메뉴 건너뛰기




Volumn 10, Issue 1, 2012, Pages 24-29

Association between tacrolimus concentration and genetic polymorphisms of CYP3A5 and ABCB1 during the early stage after liver transplant in an Iranian population

Author keywords

Ethnicity; Immunosuppressive drugs; Organ; Pharmacogenetics; Transplant

Indexed keywords

CYCLOSPORIN; CYTOCHROME P450 3A5; GLYCOPROTEIN P; MULTIDRUG RESISTANCE PROTEIN 1; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; STEROID; TACROLIMUS;

EID: 84856912037     PISSN: 13040855     EISSN: None     Source Type: Journal    
DOI: 10.6002/ect.2011.0093     Document Type: Article
Times cited : (17)

References (38)
  • 1
    • 0038237028 scopus 로고    scopus 로고
    • Tacrolimus: A further update of its use in the management of organ transplantation
    • Scott LJ, McKeage K, Keam SJ, Plosker GL. Tacrolimus: a further update of its use in the management of organ transplantation. Drugs. 2003;63(12):1247-1297.
    • (2003) Drugs. , vol.63 , Issue.12 , pp. 1247-1297
    • Scott, L.J.1    McKeage, K.2    Keam, S.J.3    Plosker, G.L.4
  • 2
    • 0041831261 scopus 로고    scopus 로고
    • Genetic polymorphisms of the CYP3A4, CYP3A5, and MDR-1 genes and pharmacokinetics of the calcineurin inhibitors cyclosporine and tacrolimus
    • Hesselink DA, van Schaik RH, van der Heiden IP, et al. Genetic polymorphisms of the CYP3A4, CYP3A5, and MDR-1 genes and pharmacokinetics of the calcineurin inhibitors cyclosporine and tacrolimus. Clin Pharmacol Ther. 2003;74(3):245-254.
    • (2003) Clin Pharmacol Ther. , vol.74 , Issue.3 , pp. 245-254
    • Hesselink, D.A.1    van Schaik, R.H.2    van der Heiden, I.P.3
  • 3
    • 0242332169 scopus 로고    scopus 로고
    • Impact of cytochrome p450 3A5 genetic polymorphism on tacrolimus doses and concentration-to-dose ratio in renal transplant recipients
    • Thervet E, Anglicheau D, King B, Schlageter MH, et al. Impact of cytochrome p450 3A5 genetic polymorphism on tacrolimus doses and concentration-to-dose ratio in renal transplant recipients. Transplantation. 2003;76(8):1233-1235.
    • (2003) Transplantation. , vol.76 , Issue.8 , pp. 1233-1235
    • Thervet, E.1    Anglicheau, D.2    King, B.3    Schlageter, M.H.4
  • 4
    • 84879421187 scopus 로고    scopus 로고
    • US National Center for Biotechnology Information Web site. Available at: Accessed November 22, 2011
    • US National Center for Biotechnology Information Web site. Single nucleotide polymorphism. Available at: www.ncbi.nlm.nih.gov/ SNP/GeneGt. Accessed November 22, 2011.
    • Single nucleotide polymorphism
  • 5
    • 77249158801 scopus 로고    scopus 로고
    • Effect of CYP3A and ABCB1 single nucleotide polymorphisms on the pharmacokinetics and pharmacodynamics of calcineurin inhibitors: Part I
    • Staatz CE, Goodman LK, Tett SE. Effect of CYP3A and ABCB1 single nucleotide polymorphisms on the pharmacokinetics and pharmacodynamics of calcineurin inhibitors: Part I. Clin Pharmacokinet. 2010;49(3):141-175.
