Intranasal administration of poly(I:C) and LPS in BALB/C mice induces airway hyperresponsiveness and inflammation via different pathways

PLoS ONE

Volumn 7, Issue 2, 2012, Pages

  Starkhammar, Magnus ^a,b   Georén, Susanna ^a,b   Swedin, Linda ^b   Dahlén, Sven Erik ^b   Adner, Mikael ^b   Cardell, Lars Olaf ^a,b  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b KAROLINSKA INSTITUTE   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

CXCL1 CHEMOKINE; CXCL9 CHEMOKINE; ESCHERICHIA COLI LIPOPOLYSACCHARIDE; FIBROBLAST GROWTH FACTOR; GAMMA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 13; INTERLEUKIN 17; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN 6; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; METHACHOLINE; MONOCYTE CHEMOTACTIC PROTEIN 1; POLYINOSINIC POLYCYTIDYLIC ACID; RANTES; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA; VASCULOTROPIN; BRONCHOCONSTRICTING AGENT; CYTOKINE; INTERFERON INDUCING AGENT; LIPOPOLYSACCHARIDE; METHACHOLINE CHLORIDE; MYD88 PROTEIN, MOUSE; MYELOID DIFFERENTIATION FACTOR 88;

AIRWAY HYPERRESPONSIVENESS; AIRWAY RESISTANCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FEMALE; HISTOPATHOLOGY; LUNG LAVAGE; LUNG MECHANICS; LUNG PARENCHYMA; LYMPHOCYTE; MOUSE; NEUTROPHIL; NONHUMAN; PROVOCATION TEST; RESPIRATORY TRACT DISEASE; RESPIRATORY TRACT INFLAMMATION; ANIMAL; BAGG ALBINO MOUSE; BREATHING MECHANICS; BRONCHUS HYPERREACTIVITY; CHEMICALLY INDUCED DISORDER; DRUG EFFECT; IMMUNOLOGY; INFLAMMATION; INTRANASAL DRUG ADMINISTRATION; METABOLISM; MOUSE MUTANT; PHYSIOLOGY; SIGNAL TRANSDUCTION;

BACTERIA (MICROORGANISMS); MUS;

ADMINISTRATION, INTRANASAL; AIRWAY RESISTANCE; ANIMALS; BRONCHIAL HYPERREACTIVITY; BRONCHOALVEOLAR LAVAGE; BRONCHOCONSTRICTOR AGENTS; CYTOKINES; FEMALE; INFLAMMATION; INTERFERON INDUCERS; LIPOPOLYSACCHARIDES; METHACHOLINE CHLORIDE; MICE; MICE, INBRED BALB C; MICE, KNOCKOUT; MYELOID DIFFERENTIATION FACTOR 88; POLY I-C; RESPIRATORY MECHANICS; SIGNAL TRANSDUCTION;

EID: 84857088896     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0032110     Document Type: Article

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