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Volumn 12, Issue 1, 2012, Pages 101-107

Glycemic targets and approaches to management of the patient with critical illness

Author keywords

Blood glucose management; Critical illness; Glycemic targets; Hyperglycemia; NICE SUGAR; Normoglycemia; Stress hyperglycemia

Indexed keywords

GLUCOSE; HETASTARCH; INSULIN; RINGER LACTATE SOLUTION;

EID: 84857044584     PISSN: 15344827     EISSN: 15390829     Source Type: Journal    
DOI: 10.1007/s11892-011-0241-8     Document Type: Article
Times cited : (39)

References (44)
  • 1
    • 70649088951 scopus 로고    scopus 로고
    • Hyperglycaemia as part of the stress response: The underlying mechanisms
    • 20108577 10.1016/j.bpa.2009.08.005
    • SJ Van Cromphaut 2009 Hyperglycaemia as part of the stress response: the underlying mechanisms Best Pract Res Clin Anaesthesiol 23 4 375 386 20108577 10.1016/j.bpa.2009.08.005
    • (2009) Best Pract Res Clin Anaesthesiol , vol.23 , Issue.4 , pp. 375-386
    • Van Cromphaut, S.J.1
  • 2
    • 64949093742 scopus 로고    scopus 로고
    • Early blood glucose control and mortality in critically ill patients in Australia
    • 19114915 10.1097/CCM.0b013e318194b097 1:CAS:528:DC%2BD1MXjs1Kntbc%3D
    • SM Bagshaw M Egi C George R Bellomo 2009 Early blood glucose control and mortality in critically ill patients in Australia Crit Care Med 37 2 463 470 19114915 10.1097/CCM.0b013e318194b097 1:CAS:528:DC%2BD1MXjs1Kntbc%3D
    • (2009) Crit Care Med , vol.37 , Issue.2 , pp. 463-470
    • Bagshaw, S.M.1    Egi, M.2    George, C.3    Bellomo, R.4
  • 3
    • 20544451806 scopus 로고    scopus 로고
    • Admission glucose and mortality in elderly patients hospitalized with acute myocardial infarction: Implications for patients with and without recognized diabetes
    • DOI 10.1161/CIRCULATIONAHA.104.517839
    • M Kosiborod SS Rathore SE Inzucchi FA Masoudi Y Wang EP Havranek, et al. 2005 Admission glucose and mortality in elderly patients hospitalized with acute myocardial infarction: implications for patients with and without recognized diabetes Circulation 111 23 3078 3086 15939812 10.1161/CIRCULATIONAHA.104.517839 1:CAS:528:DC%2BD2MXkvVCmurY%3D (Pubitemid 40847785)
    • (2005) Circulation , vol.111 , Issue.23 , pp. 3078-3086
    • Kosiborod, M.1    Rathore, S.S.2    Inzucchi, S.E.3    Masoudi, F.A.4    Wang, Y.5    Havranek, E.P.6    Krumholz, H.M.7
  • 4
    • 62449193994 scopus 로고    scopus 로고
    • Glucose normalization and outcomes in patients with acute myocardial infarction
    • 19273773 10.1001/archinternmed.2008.593 1:CAS:528:DC%2BD1MXktVels78%3D
    • M Kosiborod SE Inzucchi HM Krumholz FA Masoudi A Goyal L Xiao, et al. 2009 Glucose normalization and outcomes in patients with acute myocardial infarction Arch Intern Med 169 5 438 446 19273773 10.1001/archinternmed.2008.593 1:CAS:528:DC%2BD1MXktVels78%3D
    • (2009) Arch Intern Med , vol.169 , Issue.5 , pp. 438-446
    • Kosiborod, M.1    Inzucchi, S.E.2    Krumholz, H.M.3    Masoudi, F.A.4    Goyal, A.5    Xiao, L.6
  • 5
    • 41149178494 scopus 로고    scopus 로고
