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Volumn 101, Issue 3, 2012, Pages 348-353

Lamotrigine treatment reverses depressive-like behavior and alters BDNF levels in the brains of maternally deprived adult rats

Author keywords

BDNF; Depression; Lamotrigine; Maternal deprivation; NGF

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; LAMOTRIGINE; NERVE GROWTH FACTOR; SODIUM CHLORIDE;

EID: 84857028255     PISSN: 00913057     EISSN: 18735177     Source Type: Journal    
DOI: 10.1016/j.pbb.2012.01.019     Document Type: Article
Times cited : (28)

References (64)
  • 1
    • 33947155494 scopus 로고    scopus 로고
    • Cognitive impairment associated to HPA axis hyperactivity after maternal separation in rats
    • DOI 10.1016/j.psyneuen.2006.12.013, PII S030645300700008X
    • Aisa B, Tordera R, Lasheras B, Del Río J, Ramírez MJ. Cognitive impairment associated to HPA axis hyperactivity after maternal separation in rats. Psychoneuroendocrinol 2007;32:256-66. (Pubitemid 46400278)
    • (2007) Psychoneuroendocrinology , vol.32 , Issue.3 , pp. 256-266
    • Aisa, B.1    Tordera, R.2    Lasheras, B.3    Del, R.J.4    Ramirez, M.J.5
  • 6
    • 59849095290 scopus 로고    scopus 로고
    • Chronic administration of mood stabilizers upregulates BDNF and bcl-2 expression levels in rat frontal cortex
    • Chang YC, Rapoport SI, Rao JS. Chronic administration of mood stabilizers upregulates BDNF and bcl-2 expression levels in rat frontal cortex. Neurochem Res 2009;34: 536-41.
    • (2009) Neurochem Res , vol.34 , pp. 536-541
    • Chang, Y.C.1    Rapoport, S.I.2    Rao, J.S.3
  • 7
    • 0035881828 scopus 로고    scopus 로고
    • Increased hippocampal bdnf immunoreactivity in subjects treated with antidepressant medication
    • Chen B, Dowlatshahi D, MacQueen GM, Wang JF, Young LT. Increased hippocampal bdnf immunoreactivity in subjects treated with antidepressant medication. Biol Psychiatry 2001;50:260-5.
    • (2001) Biol Psychiatry , vol.50 , pp. 260-265
    • Chen, B.1    Dowlatshahi, D.2    MacQueen, G.M.3    Wang, J.F.4    Young, L.T.5
  • 8
    • 67449143086 scopus 로고    scopus 로고
    • Neonatal maternal separation increases brain-derived neurotrophic factor and tyrosine kinase receptor B expression in the descending pain modulatory system
    • Chung EK, Bian ZX, Xu HX, Sung JJ. Neonatal maternal separation increases brain-derived neurotrophic factor and tyrosine kinase receptor B expression in the descending pain modulatory system. Neurosignals 2009;17:213-21.
    • (2009) Neurosignals , vol.17 , pp. 213-221
    • Chung, E.K.1    Bian, Z.X.2    Xu, H.X.3    Sung, J.J.4
  • 9
    • 0032052202 scopus 로고    scopus 로고
    • Early maternal separation increases NGF expression in the developing rat hippocampus
    • DOI 10.1016/S0091-3057(97)00512-1, PII S0091305797005121
    • Cirulli F, Micera A, Alleva E, Aloe L. Early maternal separation increases NGF expression in the developing rat hippocampus. Pharmacol Biochem Behav 1998;59:853-8. (Pubitemid 28237896)
    • (1998) Pharmacology Biochemistry and Behavior , vol.59 , Issue.4 , pp. 853-858
    • Cirulli, F.1    Micera, A.2    Alleva, E.3    Aloe, L.4
  • 10
    • 0034727486 scopus 로고    scopus 로고
    • NGF expression in the developing rat brain effects of maternal separation
    • Cirulli F, Alleva E, Antonelli A, Aloe L. NGF expression in the developing rat brain effects of maternal separation. Brain Res Dev Brain Res 2000;123:129-34.
