메뉴 건너뛰기




Volumn 15, Issue 2, 2012, Pages 151-160

The impact of premorbid diabetic status on the relationship between the three domains of glycemic control and mortality in critically ill patients

Author keywords

diabetes; glycemic variability; hyperglycemia; hypoglycemia; intensive care; mortality

Indexed keywords

INSULIN;

EID: 84857038560     PISSN: 13631950     EISSN: 14736519     Source Type: Journal    
DOI: 10.1097/MCO.0b013e32834f0009     Document Type: Review
Times cited : (77)

References (53)
  • 1
    • 0035829852 scopus 로고    scopus 로고
    • Intensive insulin therapy in critically ill patients
    • van den Berghe G, Wouters P, Weekers F, et al. Intensive insulin therapy in critically ill patients. N Engl J Med 2001; 345:1359-1367.
    • (2001) N Engl J Med , vol.345 , pp. 1359-1367
    • Van Den Berghe, G.1    Wouters, P.2    Weekers, F.3
  • 3
    • 72249083789 scopus 로고    scopus 로고
    • A prospective randomized multicentre controlled trial on tight glucose control by intensive insulin therapy in adult intensive care units: The Glucontrol study
    • Preiser JC, Devos P, Ruiz-Santana S, et al. A prospective randomized multicentre controlled trial on tight glucose control by intensive insulin therapy in adult intensive care units: The Glucontrol study. Int Care Med 2009; 35:1738-1748.
    • (2009) Int Care Med , vol.35 , pp. 1738-1748
    • Preiser, J.C.1    Devos, P.2    Ruiz-Santana, S.3
  • 4
    • 38049096093 scopus 로고    scopus 로고
    • Intensive insulin therapy and pentastarch resuscitation in severe sepsis
    • Brunkhorst F, Engel C, Bloos F, et al. Intensive insulin therapy and pentastarch resuscitation in severe sepsis. N Eng J Med 2009; 358:125-139.
    • (2009) N Eng J Med , vol.358 , pp. 125-139
    • Brunkhorst, F.1    Engel, C.2    Bloos, F.3
  • 5
    • 58149241371 scopus 로고    scopus 로고
    • Intensive versus conventional insulin therapy: A randomized controlled trial in medical and surgical critically ill patients
    • Arabi Y, Ousama D, Hani T, et al. Intensive versus conventional insulin therapy: A randomized controlled trial in medical and surgical critically ill patients. Crit Care Med 2008; 36:3190-3197.
    • (2008) Crit Care Med , vol.36 , pp. 3190-3197
    • Arabi, Y.1    Ousama, D.2    Hani, T.3
  • 6
    • 63249128249 scopus 로고    scopus 로고
    • The NICE-SUGAR study investigators Intensive versus conventional glucose control in critically ill patients
    • The NICE-SUGAR study investigators. Intensive versus conventional glucose control in critically ill patients. N Engl J Med 2009; 360:1283-1297.
    • (2009) N Engl J Med , vol.360 , pp. 1283-1297
  • 7
    • 69949107080 scopus 로고    scopus 로고
    • Intensive insulin therapy in critically ill patients NICE-SUGAR or Leuven blood glucose target?
    • Van den Berghe G, Schetz M, Vlasselaers D, et al. Intensive insulin therapy in critically ill patients: NICE-SUGAR or Leuven blood glucose target? J Clin Endo Metab 2009; 94:3163-3170.
    • (2009) J Clin Endo Metab , vol.94 , pp. 3163-3170
    • Van Den Berghe, G.1    Schetz, M.2    Vlasselaers, D.3
  • 9
    • 34447622128 scopus 로고    scopus 로고
    • Accuracy and feasibility of point-of-care and continuous blood glucose analysis in critically ill ICU patients
    • Corstjens AM, Lightenberg JJ, van der Horst IC, et al. Accuracy and feasibility of point-of-care and continuous blood glucose analysis in critically ill ICU patients. Crit Care 2006; R135.