    • (2010) Clin Pharmacokinet. , vol.49 , Issue.3 , pp. 141-175
    • Staatz, C.E.1    Goodman, L.K.2    Tett, S.E.3
  • 6
    • 77249125964 scopus 로고    scopus 로고
    • Effect of CYP3A and ABCB1 single nucleotide polymorphisms on the pharmacokinetics and pharmacodynamics of calcineurin inhibitors: Part II
    • Staatz CE, Goodman LK, Tett SE. Effect of CYP3A and ABCB1 single nucleotide polymorphisms on the pharmacokinetics and pharmacodynamics of calcineurin inhibitors: Part II. Clin Pharmacokinet. 2010;49(4):207-221.
    • (2010) Clin Pharmacokinet. , vol.49 , Issue.4 , pp. 207-221
    • Staatz, C.E.1    Goodman, L.K.2    Tett, S.E.3
  • 7
    • 10744222684 scopus 로고    scopus 로고
    • Sequence diversity and haplotype structure in the human ABCB1 (MDR1, multidrug resistance transporter) gene
    • Kroetz DL, Pauli-Magnus C, Hodges LM, et al. Sequence diversity and haplotype structure in the human ABCB1 (MDR1, multidrug resistance transporter) gene. Pharmacogenetics. 2003;13(8):481-494.
    • (2003) Pharmacogenetics. , vol.13 , Issue.8 , pp. 481-494
    • Kroetz, D.L.1    Pauli-Magnus, C.2    Hodges, L.M.3
  • 8
    • 25144433260 scopus 로고    scopus 로고
    • Multidrug resistance polypeptide 1 (MDR1, ABCB1) variant 3435C>T affects mRNA stability
    • Wang D, Johnson AD, Papp AC, Kroetz DL, Sadée W. Multidrug resistance polypeptide 1 (MDR1, ABCB1) variant 3435C>T affects mRNA stability. Pharmacogenet Genomics. 2005;15(10):693-704.
    • (2005) Pharmacogenet Genomics. , vol.15 , Issue.10 , pp. 693-704
    • Wang, D.1    Johnson, A.D.2    Papp, A.C.3    Kroetz, D.L.4    Sadée, W.5
  • 9
    • 0343416856 scopus 로고    scopus 로고
    • Contributions of hepatic and intestinal metabolism and P-glycoprotein to cyclosporine and tacrolimus oral drug delivery
    • Hebert MF. Contributions of hepatic and intestinal metabolism and P-glycoprotein to cyclosporine and tacrolimus oral drug delivery. Adv Drug Deliv Rev. 1997;27(2-3):201-214.
    • (1997) Adv Drug Deliv Rev. , vol.27 , Issue.2-3 , pp. 201-214
    • Hebert, M.F.1
  • 10
    • 0035054725 scopus 로고    scopus 로고
    • The gut as a barrier to drug absorption: Combined role of cytochrome P450 3A and P-glycoprotein
    • Zhang Y, Benet LZ. The gut as a barrier to drug absorption: combined role of cytochrome P450 3A and P-glycoprotein. Clin Pharmacokinet. 2001;40(3):159-168.
    • (2001) Clin Pharmacokinet. , vol.40 , Issue.3 , pp. 159-168
    • Zhang, Y.1    Benet, L.Z.2
  • 11
    • 0030006845 scopus 로고    scopus 로고
    • Bimodal distribution of renal cytochrome P450 3A activity in humans
    • Haehner BD, Gorski JC, Vandenbranden M, et al. Bimodal distribution of renal cytochrome P450 3A activity in humans. Mol Pharmacol. 1996;50(1):52-59.
    • (1996) Mol Pharmacol. , vol.50 , Issue.1 , pp. 52-59
    • Haehner, B.D.1    Gorski, J.C.2    Vandenbranden, M.3
  • 12
    • 0037389628 scopus 로고    scopus 로고
    • In vitro and pharmacophore insights into CYP3A enzymes
    • Ekins S, Stresser DM, Williams JA. In vitro and pharmacophore insights into CYP3A enzymes. Trends Pharmacol Sci. 2003;24(4):161-166.