    • (2000) Brain Res Dev Brain Res , vol.123 , pp. 129-134
    • Cirulli, F.1    Alleva, E.2    Antonelli, A.3    Aloe, L.4
  • 11
    • 0037688084 scopus 로고    scopus 로고
    • Finding the intracellular signaling pathways affected by mood disorder treatments
    • DOI 10.1016/S0896-6273(03)00195-8
    • Coyle JT, Duman RS. Finding the intracellular signaling pathways affected bymood disorder treatments. Neuron 2003;38:157-60. (Pubitemid 36555643)
    • (2003) Neuron , vol.38 , Issue.2 , pp. 157-160
    • Coyle, J.T.1    Duman, R.S.2
  • 12
    • 0029081299 scopus 로고
    • Active behaviors in the rat forced swimming test differentially produced by serotonergic and noradrenergic antidepressants
    • Detke MJ, Rickels M, Lucki I. Active behaviors in the rat forced swimming test differentially produced by serotonergic and noradrenergic antidepressants. Psychopharmacol 1995;121:66-72.
    • (1995) Psychopharmacol , vol.121 , pp. 66-72
    • Detke, M.J.1    Rickels, M.2    Lucki, I.3
  • 13
    • 0031681434 scopus 로고    scopus 로고
    • Novel therapeutic approaches beyond the serotonin receptor
    • DOI 10.1016/S0006-3223(98)00031-6, PII S0006322398000316
    • Duman RS. Novel therapeutic approaches beyond the serotonin receptor. Biol Psychiatry 1998;44:324-35. (Pubitemid 28432643)
    • (1998) Biological Psychiatry , vol.44 , Issue.5 , pp. 324-335
    • Duman, R.S.1
  • 14
    • 1642307557 scopus 로고    scopus 로고
    • Role of Neurotrophic Factors in the Etiology and Treatment of Mood Disorders
    • Duman RS. Role of neurotrophic factors in the etiology and treatment of mood disorders. Neuromolecular Med 2004;5:11-25. (Pubitemid 38391953)
    • (2004) NeuroMolecular Medicine , vol.5 , Issue.1 , pp. 11-25
    • Duman, R.S.1
  • 15
    • 0028569188 scopus 로고
    • Molecular psychiatry. Adaptations of receptor-coupled signal transduction pathways underlying stress- and drug-induced neural plasticity
    • 18212
    • Duman RS, Heninger GR, Nestler EJ.Molecular psychiatry. Adaptations of receptor-coupled signal transduction pathways underlying stress- and drug-induced neural plasticity. J Nerv Ment Dis 1994;18212:692.
    • (1994) J Nerv Ment Dis , pp. 692
    • Duman, R.S.1    Heninger, G.R.2    Nestler, E.J.3
  • 17
    • 33646025518 scopus 로고    scopus 로고
    • Adult life behavioral consequences of early maternal separation are alleviated by escitalopram treatment in a rat model of depression
    • El Khoury A, Gruber SH, Mørk A, Mathé AA. Adult life behavioral consequences of early maternal separation are alleviated by escitalopram treatment in a rat model of depression. Prog Neuropsychopharmacol Biol Psychiatry 2006;30:535-40.
    • (2006) Prog Neuropsychopharmacol Biol Psychiatry , vol.30 , pp. 535-540
    • El Khoury, A.1    Gruber, S.H.2    Mørk, A.3    Mathé, A.A.4
  • 18
    • 34250831728 scopus 로고    scopus 로고
    • Early maternal separation followed by later stressors leads to dysregulation of the HPA-axis and increases in hippocampal NGF and NT-3 levels in a rat model
    • Faure J, Uys JD, Marais L, Stein DJ, Daniels WM. Early maternal separation followed by later stressors leads to dysregulation of the HPA-axis and increases in hippocampal NGF and NT-3 levels in a rat model. Metab Brain Dis 2006;21:181-8.