    • (2006) Crit Care
    • Corstjens, A.M.1    Lightenberg, J.J.2    Van Der Horst, I.C.3
  • 11
    • 34447506735 scopus 로고    scopus 로고
    • Severe hypoglycemia in critically ill patients: Risk factors and outcomes
    • DOI 10.1097/01.CCM.0000282073.98414.4B, PII 0000324620071000000004
    • Krinsley JS, Grover A. Severe hypoglycemia in critically ill patients: Risk factors and outcomes. Crit Care Med 2007; 35:2262-2267. (Pubitemid 47476221)
    • (2007) Critical Care Medicine , vol.35 , Issue.10 , pp. 2262-2267
    • Krinsley, J.S.1    Grover, A.2
  • 12
    • 64949093742 scopus 로고    scopus 로고
    • Early blood glucose control and mortality in critically ill patients in Australia
    • Bagshaw S, Egi M, George C, Bellomo R. Early blood glucose control and mortality in critically ill patients in Australia. Crit Care Med 2009; 37:463-470.
    • (2009) Crit Care Med , vol.37 , pp. 463-470
    • Bagshaw, S.1    Egi, M.2    George, C.3    Bellomo, R.4
  • 13
    • 77953081942 scopus 로고    scopus 로고
    • Hypoglycemia is associated with intensive care unit mortality
    • Hermanides J, Bosman RJ, Vriesendorp TM. Hypoglycemia is associated with intensive care unit mortality. Crit Care Med 2010; 38:1430-1434.
    • (2010) Crit Care Med , vol.38 , pp. 1430-1434
    • Hermanides, J.1    Bosman, R.J.2    Vriesendorp, T.M.3
  • 14
    • 77649215841 scopus 로고    scopus 로고
    • Hypoglycemia and outcome in critically ill patients
    • This observational cohort study from two ICUs demonstrated that mild hypoglycemia was independently associated with mortality
    • Egi M, Bellomo R, Stachowski E, et al. Hypoglycemia and outcome in critically ill patients. Mayo Clinic Proc 2010; 85:217-224. This observational cohort study from two ICUs demonstrated that mild hypoglycemia was independently associated with mortality.
    • (2010) Mayo Clinic Proc , vol.85 , pp. 217-224
    • Egi, M.1    Bellomo, R.2    Stachowski, E.3
  • 15
    • 79960605274 scopus 로고    scopus 로고
    • Mild hypoglycemia is independently associated with increased mortality in the critically ill
    • This international multicenter study, including observational as well as interventional trial data, confirmed the independent association of mild hypoglycemia, defined as blood glucose less than 70 mg/dl, with mortality in heterogeneous populations of critically ill patients
    • Krinsley JS, Schultz MJ, Spronk PE, et al. Mild hypoglycemia is independently associated with increased mortality in the critically ill. Crit Care 2011; 15:R173. This international multicenter study, including observational as well as interventional trial data, confirmed the independent association of mild hypoglycemia, defined as blood glucose less than 70 mg/dl, with mortality in heterogeneous populations of critically ill patients.
    • (2011) Crit Care , vol.15
    • Krinsley, J.S.1    Schultz, M.J.2    Spronk, P.E.3
  • 16
    • 33746621650 scopus 로고    scopus 로고
    • Variability of blood glucose concentration and short-term mortality in critically ill patients
    • DOI 10.1097/00000542-200608000-00006, PII 0000054220060800000006
    • Egi M, Bellomo R, Stachowski E, et al. Variability of blood glucose concentration and short-term mortality in critically ill patients. Anesthesiology 2006; 105:244-252. (Pubitemid 44148168)
    • (2006) Anesthesiology , vol.105 , Issue.2 , pp. 244-252
    • Egi, M.1    Bellomo, R.2    Stachowski, E.3    French, C.J.4    Hart, G.5
  • 17
    • 55349134410 scopus 로고    scopus 로고
    • Glycemic variability: A strong, independent risk factor for mortality in critically ill patients
    • Krinsley JS. Glycemic variability: A strong, independent risk factor for mortality in critically ill patients. Crit Care Med 2008; 36:3008-3013.
    • (2008) Crit Care Med , vol.36 , pp. 3008-3013
    • Krinsley, J.S.1
  • 18
    • 67650689607 scopus 로고    scopus 로고
    • The impact of early hypoglycemia and blood glucose variability on outcome in critical illness
    • Bagshaw SM, Bellomo R, Jacka MJ, et al. The impact of early hypoglycemia and blood glucose variability on outcome in critical illness. Crit Care 2009; 13:R91.
