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Volumn 30, Issue 4, 2012, Pages 554-560

Lysine392, a K63-linked ubiquitination site in NEMO, mediates inflammatory osteoclastogenesis and osteolysis

Author keywords

NEMO; osteolysis; polymethylmethacrylate; polyubiquitination

Indexed keywords

I KAPPA B; I KAPPA B KINASE GAMMA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LYSINE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; OSTEOCLAST DIFFERENTIATION FACTOR; POLY(METHYL METHACRYLATE); STRESS ACTIVATED PROTEIN KINASE;

EID: 84857033023     PISSN: 07360266     EISSN: 1554527X     Source Type: Journal    
DOI: 10.1002/jor.21555     Document Type: Article
Times cited : (12)

References (36)
  • 2
    • 4444310005 scopus 로고    scopus 로고
    • Mechanisms of inflammatory mediators in bone loss diseases
    • Rosier R.N. Evans C.H. editors. Rosemont, IL: AAOS.
    • Abu-Amer Y,. 2003. Mechanisms of inflammatory mediators in bone loss diseases. In:, Rosier RN, Evans CH, editors. Molecular biology in orthopedics. Rosemont, IL: AAOS. 229-239.
    • (2003) Molecular Biology in Orthopedics , pp. 229-239
    • Abu-Amer, Y.1
  • 3
    • 0032715364 scopus 로고    scopus 로고
    • Cytokine receptor profile of arthroplasty macrophages foreign body giant cells and mature osteoclasts
    • Neale SD, Athanasou NA,. 1999. Cytokine receptor profile of arthroplasty macrophages foreign body giant cells and mature osteoclasts. Acta Orthop Scand 70: 452-458.
    • (1999) Acta Orthop Scand , vol.70 , pp. 452-458
    • Neale, S.D.1    Athanasou, N.A.2
  • 5
    • 18244372936 scopus 로고    scopus 로고
    • Arthroplasty membrane-derived fibroblasts directly induce osteoclast formation and osteolysis in aseptic loosening
    • DOI 10.1016/j.orthres.2004.10.006, PII S0736026604002438
    • Sabokbar A, Itonaga I, Sun SG, et al. 2005. Arthroplasty membrane-derived fibroblasts directly induce osteoclast formation and osteolysis in aseptic loosening. J Orthop Res 23: 511-519. (Pubitemid 40631320)
    • (2005) Journal of Orthopaedic Research , vol.23 , Issue.3 , pp. 511-519
    • Sabokbar, A.1    Itonaga, I.2    Sun, S.G.3    Kudo, O.4    Athanasou, N.A.5
  • 6
    • 60949083515 scopus 로고    scopus 로고
    • NF-κB modulators in osteolytic bone diseases
    • Xu J, Wu HF, Ang ES, et al. 2009. NF-κB modulators in osteolytic bone diseases. Cytokine Growth Factor Rev 20: 7-17.
    • (2009) Cytokine Growth Factor Rev , vol.20 , pp. 7-17
    • Xu, J.1    Wu, H.F.2    Ang, E.S.3
  • 7
    • 33144481680 scopus 로고    scopus 로고
    • Osteoclasts; Culprits in inflammatory osteolysis
    • Teitelbaum SL,. 2006. Osteoclasts; culprits in inflammatory osteolysis. Arthritis Res Ther 8: 201.
    • (2006) Arthritis Res Ther , vol.8 , pp. 201
    • Teitelbaum, S.L.1
  • 8
    • 0035206443 scopus 로고    scopus 로고
    • Minireview: The OPG/RANKL/RANK system
    • DOI 10.1210/en.142.12.5050
    • Khosla S,. 2001. Minireview: the OPG/RANKL/RANK system. Endocrinology 142: 5050-5055. (Pubitemid 33131929)
    • (2001) Endocrinology , vol.142 , Issue.12 , pp. 5050-5055
    • Khosla, S.1
  • 10
    • 34548418499 scopus 로고    scopus 로고
    • Aseptic loosening of total joint replacements: Mechanisms underlying osteolysis and potential therapies