    • (2006) Metab Brain Dis , vol.21 , pp. 181-188
    • Faure, J.1    Uys, J.D.2    Marais, L.3    Stein, D.J.4    Daniels, W.M.5
  • 19
    • 0033232480 scopus 로고    scopus 로고
    • The role of corticotropin-releasing factor-norepinephrine systems in mediating the effects of early experience on the development of behavioral and endocrine responses to stress
    • DOI 10.1016/S0006-3223(99)00237-1, PII S0006322399002371
    • Francis DD, Caldji C, Champagne F, Plotsky PM, Meaney MJ. The role of corticotropinreleasing factor-norepinephrine systems inmediating the effects of early experience on the development of behavioral and endocrine responses to stress. Biol Psychiatry 1999;46:1153-66. (Pubitemid 30114434)
    • (1999) Biological Psychiatry , vol.46 , Issue.9 , pp. 1153-1166
    • Francis, D.D.1    Caldji, C.2    Champagne, F.3    Plotsky, P.M.4    Meaney, M.J.5
  • 20
    • 38349097619 scopus 로고    scopus 로고
    • Acute administration of ketamine induces antidepressant-like effects in the forced swimming test and increases BDNF levels in the rat hippocampus
    • Garcia LS, Comim CM, Valvassori SS, Réus GZ, Barbosa LM, Andreazza AC, et al. Acute administration of ketamine induces antidepressant-like effects in the forced swimming test and increases BDNF levels in the rat hippocampus. Prog Neuropsychopharmacol Biol Psychiatry 2008a;321:140-4.
    • (2008) Prog Neuropsychopharmacol Biol Psychiatry , vol.321 , pp. 140-144
    • Garcia, L.S.1    Comim, C.M.2    Valvassori, S.S.3    Réus, G.Z.4    Barbosa, L.M.5    Andreazza, A.C.6
  • 21
    • 56049120097 scopus 로고    scopus 로고
    • Chronic administration of ketamine elicits antidepressant-like effects in rats without affecting hippocampal brain-derived neurotrophic factor protein levels
    • Garcia LS, Comim CM, Valvassori SS, Réus GZ, Andreazza AC, Stertz L, et al. Chronic administration of ketamine elicits antidepressant-like effects in rats without affecting hippocampal brain-derived neurotrophic factor protein levels. Basic Clin Pharmacol Toxicol 2008b;103:502-6.
    • (2008) Basic Clin Pharmacol Toxicol , vol.103 , pp. 502-506
    • Garcia, L.S.1    Comim, C.M.2    Valvassori, S.S.3    Réus, G.Z.4    Andreazza, A.C.5    Stertz, L.6
  • 22
    • 0344585351 scopus 로고    scopus 로고
    • Nicotine Attenuates Arachidonic Acid-Induced Apoptosis of Spinal Cord Neurons by Preventing Depletion of Neurotrophic Factors
    • Garrido R, Springer JE, Hennig B, Toborek M. Apoptosis of spinal cord neurons by preventing depletion nicotine attenuates arachidonic acid-induced of neurotrophic factors. J Neurotrauma 2003;20:1201-13. (Pubitemid 37467283)
    • (2003) Journal of Neurotrauma , vol.20 , Issue.11 , pp. 1201-1213
    • Garrido, R.1    Springer, J.E.2    Hennig, B.3    Toborek, M.4
  • 24
    • 0031979135 scopus 로고    scopus 로고
    • Social deprivation of neonatal, adolescent, and adult rats has distinct neurochemical and behavioral consequences
    • Hall FS. Social deprivation of neonatal, adolescent, and adult rats has distinct neurochemical and behavioral consequences. Crit Rev Neurobiol 1998;12:129-62. (Pubitemid 28177265)
    • (1998) Critical Reviews in Neurobiology , vol.12 , Issue.1-2 , pp. 129-162
    • Hall, F.S.1
  • 25
    • 0035875146 scopus 로고    scopus 로고
    • The role of childhood trauma in the neurobiology of mood and anxiety disorders: Preclinical and clinical studies
    • DOI 10.1016/S0006-3223(01)01157-X, PII S000632230101157X
    • Heim C, Nemeroff CB. The role of childhood trauma in the neurobiology of mood and anxiety disorders: preclinical and clinical studies. Biol Psychiatry 2001;49:1023-39. (Pubitemid 32595461)
    • (2001) Biological Psychiatry , vol.49 , Issue.12 , pp. 1023-1039
    • Heim, C.1    Nemeroff, C.B.2
  • 26
    • 0036024262 scopus 로고    scopus 로고
    • Subchronic treatment with lithium increases nerve growth factor content in distinct brain regions of adult rats
    • Hellweg R, Lang UE,Nagel M, BaumgartnerA. Subchronic treatment with lithium increases nerve growth factor content in distinct brain regions of adult rats. Mol Psychiatry 2002;7:604-8.
