Comparison of aerosol and intranasal challenge in a mouse model of allergic airway inflammation and hyperresponsiveness

International Archives of Allergy and Immunology

Volumn 153, Issue 3, 2010, Pages 249-258

  Swedin, Linda ^a   Ellis, Russ ^b   Kemi, Cecilia ^a   Ryrfeldt, Ke ^a   Inman, Mark ^b   Dahlén, Sven Erik ^a   Adner, Mikael ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b MCMASTER UNIVERSITY   (Canada)

Author keywords

Airway responsiveness; Challenge; Mouse strain; Protocol optimization; Sensitization

Indexed keywords

ELASTASE; METHACHOLINE; OVALBUMIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL COUNT; CELL INFILTRATION; COMPARATIVE STUDY; EOSINOPHIL; FEMALE; HISTOPATHOLOGY; LUNG LAVAGE; LUNG RESISTANCE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RESPIRATORY TRACT ALLERGY; SENSITIZATION;

ADMINISTRATION, INTRANASAL; AEROSOLS; ANIMALS; BRONCHIAL HYPERREACTIVITY; DISEASE MODELS, ANIMAL; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; OVALBUMIN;

EID: 77952300905     PISSN: 10182438     EISSN: None     Source Type: Journal    
DOI: 10.1159/000314365     Document Type: Article

References (32)