    • (2009) Crit Care , vol.13
    • Bagshaw, S.M.1    Bellomo, R.2    Jacka, M.J.3
  • 19
    • 77950253961 scopus 로고    scopus 로고
    • Glycemic variability and mortality in critically ill patients: The impact of diabetes
    • Krinsley JS. Glycemic variability and mortality in critically ill patients: The impact of diabetes. J Diab Sci Tech 2009; 3:1292-1301.
    • (2009) J Diab Sci Tech , vol.3 , pp. 1292-1301
    • Krinsley, J.S.1
  • 20
    • 77950264850 scopus 로고    scopus 로고
    • Dynamic characteristics of blood glucose time series during the course of critical illness: Effects of intensive insulin therapy and relative association with mortality
    • Pooled data from the surgical ICU and medical ICU trials of IIT performed in Leuven, Belgium, demonstrated that hypoglycemia as well as increased glycemic variability was independently associated with increased risk of mortality
    • Meyfroidt G, Keenan DM, Wang X, et al. Dynamic characteristics of blood glucose time series during the course of critical illness: Effects of intensive insulin therapy and relative association with mortality. Crit Care Med 2010; 38:1021-1029. Pooled data from the surgical ICU and medical ICU trials of IIT performed in Leuven, Belgium, demonstrated that hypoglycemia as well as increased glycemic variability was independently associated with increased risk of mortality.
    • (2010) Crit Care Med , vol.38 , pp. 1021-1029
    • Meyfroidt, G.1    Keenan, D.M.2    Wang, X.3
  • 21
    • 77249148309 scopus 로고    scopus 로고
    • Glucose variability is associated with intensive care unit mortality
    • Hermanides J, Vriesendorp T, Bosman R, et al. Glucose variability is associated with intensive care unit mortality. Crit Care Med 2010; 38:838-842.
    • (2010) Crit Care Med , vol.38 , pp. 838-842
    • Hermanides, J.1    Vriesendorp, T.2    Bosman, R.3
  • 22
    • 79953806561 scopus 로고    scopus 로고
    • The metrics of glycaemic control in critical care
    • This observational cohort study from several ICUs in a single academic institution demonstrated that hyperglycemia, hypoglycemia and increased glycemic variability had a cumulative association with increased risk of mortality
    • Mackenzie I, Whitehouse T, Nightingale P. The metrics of glycaemic control in critical care. Int Care Med 2011; 37:435-443. This observational cohort study from several ICUs in a single academic institution demonstrated that hyperglycemia, hypoglycemia and increased glycemic variability had a cumulative association with increased risk of mortality.
    • (2011) Int Care Med , vol.37 , pp. 435-443
    • Mackenzie, I.1    Whitehouse, T.2    Nightingale, P.3
  • 23
    • 79953809765 scopus 로고    scopus 로고
    • Understanding glycemic control in the critically ill: Three domains are better than one
    • Krinsley JS. Understanding glycemic control in the critically ill: Three domains are better than one. Int Care Med 2011; 37:382-384.
    • (2011) Int Care Med , vol.37 , pp. 382-384
    • Krinsley, J.S.1
  • 24
    • 28544447013 scopus 로고    scopus 로고
    • Influence of individual characteristics on outcome of glycemic control in intensive care unit patients with or without diabetes mellitus
    • Rady MY, Johnson DJ, Patel BM, et al. Influence of individual characteristics on outcome of glycemic control in intensive care unit patients with or without diabetes mellitus. Mayo Clinic Proc 2005; 80:1558-1567. (Pubitemid 41747057)
    • (2005) Mayo Clinic Proceedings , vol.80 , Issue.12 , pp. 1558-1567
    • Rady, M.Y.1    Johnson, D.J.2    Patel, B.M.3    Larson, J.S.4    Helmers, R.A.5
  • 25
    • 33947546482 scopus 로고    scopus 로고
    • Glycemic control, diabetic status and mortality in a heterogeneous population of critically ill patients before and during the era of tight glycemic control
    • Krinsley JS. Glycemic control, diabetic status and mortality in a heterogeneous population of critically ill patients before and during the era of tight glycemic control. Semin Thorac Cardiovasc Surg 2006; 18:317-325.
