-
1
-
-
13344285339
-
Identification and characterization of a new member of the TNF family that induces apoptosis
-
DOI 10.1016/1074-7613(95)90057-8
-
Wiley, SR, Schooley, K, Smolak, PJ, Din, WS, Huang, CP, Nicholl, JK et al. (1995). Identification and characterization of a new member of the TNF family that induces apoptosis. Immunity 3: 673-682. (Pubitemid 26091143)
-
(1995)
Immunity
, vol.3
, Issue.6
, pp. 673-682
-
-
Wiley, S.R.1
Schooley, K.2
Smolak, P.J.3
Din, W.S.4
Huang, C.-P.5
Nicholl, J.K.6
Sutherland, G.R.7
Smith, T.D.8
Rauch, C.9
Smith, C.A.10
Goodwin, R.G.11
-
2
-
-
0032713075
-
Safety and antitumor activity of recombinant soluble Apo2 ligand
-
Ashkenazi, A, Pai, RC, Fong, S, Leung, S, Lawrence, DA, Marsters, SA et al. (1999). Safety and antitumor activity of recombinant soluble Apo2 ligand. J Clin Invest 104: 155-162.
-
(1999)
J Clin Invest
, vol.104
, pp. 155-162
-
-
Ashkenazi, A.1
Pai, R.C.2
Fong, S.3
Leung, S.4
Lawrence, D.A.5
Marsters, S.A.6
-
3
-
-
0032929520
-
Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo
-
DOI 10.1038/5517
-
Walczak, H, Miller, RE, Ariail, K, Gliniak, B, Griffith, TS, Kubin, M et al. (1999). Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo. Nat Med 5: 157-163. (Pubitemid 29068521)
-
(1999)
Nature Medicine
, vol.5
, Issue.2
, pp. 157-163
-
-
Walczak, H.1
Miller, R.E.2
Ariail, K.3
Gliniak, B.4
Griffith, T.S.5
Kubin, M.6
Chin, W.7
Jones, J.8
Woodward, A.9
Le, T.10
Smith, C.11
Smolak, P.12
Goodwin, R.G.13
Rauch, C.T.14
Schuh, J.C.L.15
Lynch, D.H.16
-
4
-
-
62449168519
-
TRAIL agonists on clinical trials for cancer therapy: The promises and the challenges
-
Bellail, AC, Qi, L, Mulligan, P, Chhabra, V and Hao, C (2009). TRAIL agonists on clinical trials for cancer therapy: the promises and the challenges. Rev Recent Clin Trials 4: 34-41.
-
(2009)
Rev Recent Clin Trials
, vol.4
, pp. 34-41
-
-
Bellail, A.C.1
Qi, L.2
Mulligan, P.3
Chhabra, V.4
Hao, C.5
-
5
-
-
77649301860
-
Phase i trial of weekly tigatuzumab, an agonistic humanized monoclonal antibody targeting death receptor 5 (DR5)
-
Forero-Torres, A, Shah, J, Wood, T, Posey, J, Carlisle, R, Copigneaux, C et al. (2010). Phase I trial of weekly tigatuzumab, an agonistic humanized monoclonal antibody targeting death receptor 5 (DR5). Cancer Biother Radiopharm 25: 13-19.
-
(2010)
Cancer Biother Radiopharm
, vol.25
, pp. 13-19
-
-
Forero-Torres, A.1
Shah, J.2
Wood, T.3
Posey, J.4
Carlisle, R.5
Copigneaux, C.6
-
6
-
-
29644444314
-
A novel anti-human DR5 monoclonal antibody with tumoricidal activity induces caspase-dependent and caspase-independent cell death
-
DOI 10.1074/jbc.M503621200
-
Guo, Y, Chen, C, Zheng, Y, Zhang, J, Tao, X, Liu, S et al. (2005). A novel anti-human DR5 monoclonal antibody with tumoricidal activity induces caspase-dependent and caspase-independent cell death. J Biol Chem 280: 41940-41952. (Pubitemid 43023163)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.51
, pp. 41940-41952
-
-
Guo, Y.1
Chen, C.2
Zheng, Y.3
Zhang, J.4
Tao, X.5
Liu, S.6
Zheng, D.7
Liu, Y.8
-
7
-
-
77950550872
-
Targeting a novel N-terminal epitope of death receptor 5 triggers tumor cell death
-
Zhang, P, Zheng, Y, Shi, J, Zhang, Y, Liu, S, Liu, Y et al. (2010). Targeting a novel N-terminal epitope of death receptor 5 triggers tumor cell death. J Biol Chem 285: 8953-8966.