    • Hyperglycemia and acute coronary syndrome: A scientific statement from the american heart association diabetes committee of the council on nutrition, physical activity, and metabolism
    • DOI 10.1161/CIRCULATIONAHA.107.188629, PII 0000301720080325000018
    • P Deedwania M Kosiborod E Barrett A Ceriello W Isley T Mazzone, et al. 2008 Hyperglycemia and acute coronary syndrome: a scientific statement from the American Heart Association Diabetes Committee of the Council on Nutrition, Physical Activity, and Metabolism Circulation 117 12 1610 1619 18299505 10.1161/CIRCULATIONAHA.107.188629 (Pubitemid 351440650)
    • (2008) Circulation , vol.117 , Issue.12 , pp. 1610-1619
    • Deedwania, P.1    Kosiborod, M.2    Barrett, E.3    Ceriello, A.4    Isley, W.5    Mazzone, T.6    Raskin, P.7
  • 6
    • 61449258501 scopus 로고    scopus 로고
    • Association of elevated fasting glucose with increased short-term and 6-month mortality in ST-segment elevation and non-ST-segment elevation acute coronary syndromes: The Global Registry of Acute Coronary Events
    • 19237725 10.1001/archinternmed.2008.572 1:CAS:528:DC%2BD1MXjsVKntr4%3D
    • PR Sinnaeve PG Steg KA Fox F Van de Werf G Montalescot CB Granger, et al. 2009 Association of elevated fasting glucose with increased short-term and 6-month mortality in ST-segment elevation and non-ST-segment elevation acute coronary syndromes: the Global Registry of Acute Coronary Events Arch Intern Med 169 4 402 409 19237725 10.1001/archinternmed.2008.572 1:CAS:528: DC%2BD1MXjsVKntr4%3D
    • (2009) Arch Intern Med , vol.169 , Issue.4 , pp. 402-409
    • Sinnaeve, P.R.1    Steg, P.G.2    Fox, K.A.3    Van De Werf, F.4    Montalescot, G.5    Granger, C.B.6
  • 7
    • 33947546779 scopus 로고    scopus 로고
    • Achieving Tight Glycemic Control in the Operating Room: Lessons Learned from 12 Years in the Trenches of a Paradigm Shift in Anesthetic Care
    • DOI 10.1053/j.semtcvs.2007.01.004, PII S1043067907000093, Diabetes, Hyperglycemia, and Cardiac Surgery Patient
    • AP Furnary DB Cheek SC Holmes WL Howell SP Kelly 2006 Achieving tight glycemic control in the operating room: lessons learned from 12 years in the trenches of a paradigm shift in anesthetic care Semin Thorac Cardiovasc Surg 18 4 339 345 17395031 10.1053/j.semtcvs.2007.01.004 (Pubitemid 46464519)
    • (2006) Seminars in Thoracic and Cardiovascular Surgery , vol.18 , Issue.4 , pp. 339-345
    • Furnary, A.P.1    Cheek, D.B.2    Holmes, S.C.3    Howell, W.L.4    Kelly, S.P.5
  • 9
    • 0033710560 scopus 로고    scopus 로고
    • Hypocaloric total parenteral nutrition: Effectiveness in prevention of hyperglycemia and infectious complications-a randomized clinical trial
    • 11098961 10.1097/00003246-200011000-00007 1:CAS:528:DC%2BD3MXjslyhs7o%3D
    • KC McCowen C Friel J Sternberg S Chan RA Forse PA Burke, et al. 2000 Hypocaloric total parenteral nutrition: effectiveness in prevention of hyperglycemia and infectious complications-a randomized clinical trial Crit Care Med 28 11 3606 3611 11098961 10.1097/00003246-200011000-00007 1:CAS:528:DC%2BD3MXjslyhs7o%3D
    • (2000) Crit Care Med , vol.28 , Issue.11 , pp. 3606-3611
    • McCowen, K.C.1    Friel, C.2    Sternberg, J.3    Chan, S.4    Forse, R.A.5    Burke, P.A.6