    • Abu-Amer Y, Darwech I, Clohisy JC,. 2007. Aseptic loosening of total joint replacements: mechanisms underlying osteolysis and potential therapies. Arthritis Res Ther 9 (Suppl 1): S6.
    • (2007) Arthritis Res Ther , vol.9 , Issue.SUPPL. 1
    • Abu-Amer, Y.1    Darwech, I.2    Clohisy, J.C.3
  • 11
    • 27644479269 scopus 로고    scopus 로고
    • TNF-alpha and pathologic bone resorption
    • Boyce BF, Li P, Yao Z, et al. 2005. TNF-alpha and pathologic bone resorption. Keio J Med 54: 127-131.
    • (2005) Keio J Med , vol.54 , pp. 127-131
    • Boyce, B.F.1    Li, P.2    Yao, Z.3
  • 14
    • 52049084316 scopus 로고    scopus 로고
    • Mechanisms modulating inflammatory osteolysis: A review with insights into therapeutic targets
    • Wei S, Siegal GP,. 2008. Mechanisms modulating inflammatory osteolysis: a review with insights into therapeutic targets. Pathol Res Pract 204: 695-706.
    • (2008) Pathol Res Pract , vol.204 , pp. 695-706
    • Wei, S.1    Siegal, G.P.2
  • 15
    • 0142241267 scopus 로고    scopus 로고
    • Mitogen-activated protein (MAP) kinases mediate PMMA-induction of osteoclasts
    • DOI 10.1016/S0736-0266(03)00081-0
    • Abbas S, Clohisy JC, Abu-Amer Y,. 2003. Mitogen-activated protein (MAP) kinases mediate PMMA-induction of osteoclasts. J Orthop Res 21: 1041-1048. (Pubitemid 37322386)
    • (2003) Journal of Orthopaedic Research , vol.21 , Issue.6 , pp. 1041-1048
    • Abbas, S.1    Clohisy, J.C.2    Abu-Amer, Y.3
  • 16
    • 33746151316 scopus 로고    scopus 로고
    • Map kinase c-Jun N-terminal kinase mediates PMMA induction of osteoclasts
    • DOI 10.1002/jor.20199
    • Yamanaka Y, Abu-Amer Y, Faccio R, et al. 2006. Map kinase c-JUN N-terminal kinase mediates PMMA induction of osteoclasts. J Orthop Res 24: 1349-1357. (Pubitemid 44083250)
    • (2006) Journal of Orthopaedic Research , vol.24 , Issue.7 , pp. 1349-1357
    • Yamanaka, Y.1    Abu-Amer, Y.2    Faccio, R.3    Clohisy, J.C.4
  • 17
    • 0036138694 scopus 로고    scopus 로고
    • The phosphatidylinositol 3-Kinase, p38, and extracellular signal-regulated kinase pathways are involved in osteoclast differentiation
    • DOI 10.1016/S8756-3282(01)00657-3, PII S8756328201006573
    • Lee SE, Woo KM, Kim SY, et al. 2002. The phosphatidylinositol 3-kinase, p38, and extracellular signal-regulated kinase pathways are involved in osteoclast differentiation. Bone 30: 71-77. (Pubitemid 34044303)
    • (2002) Bone , vol.30 , Issue.1 , pp. 71-77
    • Lee, S.E.1    Woo, K.M.2    Kim, S.Y.3    Kim, H.-M.4    Kwack, K.5    Lee, Z.H.6    Kim, H.-H.7
  • 18
    • 41449101904 scopus 로고    scopus 로고
    • Role of the NF-κB axis in immune modulation of osteoclasts and bone loss
    • DOI 10.1080/08916930701694543, PII 789048434, Osteoimmunology in Skeletal Cell Biology and Disease
    • Abu-Amer Y, Darwech I, Otero J,. 2008. Role of the NF-kappaB axis in immune modulation of osteoclasts and bone loss. Autoimmunity 41: 204-211. (Pubitemid 351454990)
    • (2008) Autoimmunity , vol.41 , Issue.3 , pp. 204-211
    • Abu-Amer, Y.1    Darwech, I.2    Otero, J.3
  • 19
    • 4444376712 scopus 로고    scopus 로고
    • Signaling to NF-kappaB
    • Hayden MS, Ghosh S,. 2004. Signaling to NF-kappaB. Genes Dev 18: 2195-2224.
    • (2004) Genes Dev , vol.18 , pp. 2195-2224
    • Hayden, M.S.1    Ghosh, S.2
