메뉴 건너뛰기




Volumn 31, Issue 4, 2012, Pages 972-985

The SNF2-like helicase HELLS mediates E2F3-dependent transcription and cellular transformation

Author keywords

cell cycle re entry; E2F3; H3K27me3; HELLS; prostate tumour

Indexed keywords

HELICASE; PROTEIN; PROTEIN MIXED LINEAGE LEUKAEMIA1; PROTEIN SNF2; TRANSCRIPTION FACTOR E2F3; UNCLASSIFIED DRUG;

EID: 84857048728     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/emboj.2011.451     Document Type: Article
Times cited : (63)

References (48)
  • 1
    • 2942547243 scopus 로고    scopus 로고
    • Repression of the Arf tumor suppressor by E2F3 is required for normal cell cycle kinetics
    • DOI 10.1101/gad.1196704
    • Aslanian A, Iaquinta PJ, Verona R, Lees JA (2004) Repression of the Arf tumor suppressor by E2F3 is required for normal cell cycle kinetics. Genes Dev 18: 1413-1422 (Pubitemid 38780628)
    • (2004) Genes and Development , vol.18 , Issue.12 , pp. 1413-1422
    • Aslanian, A.1    Iaquinta, P.J.2    Verona, R.3    Lees, J.A.4
  • 2
    • 58149510643 scopus 로고    scopus 로고
    • E2f3b plays an essential role in myogenic differentiation through isoform-specific gene regulation
    • Asp P, Acosta-Alvear D, Tsikitis M, van Oevelen C, Dynlacht BD (2009) E2f3b plays an essential role in myogenic differentiation through isoform-specific gene regulation. Genes Dev 23: 37-53
    • (2009) Genes Dev , vol.23 , pp. 37-53
    • Asp, P.1    Acosta-Alvear, D.2    Tsikitis, M.3    Van Oevelen, C.4    Dynlacht, B.D.5
  • 4
    • 36749080303 scopus 로고    scopus 로고
    • E2F-associated chromatin modifiers and cell cycle control
    • DOI 10.1016/j.ceb.2007.10.003, PII S0955067407001408, Cell Differentiation / Cell Division, Growth and Death
    • Blais A, Dynlacht BD (2007) E2F-associated chromatin modifiers and cell cycle control. Curr Opin Cell Biol 19: 658-662 (Pubitemid 350216425)
    • (2007) Current Opinion in Cell Biology , vol.19 , Issue.6 , pp. 658-662
    • Blais, A.1    Dynlacht, B.D.2
  • 5
    • 50149120366 scopus 로고    scopus 로고
    • Cellular mechanisms of tumour suppression by the retinoblastoma gene
    • Burkhart DL, Sage J (2008) Cellular mechanisms of tumour suppression by the retinoblastoma gene. Nat Rev Cancer 8: 671-682
    • (2008) Nat Rev Cancer , vol.8 , pp. 671-682
    • Burkhart, D.L.1    Sage, J.2
  • 8
    • 33750920705 scopus 로고    scopus 로고
    • Distinct and overlapping roles for E2F family members in transcription, proliferation and apoptosis
    • DeGregori J, Johnson DG (2006) Distinct and overlapping roles for E2F family members in transcription, proliferation and apoptosis. Curr Mol Med 6: 739-748 (Pubitemid 44725567)
    • (2006) Current Molecular Medicine , vol.6 , Issue.7 , pp. 739-748
    • DeGregori, J.1    Johnson, D.G.2
  • 9
    • 0035890090 scopus 로고    scopus 로고
    • Lsh, a member of the SNF2 family, is required for genome-wide methylation
    • DOI 10.1101/gad.929101
    • Dennis K, Fan T, Geiman T, Yan Q, Muegge K (2001) Lsh, a member of the SNF2 family, is required for genome-wide methylation. Genes Dev 15: 2940-2944 (Pubitemid 33078944)
    • (2001) Genes and Development , vol.15 , Issue.22 , pp. 2940-2944
    • Dennis, K.1    Fan, T.2    Geiman, T.3    Yan, Q.4    Muegge, K.5
  • 10
    • 0043136702 scopus 로고    scopus 로고
    • Lsh-deficient murine embryonal fibroblasts show reduced proliferation with signs of abnormal mitosis
    • Fan T, Yan Q, Huang J, Austin S, Cho E, Ferris D, Muegge K (2003) Lsh-deficient murine embryonal fibroblasts show reduced proliferation with signs of abnormal mitosis. Cancer Res 63: 4677-4683 (Pubitemid 36951047)
    • (2003) Cancer Research , vol.63 , Issue.15 , pp. 4677-4683