  • 11
    • 59749098319 scopus 로고    scopus 로고
    • Intensive insulin therapy for patients in paediatric intensive care: A prospective, randomised controlled study
    • 19176240 10.1016/S0140-6736(09)60044-1 1:CAS:528:DC%2BD1MXhvFGltLs%3D
    • D Vlasselaers I Milants L Desmet PJ Wouters I Vanhorebeek I van den Heuvel, et al. 2009 Intensive insulin therapy for patients in paediatric intensive care: a prospective, randomised controlled study Lancet 373 9663 547 556 19176240 10.1016/S0140-6736(09)60044-1 1:CAS:528:DC%2BD1MXhvFGltLs%3D
    • (2009) Lancet , vol.373 , Issue.9663 , pp. 547-556
    • Vlasselaers, D.1    Milants, I.2    Desmet, L.3    Wouters, P.J.4    Vanhorebeek, I.5    Van Den Heuvel, I.6
  • 12
    • 38049096093 scopus 로고    scopus 로고
    • Intensive insulin therapy and pentastarch resuscitation in severe sepsis
    • 18184958 10.1056/NEJMoa070716 1:CAS:528:DC%2BD1cXltFWltQ%3D%3D
    • FM Brunkhorst C Engel F Bloos A Meier-Hellmann M Ragaller N Weiler, et al. 2008 Intensive insulin therapy and pentastarch resuscitation in severe sepsis N Engl J Med 358 2 125 139 18184958 10.1056/NEJMoa070716 1:CAS:528:DC%2BD1cXltFWltQ%3D%3D
    • (2008) N Engl J Med , vol.358 , Issue.2 , pp. 125-139
    • Brunkhorst, F.M.1    Engel, C.2    Bloos, F.3    Meier-Hellmann, A.4    Ragaller, M.5    Weiler, N.6
  • 13
    • 72249083789 scopus 로고    scopus 로고
    • A prospective randomised multi-centre controlled trial on tight glucose control by intensive insulin therapy in adult intensive care units: The Glucontrol study
    • 19636533 10.1007/s00134-009-1585-2 1:CAS:528:DC%2BD1MXhtFOiu7fE
    • JC Preiser P Devos S Ruiz-Santana C Melot D Annane J Groeneveld, et al. 2009 A prospective randomised multi-centre controlled trial on tight glucose control by intensive insulin therapy in adult intensive care units: the Glucontrol study Intensive Care Med 35 10 1738 1748 19636533 10.1007/s00134-009-1585-2 1:CAS:528:DC%2BD1MXhtFOiu7fE
    • (2009) Intensive Care Med , vol.35 , Issue.10 , pp. 1738-1748
    • Preiser, J.C.1    Devos, P.2    Ruiz-Santana, S.3    Melot, C.4    Annane, D.5    Groeneveld, J.6
  • 14
    • 63249128249 scopus 로고    scopus 로고
    • Intensive versus conventional glucose control in critically ill patients
    • 19318384 10.1056/NEJMoa0810625 This large pragmatic multicenter trial showed that tight blood glucose control, when implemented under less controlled circumstance, increased mortality
    • S Finfer DR Chittock SY Su D Blair D Foster V Dhingra, et al. 2009 Intensive versus conventional glucose control in critically ill patients N Engl J Med 360 13 1283 1297 19318384 10.1056/NEJMoa0810625 This large pragmatic multicenter trial showed that tight blood glucose control, when implemented under less controlled circumstance, increased mortality
    • (2009) N Engl J Med , vol.360 , Issue.13 , pp. 1283-1297
    • Finfer, S.1    Chittock, D.R.2    Su, S.Y.3    Blair, D.4    Foster, D.5    Dhingra, V.6
  • 15
    • 69949107080 scopus 로고    scopus 로고
    • Clinical review: Intensive insulin therapy in critically ill patients: NICE-SUGAR or Leuven blood glucose target?