  • 20
    • 38849199203 scopus 로고    scopus 로고
    • Shared Principles in NF-[kappa]B Signaling
    • Hayden MS, Ghosh S,. 2008. Shared Principles in NF-[kappa]B Signaling. Cell 132: 344-362.
    • (2008) Cell , vol.132 , pp. 344-362
    • Hayden, M.S.1    Ghosh, S.2
  • 21
    • 4444306858 scopus 로고    scopus 로고
    • The IκB kinase (IKK) inhibitor, NEMO-binding domain peptide, blocks osteoclastogenesis and bone erosion in inflammatory arthritis
    • DOI 10.1074/jbc.C400258200
    • Dai S, Hirayama T, Abbas S, et al. 2004. The IκB kinase (IKK) inhibitor, NEMO-binding domain peptide, blocks osteoclastogenesis and bone erosion in inflammatory arthritis. J Biol Chem 279: 37219-37222. (Pubitemid 39195425)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.36 , pp. 37219-37222
    • Dai, S.1    Hirayama, T.2    Abbas, S.3    Abu-Amer, Y.4
  • 22
    • 0034284715 scopus 로고    scopus 로고
    • Selective inhibition of NF-κB activation by a peptide that blocks the interaction of NEMO with the IkappaB kinase complex
    • May MJ, D'Acquisto F, Madge LA, et al. 2000. Selective inhibition of NF-κB activation by a peptide that blocks the interaction of NEMO with the IkappaB kinase complex. Science 289: 1550-1554.
    • (2000) Science , vol.289 , pp. 1550-1554
    • May, M.J.1    D'Acquisto, F.2    Madge, L.A.3
  • 24
    • 77958517570 scopus 로고    scopus 로고
    • 3 (NEMO) protein in health and disease
    • 3 (NEMO) protein in health and disease. J Cell Mol Med 14: 2404-2414.
    • (2010) J Cell Mol Med , vol.14 , pp. 2404-2414
    • Shifera, A.S.1
  • 25
    • 77957677615 scopus 로고    scopus 로고
    • Polyubiquitin conjugation to NEMO by triparite motif protein 23 (TRIM23) is critical in antiviral defense
    • Arimoto KI, Funami K, Saeki Y, et al. 2010. Polyubiquitin conjugation to NEMO by triparite motif protein 23 (TRIM23) is critical in antiviral defense. Proc Natl Acad Sci USA 107: 15856-15861.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 15856-15861
    • Arimoto, K.I.1    Funami, K.2    Saeki, Y.3
  • 26
    • 59149093017 scopus 로고    scopus 로고
    • The zinc finger of NEMO is a functional ubiquitin-binding domain
    • Cordier F, Grubisha O, Traincard F, et al. 2009. The zinc finger of NEMO is a functional ubiquitin-binding domain. J Biol Chem 284: 2902-2907.
    • (2009) J Biol Chem , vol.284 , pp. 2902-2907
    • Cordier, F.1    Grubisha, O.2    Traincard, F.3
  • 27
    • 25844459154 scopus 로고    scopus 로고
    • NF-κB: Linking inflammation and immunity to cancer development and progression
    • DOI 10.1038/nri1703
    • Karin M, Greten FR,. 2005. NF-kappaB: linking inflammation and immunity to cancer development and progression. Nat Rev Immunol 5: 749-759. (Pubitemid 41400849)
    • (2005) Nature Reviews Immunology , vol.5 , Issue.10 , pp. 749-759
    • Karin, M.1    Greten, F.R.2
  • 28
    • 0346505340 scopus 로고    scopus 로고
    • The IKK NF-κB system: A treasure trove for drug development
    • Karin M, Yamamoto Y, Wang M,. 2004. The IKK NF-kB system: a treasure trove for drug development. Nat Rev 3: 17-26. (Pubitemid 38088695)
    • (2004) Nature Reviews Drug Discovery , vol.3 , Issue.1 , pp. 17-26
    • Karin, M.1    Yamamoto, Y.2    Wang, Q.M.3
  • 29
    • 33746175063 scopus 로고    scopus 로고