1. Nials AT, Uddin S: Mouse models of allergic asthma: acute and chronic allergen challenge. Dis Model Mech 2008; 1:213-220.
2. Zhang Y, Lamm WJ, Albert RK, Chi EY, Henderson WR Jr, Lewis DB: Influence of the route of allergen administration and genetic background on the murine allergic pulmonary response. Am J Respir Crit Care Med 1997; 155:661-669.
3. Chang YS, Kim YK, Bahn JW, Kim SH, Park HW, Kim TB, Cho SH, Min KU, Kim YY: Comparison of asthma phenotypes using different sensitizing protocols in mice. Korean J Intern Med 2005; 20:152-158.
4. Nelde A, Teufel M, Ha hn C , Dusch l A, S eba ld W, Brocker EB, Grunewald SM: The impact of the route and frequency of antigen exposure on the IgE response in allergy. Int Arch Allergy Immunol 2001; 124:461-469.
5. Whitehead GS, Walker JK, Berman KG, Foster WM, Schwartz DA: Allergen-induced airway disease is mouse strain dependent. Am J Physiol 2003; 285:L32-L42.
6. Brewer JP, Kisselgof AB, Martin TR: Genetic variability in pulmonary physiological, cellular, and antibody responses to antigen in mice. Am J Respir Crit Care Med 1999; 160: 1150-1156.
7. Swedin L, Neimert-Andersson T, Hjoberg J, Jonasson S, Van Hage M, Adner M, Ryrfeldt A, Da h len SE: Di ssociation of air way i nf la m-mation and hyperresponsiveness by cyclo-oxygenase inhibition in allergen challenged mice. Eur Respir J 2009;34:200-208.
8. Jonasson S, Swedin L, Lundqvist M, Heden-stierna G, Dahlen SE, Hjoberg J: Different effects of deep inspirations on central and peripheral airways in healthy and allergen-challenged mice. Respir Res 2008; 9: 23.
9. Barnas GM, Ho G, Green MD, Harinath P, Smalley AJ, Campbell DN, Mendham JE: Effects of analysis method and forcing waveform on measurement of respiratory mechanics. Respir Physiol 1992; 89:273-285.
10. Tomioka S, Bates JH, Irvin CG: Airway and tissue mechanics in a murine model of asthma: alveolar capsule vs forced oscillations. J Appl Physiol 20 02; 93: 263-270.
11. Hjoberg J, Shore S, Kobzik L, Okinaga S, Hal-lock A, Vallone J, Subramaniam V, De Sanc-tis GT, Elias JA, Drazen JM, Silverman ES: Expression of nitric oxide synthase-2 in the lungs decreases airway resistance and responsiveness. J Appl Physiol 2004; 97:249-259.
12. Hantos Z, Daroczy B, Suki B, Nagy S, Fred-berg JJ: Input impedance and peripheral in-homogeneity of dog lungs. J Appl Physiol 19 92 ; 72: 168-17 8.
13. Irvin CG, Bates JH: Measuring the lung function in the mouse: the challenge of size. Respir Res 2003; 4:4.
14. Bates JH, Irvin CG: Measuring lung function in mice: the phenotyping uncertainty principle. J Appl Physiol 20 03; 94: 1297-1306.
15. Bates JH, Lutchen KR: The interface between measurement and modeling of peripheral lung mechanics. Respir Physiol Neurobiol 2005; 148: 153-164.
16. Ellis R, Leigh R, Southam D, O'Byrne PM, Inman MD: Morphometric analysis of mouse airways after chronic allergen challenge. Lab Invest 2003; 83:1285-1291.
17. Leigh R, Ellis R, Wattie J, Southam DS, De Hoogh M, Gauldie J, O'Byrne PM, Inman MD: Dysfunction and remodelling of the mouse airway persist after resolution of acute allergen-induced airway inflammation. Am J Respir Cell Mol Biol 2002; 27:526-535.
18. Leigh R, Ellis R, Wattie JN, Hirota JA, Mat-thaei KI, Foster PS, O'Byrne PM, Inman MD: Type 2 cytokines in the pathogenesis of sustained airway dysfunction and airway remodeling in mice. Am J Respir Crit Care Med 2004; 169:860-867.
19. Leigh R, Southam DS, Ellis R, Wattie JN, Sehmi R, Wan Y, Inman MD: T-cell-mediat-ed inflammation does not contribute to the maintenance of airway dysfunction in mice. J Appl Physiol 2004; 97:2258-2265.
20. Southam DS, Ellis R, Wattie J, Inman MD: Components of airway hyperresponsiveness and their associations with inflammation and remodeling in mice. J Allergy Clin Immunol 2007; 119:848-854.
21. Inman MD, Ellis R, Wattie J, Denburg JA, O'Byrne PM: Allergen-induced increase in airway responsiveness, airway eosinophilia, and bone-marrow eosinophil progenitors in mice. Am J Respir Cell Mol Biol 1999; 21: 473-479.
22. Boost KA, Flondor M, Hofstetter C, Platacis I, Stegewerth K, Hoegl S, Nguyen T, Muhl H, Zwissler B: The |3-adrenoceptor antagonist propranolol counteracts anti-inflammatory effects of isoflurane in rat endotoxemia. Acta Anaesthesiol Scand 2007; 51: 900-908.
23. Reutershan J, Chang D, Hayes JK, Ley K: Protective effects of isoflurane pretreatment in endotoxin-induced lung injury. Anesthesiology 2006; 104: 511-517.
24. Williams CM, Galli SJ: Mast cells can amplify airway reactivity and features of chronic inflammation in an asthma model in mice. J Exp Med 2000; 192: 455-462.
25. Zhu W, Gilmour MI: Comparison of allergic lung disease in three mouse strains after systemic or mucosal sensitization with ovalbumin antigen. Immunogenetics 2009; 61: 199-207.
26. Yu M, Tsai M, Tam SY, Jones C, Zehnder J, Galli SJ: Mast cells can promote the development of multiple features of chronic asthma in mice. J Clin Invest 2006; 116:1633-1641.
27. Wagers SS, Haverkamp HC, Bates JH, Norton RJ, Thompson-Figueroa JA, Sullivan MJ, Irvin CG: Intrinsic and antigen-induced airway hyperresponsiveness are the result of diverse physiological mechanisms. J Appl Physiol 2007; 10 2: 221-230.
28. Takeda K, Haczku A, Lee JJ, Irvin CG, Gel-fand EW: Strain dependence of airway hy-perresponsiveness reflects differences in eo-sinophil localization in the lung. Am J Physiol 2001; 281:L394-L402.
29. Gueders MM, Paulissen G, Crahay C, Que-sada-Calvo F, Hacha J, Van Hove C, Tournoy K, Louis R, Foidart JM, Noel A, Cataldo DD: Mouse models of asthma: a comparison between C57BL/6and BALB/c strains regarding bronchial responsiveness, inf lammation, and cytokine production. Inflamm Res 2009;58:845-854.
30. Jonasson S, Hedenstierna G, Hedenstrom H, Hjoberg J: Comparisons of effects of intravenous and inhaled methacholine on airway physiology in a murine asthma model. Respir Physiol Neurobiol 2009; 165:229-236.
31. Zosk y GR, Larcombe AN, W hite OJ, Burchell JT, Von Garnier C, Holt PG, Turner DJ, Wik-strom ME, Sly PD, Stumbles PA: Airway hy-perresponsiveness is associated with activated CD4+ T cells in the airways Am J Physiol 2009 297 L373-L379.
32. Van Hove CL, Maes T, Cataldo DD, Gueders MM, Palmans E, Joos GF, Tournoy KG: Comparison of acute inflammatory and chronic structural asthma-like responses between C57BL/6and BALB/c mice. Int Arch Allergy Immunol 2009; 149 : 195-207.