    • 19531590 10.1210/jc.2009-0663 This article provides possible explanations why the benefits of the Leuven tight blood glucose control could not be confirmed in the repeat studies
    • G Van den Berghe M Schetz D Vlasselaers G Hermans A Wilmer R Bouillon, et al. 2009 Clinical review: intensive insulin therapy in critically ill patients: NICE-SUGAR or Leuven blood glucose target? J Clin Endocrinol Metab 94 9 3163 3170 19531590 10.1210/jc.2009-0663 This article provides possible explanations why the benefits of the Leuven tight blood glucose control could not be confirmed in the repeat studies
    • (2009) J Clin Endocrinol Metab , vol.94 , Issue.9 , pp. 3163-3170
    • Van Den Berghe, G.1    Schetz, M.2    Vlasselaers, D.3    Hermans, G.4    Wilmer, A.5    Bouillon, R.6
  • 16
    • 65349101684 scopus 로고    scopus 로고
    • Intensive insulin therapy in the intensive care unit
    • 19318386 10.1503/cmaj.090500
    • G Van den Berghe D Mesotten I Vanhorebeek 2009 Intensive insulin therapy in the intensive care unit CMAJ 180 8 799 800 19318386 10.1503/cmaj.090500
    • (2009) CMAJ , vol.180 , Issue.8 , pp. 799-800
    • Van Den Berghe, G.1    Mesotten, D.2    Vanhorebeek, I.3
  • 17
    • 33646893271 scopus 로고    scopus 로고
    • Management of blood glucose in the critically ill in Australia and New Zealand: A practice survey and inception cohort study
    • DOI 10.1007/s00134-006-0135-4
    • I Mitchell S Finfer R Bellomo T Higlett 2006 Management of blood glucose in the critically ill in Australia and New Zealand: a practice survey and inception cohort study Intensive Care Med 32 6 867 874 16622639 10.1007/s00134-006-0135-4 (Pubitemid 43781368)
    • (2006) Intensive Care Medicine , vol.32 , Issue.6 , pp. 867-874
    • Mitchell, I.1    Finfer, S.2    Bellomo, R.3    Higlett, T.4
  • 19
    • 65349096195 scopus 로고    scopus 로고
    • Intensive insulin therapy and mortality among critically ill patients: A meta-analysis including NICE-SUGAR study data
    • 10.1503/cmaj.090206
    • DEG Griesdale RJ de Souza RM van Dam DK Heyland DJ Cook A Malhotra, et al. 2009 Intensive insulin therapy and mortality among critically ill patients: a meta-analysis including NICE-SUGAR study data Can Med Assoc J 180 8 821 827 10.1503/cmaj.090206
    • (2009) Can Med Assoc J , vol.180 , Issue.8 , pp. 821-827
    • Griesdale, D.E.G.1    De Souza, R.J.2    Van Dam, R.M.3    Heyland, D.K.4    Cook, D.J.5    Malhotra, A.6
  • 20
    • 79960435703 scopus 로고    scopus 로고
    • Glycemic control in the ICU
    • 21729892 10.1378/chest.10-1478
    • M Egi S Finfer R Bellomo 2011 Glycemic control in the ICU Chest 140 1 212 220 21729892 10.1378/chest.10-1478
    • (2011) Chest , vol.140 , Issue.1 , pp. 212-220
    • Egi, M.1    Finfer, S.2    Bellomo, R.3
  • 21
    • 58149231157 scopus 로고    scopus 로고
    • Tight glucose control in the intensive care unit: Are glucose meters up to the task?
