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Volumn 318, Issue 5, 2012, Pages 558-569

Protein kinase D1 stimulates proliferation and enhances tumorigenesis of MCF-7 human breast cancer cells through a MEK/ERK-dependent signaling pathway

Author keywords

Breast cancer; Proliferation; Protein kinase D1; Signal transduction; Tumorigenesis

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN KINASE D; PROTEIN KINASE D1; UNCLASSIFIED DRUG;

EID: 84857058592     PISSN: 00144827     EISSN: 10902422     Source Type: Journal    
DOI: 10.1016/j.yexcr.2012.01.001     Document Type: Article
Times cited : (46)

References (47)
  • 1
    • 0032496417 scopus 로고    scopus 로고
    • Rapid activation of the novel serine/threonine protein kinase, protein kinase D by phorbol esters, angiotensin II and PDGF-BB in vascular smooth muscle cells
    • Abedi H., Rozengurt E., Zachary I. Rapid activation of the novel serine/threonine protein kinase, protein kinase D by phorbol esters, angiotensin II and PDGF-BB in vascular smooth muscle cells. FEBS Lett. 1998, 427:209-212.
    • (1998) FEBS Lett. , vol.427 , pp. 209-212
    • Abedi, H.1    Rozengurt, E.2    Zachary, I.3
  • 2
    • 77950232143 scopus 로고    scopus 로고
    • Protein kinase D1 inhibits cell proliferation through matrix metalloproteinase-2 and matrix metalloproteinase-9 secretion in prostate cancer
    • Biswas M.H., Du C., Zhang C., Straubhaar J., Languino L.R., Balaji K.C. Protein kinase D1 inhibits cell proliferation through matrix metalloproteinase-2 and matrix metalloproteinase-9 secretion in prostate cancer. Cancer Res. 2010, 70:2095-2104.
    • (2010) Cancer Res. , vol.70 , pp. 2095-2104
    • Biswas, M.H.1    Du, C.2    Zhang, C.3    Straubhaar, J.4    Languino, L.R.5    Balaji, K.C.6
  • 3
    • 0035902180 scopus 로고    scopus 로고
    • Oncogenic kinase signalling
    • Blume-Jensen P., Hunter T. Oncogenic kinase signalling. Nature 2001, 411:355-365.
    • (2001) Nature , vol.411 , pp. 355-365
    • Blume-Jensen, P.1    Hunter, T.2
  • 5
    • 45549091994 scopus 로고    scopus 로고
    • Protein kinase D3 (PKD3) contributes to prostate cancer cell growth and survival through a PKCepsilon/PKD3 pathway downstream of Akt and ERK 1/2
    • Chen J., Deng F., Singh S.V., Wang Q.J. Protein kinase D3 (PKD3) contributes to prostate cancer cell growth and survival through a PKCepsilon/PKD3 pathway downstream of Akt and ERK 1/2. Cancer Res. 2008, 68:3844-3853.
    • (2008) Cancer Res. , vol.68 , pp. 3844-3853
    • Chen, J.1    Deng, F.2    Singh, S.V.3    Wang, Q.J.4
  • 6
    • 0034996179 scopus 로고    scopus 로고
    • PKD in intestinal epithelial cells: rapid activation by phorbol esters, LPA, and angiotensin through PKC
    • Chiu T., Rozengurt E. PKD in intestinal epithelial cells: rapid activation by phorbol esters, LPA, and angiotensin through PKC. Am. J. Physiol. Cell Physiol. 2001, 280:C929-C942.
    • (2001) Am. J. Physiol. Cell Physiol. , vol.280
    • Chiu, T.1    Rozengurt, E.2
  • 7
    • 0025001402 scopus 로고
    • The process of malignant progression in human breast cancer
    • Clarke R., Dickson R.B., Brunner N. The process of malignant progression in human breast cancer. Ann. Oncol. 1990, 1:401-407.