-
(2010)
J Biol Chem
, vol.285
, pp. 8953-8966
-
-
Zhang, P.1
Zheng, Y.2
Shi, J.3
Zhang, Y.4
Liu, S.5
Liu, Y.6
-
8
-
-
33646352962
-
Potent antibody therapeutics by design
-
Carter, PJ (2006). Potent antibody therapeutics by design. Nat Rev Immunol 6: 343-357.
-
(2006)
Nat Rev Immunol
, vol.6
, pp. 343-357
-
-
Carter, P.J.1
-
9
-
-
33846260583
-
Therapeutic expression of an anti-death receptor 5 single-chain fixed-variable region prevents tumor growth in mice
-
DOI 10.1158/0008-5472.CAN-06-1227
-
Shi, J, Liu, Y, Zheng, Y, Guo, Y, Zhang, J, Cheung, PT et al. (2006). Therapeutic expression of an anti-death receptor 5 single-chain fixed-variable region prevents tumor growth in mice. Cancer Res 66: 11946-11953. (Pubitemid 46094208)
-
(2006)
Cancer Research
, vol.66
, Issue.24
, pp. 11946-11953
-
-
Shi, J.1
Liu, Y.2
Zheng, Y.3
Guo, Y.4
Zhang, J.5
Cheung, P.-T.6
Xu, R.7
Zheng, D.8
-
10
-
-
22744444388
-
Stable antibody expression at therapeutic levels using the 2A peptide
-
DOI 10.1038/nbt1087
-
Fang, J, Qian, JJ, Yi, S, Harding, TC, Tu, GH, VanRoey, M et al. (2005). Stable antibody expression at therapeutic levels using the 2A peptide. Nat Biotechnol 23: 584-590. (Pubitemid 41724897)
-
(2005)
Nature Biotechnology
, vol.23
, Issue.5
, pp. 584-590
-
-
Fang, J.1
Qian, J.-J.2
Yi, S.3
Harding, T.C.4
Tu, G.H.5
VanRoey, M.6
Jooss, K.7
-
11
-
-
84869856152
-
Expression and tumoricidal activity of a human-mouse chimeric anti-DR5 antibody through a Furin/2A peptide
-
[Chinese]
-
Li, M, Lu, FJ, Shi, J, Liu, YX and Zheng, DX (2011). Expression and tumoricidal activity of a human-mouse chimeric anti-DR5 antibody through a Furin/2A peptide. Zonghua Yi Xue Za Zhi 91: 707-710. [Chinese].