    • 19028817 10.1373/clinchem.2008.117291 1:CAS:528:DC%2BD1MXptFartQ%3D%3D
    • MG Scott DE Bruns JC Boyd DB Sacks 2009 Tight glucose control in the intensive care unit: are glucose meters up to the task? Clin Chem 55 1 18 20 19028817 10.1373/clinchem.2008.117291 1:CAS:528:DC%2BD1MXptFartQ%3D%3D
    • (2009) Clin Chem , vol.55 , Issue.1 , pp. 18-20
    • Scott, M.G.1    Bruns, D.E.2    Boyd, J.C.3    Sacks, D.B.4
  • 22
    • 79952996013 scopus 로고    scopus 로고
    • Estimates of total analytical error in consumer and hospital glucose meters contributed by hematocrit, maltose, and ascorbate
    • 21129345
    • ME Lyon JA DuBois GH Fick AW Lyon 2010 Estimates of total analytical error in consumer and hospital glucose meters contributed by hematocrit, maltose, and ascorbate J Diabetes Sci Technol 4 6 1479 1494 21129345
    • (2010) J Diabetes Sci Technol , vol.4 , Issue.6 , pp. 1479-1494
    • Lyon, M.E.1    Dubois, J.A.2    Fick, G.H.3    Lyon, A.W.4
  • 23
    • 67650498444 scopus 로고    scopus 로고
    • Hematocrit causes the most significant error in point of care glucometers
    • 19318857 10.1097/CCM.0b013e31819d2e8a
    • EA Mann HF Pidcoke J Salinas SE Wolf CE Wade JB Holcomb 2009 Hematocrit causes the most significant error in point of care glucometers Crit Care Med 37 4 1530 19318857 10.1097/CCM.0b013e31819d2e8a
    • (2009) Crit Care Med , vol.37 , Issue.4 , pp. 1530
    • Mann, E.A.1    Pidcoke, H.F.2    Salinas, J.3    Wolf, S.E.4    Wade, C.E.5    Holcomb, J.B.6
  • 24
    • 0343360868 scopus 로고    scopus 로고
    • A multicenter, randomized, controlled clinical trial of transfusion requirements in critical care
    • DOI 10.1056/NEJM199902113400601
    • PC Hebert G Wells MA Blajchman J Marshall C Martin G Pagliarello, et al. 1999 A multicenter, randomized, controlled clinical trial of transfusion requirements in critical care. Transfusion Requirements in Critical Care Investigators, Canadian Critical Care Trials Group N Engl J Med 340 6 409 417 9971864 10.1056/NEJM199902113400601 1:STN:280:DyaK1M7it1Khsg%3D%3D (Pubitemid 29084771)
    • (1999) New England Journal of Medicine , vol.340 , Issue.6 , pp. 409-417
    • Hebert, P.C.1    Wells, G.2    Blajchman, M.A.3    Marshall, J.4    Martin, C.5    Pagliarello, G.6    Tweeddale, M.7    Schweitzer, I.8    Yetisir, E.9
  • 25
    • 67649510400 scopus 로고    scopus 로고
    • Randomized, double-blind, placebo-controlled trial of effects of enteral iron supplementation on anemia and risk of infection during surgical critical illness
    • 10.1089/sur.2008.043
    • FM Pieracci P Henderson JR Rodney DN Holena A Genisca I Ip, et al. 2009 Randomized, double-blind, placebo-controlled trial of effects of enteral iron supplementation on anemia and risk of infection during surgical critical illness Surg Infect (Larchmt) 10 1 9 19 10.1089/sur.2008.043
    • (2009) Surg Infect (Larchmt) , vol.10 , Issue.1 , pp. 9-19
    • Pieracci, F.M.1    Henderson, P.2    Rodney, J.R.3    Holena, D.N.4    Genisca, A.5    Ip, I.6
  • 26
    • 77957299870 scopus 로고    scopus 로고
    • Glycemic control in the burn intensive care unit: Focus on the role of anemia in glucose measurement
    • 20144386
    • EA Mann AG Mora HF Pidcoke SE Wolf CE Wade 2009 Glycemic control in the burn intensive care unit: focus on the role of anemia in glucose measurement J Diabetes Sci Technol 3 6 1319 1329 20144386