    • (2003) Trends Pharmacol Sci. , vol.24 , Issue.4 , pp. 161-166
    • Ekins, S.1    Stresser, D.M.2    Williams, J.A.3
  • 13
    • 0035071598 scopus 로고    scopus 로고
    • Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression
    • Kuehl P, Zhang J, Lin Y, et al. Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression. Nat Genet. 2001;27(4):383-391.
    • (2001) Nat Genet. , vol.27 , Issue.4 , pp. 383-391
    • Kuehl, P.1    Zhang, J.2    Lin, Y.3
  • 15
    • 34147109227 scopus 로고    scopus 로고
    • Influence of the CYP3A5 genotype on tacrolimus pharmacokinetics and pharmacodynamics in young kidney transplant recipients
    • Ferraresso M, Tirelli A, Ghio L, et al. Influence of the CYP3A5 genotype on tacrolimus pharmacokinetics and pharmacodynamics in young kidney transplant recipients. Pediatr Transplant. 2007;11(3):296-300.
    • (2007) Pediatr Transplant. , vol.11 , Issue.3 , pp. 296-300
    • Ferraresso, M.1    Tirelli, A.2    Ghio, L.3
  • 16
    • 31344466713 scopus 로고    scopus 로고
    • Effect of intestinal CYP3A5 on postoperative tacrolimus trough levels in living-donor liver transplant recipients
    • Uesugi M, Masuda S, Katsura T, Oike F, Takada Y, Inui K. Effect of intestinal CYP3A5 on postoperative tacrolimus trough levels in living-donor liver transplant recipients. Pharmacogenet Genomics. 2006;16(2):119-127.
    • (2006) Pharmacogenet Genomics. , vol.16 , Issue.2 , pp. 119-127
    • Uesugi, M.1    Masuda, S.2    Katsura, T.3    Oike, F.4    Takada, Y.5    Inui, K.6
  • 17
    • 33747080802 scopus 로고    scopus 로고
    • Liver biopsy interpretation for causes of late liver allograft dysfunction
    • Banff Working Group
    • Banff Working Group, Demetris AJ, Adeyi O, et al. Liver biopsy interpretation for causes of late liver allograft dysfunction. Hepatology. 2006;44(2):489-501.
    • (2006) Hepatology. , vol.44 , Issue.2 , pp. 489-501
    • Demetris, A.J.1    Adeyi, O.2
  • 18
    • 0027418815 scopus 로고
    • Human Pglycoprotein transports cyclosporin A and FK506
    • Saeki T, Ueda K, Tanigawara Y, Hori R, Komano T. Human Pglycoprotein transports cyclosporin A and FK506. J Biol Chem. 1993;268(9):6077-6080.
    • (1993) J Biol Chem. , vol.268 , Issue.9 , pp. 6077-6080
    • Saeki, T.1    Ueda, K.2    Tanigawara, Y.3    Hori, R.4    Komano, T.5
  • 19
    • 0036851317 scopus 로고    scopus 로고
    • Lowered blood concentration of tacrolimus and its recovery with changes in expression of CYP3A and P-glycoprotein after high-dose steroid therapy
    • Shimada T, Terada A, Yokogawa K, Kaneko H, et al. Lowered blood concentration of tacrolimus and its recovery with changes in expression of CYP3A and P-glycoprotein after high-dose steroid therapy. Transplantation. 2002;74(10):1419-1424.
    • (2002) Transplantation. , vol.74 , Issue.10 , pp. 1419-1424
    • Shimada, T.1    Terada, A.2    Yokogawa, K.3    Kaneko, H.4
  • 20
    • 0037131879 scopus 로고    scopus 로고
    • Genetic contribution to variable human CYP3A-mediated metabolism
    • Lamba JK, Lin YS, Schuetz EG, Thummel KE. Genetic contribution to variable human CYP3A-mediated metabolism. Adv Drug Deliv Rev. 2002;54(10):1271-1294.