    • (2006) Semin Thorac Cardiovasc Surg , vol.18 , pp. 317-325
    • Krinsley, J.S.1
  • 26
    • 49949090661 scopus 로고    scopus 로고
    • Blood glucose concentration and outcome of critical illness: The impact of diabetes
    • Egi M, Bellomo R, Stachowski E, et al. Blood glucose concentration and outcome of critical illness: The impact of diabetes. Crit Care Med 2008; 36:2249-2255.
    • (2008) Crit Care Med , vol.36 , pp. 2249-2255
    • Egi, M.1    Bellomo, R.2    Stachowski, E.3
  • 27
    • 74049144410 scopus 로고    scopus 로고
    • Diabetes mellitus does not adversely affect outcomes from a critical illness
    • This very large observational cohort study in heterogeneous populations of critically ill patients demonstrates that a premorbid diagnosis of diabetes did not confer an independent risk of mortality
    • Graham BB, Keniston A, Gajic O, et al. Diabetes mellitus does not adversely affect outcomes from a critical illness. Crit Care Med 2010; 38:16-24. This very large observational cohort study in heterogeneous populations of critically ill patients demonstrates that a premorbid diagnosis of diabetes did not confer an independent risk of mortality.
    • (2010) Crit Care Med , vol.38 , pp. 16-24
    • Graham, B.B.1    Keniston, A.2    Gajic, O.3
  • 28
    • 74049118732 scopus 로고    scopus 로고
    • Untangling a sweet web: Hyperglycemia, diabetic status and mortality in critically ill patients
    • Krinsley JS. Untangling a sweet web: Hyperglycemia, diabetic status and mortality in critically ill patients. Crit Care Med 2010; 38:295-296.
    • (2010) Crit Care Med , vol.38 , pp. 295-296
    • Krinsley, J.S.1
  • 29
    • 78651236572 scopus 로고    scopus 로고
    • The interaction of chronic and acute glycemia with mortality in critically ill patients with diabetes
    • This observational cohort study demonstrated the relationship between premorbid glycemic control and glycemic control during critical illness in a cohort of patients with known diabetes
    • Egi M, Bellomo R, Stachowski E, et al. The interaction of chronic and acute glycemia with mortality in critically ill patients with diabetes. Crit Care Med 2011; 39:105-111. This observational cohort study demonstrated the relationship between premorbid glycemic control and glycemic control during critical illness in a cohort of patients with known diabetes.
    • (2011) Crit Care Med , vol.39 , pp. 105-111
    • Egi, M.1    Bellomo, R.2    Stachowski, E.3
  • 30
    • 70649098568 scopus 로고    scopus 로고
    • Hyperglycemia-related mortality in critically ill patients varies with admission diagnosis
    • Falciglia M, Freyberg R, Almenoff PL, et al. Hyperglycemia-related mortality in critically ill patients varies with admission diagnosis. Crit Care Med 2009; 37:3001-3009.
    • (2009) Crit Care Med , vol.37 , pp. 3001-3009
    • Falciglia, M.1    Freyberg, R.2    Almenoff, P.L.3
  • 32
    • 0036482285 scopus 로고    scopus 로고
    • 1c in the Diabetes Control and Complications Trial
    • DOI 10.2337/diacare.25.2.275
    • Rohlfing CL, Wiedmeyer HM, Little RR, et al. Defining the relationship between plasma glucose and HbA(1c): Analysis of glucose profiles and HbA(1c) in the Diabetes Control and Complications Trial. Diab Care 2002; 25:275-278. (Pubitemid 41079621)
    • (2002) Diabetes Care , vol.25 , Issue.2 , pp. 275-278
    • Rohlfing, C.L.1    Wiedmeyer, H.-M.2    Little, R.R.3    England, J.D.4    Tennill, A.5    Goldstein, D.E.6
  • 33
    • 33947285085 scopus 로고    scopus 로고
    • The effects of oxygen therapy in patients presenting to an emergency department with exacerbation of chronic obstructive pulmonary disease
    • Joosten SA, Koh MS, Bu X, et al. The effects of oxygen therapy in patients presenting to an emergency department with exacerbation of chronic obstructive pulmonary disease. Med J Aust 2007; 186:235-238. (Pubitemid 46421440)
    • (2007) Medical Journal of Australia , vol.186 , Issue.5 , pp. 235-238
    • Joosten, S.A.1    Koh, M.S.2    Bu, X.3    Smallwood, D.4    Irving, L.B.5
  • 35
    • 0027030799 scopus 로고
    • Alteration of blood pressure regulation and cerebrovascular disorders in the elderly
    • Shuaib A. Alteration of blood pressure regulation and cerebrovascular disorders in the elderly. Cerebrovasc Brain Metab Rev 1992; 4:329-345.