    • (2002) Mol Psychiatry , vol.7 , pp. 604-608
    • Hellweg, R.1    Lang, U.E.2    Nagel, M.3    Baumgartner, A.4
  • 27
    • 0034847984 scopus 로고    scopus 로고
    • Stress induced sickness behaviors: An alternative hypothesis for responses during maternal separation
    • Hennessy MB, Deak T, Schiml-Webb PA. Stress induced sickness behaviors: an alternative hypothesis for responses during maternal separation. Dev Psychobiol 2001;39:76-83.
    • (2001) Dev Psychobiol , vol.39 , pp. 76-83
    • Hennessy, M.B.1    Deak, T.2    Schiml-Webb, P.A.3
  • 28
    • 77049120148 scopus 로고    scopus 로고
    • Antidepressant-like effects of 3,60-disinapoyl sucrose on hippocampal neuronal plasticity and neurotrophic signal pathway in chronically mild stressed rats
    • Hu Y, Liao HB, Dai-Hong G, Liu P, Wang YY, Rahman K. Antidepressant-like effects of 3,60-disinapoyl sucrose on hippocampal neuronal plasticity and neurotrophic signal pathway in chronically mild stressed rats. Neurochem Int 2010;3:461-5.
    • (2010) Neurochem Int , vol.3 , pp. 461-465
    • Hu, Y.1    Liao, H.B.2    Dai-Hong, G.3    Liu, P.4    Wang, Y.Y.5    Rahman, K.6
  • 29
    • 0036202956 scopus 로고    scopus 로고
    • Decreased serum brain-derived neurotrophic factor levels in major depressed patients
    • DOI 10.1016/S0165-1781(02)00005-7, PII S0165178102000057
    • Karege F, Perret G, Bondolfi G, Schwald M, Bertschy G, Aubry JM. Decreased serum brain-derived neurotrophic factor levels in major depressed patients. Psychiatry Res 2002;15:143-8. (Pubitemid 34258493)
    • (2002) Psychiatry Research , vol.109 , Issue.2 , pp. 143-148
    • Karege, F.1    Perret, G.2    Bondolfi, G.3    Schwald, M.4    Bertschy, G.5    Aubry, J.-M.6
  • 30
    • 18944406852 scopus 로고    scopus 로고
    • Neurotrophin levels in postmortem brains of suicide victims and the effects of antemortem diagnosis and psychotropic drugs
    • DOI 10.1016/j.molbrainres.2004.12.020, PII S0169328X04006345
    • Karege F, Vaudan G, Schwald M, Perroud N, La Harpe R. Neurotrophin levels inpostmortem brains of suicide victims and the effects of antemortem diagnosis and psychotropic drugs. Brain Res Mol Brain Res 2005;136:29-37. (Pubitemid 40704606)
    • (2005) Molecular Brain Research , vol.136 , Issue.1-2 , pp. 29-37
    • Karege, F.1    Vaudan, G.2    Schwald, M.3    Perroud, N.4    La, H.R.5
  • 31
    • 34249057458 scopus 로고    scopus 로고
    • Antidepressant-like effect of lamotrigine in the mouse forced swimming test: Evidence for the involvement of the noradrenergic system
    • DOI 10.1016/j.ejphar.2007.03.003, PII S0014299907003391
    • Kaster MP, Raupp I, Binfaré RW, Andreatini R, Rodrigues AL. Antidepressant-like effect of lamotrigine in the mouse forced swimming test: evidence for the involvement of the noradrenergic system. Eur J Pharmacol 2007;565:119-24. (Pubitemid 46795482)
    • (2007) European Journal of Pharmacology , vol.565 , Issue.1-3 , pp. 119-124
    • Kaster, M.P.1    Raupp, I.2    Binfare, R.W.3    Andreatini, R.4    Rodrigues, A.L.S.5
  • 32
    • 0037237645 scopus 로고    scopus 로고