    • (2002) Adv Drug Deliv Rev. , vol.54 , Issue.10 , pp. 1271-1294
    • Lamba, J.K.1    Lin, Y.S.2    Schuetz, E.G.3    Thummel, K.E.4
  • 21
    • 84855244864 scopus 로고    scopus 로고
    • Study the polymorphism of CYP3A5 and CYP3A4 loci in Iranian population with laryngeal squamous cell carcinoma
    • Azarpira N, Ashraf MJ, Khademi B, Darai M, Hakimzadeh A, Abedi E. Study the polymorphism of CYP3A5 and CYP3A4 loci in Iranian population with laryngeal squamous cell carcinoma. Mol Biol Rep. 2011;38(8):5443-5448.
    • (2011) Mol Biol Rep. , vol.38 , Issue.8 , pp. 5443-5448
    • Azarpira, N.1    Ashraf, M.J.2    Khademi, B.3    Darai, M.4    Hakimzadeh, A.5    Abedi, E.6
  • 22
    • 84855225042 scopus 로고    scopus 로고
    • The investigation of allele and genotype frequencies of CYP3A5 (1/3) and P2Y12 (T744C) in Iran
    • Azarpira N, Namazi S, Khalili A, Tabesh M. The investigation of allele and genotype frequencies of CYP3A5 (1/3) and P2Y12 (T744C) in Iran. Mol Biol Rep. 2011;38(8):4873-4877.
    • (2011) Mol Biol Rep. , vol.38 , Issue.8 , pp. 4873-4877
    • Azarpira, N.1    Namazi, S.2    Khalili, A.3    Tabesh, M.4
  • 23
    • 45449099489 scopus 로고    scopus 로고
    • Significant impact of gene polymorphisms on tacrolimus but not cyclosporine dosing in Asian renal transplant recipients
    • Loh PT, Lou HX, Zhao Y, Chin YM, Vathsala A. Significant impact of gene polymorphisms on tacrolimus but not cyclosporine dosing in Asian renal transplant recipients. Transplant Proc. 2008;40(5):1690-1695.
    • (2008) Transplant Proc. , vol.40 , Issue.5 , pp. 1690-1695
    • Loh, P.T.1    Lou, H.X.2    Zhao, Y.3    Chin, Y.M.4    Vathsala, A.5
  • 24
    • 67349144040 scopus 로고    scopus 로고
    • CYP3A53A allele associated with tacrolimus trough concentrations but not subclinical acute rejection or chronic allograft nephropathy in Japanese renal transplant recipients
    • Satoh S, Saito M, Inoue T, et al. CYP3A53A allele associated with tacrolimus trough concentrations but not subclinical acute rejection or chronic allograft nephropathy in Japanese renal transplant recipients. Eur J Clin Pharmacol. 2009;65(5):473-481.
    • (2009) Eur J Clin Pharmacol. , vol.65 , Issue.5 , pp. 473-481
    • Satoh, S.1    Saito, M.2    Inoue, T.3
  • 25
    • 33645864935 scopus 로고    scopus 로고
    • Effect of CYP3A5 polymorphism on tacrolimus metabolic clearance in vitro
    • Dai Y, Hebert MF, Isoherranen N, et al. Effect of CYP3A5 polymorphism on tacrolimus metabolic clearance in vitro. Drug Metab Dispos. 2006;34(5):836-847.
    • (2006) Drug Metab Dispos. , vol.34 , Issue.5 , pp. 836-847
    • Dai, Y.1    Hebert, M.F.2    Isoherranen, N.3
  • 26
    • 16244419058 scopus 로고    scopus 로고
    • Genetic polymorphisms of CYP3A5 genes and concentration of the cyclosporine and tacrolimus
    • Zhao Y, Song M, Guan D, et al. Genetic polymorphisms of CYP3A5 genes and concentration of the cyclosporine and tacrolimus. Transplant Proc. 2005;37(1):178-181.