    • Fan, T.1    Yan, Q.2    Huang, J.3    Austin, S.4    Cho, E.5    Ferris, D.6    Muegge, K.7
  • 14
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: The next generation
    • Hanahan D, Weinberg RA (2011) Hallmarks of cancer: the next generation. Cell 144: 646-674
    • (2011) Cell , vol.144 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 17
    • 42549109141 scopus 로고    scopus 로고
    • Inactivation of the Rb pathway and overexpression of both isoforms of E2F3 are obligate events in bladder tumours with 6p22 amplification
    • DOI 10.1038/sj.onc.1210934, PII 1210934
    • Hurst CD, Tomlinson DC, Williams SV, Platt FM, Knowles MA (2008) Inactivation of the Rb pathway and overexpression of both isoforms of E2F3 are obligate events in bladder tumours with 6p22 amplification. Oncogene 27: 2716-2727 (Pubitemid 351581468)
    • (2008) Oncogene , vol.27 , Issue.19 , pp. 2716-2727
    • Hurst, C.D.1    Tomlinson, D.C.2    Williams, S.V.3    Platt, F.M.4    Knowles, M.A.5
  • 18
    • 33846283395 scopus 로고    scopus 로고
    • Compensation and specificity of function within the E2F family
    • DOI 10.1038/sj.onc.1209817, PII 1209817
    • Kong LJ, Chang JT, Bild AH, Nevins JR (2007) Compensation and specificity of function within the E2F family. Oncogene 26: 321-327 (Pubitemid 46122822)
    • (2007) Oncogene , vol.26 , Issue.3 , pp. 321-327
    • Kong, L.-J.1    Chang, J.T.2    Bild, A.H.3    Nevins, J.R.4
  • 19
    • 0035979992 scopus 로고    scopus 로고
    • E2F transcriptional activation requires TRRAP and GCN5 cofactors
    • Lang SE, McMahon SB, Cole MD, Hearing P (2001) E2F transcriptional activation requires TRRAP and GCN5 cofactors. J Biol Chem 276: 32627-32634
    • (2001) J Biol Chem , vol.276 , pp. 32627-32634
    • Lang, S.E.1    McMahon, S.B.2    Cole, M.D.3    Hearing, P.4
  • 20
    • 0034011378 scopus 로고    scopus 로고
    • Identification of a novel E2F3 product suggests a mechanism for determining specificity of repression by Rb proteins
    • DOI 10.1128/MCB.20.10.3626-3632.2000
    • Leone G, Nuckolls F, Ishida S, Adams M, Sears R, Jakoi L, Miron A, Nevins JR (2000) Identification of a novel E2F3 product suggests a mechanism for determining specificity of repression by Rb proteins. Mol Cell Biol 20: 3626-3632 (Pubitemid 30243908)
    • (2000) Molecular and Cellular Biology , vol.20 , Issue.10 , pp. 3626-3632
    • Leone, G.1    Nuckolls, F.2    Ishida, S.3    Adams, M.4    Sears, R.5    Jakoi, L.6    Miron, A.7    Nevins, J.R.8
  • 21
    • 34948839290 scopus 로고    scopus 로고
    • Cdc20 assures cell cycle execution: A critical regulatory circuit lost in leukemogenic MLL fusions
    • DOI 10.1101/gad.1574507
    • Liu H, Cheng EH, Hsieh JJ (2007) Bimodal degradation of MLL by SCFSkp 2 and APCCdc 20 assures cell cycle execution: a critical regulatory circuit lost in leukemogenic MLL fusions. Genes Dev 21: 2385-2398 (Pubitemid 47529369)
    • (2007) Genes and Development , vol.21 , Issue.19 , pp. 2385-2398
    • Liu, H.1    Cheng, E.H.-Y.2    Hsieh, J.J.-D.3
  • 23
    • 0032493894 scopus 로고    scopus 로고
    • The novel ATM-related protein TRRAP is an essential cofactor for the c- Myc and E2F oncoproteins
    • DOI 10.1016/S0092-8674(00)81479-8
    • McMahon SB, Van Buskirk HA, Dugan KA, Copeland TD, Cole MD (1998) The novel ATM-related protein TRRAP is an essential cofactor for the c-Myc and E2F oncoproteins. Cell 94: 363-374 (Pubitemid 28376080)
    • (1998) Cell , vol.94 , Issue.3 , pp. 363-374
    • McMahon, S.B.1    Van Buskirk, H.A.2    Dugan, K.A.3    Copeland, T.D.4    Cole, M.D.5
  • 25
    • 37549061829 scopus 로고    scopus 로고
    • LSH cooperates with DNA methyltransferases to repress transcription
    • Myant K, Stancheva I (2008) LSH cooperates with DNA methyltransferases to repress transcription. Mol Cell Biol 28: 215-226