    • The emerging differential roles of GABAergic and antiglutamatergic agents in bipolar disorders
    • Ketter TA,Wang PW. The emerging differential roles of GABAergic and antiglutamatergic agents in bipolar disorders. J Clin Psychiatry 2003;64:15-20. (Pubitemid 36389867)
    • (2003) Journal of Clinical Psychiatry , vol.64 , Issue.SUPPL. 3 , pp. 15-20
    • Ketter, T.A.1    Wang, P.W.2
  • 33
    • 34249775474 scopus 로고    scopus 로고
    • Neonatal handling alters learning in adult male and female rats in a task-specific manner
    • DOI 10.1016/j.brainres.2007.03.081, PII S0006899307007676
    • Kosten TA, Lee HJ, Kim JJ. Neonatal handling alters learning in adult male and female rats in a task-specific manner. Brain Res 2007;18:144-53. (Pubitemid 46856337)
    • (2007) Brain Research , vol.1154 , Issue.1 , pp. 144-153
    • Kosten, T.A.1    Lee, H.J.2    Kim, J.J.3
  • 34
    • 0022900644 scopus 로고
    • Pharmacological studies on lamotrigine, a novel potential antiepileptic drug: II. Neurochemical studies on the mechanism of action
    • Leach MJ, Marden CM, Miller AA. Pharmacological studies on lamotrigine, a novel potential antiepileptic drug: II. Neurochemical studies on the mechanism of action. Epilepsia 1986;27:490-7. (Pubitemid 16026042)
    • (1986) Epilepsia , vol.27 , Issue.5 , pp. 490-497
    • Leach, M.J.1    Marden, C.M.2    Miller, A.A.3
  • 35
    • 0026304850 scopus 로고
    • Neurochemical and behavioral aspects of lamotrigine
    • Leach MJ, Baxter MG, Critchley MAE, et al. Neurochemical and behavioral aspects of lamotrigine. Epilepsia 1991;2:4-8.
    • (1991) Epilepsia , vol.2 , pp. 4-8
    • Leach, M.J.1    Baxter, M.G.2    Critchley, M.A.E.3
  • 36
    • 0023236055 scopus 로고
    • The nerve growth factor 35 years later
    • Levi-Montalcini R. The nerve growth factor 35 years later. Science 1987;237:1154-62. (Pubitemid 17124912)
    • (1987) Science , vol.237 , Issue.4819 , pp. 1154-1162
    • Levi-Montalcini, R.1
  • 37
    • 82255183246 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor signaling mediates antidepressant effects of lamotrigine
    • Li N, He X, Zhang Y, Qi X, Li H, Zhu X, et al. Brain-derived neurotrophic factor signaling mediates antidepressant effects of lamotrigine. Int Neuropsychopharmacol 2010;16:1-8.
    • (2010) Int Neuropsychopharmacol , vol.16 , pp. 1-8
    • Li, N.1    He, X.2    Zhang, Y.3    Qi, X.4    Li, H.5    Zhu, X.6
  • 40
    • 69249210972 scopus 로고    scopus 로고
    • Physical exercise can reverse the deficit in fear memory induced by maternal deprivation
    • Mello PB. Physical exercise can reverse the deficit in fear memory induced by maternal deprivation. Neurobiol Learn Mem 2009;92:364-9.
    • (2009) Neurobiol Learn Mem , vol.92 , pp. 364-369
    • Mello, P.B.1
  • 42
    • 0028815653 scopus 로고
    • Regulation of BDNF and trkB mRNA in rat brain by chronic electroconvulsive seizure and antidepressant drug treatments
    • Nibuya M, Morinobu S, Duman RS. Regulation of BDNF and trkB mRNA in rat brain by chronic electroconvulsive seizure and antidepressant drug treatments. J Neurosci 1995;15:7539-47.