    • (2005) Transplant Proc. , vol.37 , Issue.1 , pp. 178-181
    • Zhao, Y.1    Song, M.2    Guan, D.3
  • 27
    • 54049115013 scopus 로고    scopus 로고
    • CYP3A5*3A allele is associated with reduced lowering-lipid response to atorvastatin in individuals with hypercholesterolemia
    • Willrich MA, Hirata MH, Genvigir FD, et al. CYP3A5*3A allele is associated with reduced lowering-lipid response to atorvastatin in individuals with hypercholesterolemia. Clin Chim Acta. 2008;398(1-2):15-20.
    • (2008) Clin Chim Acta. , vol.398 , Issue.1-2 , pp. 15-20
    • Willrich, M.A.1    Hirata, M.H.2    Genvigir, F.D.3
  • 28
    • 34447549311 scopus 로고    scopus 로고
    • Tacrolimus pharmacokinetics and pharmacogenetics: Influence of adenosine triphosphate-binding cassette B1 (ABCB1) and cytochrome (CYP) 3A polymorphisms
    • Op den Buijsch RA, Christiaans MH, Stolk LM, et al. Tacrolimus pharmacokinetics and pharmacogenetics: influence of adenosine triphosphate-binding cassette B1 (ABCB1) and cytochrome (CYP) 3A polymorphisms. Fundam Clin Pharmacol. 2007;21(4):427-435.
    • (2007) Fundam Clin Pharmacol. , vol.21 , Issue.4 , pp. 427-435
    • Op den Buijsch, R.A.1    Christiaans, M.H.2    Stolk, L.M.3
  • 29
    • 0036667953 scopus 로고    scopus 로고
    • C3435T polymorphism in the MDR1 gene affects the enterocyte expression level of CYP3A4 rather than Pgp in recipients of living-donor liver transplantation
    • Goto M, Masuda S, Saito H, et al. C3435T polymorphism in the MDR1 gene affects the enterocyte expression level of CYP3A4 rather than Pgp in recipients of living-donor liver transplantation. Pharmacogenetics. 2002;12(6):451-457.
    • (2002) Pharmacogenetics. , vol.12 , Issue.6 , pp. 451-457
    • Goto, M.1    Masuda, S.2    Saito, H.3
  • 30
    • 0038304548 scopus 로고    scopus 로고
    • Association of the multidrug resistance-1 gene single-nucleotide polymorphisms with the tacrolimus dose requirements in renal transplant recipients
    • Anglicheau D, Verstuyft C, Laurent-Puig P, et al. Association of the multidrug resistance-1 gene single-nucleotide polymorphisms with the tacrolimus dose requirements in renal transplant recipients. J Am Soc Nephrol. 2003;14(7):1889-1896.
    • (2003) J Am Soc Nephrol. , vol.14 , Issue.7 , pp. 1889-1896
    • Anglicheau, D.1    Verstuyft, C.2    Laurent-Puig, P.3
  • 31
    • 27644467774 scopus 로고    scopus 로고
    • Sirolimus and tacrolimus trough concentrations and dose requirements after kidney transplantation in relation to CYP3A5 and MDR1 polymorphisms and steroids
    • Mourad M, Mourad G, Wallemacq P, et al. Sirolimus and tacrolimus trough concentrations and dose requirements after kidney transplantation in relation to CYP3A5 and MDR1 polymorphisms and steroids. Transplantation. 2005;80(7):977-984.
    • (2005) Transplantation. , vol.80 , Issue.7 , pp. 977-984
    • Mourad, M.1    Mourad, G.2    Wallemacq, P.3
  • 32
    • 34548640104 scopus 로고    scopus 로고
    • Population pharmacokinetics of tacrolimus and CYP3A5, MDR1 and IL-10 polymorphisms in adult liver transplant patients
    • Li D, Lu W, Zhu JY, Gao J, Lou YQ, Zhang GL. Population pharmacokinetics of tacrolimus and CYP3A5, MDR1 and IL-10 polymorphisms in adult liver transplant patients. J Clin Pharm Ther. 2007;32(5):505-515.