    • (2009) J Diabetes Sci Technol , vol.3 , Issue.6 , pp. 1319-1329
    • Mann, E.A.1    Mora, A.G.2    Pidcoke, H.F.3    Wolf, S.E.4    Wade, C.E.5
  • 27
    • 74949117489 scopus 로고    scopus 로고
    • Anemia causes hypoglycemia in intensive care unit patients due to error in single-channel glucometers: Methods of reducing patient risk
    • 19789438 10.1097/CCM.0b013e3181bc826f Anemia causes a systematic error in blood glucose measurements, which may result in hypoglycemia
    • HF Pidcoke CE Wade EA Mann J Salinas BM Cohee JB Holcomb, et al. 2010 Anemia causes hypoglycemia in intensive care unit patients due to error in single-channel glucometers: methods of reducing patient risk Crit Care Med 38 2 471 476 19789438 10.1097/CCM.0b013e3181bc826f Anemia causes a systematic error in blood glucose measurements, which may result in hypoglycemia
    • (2010) Crit Care Med , vol.38 , Issue.2 , pp. 471-476
    • Pidcoke, H.F.1    Wade, C.E.2    Mann, E.A.3    Salinas, J.4    Cohee, B.M.5    Holcomb, J.B.6
  • 29
    • 77954354586 scopus 로고    scopus 로고
    • Could susceptibility to low hematocrit interference have compromised the results of the NICE-SUGAR trial?
    • 20431051 10.1373/clinchem.2010.146217 1:CAS:528:DC%2BC3cXptVentLw%3D
    • GS Cembrowski DV Tran L Slater-Maclean D Chin RT Gibney M Jacka 2010 Could susceptibility to low hematocrit interference have compromised the results of the NICE-SUGAR trial? Clin Chem 56 7 1193 1195 20431051 10.1373/clinchem. 2010.146217 1:CAS:528:DC%2BC3cXptVentLw%3D
    • (2010) Clin Chem , vol.56 , Issue.7 , pp. 1193-1195
    • Cembrowski, G.S.1    Tran, D.V.2    Slater-Maclean, L.3    Chin, D.4    Gibney, R.T.5    Jacka, M.6
  • 30
    • 77953148918 scopus 로고    scopus 로고
    • Glucose meter performance criteria for tight glycemic control estimated by simulation modeling
    • 20511447 10.1373/clinchem.2010.145367 1:CAS:528:DC%2BC3cXptVentrY%3D
    • BS Karon JC Boyd GG Klee 2010 Glucose meter performance criteria for tight glycemic control estimated by simulation modeling Clin Chem 56 7 1091 1097 20511447 10.1373/clinchem.2010.145367 1:CAS:528:DC%2BC3cXptVentrY%3D
    • (2010) Clin Chem , vol.56 , Issue.7 , pp. 1091-1097
    • Karon, B.S.1    Boyd, J.C.2    Klee, G.G.3
  • 31
    • 0028262386 scopus 로고
    • Use of arterial blood with bedside glucose reflectance meters in an intensive care unit: Are they accurate?
    • RE Maser MA Butler GS DeCherney 1994 Use of arterial blood with bedside glucose reflectance meters in an intensive care unit: are they accurate? Crit Care Med 22 4 595 599 8143469 10.1097/00003246-199404000-00014 1:STN:280:DyaK2c7pt1emtw%3D%3D (Pubitemid 24121559)
    • (1994) Critical Care Medicine , vol.22 , Issue.4 , pp. 595-599
    • Maser, R.E.1    Butler, M.A.2    DeCherney, G.S.3
  • 32
    • 55349134410 scopus 로고    scopus 로고
    • Glycemic variability: A strong independent predictor of mortality in critically ill patients
    • 18824908 10.1097/CCM.0b013e31818b38d2 1:CAS:528:DC%2BD1cXht1KmtbnF
    • JS Krinsley 2008 Glycemic variability: a strong independent predictor of mortality in critically ill patients Crit Care Med 36 11 3008 3013 18824908 10.1097/CCM.0b013e31818b38d2 1:CAS:528:DC%2BD1cXht1KmtbnF
    • (2008) Crit Care Med , vol.36 , Issue.11 , pp. 3008-3013
    • Krinsley, J.S.1
  • 33
    • 18144415490 scopus 로고    scopus 로고
    • Should minimal blood glucose variability become the gold standard of glycemic control?