    • (1995) J Neurosci , vol.15 , pp. 7539-7547
    • Nibuya, M.1    Morinobu, S.2    Duman, R.S.3
  • 43
    • 0035163962 scopus 로고    scopus 로고
    • Selective serotonin-reuptake inhibitor antidepressants increase the risk of falls and hip fractures in elderly people by inhibiting cardiovascular ion channels
    • DOI 10.1054/mehy.2001.1366
    • Pacher P, Ungvari Z. Selective serotonin-reuptake inhibitor antidepressants increase the risk of falls and hip fractures in elderly people by inhibiting cardiovascular ion channels. Med Hypotheses 2001;57:469-71. (Pubitemid 33052038)
    • (2001) Medical Hypotheses , vol.57 , Issue.4 , pp. 469-471
    • Pacher, P.1    Ungvari, Z.2
  • 44
    • 32844469435 scopus 로고    scopus 로고
    • The primate amygdala represents the positive and negative value of visual stimuli during learning
    • DOI 10.1038/nature04490, PII NATURE04490
    • Paton JJ, Belova MA, Morrison SE, Salzman CD. The primate amygdala represents the positive and negative value of visual stimuli during learning. Nature 2006;439: 865-70. (Pubitemid 43255706)
    • (2006) Nature , vol.439 , Issue.7078 , pp. 865-870
    • Paton, J.J.1    Belova, M.A.2    Morrison, S.E.3    Salzman, C.D.4
  • 46
    • 24744453295 scopus 로고    scopus 로고
    • Amygdalar and prefrontal pathways to the lateral hypothalamus are activated by a learned cue that stimulates eating
    • DOI 10.1523/JNEUROSCI.2480-05.2005
    • Petrovich GD, Holland PC, Gallagher M. Amygdalar and prefrontal pathways to the lateral hypothalamus are activated by a learned cue that stimulates eating. J Neurosci 2005;25:8295-302. (Pubitemid 41292124)
    • (2005) Journal of Neuroscience , vol.25 , Issue.36 , pp. 8295-8302
    • Petrovich, G.D.1    Holland, P.C.2    Gallagher, M.3
  • 48
    • 77449095540 scopus 로고    scopus 로고
    • Mood-stabilizers target the brain arachidonic acid cascade
    • Rao JS, Rapoport SI. Mood-stabilizers target the brain arachidonic acid cascade. Curr Mol Pharmacol 2009;2:207-14.
    • (2009) Curr Mol Pharmacol , vol.2 , pp. 207-214
    • Rao, J.S.1    Rapoport, S.I.2
  • 49
    • 77049122009 scopus 로고    scopus 로고
    • Neurochemical and behavioural effects of acute and chronic memantine administration in rats: Further support for NMDA as a new pharmacological target for the treatment of depression?
    • Réus GZ, Stringari RB, Kirsch TR, Fries GR, Kapczinski F, Roesler R, et al. Neurochemical and behavioural effects of acute and chronic memantine administration in rats: Further support for NMDA as a new pharmacological target for the treatment of depression? Brain Res Bull 2010;816:585-9.
    • (2010) Brain Res Bull , vol.816 , pp. 585-589
    • Réus, G.Z.1    Stringari, R.B.2    Kirsch, T.R.3    Fries, G.R.4    Kapczinski, F.5    Roesler, R.6
  • 50
    • 79953070155 scopus 로고    scopus 로고
    • Ketamine plus imipramine treatment induces antidepressant-like behavior and increases CREB and BDNF protein levels and PKA and PKC phosphorylation in rat brain
    • Réus GZ, Stringari RB, Ribeiro KF, Ferraro AK, Vitto MF, Cesconetto P, et al. Ketamine plus imipramine treatment induces antidepressant-like behavior and increases CREB and BDNF protein levels and PKA and PKC phosphorylation in rat brain. Behav Brain Res 2011a;221:166-71.