    • (2008) Mol Cell Biol , vol.28 , pp. 215-226
    • Myant, K.1    Stancheva, I.2
  • 27
    • 0037667702 scopus 로고    scopus 로고
    • Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence
    • DOI 10.1016/S0092-8674(03)00401-X
    • Narita M, Nnez S, Heard E, Narita M, Lin AW, Hearn SA, Spector DL, Hannon GJ, Lowe SW (2003) Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence. Cell 113: 703-716 (Pubitemid 36724935)
    • (2003) Cell , vol.113 , Issue.6 , pp. 703-716
    • Narita, M.1    Nunez, S.2    Heard, E.3    Narita, M.4    Lin, A.W.5    Hearn, S.A.6    Spector, D.L.7    Hannon, G.J.8    Lowe, S.W.9
  • 29
    • 79955786911 scopus 로고    scopus 로고
    • Transcriptional activation of the senescence regulator Lsh by E2F1
    • Niu J, Chen T, Han L, Wang P, Li N, Tong T (2011) Transcriptional activation of the senescence regulator Lsh by E2F1. Mech Ageing Dev 132: 180-186
    • (2011) Mech Ageing Dev , vol.132 , pp. 180-186
    • Niu, J.1    Chen, T.2    Han, L.3    Wang, P.4    Li, N.5    Tong, T.6
  • 30
    • 3342974830 scopus 로고    scopus 로고
    • E2F3 amplification and overexpression is associated with invasive tumor growth and rapid tumor cell proliferation in urinary bladder cancer
    • DOI 10.1038/sj.onc.1207749
    • Oeggerli M, Tomovska S, Schraml P, Calvano-Forte D, Schafroth S, Simon R, Gasser T, Mihatsch MJ, Sauter G (2004) E2F3 amplification and overexpression is associated with invasive tumor growth and rapid tumor cell proliferation in urinary bladder cancer. Oncogene 23: 5616-5623 (Pubitemid 39093039)
    • (2004) Oncogene , vol.23 , Issue.33 , pp. 5616-5623
    • Oeggerli, M.1    Tomovska, S.2    Schraml, P.3    Calvano-Forte, D.4    Schafroth, S.5    Simon, R.6    Gasser, T.7    Mihatsch, M.J.8    Sauter, G.9
  • 31
    • 33947216150 scopus 로고    scopus 로고
    • Selective requirements for E2f3 in the development and tumorigenicity of Rb-deficient chimeric tissues
    • DOI 10.1128/MCB.01854-06
    • Parisi T, Yuan TL, Faust AM, Caron AM, Bronson R, Lees JA (2007) Selective requirements for E2f3 in the development and tumorigenicity of Rb-deficient chimeric tissues. Mol Cell Biol 27: 2283-2293 (Pubitemid 46418482)
    • (2007) Molecular and Cellular Biology , vol.27 , Issue.6 , pp. 2283-2293
    • Parisi, T.1    Yuan, T.L.2    Faust, A.M.3    Caron, A.M.4    Bronson, R.5    Lees, J.A.6
  • 32
    • 0035027772 scopus 로고    scopus 로고
    • An SNF2 factor involved in mammalian development and cellular proliferation
    • Raabe EH, Abdurrahman L, Behbehani G, Arceci RJ (2001) An SNF2 factor involved in mammalian development and cellular proliferation. Dev Dyn 221: 92-105
    • (2001) Dev Dyn , vol.221 , pp. 92-105
    • Raabe, E.H.1    Abdurrahman, L.2    Behbehani, G.3    Arceci, R.J.4
  • 35
    • 0042510099 scopus 로고    scopus 로고
    • Inactivation of E2F3 results in centrosome amplification
    • DOI 10.1016/S1535-6108(03)00083-7, PII S1535610803000837
    • Saavedra HI, Maiti B, Timmers C, Altura R, Tokuyama Y, Fukasawa K, Leone G (2003) Inactivation of E2F3 results in centrosome amplification. Cancer Cell 3: 333-346 (Pubitemid 38340303)
    • (2003) Cancer Cell , vol.3 , Issue.4 , pp. 333-346
    • Saavedra, H.I.1    Maiti, B.2    Timmers, C.3    Altura, R.4    Tokuyama, Y.5    Fukasawa, K.6    Leone, G.7
  • 36
    • 78149485776 scopus 로고    scopus 로고
    • Interpretation of developmental signaling at chromatin: The polycomb perspective
    • Sawarkar R, Paro R (2010) Interpretation of developmental signaling at chromatin: the polycomb perspective. Dev Cell 19: 651-661
    • (2010) Dev Cell , vol.19 , pp. 651-661
    • Sawarkar, R.1    Paro, R.2
  • 37