-
(2011)
Zonghua Yi Xue Za Zhi
, vol.91
, pp. 707-710
-
-
Li, M.1
Lu, F.J.2
Shi, J.3
Liu, Y.X.4
Zheng, D.X.5
-
12
-
-
16444381759
-
Overexpression of soluble TRAIL induces apoptosis in human lung adenocarcinoma and inhibits growth of tumor xenografts in nude mice
-
DOI 10.1158/0008-5472.CAN-04-2749
-
Shi, J, Zheng, D, Liu, Y, Sham, MH, Tam, P, Farzaneh, F et al. (2005). Overexpression of soluble TRAIL induces apoptosis in human lung adenocarcinoma and inhibits growth of tumor xenografts in nude mice. Cancer Res 65: 1687-1692. (Pubitemid 40478593)
-
(2005)
Cancer Research
, vol.65
, Issue.5
, pp. 1687-1692
-
-
Shi, J.1
Zheng, D.2
Liu, Y.3
Mai, H.S.4
Tam, P.5
Farzaneh, F.6
Xu, R.7
-
13
-
-
1642443440
-
Monoclonal antibodies produced by muscle after plasmid injection and electroporation
-
DOI 10.1016/j.ymthe.2003.12.007
-
Tjelle, TE, Corthay, A, Lunde, E, Sandlie, I, Michaelsen, TE, Mathiesen, I et al. (2004). Monoclonal antibodies produced by muscle after plasmid injection and electroporation. Mol Ther 9: 328-336. (Pubitemid 38404521)
-
(2004)
Molecular Therapy
, vol.9
, Issue.3
, pp. 328-336
-
-
Tjelle, T.E.1
Corthay, A.2
Lunde, E.3
Sandlie, I.4
Michaelsen, T.E.5
Mathiesen, I.6
Bogen, B.7
-
14
-
-
58349088481
-
Growth inhibition of an established A431 xenograft tumor by a full-length anti-EGFR antibody following gene delivery by AAV
-
Ho, DT, Wykoff-Clary, S, Gross, CS, Schneider, D, Jin, F, Kretschmer, PJ et al. (2009). Growth inhibition of an established A431 xenograft tumor by a full-length anti-EGFR antibody following gene delivery by AAV. Cancer Gene Ther 16: 184-194.
-
(2009)
Cancer Gene Ther
, vol.16
, pp. 184-194
-
-
Ho, D.T.1
Wykoff-Clary, S.2
Gross, C.S.3
Schneider, D.4
Jin, F.5
Kretschmer, P.J.6
-
15
-
-
77954819051
-
Persistent expression of biologically active anti-HER2 antibody by AAVrh.10-mediated gene transfer
-
Wang, G, Qiu, J, Wang, R, Krause, A, Boyer, JL, Hackett, NR et al. (2010). Persistent expression of biologically active anti-HER2 antibody by AAVrh.10-mediated gene transfer. Cancer Gene Ther 17: 559-570.
-
(2010)
Cancer Gene Ther
, vol.17
, pp. 559-570
-
-
Wang, G.1
Qiu, J.2
Wang, R.3
Krause, A.4
Boyer, J.L.5
Hackett, N.R.6
-
16
-
-
0034170820
-
IRESdependent second gene expression is significantly lower than cap-dependent first gene expression in a bicistronic vector
-
Mizuguchi, H, Xu, Z, Ishii-Watabe, A, Uchida, E and Hayakawa, T (2000). IRESdependent second gene expression is significantly lower than cap-dependent first gene expression in a bicistronic vector. Mol Ther 1: 376-382.