    • (1990) Ann. Oncol. , vol.1 , pp. 401-407
    • Clarke, R.1    Dickson, R.B.2    Brunner, N.3
  • 9
    • 67549112510 scopus 로고    scopus 로고
    • Protein kinase D1 regulates matrix metalloproteinase expression and inhibits breast cancer cell invasion
    • Eiseler T., Doppler H., Yan I.K., Goodison S., Storz P. Protein kinase D1 regulates matrix metalloproteinase expression and inhibits breast cancer cell invasion. Breast Cancer Res. 2009, 11:R13.
    • (2009) Breast Cancer Res. , vol.11
    • Eiseler, T.1    Doppler, H.2    Yan, I.K.3    Goodison, S.4    Storz, P.5
  • 10
    • 77953315696 scopus 로고    scopus 로고
    • Protein kinase D controls actin polymerization and cell motility through phosphorylation of cortactin
    • Eiseler T., Hausser A., De K.L., Van L.J., Pfizenmaier K. Protein kinase D controls actin polymerization and cell motility through phosphorylation of cortactin. J. Biol. Chem. 2010, 285:18672-18683.
    • (2010) J. Biol. Chem. , vol.285 , pp. 18672-18683
    • Eiseler, T.1    Hausser, A.2    De, K.L.3    Van, L.J.4    Pfizenmaier, K.5
  • 11
  • 12
    • 0035919923 scopus 로고    scopus 로고
    • Phosphorylation of ERK1/2 mitogen-activated protein kinase is associated with poor response to anti-hormonal therapy and decreased patient survival in clinical breast cancer
    • Gee J.M., Robertson J.F., Ellis I.O., Nicholson R.I. Phosphorylation of ERK1/2 mitogen-activated protein kinase is associated with poor response to anti-hormonal therapy and decreased patient survival in clinical breast cancer. Int. J. Cancer 2001, 95:247-254.
    • (2001) Int. J. Cancer , vol.95 , pp. 247-254
    • Gee, J.M.1    Robertson, J.F.2    Ellis, I.O.3    Nicholson, R.I.4
  • 13
    • 0030603158 scopus 로고    scopus 로고
    • Inhibition of protein kinase C mu by various inhibitors. Differentiation from protein kinase c isoenzymes
    • Gschwendt M., Dieterich S., Rennecke J., Kittstein W., Mueller H.J., Johannes F.J. Inhibition of protein kinase C mu by various inhibitors. Differentiation from protein kinase c isoenzymes. FEBS Lett. 1996, 392:77-80.
    • (1996) FEBS Lett. , vol.392 , pp. 77-80
    • Gschwendt, M.1    Dieterich, S.2    Rennecke, J.3    Kittstein, W.4    Mueller, H.J.5    Johannes, F.J.6
  • 14
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan D., Weinberg R.A. The hallmarks of cancer. Cell 2000, 100:57-70.
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 16
    • 0034523626 scopus 로고    scopus 로고
    • Inhibition of mitogen-activated protein kinase kinase selectively inhibits cell proliferation in human breast cancer cells displaying enhanced insulin-like growth factor I-mediated mitogen-activated protein kinase activation
    • Hermanto U., Zong C.S., Wang L.H. Inhibition of mitogen-activated protein kinase kinase selectively inhibits cell proliferation in human breast cancer cells displaying enhanced insulin-like growth factor I-mediated mitogen-activated protein kinase activation. Cell Growth Differ. 2000, 11:655-664.
    • (2000) Cell Growth Differ. , vol.11 , pp. 655-664
    • Hermanto, U.1    Zong, C.S.2    Wang, L.H.3
  • 18
    • 0028000009 scopus 로고
    • Activation of the Ras signalling pathway in human breast cancer cells overexpressing erbB-2
    • Janes P.W., Daly R.J., deFazio A., Sutherland R.L. Activation of the Ras signalling pathway in human breast cancer cells overexpressing erbB-2. Oncogene 1994, 9:3601-3608.