    • (1992) Cerebrovasc Brain Metab Rev , vol.4 , pp. 329-345
    • Shuaib, A.1
  • 38
    • 45149118855 scopus 로고    scopus 로고
    • Intensive glycemic control in the ACCORD and ADVANCE trials
    • DOI 10.1056/NEJMe0804182
    • Dluhy RG, McMahon GT. Intensive glycemic control in the ACCORD and ADVANCE trials. N Engl J Med 2008; 358:2630-2633. (Pubitemid 351831365)
    • (2008) New England Journal of Medicine , vol.358 , Issue.24 , pp. 2630-2633
    • Dluhy, R.G.1    McMahon, G.T.2
  • 40
    • 48649095222 scopus 로고    scopus 로고
    • Hypoglycemia increases serum interleukin-6 levels in healthy men and women
    • Dotson S, Freeman R, Failing HJ, et al. Hypoglycemia increases serum interleukin-6 levels in healthy men and women. Diab Care 2008; 31:1222-1223.
    • (2008) Diab Care , vol.31 , pp. 1222-1223
    • Dotson, S.1    Freeman, R.2    Failing, H.J.3
  • 41
    • 39049133346 scopus 로고    scopus 로고
    • Insulin-related decrease in cerebral glucose despite normoglycemia in aneurysmal subarachnoid hemorrhage
    • Schlenk F, Graetz D, Nagel A, et al. Insulin-related decrease in cerebral glucose despite normoglycemia in aneurysmal subarachnoid hemorrhage. Crit Care 2008; 12:R9.
    • (2008) Crit Care , vol.12
    • Schlenk, F.1    Graetz, D.2    Nagel, A.3
  • 42
    • 0020517252 scopus 로고
    • Inhibition of the adrenocorticotropin and corticosteroid responses to hypoglycemia after prior stress
    • Keller-Wood ME, Shinsako J, Dallman MF. Inhibition of the adrenocorticotropin and corticosteroid responses to hypoglycemia after prior stress. Endocrinology 1983; 113:491-496. (Pubitemid 13048936)
    • (1983) Endocrinology , vol.113 , Issue.2 , pp. 491-496
    • Keller Wood, M.E.1    Shinsako, J.2    Dallman, M.F.3
  • 43
    • 33646820299 scopus 로고    scopus 로고
    • Antecedent hypoglycemia, catecholamine depletion, and subsequent sympathetic neural responses
    • DOI 10.1210/en.2005-1247
    • Herlein JA, Morgan DA, Phillips BG, et al. Antecedent hypoglycemia, catecholamine depletion, and subsequent sympathetic neural responses. Endocrinology 2006; 147:2781-2788. (Pubitemid 43764615)
    • (2006) Endocrinology , vol.147 , Issue.6 , pp. 2781-2788
    • Herlein, J.A.1    Morgan, D.A.2    Phillips, B.G.3    Haynes, W.G.4    Sivitz, W.I.5
  • 45
    • 0027465021 scopus 로고
    • Hypoglycemia-associated autonomic failure in insulin-dependent diabetes mellitus. Recent antecedent hypoglycemia reduces autonomic responses to, symptoms of, and defense against subsequent hypoglycemia
    • Dagogo-Jack SE, Craft S, Cryer PE. Hypoglycemia-Associated autonomic failure in insulin-dependent diabetes mellitus. Recent antecedent hypoglycemia reduces autonomic responses to, symptoms of, and defense against subsequent hypoglycemia. J Clin Invest 1993; 91:819-828. (Pubitemid 23095255)
    • (1993) Journal of Clinical Investigation , vol.91 , Issue.3 , pp. 819-828
    • Dagogo-Jack, S.E.1    Craft, S.2    Cryer, P.E.3
  • 46
    • 0242300561 scopus 로고    scopus 로고
    • Intermittent high glucose enhances apoptosis related to oxidative stress in human umbilical vein endothelial cells: The role of protein kinase C and NAD(P)H-oxidase activation
    • DOI 10.2337/diabetes.52.11.2795
    • Quagliaro L, Piconi L, Assaloni R, et al. Intermittent high glucose enhances apoptosis related to oxidative stress in human umbilical vein endothelial cells: The role of protein kinase C and NAD(P)H-oxidase activation. Diabetes 2003; 52:2795-2804. (Pubitemid 37339710)
    • (2003) Diabetes , vol.52 , Issue.11 , pp. 2795-2804
    • Quagliaro, L.1    Piconi, L.2    Assaloni, R.3    Martinelli, L.4    Motz, E.5    Ceriello, A.6
  • 47
    • 33645745733 scopus 로고    scopus 로고
    • Activation of oxidative stress by acute glucose fluctuations compared with sustained chronic hyperglycemia in patients with type 2 diabetes
    • Monnier L, Mas E, Ginet C, et al. Activation of oxidative stress by acute glucose fluctuations compared with sustained chronic hyperglycemia in patients with type 2 diabetes. JAMA 2006; 295:1681-1687.
