Update of the international consensus on palliative radiotherapy endpoints for future clinical trials in bone metastases

International Journal of Radiation Oncology Biology Physics

Volumn 82, Issue 5, 2012, Pages 1730-1737

  Chow, Edward ^a   Hoskin, Peter ^b   Mitera, Gunita ^a   Zeng, Liang ^a   Lutz, Stephen ^c   Roos, Daniel ^d   Hahn, Carol ^e   Van Der Linden, Yvette ^f   Hartsell, William ^g   Kumar, Eshwar ^h  

^a DEPARTMENT OF RADIATION ONCOLOGY   (Canada)

^b MOUNT VERNON HOSPITAL   (United Kingdom)

^c Blanchard Valley Regional Cancer Center   (United States)

^d ROYAL ADELAIDE HOSPITAL   (Australia)

^e DUKE UNIVERSITY MEDICAL CENTER   (United States)

^f Radiotherapeutic Institute Friesland   (Netherlands)

^g Advocate Good Samaritan Hospital   (United States)

^h SAINT JOHN REGIONAL HOSPITAL   (Canada)

Author keywords

Bone metastases; Clinical trials; Consensus; Palliative radiotherapy endpoints

Indexed keywords

BONE METASTASIS; CLINICAL TRIAL; CONSENSUS; EUROPEAN SOCIETY FOR THERAPEUTIC RADIOLOGY AND ONCOLOGY; INTERNATIONAL EXPERTS; NEW ZEALAND; PALLIATIVE RADIOTHERAPY; PATTERN CHANGE; RADIATION ONCOLOGY; REIRRADIATION; SYSTEMIC THERAPY;

EXPERIMENTS; ONCOLOGY; PATHOLOGY; RADIOLOGY; RADIOTHERAPY; SURVEYS;

BONE;

ARTICLE; BONE METASTASIS; CANCER PALLIATIVE THERAPY; CLINICAL TRIAL (TOPIC); CONSENSUS; FOLLOW UP; HUMAN; MEDICAL EXPERT; MEDICAL SOCIETY; PRIORITY JOURNAL;

AUSTRALIA; BONE NEOPLASMS; CANADA; CLINICAL TRIALS AS TOPIC; CLINICAL TRIALS, PHASE I AS TOPIC; CLINICAL TRIALS, PHASE II AS TOPIC; CONSENSUS; ENDPOINT DETERMINATION; EUROPE; FORECASTING; HUMANS; INTERNATIONALITY; NEW ZEALAND; PALLIATIVE CARE; PHYSICIAN'S PRACTICE PATTERNS; RADIATION ONCOLOGY; RETREATMENT; SOCIETIES, MEDICAL; UNITED STATES;

EID: 84857107528     PISSN: 03603016     EISSN: 1879355X     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2011.02.008     Document Type: Article

References (26)