    • Inhibition of IKK activation, through sequestering NEMO, blocks PMMA-induced osteoclastogenesis and calvarial inflammatory osteolysis
    • DOI 10.1002/jor.20184
    • Clohisy JC, Yamanaka Y, Faccio R, et al. 2006. Inhibition of IKK activation, through sequestering NEMO, blocks PMMA-induced osteoclastogenesis and calvarial inflammatory osteolysis. J Orthop Res 24: 1358-1365. (Pubitemid 44083251)
    • (2006) Journal of Orthopaedic Research , vol.24 , Issue.7 , pp. 1358-1365
    • Clohisy, J.C.1    Yamanaka, Y.2    Faccio, R.3    Abu-Amer, Y.4
  • 30
    • 4444306858 scopus 로고    scopus 로고
    • The IκB kinase (IKK) inhibitor, NEMO-binding domain peptide, blocks osteoclastogenesis and bone erosion in inflammatory arthritis
    • DOI 10.1074/jbc.C400258200
    • Dai S, Hirayama T, Abbas S, et al. 2004. The IkappaB kinase (IKK) inhibitor, NEMO-binding domain peptide, blocks osteoclastogenesis and bone erosion in inflammatory arthritis. J Biol Chem 279: 37219-37222. (Pubitemid 39195425)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.36 , pp. 37219-37222
    • Dai, S.1    Hirayama, T.2    Abbas, S.3    Abu-Amer, Y.4
  • 31
    • 47249087279 scopus 로고    scopus 로고
    • Cutting Edge: K63-linked polyubiquitination of NEMO modulates TLR signaling and inflammation in vivo
    • Ni C-Y, Wu Z-H, Florence WC, et al. 2008. Cutting Edge: K63-linked polyubiquitination of NEMO modulates TLR signaling and inflammation in vivo. J Immunol 180: 7107-7111.
    • (2008) J Immunol , vol.180 , pp. 7107-7111
    • Ni, C.-Y.1    Wu, Z.-H.2    Florence, W.C.3
  • 32
    • 0037226134 scopus 로고    scopus 로고
    • RANKL is an essential cytokine mediator of polymethylmethacrylate particle-induced osteoclastogenesis
    • DOI 10.1016/S0736-0266(02)00133-X, PII S073602660200133X
    • Clohisy J, Frazier E, Hirayama T, et al. 2003. RANKL is an essential cytokine mediator of PMMA particle-induced osteoclastogenesis. J Orthop Res 21: 202-212. (Pubitemid 36322538)
    • (2003) Journal of Orthopaedic Research , vol.21 , Issue.2 , pp. 202-212
    • Clohisy, J.C.1    Frazier, E.2    Hirayama, T.3    Abu-Amer, Y.4
  • 34
    • 23144449789 scopus 로고    scopus 로고
    • Ubiquitin signalling in the NF-kB pathway
    • Chen ZJ,. 2005. Ubiquitin signalling in the NF-kB pathway. Nat Cell Biol 7: 758-765.
    • (2005) Nat Cell Biol , vol.7 , pp. 758-765
    • Chen, Z.J.1
  • 35
    • 11144340996 scopus 로고    scopus 로고
    • Inflammatory diseases: Is ubiquitinated NEMO at the hub?
    • DOI 10.1016/j.cub.2004.11.040, PII S0960982204009297
    • Burns KA, Martinon F,. 2004. Inflammatory diseases: is ubiquitinated NEMO at the hub? Curr Biol 14: R1040-R1042. (Pubitemid 40033345)
    • (2004) Current Biology , vol.14 , Issue.24
    • Burns, K.A.1    Martinon, F.2
  • 36
    • 70450222517 scopus 로고    scopus 로고
    • Endosomal damage and TLR2 mediated inflammasome activation by alkane particles in the generation of aseptic osteolysis
    • Maitra R, Clement CC, Scharf B, et al. 2009. Endosomal damage and TLR2 mediated inflammasome activation by alkane particles in the generation of aseptic osteolysis. Mol Immunol 47: 175-184.
    • (2009) Mol Immunol , vol.47 , pp. 175-184
    • Maitra, R.1    Clement, C.C.2    Scharf, B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.