    • (1994) Oncogene , vol.9 , pp. 3601-3608
    • Janes, P.W.1    Daly, R.J.2    deFazio, A.3    Sutherland, R.L.4
  • 20
    • 25644447454 scopus 로고    scopus 로고
    • Up-regulation of PI3K/Akt signaling by 17beta-estradiol through activation of estrogen receptor-alpha, but not estrogen receptor-beta, and stimulates cell growth in breast cancer cells
    • Lee Y.R., Park J., Yu H.N., Kim J.S., Youn H.J., Jung S.H. Up-regulation of PI3K/Akt signaling by 17beta-estradiol through activation of estrogen receptor-alpha, but not estrogen receptor-beta, and stimulates cell growth in breast cancer cells. Biochem. Biophys. Res. Commun. 2005, 336:1221-1226.
    • (2005) Biochem. Biophys. Res. Commun. , vol.336 , pp. 1221-1226
    • Lee, Y.R.1    Park, J.2    Yu, H.N.3    Kim, J.S.4    Youn, H.J.5    Jung, S.H.6
  • 23
    • 0034691562 scopus 로고    scopus 로고
    • Potential prognostic value of mitogen-activated protein kinase activity for disease-free survival of primary breast cancer patients
    • Mueller H., Flury N., Eppenberger-Castori S., Kueng W., David F., Eppenberger U. Potential prognostic value of mitogen-activated protein kinase activity for disease-free survival of primary breast cancer patients. Int. J. Cancer 2000, 89:384-388.
    • (2000) Int. J. Cancer , vol.89 , pp. 384-388
    • Mueller, H.1    Flury, N.2    Eppenberger-Castori, S.3    Kueng, W.4    David, F.5    Eppenberger, U.6
  • 24
    • 0033083095 scopus 로고    scopus 로고
    • Protein kinase D in small cell lung cancer cells: rapid activation through protein kinase C
    • Paolucci L., Rozengurt E. Protein kinase D in small cell lung cancer cells: rapid activation through protein kinase C. Cancer Res. 1999, 59:572-577.
    • (1999) Cancer Res. , vol.59 , pp. 572-577
    • Paolucci, L.1    Rozengurt, E.2
  • 25
    • 17144414861 scopus 로고    scopus 로고
    • Protein kinase D1 phosphorylates HDAC7 and induces its nuclear export after T-cell receptor activation
    • Parra M., Kasler H., McKinsey T.A., Olson E.N., Verdin E. Protein kinase D1 phosphorylates HDAC7 and induces its nuclear export after T-cell receptor activation. J. Biol. Chem. 2005, 280:13762-13770.
    • (2005) J. Biol. Chem. , vol.280 , pp. 13762-13770
    • Parra, M.1    Kasler, H.2    McKinsey, T.A.3    Olson, E.N.4    Verdin, E.5
  • 26
    • 67651005347 scopus 로고    scopus 로고
    • Protein kinase D regulates cell migration by direct phosphorylation of the cofilin phosphatase slingshot 1 like
    • Peterburs P., Heering J., Link G., Pfizenmaier K., Olayioye M.A., Hausser A. Protein kinase D regulates cell migration by direct phosphorylation of the cofilin phosphatase slingshot 1 like. Cancer Res. 2009, 69:5634-5638.
    • (2009) Cancer Res. , vol.69 , pp. 5634-5638
    • Peterburs, P.1    Heering, J.2    Link, G.3    Pfizenmaier, K.4    Olayioye, M.A.5    Hausser, A.6
  • 28
    • 34247890106 scopus 로고    scopus 로고
    • Inhibition of the MAP kinase activity suppresses estrogen-induced breast tumor growth both in vitro and in vivo
    • Reddy K.B., Glaros S. Inhibition of the MAP kinase activity suppresses estrogen-induced breast tumor growth both in vitro and in vivo. Int. J. Oncol. 2007, 30:971-975.
    • (2007) Int. J. Oncol. , vol.30 , pp. 971-975
    • Reddy, K.B.1    Glaros, S.2
  • 29
    • 0033524222 scopus 로고    scopus 로고
    • Protein-kinase-Cmu expression correlates with enhanced keratinocyte proliferation in normal and neoplastic mouse epidermis and in cell culture
    • Rennecke J., Rehberger P.A., Furstenberger G., Johannes F.J., Stohr M., Marks F., Richter K.H. Protein-kinase-Cmu expression correlates with enhanced keratinocyte proliferation in normal and neoplastic mouse epidermis and in cell culture. Int. J. Cancer 1999, 80:98-103.
