Differences in mtDNA whole sequence between Tibetan and Han populations suggesting adaptive selection to high altitude

Gene

Volumn 496, Issue 1, 2012, Pages 37-44

  Gu, Mingliang ^a,b,c   Dong, Xiaoqun ^d   Shi, Li ^a   Shi, Lei ^a   Lin, Keqin ^a   Huang, Xiaoqin ^a   Chu, Jiayou ^a  

^a INSTITUTE OF MEDICAL BIOLOGY   (China)

^b Chinese Academy of Sciences and China National Center for Bioinformation   (China)

^c INSTITUTE OF GEOLOGY AND GEOPHYSICS   (China)

^d UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

Haplogroup classification; Mitochondrial genome; Nonsynonymous (NS) versus synonymous (S); Principal component analysis; Structure simulation; Tibetan

Indexed keywords

ATP6 PROTEIN; ATP8 PROTEIN; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; CYCLOOXYGENASE 3; CYT B PROTEIN; MITOCHONDRIAL DNA; ND1 PROTEIN; ND2 PROTEIN; ND3 PROTEIN; ND4 PROTEIN; ND5 PROTEIN; ND6 PROTEIN; UNCLASSIFIED DRUG;

ALTITUDE; ARTICLE; CONTROLLED STUDY; DNA EXTRACTION; DNA SEQUENCE; GENETIC DIFFERENCE; GENETIC VARIABILITY; HUMAN; HUMAN CELL; HYDROPHILICITY; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; QUALITY CONTROL;

ADAPTATION, PHYSIOLOGICAL; ALTITUDE; ASIAN CONTINENTAL ANCESTRY GROUP; CELL LINE, TRANSFORMED; CHINA; DNA, MITOCHONDRIAL; GENETICS, POPULATION; GENOME, MITOCHONDRIAL; HUMANS; MODELS, MOLECULAR; PRINCIPAL COMPONENT ANALYSIS; SELECTION, GENETIC; SEQUENCE ANALYSIS, DNA; TIBET;

EID: 84857043377     PISSN: 03781119     EISSN: 18790038     Source Type: Journal    
DOI: 10.1016/j.gene.2011.12.016     Document Type: Article

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