-
(2000)
Mol Ther
, vol.1
, pp. 376-382
-
-
Mizuguchi, H.1
Xu, Z.2
Ishii-Watabe, A.3
Uchida, E.4
Hayakawa, T.5
-
17
-
-
15944367464
-
Design and manufacture of monoclonal antibodies for radioimmunotherapy
-
Hale, G, Berrie, E and Bird, P (2004). Design and manufacture of monoclonal antibodies for radioimmunotherapy. Q J Nucl Med Mol Imaging 48: 258-266. (Pubitemid 43932935)
-
(2004)
Quarterly Journal of Nuclear Medicine and Molecular Imaging
, vol.48
, Issue.4
, pp. 258-266
-
-
Hale, G.1
Berrie, E.2
Bird, P.3
-
18
-
-
34249289748
-
An antibody delivery system for regulated expression of therapeutic levels of monoclonal antibodies In Vivo
-
DOI 10.1038/sj.mt.6300142, PII 6300142
-
Fang, J, Yi, S, Simmons, A, Tu, GH, Nguyen, M, Harding, TC et al. (2007). An antibody delivery system for regulated expression of therapeutic levels of monoclonal antibodies in vivo. Mol Ther 15: 1153-1159. (Pubitemid 46813618)
-
(2007)
Molecular Therapy
, vol.15
, Issue.6
, pp. 1153-1159
-
-
Fang, J.1
Yi, S.2
Simmons, A.3
Tu, G.H.4
Nguyen, M.5
Harding, T.C.6
VanRoey, M.7
Jooss, K.8
-
19
-
-
0029993858
-
Efficient transfer, integration, and sustained long-term expression of the transgene in adult rat brains injected with a lentiviral vector
-
DOI 10.1073/pnas.93.21.11382
-
Naldini, L, Bler, U, Gage, FH, Trono, D and Verma, IM (1996). Efficient transfer, integration, and sustained long-term expression of the transgene in adult rat brains injected with a lentiviral vector. Proc Natl Acad Sci USA 93: 11382-11388. (Pubitemid 26347130)
-
(1996)
Proceedings of the National Academy of Sciences of the United States of America
, vol.93
, Issue.21
, pp. 11382-11388
-
-
Naldini, L.1
Blomer, U.2
Gage, F.H.3
Trono, D.4
Verma, I.M.5
-
20
-
-
0030716959
-
Sustained expression of genes delivered directly into liver and muscle by lentiviral vectors
-
DOI 10.1038/ng1197-314
-
Kafri, T, Bler, U, Peterson, DA, Gage, FH and Verma, IM (1997). Sustained expression of genes delivered directly into liver and muscle by lentiviral vectors. Nat Genet 17: 314-317. (Pubitemid 27475995)
-
(1997)
Nature Genetics
, vol.17
, Issue.3
, pp. 314-317
-
-
Kafri, T.1
Blomer, U.2
Peterson, D.A.3
Gage, F.H.4
Verma, I.M.5
-
21
-
-
0029996147
-
In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector
-
Naldini, L, Bler, U, Gallay, P, Ory, D, Mulligan, R, Gage, FH et al. (1996). In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector. Science 272: 263-267. (Pubitemid 26119138)
-
(1996)
Science
, vol.272
, Issue.5259
, pp. 263-267
-
-
Naldini, L.1
Blomer, U.2
Gallay, P.3
Ory, D.4
Mulligan, R.5
Gage, F.H.6
Verma, I.M.7
Trono, D.8
-
22
-
-
28844484109
-
Potential of mesenchymal stem cells in gene therapy approaches for inherited and acquired diseases
-
DOI 10.1517/14712598.5.12.1571
-
Reiser, J, Zhang, XY, Hemenway, CS, Mondal, D, Pradhan, L and La Russa, VF (2005). Potential of mesenchymal stem cells in gene therapy approaches for inherited and acquired diseases. Expert Opin Biol Ther 5: 1571-1584. (Pubitemid 41771848)
-
(2005)
Expert Opinion on Biological Therapy
, vol.5
, Issue.12
, pp. 1571-1584
-
-
Reiser, J.1
Zhang, X.-Y.2
Hemenway, C.S.3
Mondal, D.4
Pradhan, L.5
La Russa, V.F.6
-
23
-
-
34249034598
-
Tumor therapy mediated by lentiviral expression of shBcl-2 and S-TRAIL1
-
DOI 10.1593/neo.07223
-
Kock, N, Kasmieh, R, Weissleder, R and Shah, K (2007). Tumor therapy mediated by lentiviral expression of shBcl-2 and S-TRAIL. Neoplasia 9: 435-442. (Pubitemid 46799987)
-
(2007)
Neoplasia
, vol.9
, Issue.5
, pp. 435-442
-
-
Kock, N.1
Kasmieh, R.2
Weissledery, R.3
Shah, K.4
-
24
-
-
38349059202
-
Treatment of pulmonary metastatic tumors in mice using lentiviral vector-engineered stem cells
-
Zhang, X, Zhao, P, Kennedy, C, Chen, K, Wiegand, J, Washington, G et al. (2008). Treatment of pulmonary metastatic tumors in mice using lentiviral vector-engineered stem cells. Cancer Gene Ther 15: 73-84.