    • DOI 10.1016/j.jdiacomp.2004.10.001
    • IB Hirsch M Brownlee 2005 Should minimal blood glucose variability become the gold standard of glycemic control? J Diabetes Complications 19 3 178 181 15866065 10.1016/j.jdiacomp.2004.10.001 (Pubitemid 40615551)
    • (2005) Journal of Diabetes and its Complications , vol.19 , Issue.3 , pp. 178-181
    • Hirsch, I.B.1    Brownlee, M.2
  • 34
    • 77949499927 scopus 로고    scopus 로고
    • Toward understanding tight glycemic control in the ICU: A systematic review and metaanalysis
    • 20018803 10.1378/chest.09-1737 1:CAS:528:DC%2BC3cXksVyku78%3D
    • PE Marik JC Preiser 2010 Toward understanding tight glycemic control in the ICU: a systematic review and metaanalysis Chest 137 3 544 551 20018803 10.1378/chest.09-1737 1:CAS:528:DC%2BC3cXksVyku78%3D
    • (2010) Chest , vol.137 , Issue.3 , pp. 544-551
    • Marik, P.E.1    Preiser, J.C.2
  • 35
    • 80051648934 scopus 로고    scopus 로고
    • Early versus late parenteral nutrition in critically Ill adults
    • 21714640 10.1056/NEJMoa1102662 1:CAS:528:DC%2BC3MXhtVars7nM This RCT showed that postponing initiation of parenteral nutrition in ICU patients to beyond the first week (late parenteral nutrition) enhanced recovery compared with "early parenteral nutrition."
    • MP Casaer D Mesotten G Hermans PJ Wouters M Schetz G Meyfroidt, et al. 2011 Early versus late parenteral nutrition in critically Ill adults N Engl J Med 365 6 506 517 21714640 10.1056/NEJMoa1102662 1:CAS:528:DC%2BC3MXhtVars7nM This RCT showed that postponing initiation of parenteral nutrition in ICU patients to beyond the first week (late parenteral nutrition) enhanced recovery compared with "early parenteral nutrition."
    • (2011) N Engl J Med , vol.365 , Issue.6 , pp. 506-517
    • Casaer, M.P.1    Mesotten, D.2    Hermans, G.3    Wouters, P.J.4    Schetz, M.5    Meyfroidt, G.6
  • 36
    • 79953875974 scopus 로고    scopus 로고
    • Insufficient activation of autophagy allows cellular damage to accumulate in critically ill patients
    • 21270330 10.1210/jc.2010-2563 1:CAS:528:DC%2BC3MXltF2qu70%3D
    • I Vanhorebeek J Gunst S Derde I Derese M Boussemaere F Guiza, et al. 2011 Insufficient activation of autophagy allows cellular damage to accumulate in critically ill patients J Clin Endocrinol Metab 96 4 E633 E645 21270330 10.1210/jc.2010-2563 1:CAS:528:DC%2BC3MXltF2qu70%3D
    • (2011) J Clin Endocrinol Metab , vol.96 , Issue.4
    • Vanhorebeek, I.1    Gunst, J.2    Derde, S.3    Derese, I.4    Boussemaere, M.5    Guiza, F.6
  • 37
    • 78649704325 scopus 로고    scopus 로고
    • Autophagy and metabolism
    • 21127245 10.1126/science.1193497 1:CAS:528:DC%2BC3cXhsVyrsbbE
    • JD Rabinowitz E White 2010 Autophagy and metabolism Science 330 6009 1344 1348 21127245 10.1126/science.1193497 1:CAS:528:DC%2BC3cXhsVyrsbbE
    • (2010) Science , vol.330 , Issue.6009 , pp. 1344-1348
    • Rabinowitz, J.D.1    White, E.2
