Friedel-crafts 3-(2-bromobenzoylation) of indoles and intramolecular direct arylation: An efficient route to indenoindolones

Synthesis

Volumn 44, Issue 4, 2012, Pages 619-627

  Guchhait, Sankar K ^a   Kashyap, Maneesh ^a  

^a NATIONAL INSTITUTE OF PHARMACEUTICAL EDUCATION AND RESEARCH NIPER   (India)

Author keywords

acylation; arylation; catalysis; coupling; heterocycles; indoles; Lewis acids; palladium

Indexed keywords

ARYLATIONS; BIOACTIVE COMPOUNDS; FRIEDEL-CRAFTS; FUNCTIONALIZED; HETEROCYCLES; HIGH YIELD; INDOLES; LEWIS ACID; TWO-STEP APPROACH;

ACYLATION; CATALYSIS; CHLORINE COMPOUNDS; COUPLINGS; FRIEDEL-CRAFTS REACTION; PALLADIUM;

AROMATIC COMPOUNDS;

1 BENZYL 3 (2 BROMOBENZYL) 1 METHYL 1H INDOLE; 10 METHOXYBENZO[5,6]INDENO[1,2 B]INDOL 12(7H)ONE; 2 FLUROINDENO[1,2 B]INDOL 10(5H)ONE; 2,3,4 TRIMETHOXY 5 METHYLINDENO[1,2 B]INDOL 10(5H)ONE; 2,3,4 TRIMETHOXYINDENO[1,2 B]INDOL 10(5H)ONE; 2,3,4,8 TETRAMETHOXYINDENO[1,2 B]INDOL 10(5H)ONE; 3 (2 BROMO 2 NAPHTHOYL) 5 METHOXY 1H INDOLE; 3 (2 BROMO 3,4,5 TRIMETHOXYBENZOYL) 1 METHYL 1H INDOLE; 3 (2 BROMO 3,4,5 TRIMETHOXYBENZOYL) 1H INDOLE; 3 (2 BROMO 3,4,5 TRIMETHOXYBENZOYL) 5 METHOXY 1H INDOLE; 3 (2 BROMO 4,5 DIMETHOXYBENZOYL) 1H INDOLE; 3 (2 BROMO 4,5 DIMETHOXYBENZOYL) 5 METHOXY 1H INDOLE; 3 (2 BROMO 5 FLUOROBENZOYL) 1H INDOLE; 3 (2 BROMO 5 METHOXYBENZOYL) 5 METHOXY 1H INDOLE; 3 (2 BROMOBENZOYL) 1 METHYL 5 PHENYL 1H INDOLE; 3 (2 BROMOBENZOYL) 1H INDOLE; 3 (2 BROMOBENZOYL) 5 METHOXY 1 METHYL 1H INDOLE; 3 (2 BROMOBENZOYL) 5 METHOXY 1H INDOLE; 3 (2 BROMOBENZYL) 1 METHYL 1H INDOLE; 5 BENZYLINDENOL[1,2 B]INDOL 10(5H) ONE; 5 METHYL 8 PHENYLINDENOL[1,2 B]INDOL 10(5H)ONE; 5 METHYLINDENO[1,2 B]INDOL 10(5H) ONE; 8 METHOXY 5 METHYLINDENOL [1,2 B]INDOL 10(5H) ONE; 8 METHOXYINDENO[1,2 B]INDOL 10(5H)ONE; INDENO[1,2 B]INDOL 10(5H)ONE; INDOLE DERIVATIVE; UNCLASSIFIED DRUG;

ACYLATION; ARTICLE; ARYLATION; CHEMICAL REACTION; DRUG ANALYSIS; DRUG STRUCTURE; DRUG SYNTHESIS; OLIGOMERIZATION;

EID: 84857034811     PISSN: 00397881     EISSN: 1437210X     Source Type: Journal    
DOI: 10.1055/s-0031-1289663     Document Type: Article

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