-
(2008)
Cancer Gene Ther
, vol.15
, pp. 73-84
-
-
Zhang, X.1
Zhao, P.2
Kennedy, C.3
Chen, K.4
Wiegand, J.5
Washington, G.6
-
25
-
-
34247534059
-
The therapeutic potential of hepatocyte growth factor to sensitize ovarian cancer cells to cisplatin and paclitaxel in vivo
-
DOI 10.1158/1078-0432.CCR-06-1915
-
Bardella, C, Dettori, D, Olivero, M, Coltella, N, Mazzone, M and Di Renzo, MF (2007). The therapeutic potential of hepatocyte growth factor to sensitize ovarian cancer cells to cisplatin and paclitaxel in vivo. Clin Cancer Res 13: 2191-2198. (Pubitemid 46649889)
-
(2007)
Clinical Cancer Research
, vol.13
, Issue.7
, pp. 2191-2198
-
-
Bardella, C.1
Dettori, D.2
Olivero, M.3
Coltella, N.4
Mazzone, M.5
Di Renzo, M.F.6
-
26
-
-
78449311112
-
Gene therapy augments the efficacy of hematopoietic cell transplantation and fully corrects mucopolysaccharidosis type i phenotype in the mouse model
-
Visigalli, I, Delai, S, Politi, LS, Di Domenico, C, Cerri, F, Mrak, E et al. (2010). Gene therapy augments the efficacy of hematopoietic cell transplantation and fully corrects mucopolysaccharidosis type I phenotype in the mouse model. Blood 116: 5130-5139.
-
(2010)
Blood
, vol.116
, pp. 5130-5139
-
-
Visigalli, I.1
Delai, S.2
Politi, L.S.3
Di Domenico, C.4
Cerri, F.5
Mrak, E.6
-
27
-
-
70349492116
-
Stabilization of gammaretroviral and lentiviral vectors: From production to gene transfer
-
Carmo, M, Alves, A, Rodrigues, AF, Coroadinha, AS, Carrondo, MJ, Alves, PM et al. (2009). Stabilization of gammaretroviral and lentiviral vectors: from production to gene transfer. J Gene Med 11: 670-678.
-
(2009)
J Gene Med
, vol.11
, pp. 670-678
-
-
Carmo, M.1
Alves, A.2
Rodrigues, A.F.3
Coroadinha, A.S.4
Carrondo, M.J.5
Alves, P.M.6
-
28
-
-
0035192884
-
FLICE-inhibitory proteins: Regulators of death receptor-mediated apoptosis
-
DOI 10.1128/MCB.21.24.8247-8254.2001
-
Krueger, A, Baumann, S, Krammer, PH and Kirchhoff, S (2001). FLICE-inhibitory proteins: regulators of death receptor-mediated apoptosis. Mol Cell Biol 21: 8247-8254. (Pubitemid 33108586)
-
(2001)
Molecular and Cellular Biology
, vol.21
, Issue.24
, pp. 8247-8254
-
-
Krueger, A.1
Baumann, S.2
Krammer, P.H.3
Kirchhoff, S.4
-
29
-
-
36048982462
-
Smac mimetics and TNFα: A dangerous liaison?
-
DOI 10.1016/j.cell.2007.10.042, PII S0092867407013967
-
Wu, H, Tschopp, J and Lin, SC (2007). Smac mimetics and TNFalpha: a dangerous liaisonÁ Cell 131: 655-658. (Pubitemid 350087206)
-
(2007)
Cell
, vol.131
, Issue.4
, pp. 655-658
-
-
Wu, H.1
Tschopp, J.2
Lin, S.-C.3
|