Targeting a novel N-terminal epitope of death receptor 5 triggers tumor cell death

Journal of Biological Chemistry

Volumn 285, Issue 12, 2010, Pages 8953-8966

  Zhang, Peng ^a   Zheng, Yong ^b   Shi, Juan ^a   Zhang, Yaxi ^a   Liu, Shilian ^a   Liu, Yanxin ^a   Zheng, Dexian ^a  

^a INSTITUTE OF BASIC MEDICAL SCIENCES   (China)

^b MOUNT SINAI HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOSIS; APOPTOTIC; CANCER CELLS; CANCER IMMUNOTHERAPY; CANCER THERAPY; CASPASE ACTIVATION; CYSTEINE-RICH DOMAINS; DEATH-RECEPTOR; EXTRACELLULAR; EXTRACELLULAR DOMAINS; FUNCTIONAL DOMAINS; HIGH AFFINITY; LIGAND ASSEMBLIES; N-TERMINALS; NEW STRATEGY; PEPTIDE ARRAYS; PERMUTATION ANALYSIS; RECEPTOR COMPLEX; TARGET SITES; TIME-DEPENDENT; TUMOR CELLS; TUMOR NECROSIS FACTOR-RELATED APOPTOSIS-INDUCING LIGANDS; WILD TYPES;

ALLERGIES; COMPLEXATION; GLYCOPROTEINS; LIGANDS; MACROPHAGES; MERGERS AND ACQUISITIONS; MONOCLONAL ANTIBODIES; STRATEGIC PLANNING; SURFACE PLASMON RESONANCE; TUMORS;

CELL DEATH;

CASPASE; DEATH RECEPTOR 5; EPITOPE; LEUCINE; MONOCLONAL ANTIBODY; RECOMBINANT PROTEIN; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND RECEPTOR;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; APOPTOSIS; ARTICLE; BINDING AFFINITY; BINDING SITE; CELL DEATH; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; GENE ACTIVATION; GENE FUNCTION; HUMAN; HUMAN CELL; IMMUNOGENICITY; IMMUNOPRECIPITATION; IMMUNOREACTIVITY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN DETERMINATION; PROTEIN DOMAIN; PROTEIN INTERACTION; SIGNAL TRANSDUCTION; TUMOR CELL; CELL MEMBRANE; CELL SURVIVAL; CHEMISTRY; COMPUTER PROGRAM; HELA CELL; LEUKEMIA CELL LINE; METABOLISM; NEOPLASM; PROTEIN TERTIARY STRUCTURE; TUMOR CELL LINE;

ANTIBODIES, MONOCLONAL; CELL DEATH; CELL LINE, TUMOR; CELL MEMBRANE; CELL SURVIVAL; EPITOPES; HELA CELLS; HUMANS; JURKAT CELLS; LEUCINE; NEOPLASMS; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, TNF-RELATED APOPTOSIS-INDUCING LIGAND; RECOMBINANT PROTEINS; SOFTWARE; TNF-RELATED APOPTOSIS-INDUCING LIGAND;

EID: 77950550872     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.070680     Document Type: Article

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