    • (2006) JAMA , vol.295 , pp. 1681-1687
    • Monnier, L.1    Mas, E.2    Ginet, C.3
  • 48
    • 20044376702 scopus 로고    scopus 로고
    • The pathobiology of diabetic complications: A unifying mechanism
    • DOI 10.2337/diabetes.54.6.1615
    • Brownlee M. The pathobiology of diabetic complications: A unifying mechanism. Diabetes 2005; 54:1615-1625. (Pubitemid 40770750)
    • (2005) Diabetes , vol.54 , Issue.6 , pp. 1615-1625
    • Brownlee, M.1
  • 49
    • 34547686072 scopus 로고    scopus 로고
    • Glucose fluctuation on the progression of diabetic macroangiopathy-New findings from monocyte adhesion to endothelial cells
    • DOI 10.1016/j.diabres.2007.01.034, PII S0168822707001647
    • Watada H, Azuma K, Kawamori R. Glucose fluctuation on the progression of diabetic macroangiopathy: New findings from monocyte adhesion to endothelial cells. Diabetes Res Clin Pract 2007; 77 (Suppl 1):S58-S61. (Pubitemid 47212554)
    • (2007) Diabetes Research and Clinical Practice , vol.77 , Issue.SUPPL.
    • Watada, H.1    Azuma, K.2    Kawamori, R.3
  • 50
    • 0035199659 scopus 로고    scopus 로고
    • Intermittent high glucose enhances apoptosis in human umbilical vein endothelial cells in culture
    • Risso A, Mercuri F, Quagliaro L, et al. Intermittent high glucose enhances apoptosis in human umbilical vein endothelial cells in culture. Am J Physiol Endocrinol Metab 2001; 281:E924-E930.
    • (2001) Am J Physiol Endocrinol Metab , vol.281
    • Risso, A.1    Mercuri, F.2    Quagliaro, L.3
  • 51
    • 59749098319 scopus 로고    scopus 로고
    • Intensive insulin therapy for patients in paediatric intensive care: A prospective, randomised controlled study
    • Vlasselaers D, Milants I, Desmet L, et al. Intensive insulin therapy for patients in paediatric intensive care: A prospective, randomised controlled study. Lancet 2009; 373:547-556.
    • (2009) Lancet , vol.373 , pp. 547-556
    • Vlasselaers, D.1    Milants, I.2    Desmet, L.3
  • 52
    • 77957790024 scopus 로고    scopus 로고
    • Glucose dysregulation and neurological injury biomarkers in critically ill children
    • Vanhorebeek I, Gielen M, Boussemaere M, et al. Glucose dysregulation and neurological injury biomarkers in critically ill children. J Clin Endocrinol Metab 2010; 95:4669-4679.
    • (2010) J Clin Endocrinol Metab , vol.95 , pp. 4669-4679
    • Vanhorebeek, I.1    Gielen, M.2    Boussemaere, M.3
  • 53
    • 77956165412 scopus 로고    scopus 로고
    • Clinical need for continuous glucose monitoring in the hospital
    • Joseph JI, Hipszer B, Mraovic B, et al. Clinical need for continuous glucose monitoring in the hospital. J Diab Sci Tech 2009; 3:1309-1318.
    • (2009) J Diab Sci Tech , vol.3 , pp. 1309-1318
    • Joseph, J.I.1    Hipszer, B.2    Mraovic, B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.