Understanding glycemic control in the critically ill: Three domains are better than one

Intensive Care Medicine

Volumn 37, Issue 3, 2011, Pages 382-384

  Krinsley, James S ^a,b  

^a STAMFORD HOSPITAL   (United States)

^b College of Physicians and Surgeons ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE;

CRITICAL ILLNESS; DIABETIC PATIENT; DISEASE SEVERITY; EDITORIAL; GLUCOSE BLOOD LEVEL; GLYCEMIC CONTROL; HUMAN; HYPOGLYCEMIA; INTENSIVE CARE UNIT; MONITORING; MORTALITY;

BLOOD GLUCOSE; CRITICAL ILLNESS; HUMANS; HYPOGLYCEMIA; HYPOGLYCEMIC AGENTS; INSULIN; INTENSIVE CARE UNITS; REPRODUCIBILITY OF RESULTS; TREATMENT OUTCOME; UNITED STATES;

EID: 79953809765     PISSN: 03424642     EISSN: 14321238     Source Type: Journal    
DOI: 10.1007/s00134-010-2110-3     Document Type: Editorial

References (23)

1. Van den Berghe G, Wouters P, Weekers F, Verwaest C, Bruyninckx F, Schetz M, Vlasslaers D, Ferdinande P, Lauwers P, Bouillon R (2001) Intensive insulin therapy in critically ill patients. N Engl J Med 345:1359-1367
2. Google Scholar website (2010) http://scholar.google.com. Accessed 20 Sep 2010
3. Krinsley JS (2004) The effect of an intensive glucose management protocol on the mortality of critically ill adult patients. Mayo Clinic Proc 79:992-1000
4. American College of Endocrinology (2004) Position statement on inpatient diabetes and metabolic control. Endoc Prac 10:77-82
5. Dellinger RP, Carlet JM, Masur H, Gerlach H, Calandra T, Cohen J, Gea- Banacloche J, Keh D, Marshall JC, Parker MM, Ramsay G, Zimmerman JL, Vincent JL, Levy MM, Surviving Sepsis Campaign Management Guidelines Committee (2004) Surviving Sepsis Campaign guidelines for management of severe sepsis and septic shock. Crit Care Med 32:858-873 (Pubitemid 38344143)
6. Preiser JC, Devos P, Ruiz-Santana S, Melot C, Annane D, Groeneveld J, Iapichino G, Leverve X, Nitenberg G, Singer P, Wernerman J, Joannidis M, Stecher A, Chioleiro R (2009) A prospective randomized multi-centre controlled trial on tight glucose control by intensive insulin therapy in adult intensive care units: the Glucontrol study. Intensive Care Med 35:1738-1748
7. Brunkhorst FM, Engel C, Bloos F, Meier-Hellmann A, Ragaller M, Weiler N, Moerer O, GruendLing M, Oppert M, Grond S, Olthoff D, Jaschinski U, John S, Rossaint R, Welte T, Schaefer M, Kern P, Kuhnt E, Kiehntopf M, Hartog C, Natanson C, Loeffler M, Reinhart K (2008) Intensive insulin therapy and pentastarch resuscitation in severe sepsis. N Eng J Med 358:125-139
8. Van den Berghe G, Wilmer A, Hermans G, Meersseman W, Wouters PF, Milants I, Van Wijngaerden E, Bobbaers H, Bouillon R (2006) Intensive insulin therapy in the medical ICU. N Engl J Med 354:449-461 (Pubitemid 43200296)
9. The NICE-SUGAR study investigators (2009) Intensive versus conventional insulin therapy in critically ill patients. N Engl J Med 360:1283-1297
10. Meyfroidt G, Keenan DM, Wang X, Wouters P, Veldhuis J, Van den Berghe G (2010) Dynamic characteristics of blood glucose time series during the course of critical illness: effects of intensive insulin therapy and relative association with mortality. Crit Care Med 38:1021-1029
11. Krinsley JS, Grover A (2007) Severe hypoglycemia in critically ill patients: risk factors and outcomes. Crit Care Med 35:2262-2267 (Pubitemid 47476221)
12. Egi M, Bellomo R, Stachowski E, French C, Hart G, Taori G, Hegarty C, Bailey M (2010) Hypoglycemia and outcome in critical illness. Mayo Clinic Proc 85:217-224
13. Bagshaw S, Bellomo R, Jacka M, Egi M, Hart G, George C (2009) The impact of early hypoglycemia and glycemic variability on outcome in critical illness. Crit Care 13:R91
14. Egi M, Bellomo R, Stachowski E, French CJ, Hart G (2006) Variability of blood glucose monitoring and short term mortality of critically ill patients. Anesthesiology 105:244-252 (Pubitemid 44148168)
15. Krinsley JS (2008) Glycemic variability: a strong, independent predictor of mortality in critically ill patients. Crit Care Med 36:3008-3013
16. Hermanides J, Vriesendorp T, Bosman R, Zandstra D, Hoekstra J, DeVries J (2010) Glucose variability is associated with intensive care unit mortality. Crit Care Med 38:838-842
17. Ali NA, O'Brien JA, Dungan K, Phillips G, Marsh CB, Lemeshow S, Connors AF, Preiser JC (2008) Glucose variability and mortality in patients with sepsis. Crit Care Med 36:2316-2321
18. Mackenzie I, Whitehouse T, Nightingale P (2011) The metrics of glycaemic control in critical care. Intensive Care Med. doi: 10.1007/s00134-010-2103-2
19. Krinsley JS (2006) Glycemic control, diabetic status and mortality in a heterogeneous population of critically ill patients before and during the era of tight glycemic control. Semin Thorac Cardiovasc Surg 18:317-325
20. Krinsley JS (2009) Glycemic variability in critically ill patients: the impact of diabetes. J Diab Sci Tech 3:1292-1301
21. Graham B, Keniston A, Gajic O, Trillo A, Cesar A, Medvedev S, Douglas I (2010) Diabetes mellitus does not adversely affect outcomes from a critical illness. Crit Care Med 38:16-24
22. Egi M, Bellomo R, Stachowski E, French CJ, Hart GK, Hegarty C, Bailey M (2008) Blood glucose concentration and outcome of critical illness: the impact of diabetes. Crit Care Med 36:2249-2255
23. Joseph J, Hipszer B, Mraovic B, Chervoneva I, Joseph M, Grunwald Z (2009) Clinical need for continuous glucose monitoring in the hospital. J Diab Sci Tech 3:1309-1318