Repeated exposure to aspergillus fumigatus conidia results in CD4 + T cell-dependent and -independent pulmonary arterial remodeling in a mixed th1/th2/th17 microenvironment that requires interleukin-4 (IL-4) and IL-10

Infection and Immunity

Volumn 80, Issue 1, 2012, Pages 388-397

  Shreiner, Andrew B ^a   Murdock, Benjamin J ^a   Akha, Amir A Sadighi ^a   Falkowski, Nicole R ^a   Christensen, Paul J ^a,b   White, Eric S ^a   Hogaboam, Cory M ^a   Huffnagle, Gary B ^a,b  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b VA ANN ARBOR HEALTHCARE SYSTEM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 17; INTERLEUKIN 4; IL10 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; ASPERGILLUS FUMIGATUS; CD4+ T LYMPHOCYTE; CONIDIUM; CONTROLLED STUDY; CYTOKINE PRODUCTION; EXPOSURE; FLOW CYTOMETRY; LYMPHOCYTE FUNCTION; MICROENVIRONMENT; MOUSE; NONHUMAN; PRIORITY JOURNAL; PULMONARY VASCULAR DISEASE; TH1 CELL; TH17 CELL; TH2 CELL; ANIMAL; C57BL MOUSE; FUNGUS SPORE; IMMUNOLOGY; LUNG; MICROBIOLOGY; NEOVASCULARIZATION (PATHOLOGY); PATHOGENICITY; PATHOLOGY;

ANIMALS; ASPERGILLUS FUMIGATUS; CD4-POSITIVE T-LYMPHOCYTES; INHALATION EXPOSURE; INTERLEUKIN-10; INTERLEUKIN-4; LUNG; MICE; MICE, INBRED C57BL; NEOVASCULARIZATION, PATHOLOGIC; SPORES, FUNGAL; TH1 CELLS; TH17 CELLS; TH2 CELLS;

EID: 84857070599     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.05530-11     Document Type: Article

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