    • (1999) Int. J. Cancer , vol.80 , pp. 98-103
    • Rennecke, J.1    Rehberger, P.A.2    Furstenberger, G.3    Johannes, F.J.4    Stohr, M.5    Marks, F.6    Richter, K.H.7
  • 31
    • 0029558776 scopus 로고
    • Protein kinase D (PKD): a novel target for diacylglycerol and phorbol esters
    • Rozengurt E., Sinnett-Smith J., Van L.J., Valverde A.M. Protein kinase D (PKD): a novel target for diacylglycerol and phorbol esters. Mutat. Res. 1995, 333:153-160.
    • (1995) Mutat. Res. , vol.333 , pp. 153-160
    • Rozengurt, E.1    Sinnett-Smith, J.2    Van, L.J.3    Valverde, A.M.4
  • 32
    • 1942425961 scopus 로고    scopus 로고
    • Protein kinase D potentiates DNA synthesis induced by Gq-coupled receptors by increasing the duration of ERK signaling in swiss 3T3 cells
    • Sinnett-Smith J., Zhukova E., Hsieh N., Jiang X., Rozengurt E. Protein kinase D potentiates DNA synthesis induced by Gq-coupled receptors by increasing the duration of ERK signaling in swiss 3T3 cells. J. Biol. Chem. 2004, 279:16883-16893.
    • (2004) J. Biol. Chem. , vol.279 , pp. 16883-16893
    • Sinnett-Smith, J.1    Zhukova, E.2    Hsieh, N.3    Jiang, X.4    Rozengurt, E.5
  • 33
    • 0030946366 scopus 로고    scopus 로고
    • Hyperexpression of mitogen-activated protein kinase in human breast cancer
    • Sivaraman V.S., Wang H., Nuovo G.J., Malbon C.C. Hyperexpression of mitogen-activated protein kinase in human breast cancer. J. Clin. Invest. 1997, 99:1478-1483.
    • (1997) J. Clin. Invest. , vol.99 , pp. 1478-1483
    • Sivaraman, V.S.1    Wang, H.2    Nuovo, G.J.3    Malbon, C.C.4
  • 34
    • 0037413711 scopus 로고    scopus 로고
    • Protein kinase D mediates a stress-induced NF-kappaB activation and survival pathway
    • Storz P., Toker A. Protein kinase D mediates a stress-induced NF-kappaB activation and survival pathway. EMBO J. 2003, 22:109-120.
    • (2003) EMBO J. , vol.22 , pp. 109-120
    • Storz, P.1    Toker, A.2
  • 37
    • 0027964870 scopus 로고
    • Molecular cloning and characterization of protein kinase D: a target for diacylglycerol and phorbol esters with a distinctive catalytic domain
    • Valverde A.M., Sinnett-Smith J., Van L.J., Rozengurt E. Molecular cloning and characterization of protein kinase D: a target for diacylglycerol and phorbol esters with a distinctive catalytic domain. Proc. Natl. Acad. Sci. U. S. A. 1994, 91:8572-8576.
    • (1994) Proc. Natl. Acad. Sci. U. S. A. , vol.91 , pp. 8572-8576
    • Valverde, A.M.1    Sinnett-Smith, J.2    Van, L.J.3    Rozengurt, E.4
  • 38
    • 0028881513 scopus 로고
    • Expression and characterization of PKD, a phorbol ester and diacylglycerol-stimulated serine protein kinase
    • Van Lint J.V., Sinnett-Smith J., Rozengurt E. Expression and characterization of PKD, a phorbol ester and diacylglycerol-stimulated serine protein kinase. J. Biol. Chem. 1995, 270:1455-1461.
    • (1995) J. Biol. Chem. , vol.270 , pp. 1455-1461
    • Van Lint, J.V.1    Sinnett-Smith, J.2    Rozengurt, E.3
  • 39
    • 0032549694 scopus 로고    scopus 로고
    • Platelet-derived growth factor stimulates protein kinase D through the activation of phospholipase Cgamma and protein kinase C
    • Van L.J., Ni Y., Valius M., Merlevede W., Vandenheede J.R. Platelet-derived growth factor stimulates protein kinase D through the activation of phospholipase Cgamma and protein kinase C. J. Biol. Chem. 1998, 273:7038-7043.
