Single fraction radiotherapy is efficacious: A further analysis of the Dutch Bone Metastasis Study controlling for the influence of retreatment

International Journal of Radiation Oncology Biology Physics

Volumn 59, Issue 2, 2004, Pages 528-537

  Van Der Linden, Yvette M ^a   Lok, Judith J ^a   Steenland, Elsbeth ^a   Martijn, Hendrik ^b   Van Houwelingen, Hans ^a   Marijnen, Corrie A M ^a   Leer, Jan Willem H ^c  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b CATHARINA HOSPITAL   (Netherlands)

^c RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Bone metastases; Pain; Radiotherapy; Response; Retreatment

Indexed keywords

BONE; RADIOTHERAPY; REGRESSION ANALYSIS; TUMORS;

MULTIPLE FRACTIONS (MF); SINGLE FRACTION (SF);

ONCOLOGY;

ADULT; AGED; ARTICLE; BONE METASTASIS; CALCULATION; CANCER PAIN; CANCER RADIOTHERAPY; CONTROLLED STUDY; DATA BASE; EVALUATION; FEMALE; HUMAN; LOGISTIC REGRESSION ANALYSIS; MAJOR CLINICAL STUDY; MALE; PALLIATIVE THERAPY; PREDICTION; PRIORITY JOURNAL; RADIATION DOSE; RANDOMIZATION; RETREATMENT;

ADULT; AGED; AGED, 80 AND OVER; ANALGESICS; BONE NEOPLASMS; DISEASE PROGRESSION; FEMALE; HUMANS; LOGISTIC MODELS; MALE; MIDDLE AGED; NETHERLANDS; PAIN; PAIN MEASUREMENT; PROPORTIONAL HAZARDS MODELS; RADIOTHERAPY DOSAGE; RETREATMENT; TIME FACTORS; TREATMENT OUTCOME;

EID: 2442420056     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2003.10.006     Document Type: Article

References (28)

1. Nielsen O.S., Bentzen S.M., Sandberg E., et al. Randomized trial of single dose versus fractionated palliative radiotherapy of bone metastases. Radiother Oncol. 47:1998;233-240
2. Gaze M.N., Kelly C.G., Kerr G.R., et al. Pain relief and quality of life following radiotherapy for bone metastases A randomised trial of two fractionation schedules. Radiother Oncol. 45:1997;109-116
3. Price P., Hoskin P.J., Easton D., et al. Prospective randomised trial of single and multifraction radiotherapy schedules in the treatment of painful bony metastases. Radiother Oncol. 6:1986;247-255
4. Cole D.J. A randomized trial of a single treatment versus conventional fractionation in the palliative radiotherapy of painful bone metastases. Clin Oncol (R Coll Radiol). 1:1989;59-62
5. Steenland E., Leer J.W., van Houwelingen H., et al. The effect of a single fraction compared to multiple fractions on painful bone metastases A global analysis of the Dutch Bone Metastasis Study. Radiother Oncol. 52:1999;101-109
6. 8 Gy single fraction radiotherapy for the treatment of metastatic skeletal pain: Randomised comparison with a multifraction schedule over 12 months of patient follow-up. Bone Pain Trial Working Party. Radiother Oncol 1999;52:111-121
7. Koswig S., Budach V. Remineralization and pain relief in bone metastases after different radiotherapy fractions (10 times 3 Gy vs. 1 time 8 Gy). A prospective study. Strahlenther Onkol. 175:1999;500-508
8. Tong D., Gillick L., Hendrickson F.R. The palliation of symptomatic osseous metastases Final results of the Study by the Radiation Therapy Oncology Group. Cancer. 50:1982;893-899
9. Niewald M., Tkocz H.J., Abel U., et al. Rapid course radiation therapy vs. more standard treatment A randomized trial for bone metastases. Int J Radiat Oncol Biol Phys. 36:1996;1085-1089
10. Rasmusson B., Vejborg I., Jensen A.B., et al. Irradiation of bone metastases in breast cancer patients A randomized study with 1 year follow-up. Radiother Oncol. 34:1995;179-184
11. Madsen E.L. Painful bone metastasis Efficacy of radiotherapy assessed by the patients: A randomized trial comparing 4 Gy × 6 versus 10 Gy × 2. Int J Radiat Oncol Biol Phys. 9:1983;1775-1779
12. Jeremic B., Shibamoto Y., Acimovic L., et al. A randomized trial of three single-dose radiation therapy regimens in the treatment of metastatic bone pain. Int J Radiat Oncol Biol Phys. 42:1998;161-167
13. Hoskin P.J., Price P., Easton D., et al. A prospective randomised trial of 4 Gy or 8 Gy single doses in the treatment of metastatic bone pain. Radiother Oncol. 23:1992;74-78
14. Price P., Hoskin P.J., Easton D., et al. Low dose single fraction radiotherapy in the treatment of metastatic bone pain A pilot study. Radiother Oncol. 12:1988;297-300
15. Uppelschoten J.M., Wanders S.L., de Jong J.M. Single-dose radiotherapy (6 Gy) Palliation in painful bone metastases. Radiother Oncol. 36:1995;198-202
16. Blitzer P.H. Reanalysis of the RTOG study of the palliation of symptomatic osseous metastasis. Cancer. 55:1985;1468-1472
17. Okawa T., Kita M., Goto M., Nishijima H., Miyaji N. Randomized prospective clinical study of small, large and twice-a-day fraction radiotherapy for painful bone metastases. Radiother Oncol. 13:1988;99-104
18. Ratanatharathorn V., Powers W.E., Moss W.T., et al. Bone metastasis Review and critical analysis of random allocation trials of local field treatment. Int J Radiat Oncol Biol Phys. 44:1999;1-18
19. Roos D.E. Continuing reluctance to use single fractions of radiotherapy for metastatic bone pain An Australian and New Zealand practice survey and literature review. Radiother Oncol. 56:2000;315-322
20. Jeremic B. Single fraction external beam radiation therapy in the treatment of localized metastatic bone pain. A review. J Pain Symptom Manage. 22:2001;1048-1058
21. McQuay HJ, Collins SL, Carroll D. Radiotherapy for the palliation of painful bone metastases (Cochrane review). The Cochrane Library, Issue 1, 2002. Oxford, UK
22. Wu J.S., Wong R., Johnston M., et al. Meta-analysis of dose-fractionation radiotherapy trials for the palliation of painful bone metastases. Int J Radiat Oncol Biol Phys. 55:2003;594-605
23. Chow E, Wu J, Hoskin P, et al. International consensus on palliative radiotherapy endpoints for future clinical trials in bone metastases. Radiother Oncol 2002;64:275-280
24. Jensen M.P., Karoly P., Braver S. The measurement of clinical pain intensity A comparison of six methods. Pain. 27:1986;117-126
25. de Haes H, Olschewski M, Fayers P, et al. Measuring the quality of life of cancer patients with the Rotterdam Symptom Checklist (RSCL): A manual. Northern Centre for Healthcare Research. 1996. Groningen, the Netherlands
26. Mithal N.P., Needham P.R., Hoskin P.J. Retreatment with radiotherapy for painful bone metastases. Int J Radiat Oncol Biol Phys. 29:1994;1011-1014
27. Jeremic B., Shibamoto Y., Igrutinovic I. Single 4 Gy re-irradiation for painful bone metastasis following single fraction radiotherapy. Radiother Oncol. 52:1999;123-127
28. Jeremic B., Shibamoto Y., Igrutinovic I. Second single 4 Gy reirradiation for painful bone metastasis. J Pain Symptom Manage. 23:2002;26-30