    • (2011) Behav Brain Res , vol.221 , pp. 166-171
    • Réus, G.Z.1    Stringari, R.B.2    Ribeiro, K.F.3    Ferraro, A.K.4    Vitto, M.F.5    Cesconetto, P.6
  • 51
  • 52
    • 61849083112 scopus 로고    scopus 로고
    • Future antidepressant targets: Neurotrophic factors and related signaling cascades
    • Schmidt HD, Banasr M, Duman RS. Future antidepressant targets: neurotrophic factors and related signaling cascades. Drug Discov today ther Strateg 2008;53:151-6.
    • (2008) Drug Discov Today Ther Strateg , vol.53 , pp. 151-156
    • Schmidt, H.D.1    Banasr, M.2    Duman, R.S.3
  • 53
    • 33750813311 scopus 로고    scopus 로고
    • Differential regulation of nerve growth factor and brain-derived neurotrophic factor in a mouse model of learned helplessness
    • DOI 10.1016/j.expneurol.2006.07.002, PII S0014488606004006
    • Schulte-Herbrüggen O, Chourbaji S, Müller H, Danker-Hopfe H, Brandwein C, Gass P, et al. Differential regulation of nerve growth factor and brain-derived neurotrophic factor in a mouse model of learned helplessness. Exp Neurol 2006;202:404-9. (Pubitemid 44711900)
    • (2006) Experimental Neurology , vol.202 , Issue.2 , pp. 404-409
    • Schulte-Herbruggen, O.1    Chourbaji, S.2    Muller, H.3    Danker-Hopfe, H.4    Brandwein, C.5    Gass, P.6    Hellweg, R.7
  • 54
    • 70349250240 scopus 로고    scopus 로고
    • Effects of escitalopram on the regulation of brain-derived neurotrophic factor and nerve growth factor protein levels in a rat model of chronic stress
    • Schulte-Herbrüggen O, Fuchs E, Abumaria N, Ziegler A, Danker-Hopfe H, Hiemke C, et al. Effects of escitalopram on the regulation of brain-derived neurotrophic factor and nerve growth factor protein levels in a rat model of chronic stress. J Neurosci Res 2009;8711:2551-60.
    • (2009) J Neurosci Res , vol.8711 , pp. 2551-2560
    • Schulte-Herbrüggen, O.1    Fuchs, E.2    Abumaria, N.3    Ziegler, A.4    Danker-Hopfe, H.5    Hiemke, C.6
  • 55
    • 0032080046 scopus 로고    scopus 로고
    • Effects of lamotrigine on the 5-HT(1A) receptor function in healthy human males
    • DOI 10.1016/S0165-0327(98)00008-1, PII S0165032798000081
    • Shiah IS, Yatham LN, Lam RW, Zis AP. Effects of lamotrigine on the 5-HT1A receptor function in healthy human males. J Affect Disord 1998;49:157-62. (Pubitemid 28202007)
    • (1998) Journal of Affective Disorders , vol.49 , Issue.2 , pp. 157-162
    • Shiah, I.-S.1    Yatham, L.N.2    Lam, R.W.3    Zis, A.P.4
  • 56
    • 0032566653 scopus 로고    scopus 로고
    • Lamotrigine inhibits monoamine uptake in vitro and modulates 5-hydroxytryptamine uptake in rats
    • DOI 10.1016/S0014-2999(98)00580-9, PII S0014299998005809
    • Southam E, Kirby D, Higgins GA, Hagan RM. Lamotrigine inhibits monoamine uptake in vitro and modulates 5-hydroxytryptamine uptake in rats. Eur J Pharmacol 1998;358:19-24. (Pubitemid 28464464)
    • (1998) European Journal of Pharmacology , vol.358 , Issue.1 , pp. 19-24
    • Southam, E.1    Kirkby, D.2    Higgins, G.A.3    Hagan, R.M.4
  • 57
    • 77950810570 scopus 로고    scopus 로고
    • Systematic review of lamotrigine augmentation of treatment resistant unipolar depression (TRD)
    • Thomas SP, Nandhra HS, Jayaraman A. Systematic review of lamotrigine augmentation of treatment resistant unipolar depression (TRD). J Ment Health 2010;2:168-75.