    • 0344199413 scopus 로고    scopus 로고
    • Functional evidence for a role of combined CDKN2A (p16-p14(ARF))/CDKN2B [p15) gene inactivation in malignant gliomas
    • DOI 10.1007/s004010051107
    • Simon M, Köster G, Menon AG, Schramm J (1999) Functional evidence for a role of combined CDKN2A (p16-p14ARF)/CDKN2B (p15) gene inactivation in malignant gliomas. Acta Neuropatho 98: 444-452 (Pubitemid 29476161)
    • (1999) Acta Neuropathologica , vol.98 , Issue.5 , pp. 444-452
    • Simon, M.1    Koster, G.2    Menon, A.G.3    Schramm, J.4
  • 39
    • 0034175616 scopus 로고    scopus 로고
    • Analysis of promoter binding by the E2F and pRB families in vivo: Distinct E2F proteins mediate activation and repression
    • Takahashi Y, Rayman JB, Dynlacht BD (2000) Analysis of promoter binding by the E2F and pRB families in vivo: distinct E2F proteins mediate activation and repression. Genes Dev 14: 804-816 (Pubitemid 30215000)
    • (2000) Genes and Development , vol.14 , Issue.7 , pp. 804-816
    • Takahashi, Y.1    Rayman, J.B.2    Dynlacht, B.D.3
  • 42
    • 34250823511 scopus 로고    scopus 로고
    • E2F Activation of S Phase Promoters via Association with HCF-1 and the MLL Family of Histone H3K4 Methyltransferases
    • DOI 10.1016/j.molcel.2007.05.030, PII S1097276507003310
    • Tyagi S, Chabes AL, Wysocka J, Herr W (2007) E2F activation of S phase promoters via association with HCF-1 and the MLL family of histone H3K4 methyltransferases. Mol Cell 27: 107-119 (Pubitemid 46991384)
    • (2007) Molecular Cell , vol.27 , Issue.1 , pp. 107-119
    • Tyagi, S.1    Chabes, A.L.2    Wysocka, J.3    Herr, W.4
  • 43
    • 50149108858 scopus 로고    scopus 로고
    • Conserved functions of the pRB and E2F families
    • Van den Heuvel S, Dyson NJ (2008) Conserved functions of the pRB and E2F families. Nat Rev Mol Cell Biol 9: 713-724
    • (2008) Nat Rev Mol Cell Biol , vol.9 , pp. 713-724
    • Van Den Heuvel, S.1    Dyson, N.J.2
  • 44
    • 77953357848 scopus 로고    scopus 로고
    • Downstream targets of FOXM1: CEP55 and HELLS are cancer progression markers of head and neck squamous cell carcinoma
    • Waseem A, Ali M, Odell EW, Fortune F, Teh MT (2010) Downstream targets of FOXM1: CEP55 and HELLS are cancer progression markers of head and neck squamous cell carcinoma. Oral Oncol 46: 536-542
    • (2010) Oral Oncol , vol.46 , pp. 536-542
    • Waseem, A.1    Ali, M.2    Odell, E.W.3    Fortune, F.4    Teh, M.T.5
  • 46
    • 0141628697 scopus 로고    scopus 로고
    • Association of Lsh, a Regulator of DNA Methylation, with Pericentromeric Heterochromatin Is Dependent on Intact Heterochromatin
    • DOI 10.1128/MCB.23.23.8416-8428.2003
    • Yan Q, Cho E, Lockett S, Muegge K (2003) Association of Lsh, a regulator of DNA methylation, with pericentromeric heterochromatin is dependent on intact heterochromatin. Mol Cell Biol 23: 8416-8428 (Pubitemid 37433350)
    • (2003) Molecular and Cellular Biology , vol.23 , Issue.23 , pp. 8416-8428
    • Yan, Q.1    Cho, E.2    Lockett, S.3    Muegge, K.4
  • 48
    • 0042190650 scopus 로고    scopus 로고
    • E2F3 loss has opposing effects on different pRB-deficient tumors, resulting in suppression of pituitary tumors but metastasis of medullary thyroid carcinomas
    • DOI 10.1128/MCB.23.18.6542-6552.2003
    • Ziebold U, Lee EY, Bronson RT, Lees JA (2003) E2F3 loss has opposing effects on different pRB-deficient tumors, resulting in suppression of pituitary tumors but metastasis of medullary thyroid carcinomas. Mol Cell Biol 23: 6542-6552 (Pubitemid 37075765)
    • (2003) Molecular and Cellular Biology , vol.23 , Issue.18 , pp. 6542-6552
    • Ziebold, U.1    Lee, E.Y.2    Bronson, R.T.3    Lees, J.A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.