Mitros T., Richards G.S., Conaco C., Dacre M., Hellsten U., et al. The Amphimedon queenslandica genome and the evolution of animal complexity. Nature 2010, 466:720-726.
28. Stamatakis A. RAxML-VI-HPC: maximum likelihood-based phylogenetic analyses with thousands of taxa and mixed models. Bioinformatics 2006, 22:2688-2690.
29. Torruella G., Derelle R., Paps J., Lang B.F., Roger A.J., Shalchian-Tabrizi K., Ruiz-Trillo I. Phylogenetic relationships within the Opisthokonta based on phylogenomic analyses of conserved single copy protein domains. Mol. Biol. Evol. 2011, Published online July 28, 2011.
30. Wu S., Liu Y., Zheng Y., Dong J., Pan D. The TEAD/TEF family protein Scalloped mediates transcriptional output of the Hippo growth-regulatory pathway. Dev. Cell 2008, 14:388-398.
31. Yoo S.J., Huh J.R., Muro I., Yu H., Wang L., Wang S.L., Feldman R.M., Clem R.J., Müller H.A., Hay B.A. Hid, Rpr and Grim negatively regulate DIAP1 levels through distinct mechanisms. Nat. Cell Biol. 2002, 4:416-424.
32. Yu J., Zheng Y., Dong J., Klusza S., Deng W.M., Pan D. Kibra functions as a tumor suppressor protein that regulates Hippo signaling in conjunction with Merlin and Expanded. Dev. Cell 2010, 18:288-299.
33. Zeng Q., Hong W. The emerging role of the hippo pathway in cell contact inhibition, organ size control, and cancer development in mammals. Cancer Cell 2008, 13:188-192.
34. Zhao B., Li L., Lei Q., Guan K.L. The Hippo-YAP pathway in organ size control and tumorigenesis: an updated version. Genes Dev. 2010, 24:862-874.