    • (2010) J Ment Health , vol.2 , pp. 168-175
    • Thomas, S.P.1    Nandhra, H.S.2    Jayaraman, A.3
  • 58
    • 79959197428 scopus 로고    scopus 로고
    • Roles of glutamate signaling in preclinical and/ormechanistic models of depression
    • 11320000/s01787728
    • Tokita K, Yamaji T, Hashimoto K. Roles of glutamate signaling in preclinical and/ormechanistic models of depression. Pharmacol Biochem Behav 2011. 11320000/s01787728.
    • (2011) Pharmacol Biochem Behav
    • Tokita, K.1    Yamaji, T.2    Hashimoto, K.3
  • 59
    • 34447130850 scopus 로고    scopus 로고
    • Regulation of adult hippocampal neurogenesis: Relevance to depression
    • DOI 10.1586/14737175.7.7.853
    • Vaidya VA, Fernandes K, Jha S. Regulation of adult hippocampal neurogenesis: relevance to depression. Expert Rev Neurother 2007;7:853-64. (Pubitemid 47037725)
    • (2007) Expert Review of Neurotherapeutics , vol.7 , Issue.7 , pp. 853-864
    • Vaidya, V.A.1    Fernandes, K.2    Jha, S.3
  • 60
    • 68649123338 scopus 로고    scopus 로고
    • Anticonvulsants in the treatment of major depressive disorder: An overview
    • Vigo DV, Baldessarini RJ. Anticonvulsants in the treatment of major depressive disorder: an overview. Harv Rev Psychiatry 2009;17:231-41.
    • (2009) Harv Rev Psychiatry , vol.17 , pp. 231-241
    • Vigo, D.V.1    Baldessarini, R.J.2
  • 61
    • 0142134103 scopus 로고    scopus 로고
    • Effects of different kinds of acute stress on nerve growth factor content in rat brain
    • DOI 10.1016/S0006-8993(03)03338-9
    • von Richthofen S, Lang UE, Hellweg R. Effects of different kinds of acute stress on nerve growth factor content in rat brain. Brain Res 2003;987:207-13. (Pubitemid 37281435)
    • (2003) Brain Research , vol.987 , Issue.2 , pp. 207-213
    • Von Richthofen, S.1    Lang, U.E.2    Hellweg, R.3
  • 62
    • 0029432189 scopus 로고
    • Similar potency of carbamazepine, oxcarbazepine, and lamotrigine in inhibiting the release of glutamate and other neurotransmitters
    • Waldmeier PC, Baumann PA, Wicki P, Feldtrauer JJ, Stierlin C, Schmutz M. Similar potency of carbamazepine, oxcarbazepine an lamotrigine in inhibiting the release of glutamate and others neurotransmitters. Neurology 1996;45:1907-13. (Pubitemid 27122967)
    • (1995) Neurology , vol.45 , Issue.10 , pp. 1907-1913
    • Waldmeier, P.C.1    Baumann, P.A.2    Wicki, P.3    Feldtrauer, J.-J.4    Stierlin, C.5    Schmutz, M.6
  • 63
    • 0036193802 scopus 로고    scopus 로고
    • Lamotrigine increases gene expression of GABA-A receptor 3 subunit in primary cultured rat hippocampus cells
    • DOI 10.1016/S0893-133X(01)00385-2, PII S0893133X01003852
    • Wang JF, Sun X, Chen B, Young LT. Lamotrigine increase gene expression of GABA-A receptor 3 subunit in primary cultured rat hippocampus cells. Neuropsychopharmacol 2002;26: 415-21. (Pubitemid 34260991)
    • (2002) Neuropsychopharmacology , vol.26 , Issue.4 , pp. 415-421
    • Wang, J.-F.1    Sun, X.2    Chen, B.3    Young, L.T.4
  • 64
    • 0035748591 scopus 로고    scopus 로고
    • The pharmacogenomics of depression
    • Wong ML, Licinio J. The pharmacogenomics of depression. Pharmacogenomics J 2001;13:175-7. (Pubitemid 33756656)
    • (2001) Pharmacogenomics Journal , vol.1 , Issue.3 , pp. 175-177
    • Licinio, J.1


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