1. Chow E, Harris K, Fan G, et al. Palliative radiotherapy trials for bone metastases: A systematic review. J Clin Oncol 2007;25:1423-1436. (Pubitemid 46706892)
2. Cole DJ. A randomized trial of a single treatment versus conventional fractionation in the palliative radiotherapy of painful bone metastases. Clin Oncol (R Coll Radiol) 1989;1:59-62.
3. Gaze MN, Kelly CG, Kerr GR, et al. Pain relief and quality of life following radiotherapy for bone metastases: A randomised trial of two fractionation schedules. Radiother Oncol 1997;45:109-116. (Pubitemid 27521081)
4. Nielsen OS, Bentzen SM, Sandberg E, et al. Randomized trial of single dose versus fractionated palliative radiotherapy of bone metastases. Radiother Oncol 1998;47:233-240. (Pubitemid 28293643)
5. Roos DE, Turner SL, O'Brien PC, et al. Randomized trial of 8 Gy in 1 versus 20 Gy in 5 fractions of radiotherapy for neuropathic pain due to bone metastases (Trans-Tasman Radiation Oncology Group, TROG 96.05). Radiother Oncol 2005;75:54-63. (Pubitemid 40616795)
6. Sze WM, Shelley MD, Held I, et al. Palliation of metastatic bone pain: Single fraction versus multifraction radiotherapy - a systematic review of randomised trials. Clin Oncol (R Coll Radiol) 2003;15:345-352. (Pubitemid 37069647)
7. Wu JS, Wong R, Johnston M, et al. Meta-analysis of dose-fractionation radiotherapy trials for the palliation of painful bone metastases. Int J Radiat Oncol Biol Phys 2003;55:594-605. (Pubitemid 36170000)
8. Chow E, Wu JSY, Hoskin P, et al. International consensus on palliative radiotherapy endpoints for future clinical trials in bone metastases. Radiother Oncol 2002;64:275-280. (Pubitemid 35254020)
9. Chow E, Davis L, Holden L, et al. A comparison of radiotherapy outcomes of bone metastases employing international consensus endpoints and traditional endpoints. Support Cancer Ther 2004;1:173-178.
10. Harstell WF, Scott CB, Bruner DW, et al. Randomized trial of short- versus long-course radiotherapy for palliation of painful bone metastases. J Natl Cancer Inst 2005;97:798-804. (Pubitemid 40909122)
11. Van Der Linden YM, Lok JJ, Steenland E, et al. Single fraction radiotherapy is efficacious: A further analysis of the dutch bone metastasis study controlling for the influence of retreatment. Int J Radiat Oncol Biol Phys 2004;59:528-537. (Pubitemid 38622611)
12. Foro AP, Fontanals AV, Galcerán JC, et al. Randomized clinical trial with two palliative radiotherapy regimens in painful bone metastases: 30 Gy in 10 fractions compared with 8 Gy in single fraction. Radiother Oncol 2008;89:150-155.
13. Hunsley J, Mash EJ. A guide to assessments that work. 1st ed. New York: Oxford University Press; 2008.
14. Pavlović I, Kern T, Miklavčič D. Comparison of paper-based and electronic data collection process in clinical trials: Costs simulation study. Contemp Clin Trials 2009;30:300-316.
15. Juniper EF, Langlands JM, Juniper BA. Patients may respond differently to paper and electronic versions of the same questionnaires. Respir Med 2009;103:932-934.
16. Kaasa S, Bjordal K, Aaronson N, et al., The EORTC core quality of life questionnaire (QLQ-C30). Validity and reliability when analysed with patients treated with palliative radiotherapy. Eur J Cancer 1995;31A:2260-2263.
17. Groenvold M, Petersen MA, Aaronson NK, et al., The development of the EORTC QLQ-C15-PAL. A shortened questionnaire for cancer patients in palliative care. Eur J Cancer 2006;42:55-64. (Pubitemid 41818953)
18. Chow E, Hird A, Velikova G, et al. The European Organisation for Research and Treatment of Cancer quality of life questionnaire for patients with bone metastases: The EORTC QLQBM22. Eur J Cancer 2009;45:1146-1152.
19. Chow E, Hoskin P, Wu J, et al. A phase III international randomized trial comparing single with multiple fractions for re-irradiation of painful bone metastases. national cancer institute of canada clinical trials group (NCIC CTG SC 20). Clin Oncol 2006;18:125-128. (Pubitemid 43169140)
20. Harris K, Li K, Flynn C, et al. Worst, average or current pain in the brief pain inventory: Which should be used to calculate the response to palliative radiotherapy in patients with bone metastases? Clin Oncol (R Coll Radiol) 2007;19:523-527. (Pubitemid 47181184)
21. Bradley NM, Chow E, Tsao MN, et al. Reasons for poor accrual in palliative radiation therapy research studies. Support Cancer Ther 2006;3:110-119.
22. Kirou-Mauro A, Harris K, Sinclair E, et al. Are family proxies a valid source of information about cancer patients' quality of life at the end-of-life? J Cancer Pain Symptom Palliat 2006;2:23-33.
23. Serlin RC, Mendoza TR, Nakamura Y, et al. When is cancer pain mild, moderate or severe? grading pain severity by its interference with function. Pain 1995;61:277-284.
24. Pollicino CA, Turner SL, Roos DE, et al. Costing the components of pain management: Analysis of Trans-Tasman Radiation Oncology Group trial (TROG 96.05): One versus five fractions for neuropathic bone pain. Radiother Oncol 2005;76:264-269. (Pubitemid 41394276)
25. van den Hout WB, van der Linden YM, Steenland E, et al. Single-versus multiple-fraction radiotherapy in patients with painful bone metastases: Cost-utility analysis based on a randomized trial. J Natl Cancer Inst 2003;95:222-229. (Pubitemid 36240635)
26. Salazar OM, Sandhu T, da Motta NW, et al. Fractionated half-body irradiation (HBI) for the rapid palliation of widespread, symptomatic, metastatic bone disease: A randomized phase III trial of the International Atomic Energy Agency (IAEA). Int J Radiat Oncol Biol Phys 2001;50:765-775. (Pubitemid 32519600)