    • (1998) J. Biol. Chem. , vol.273 , pp. 7038-7043
    • Van, L.J.1    Ni, Y.2    Valius, M.3    Merlevede, W.4    Vandenheede, J.R.5
  • 40
    • 4544315655 scopus 로고    scopus 로고
    • Protein kinases C and D mediate agonist-dependent cardiac hypertrophy through nuclear export of histone deacetylase 5
    • Vega R.B., Harrison B.C., Meadows E., Roberts C.R., Papst P.J., Olson E.N., McKinsey T.A. Protein kinases C and D mediate agonist-dependent cardiac hypertrophy through nuclear export of histone deacetylase 5. Mol. Cell. Biol. 2004, 24:8374-8385.
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 8374-8385
    • Vega, R.B.1    Harrison, B.C.2    Meadows, E.3    Roberts, C.R.4    Papst, P.J.5    Olson, E.N.6    McKinsey, T.A.7
  • 41
    • 33744926666 scopus 로고    scopus 로고
    • PKD at the crossroads of DAG and PKC signaling
    • Wang Q.J. PKD at the crossroads of DAG and PKC signaling. Trends Pharmacol. Sci. 2006, 27:317-323.
    • (2006) Trends Pharmacol. Sci. , vol.27 , pp. 317-323
    • Wang, Q.J.1
  • 44
    • 25844484590 scopus 로고    scopus 로고
    • Protein kinase C-dependent protein kinase D activation modulates ERK signal pathway and endothelial cell proliferation by vascular endothelial growth factor
    • Wong C., Jin Z.G. Protein kinase C-dependent protein kinase D activation modulates ERK signal pathway and endothelial cell proliferation by vascular endothelial growth factor. J. Biol. Chem. 2005, 280:33262-33269.
    • (2005) J. Biol. Chem. , vol.280 , pp. 33262-33269
    • Wong, C.1    Jin, Z.G.2
  • 45
    • 3342906957 scopus 로고    scopus 로고
    • PKD1/PKCmu promotes alphavbeta3 integrin recycling and delivery to nascent focal adhesions
    • Woods A.J., White D.P., Caswell P.T., Norman J.C. PKD1/PKCmu promotes alphavbeta3 integrin recycling and delivery to nascent focal adhesions. EMBO J. 2004, 23:2531-2543.
    • (2004) EMBO J. , vol.23 , pp. 2531-2543
    • Woods, A.J.1    White, D.P.2    Caswell, P.T.3    Norman, J.C.4
  • 46
    • 0035955735 scopus 로고    scopus 로고
    • Protein kinase D potentiates DNA synthesis and cell proliferation induced by bombesin, vasopressin, or phorbol esters in Swiss 3T3 cells
    • Zhukova E., Sinnett-Smith J., Rozengurt E. Protein kinase D potentiates DNA synthesis and cell proliferation induced by bombesin, vasopressin, or phorbol esters in Swiss 3T3 cells. J. Biol. Chem. 2001, 276:40298-40305.
    • (2001) J. Biol. Chem. , vol.276 , pp. 40298-40305
    • Zhukova, E.1    Sinnett-Smith, J.2    Rozengurt, E.3
  • 47
    • 0030771317 scopus 로고    scopus 로고
    • Bombesin, vasopressin, endothelin, bradykinin, and platelet-derived growth factor rapidly activate protein kinase D through a protein kinase C-dependent signal transduction pathway
    • Zugaza J.L., Waldron R.T., Sinnett-Smith J., Rozengurt E. Bombesin, vasopressin, endothelin, bradykinin, and platelet-derived growth factor rapidly activate protein kinase D through a protein kinase C-dependent signal transduction pathway. J. Biol. Chem. 1997, 272:23952-23960.
    • (1997) J. Biol. Chem. , vol.272 , pp. 23952-23960
    • Zugaza, J.L.1    Waldron, R.T.2    Sinnett-Smith, J.3    Rozengurt, E.4


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