  • 38
    • 37649005234 scopus 로고    scopus 로고
    • Autophagy in the pathogenesis of disease
    • 18191218 10.1016/j.cell.2007.12.018 1:CAS:528:DC%2BD1cXhtFehtb8%3D
    • B Levine G Kroemer 2008 Autophagy in the pathogenesis of disease Cell 132 1 27 42 18191218 10.1016/j.cell.2007.12.018 1:CAS:528:DC%2BD1cXhtFehtb8%3D
    • (2008) Cell , vol.132 , Issue.1 , pp. 27-42
    • Levine, B.1    Kroemer, G.2
  • 40
    • 69349090491 scopus 로고    scopus 로고
    • Hypoglycemia with intensive insulin therapy in critically ill patients: Predisposing factors and association with mortality
    • 19623047 10.1097/CCM.0b013e3181a381ad 1:CAS:528:DC%2BD1MXhtVSitrjJ
    • YM Arabi HM Tamim AH Rishu 2009 Hypoglycemia with intensive insulin therapy in critically ill patients: predisposing factors and association with mortality Crit Care Med 37 9 2536 2544 19623047 10.1097/CCM.0b013e3181a381ad 1:CAS:528:DC%2BD1MXhtVSitrjJ
    • (2009) Crit Care Med , vol.37 , Issue.9 , pp. 2536-2544
    • Arabi, Y.M.1    Tamim, H.M.2    Rishu, A.H.3
  • 41
    • 77649215841 scopus 로고    scopus 로고
    • Hypoglycemia and outcome in critically ill patients
    • 20176928 10.4065/mcp.2009.0394
    • M Egi R Bellomo E Stachowski CJ French GK Hart G Taori, et al. 2010 Hypoglycemia and outcome in critically ill patients Mayo Clin Proc 85 3 217 224 20176928 10.4065/mcp.2009.0394
    • (2010) Mayo Clin Proc , vol.85 , Issue.3 , pp. 217-224
    • Egi, M.1    Bellomo, R.2    Stachowski, E.3    French, C.J.4    Hart, G.K.5    Taori, G.6
  • 43
    • 77957790024 scopus 로고    scopus 로고
    • Glucose dysregulation and neurological injury biomarkers in critically ill children
    • 20668035 10.1210/jc.2010-0805 1:CAS:528:DC%2BC3cXhtlCktLvF
    • I Vanhorebeek M Gielen M Boussemaere PJ Wouters FG Grandas D Mesotten, et al. 2010 Glucose dysregulation and neurological injury biomarkers in critically ill children J Clin Endocrinol Metab 95 10 4669 4679 20668035 10.1210/jc.2010-0805 1:CAS:528:DC%2BC3cXhtlCktLvF
    • (2010) J Clin Endocrinol Metab , vol.95 , Issue.10 , pp. 4669-4679
    • Vanhorebeek, I.1    Gielen, M.2    Boussemaere, M.3    Wouters, P.J.4    Grandas, F.G.5    Mesotten, D.6
  • 44
    • 79961228237 scopus 로고    scopus 로고
    • Effect of intensive insulin therapy on the somatotropic axis of critically ill children
    • 21632816 10.1210/jc.2010-3045 1:CAS:528:DC%2BC3MXhtVKhsb%2FN
    • M Gielen D Mesotten M Brugts W Coopmans E Van Herck I Vanhorebeek, et al. 2011 Effect of intensive insulin therapy on the somatotropic axis of critically ill children J Clin Endocrinol Metab 96 8 2558 2566 21632816 10.1210/jc.2010-3045 1:CAS:528:DC%2BC3MXhtVKhsb%2FN
    • (2011) J Clin Endocrinol Metab , vol.96 , Issue.8 , pp. 2558-2566
    • Gielen, M.1    Mesotten, D.2    Brugts, M.3    Coopmans, W.4    Van Herck, E.5    Vanhorebeek, I.6


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