    • (2007) J Clin Pharm Ther. , vol.32 , Issue.5 , pp. 505-515
    • Li, D.1    Lu, W.2    Zhu, J.Y.3    Gao, J.4    Lou, Y.Q.5    Zhang, G.L.6
  • 33
    • 67549139183 scopus 로고    scopus 로고
    • The effect of CYP3A5 and ABCB1 single nucleotide polymorphisms on tacrolimus dose requirements in Caucasian liver transplant patients
    • Provenzani A, Notarbartolo M, Labbozzetta M, et al. The effect of CYP3A5 and ABCB1 single nucleotide polymorphisms on tacrolimus dose requirements in Caucasian liver transplant patients. Ann Transplant. 2009;14(1):23-31.
    • (2009) Ann Transplant. , vol.14 , Issue.1 , pp. 23-31
    • Provenzani, A.1    Notarbartolo, M.2    Labbozzetta, M.3
  • 34
    • 65549149071 scopus 로고    scopus 로고
    • Tacrolimus concentrations in relation to CYP3A and ABCB1 polymorphisms among solid organ transplant recipients in Korea
    • Jun KR, Lee W, Jang MS, et al. Tacrolimus concentrations in relation to CYP3A and ABCB1 polymorphisms among solid organ transplant recipients in Korea. Transplantation. 2009;87(8):1225-1231.
    • (2009) Transplantation. , vol.87 , Issue.8 , pp. 1225-1231
    • Jun, K.R.1    Lee, W.2    Jang, M.S.3
  • 35
    • 33745626752 scopus 로고    scopus 로고
    • Association between cyclosporine concentration and genetic polymorphisms of CYP3A5 and MDR1 during the early stage after renal transplantation
    • Azarpira N, Aghdaie MH, Behzad-Behbahanie A, et al. Association between cyclosporine concentration and genetic polymorphisms of CYP3A5 and MDR1 during the early stage after renal transplantation. Exp Clin Transplant. 2006;4(1):416-419.
    • (2006) Exp Clin Transplant. , vol.4 , Issue.1 , pp. 416-419
    • Azarpira, N.1    Aghdaie, M.H.2    Behzad-Behbahanie, A.3
  • 36
    • 78149294395 scopus 로고    scopus 로고
    • Using genetic and clinical factors to predict tacrolimus dose in renal transplant recipients
    • Wang P, Mao Y, Razo J, et al. Using genetic and clinical factors to predict tacrolimus dose in renal transplant recipients. Pharmacogenomics. 2010;11(10):1389-1402.
    • (2010) Pharmacogenomics. , vol.11 , Issue.10 , pp. 1389-1402
    • Wang, P.1    Mao, Y.2    Razo, J.3
  • 37
    • 55749084522 scopus 로고    scopus 로고
    • Clinical relevance and prevalence of polymorphisms in CYP3A5 and MDR1 genes that encode tacrolimus biotransformation enzymes in liver transplant recipients
    • Barrera-Pulido L, Aguilera-García I, Docobo-Pérez F, et al. Clinical relevance and prevalence of polymorphisms in CYP3A5 and MDR1 genes that encode tacrolimus biotransformation enzymes in liver transplant recipients. Transplant Proc. 2008;40(9):2949-2951.
    • (2008) Transplant Proc. , vol.40 , Issue.9 , pp. 2949-2951
    • Barrera-Pulido, L.1    Aguilera-García, I.2    Docobo-Pérez, F.3
  • 38
    • 33646439263 scopus 로고    scopus 로고
    • Tacrolimus dose requirement in relation to donor and recipient ABCB1 and CYP3A5 gene polymorphisms in Chinese liver transplant patients
    • Wei-lin W, Jing J, Shu-sen Z, et al. Tacrolimus dose requirement in relation to donor and recipient ABCB1 and CYP3A5 gene polymorphisms in Chinese liver transplant patients. Liver Transpl. 2006;12(5):775-780.
    • (2006) Liver Transpl. , vol.12 , Issue.5 , pp. 775-780
    • Wei-lin, W.1    Jing, J.2    Shu-sen, Z.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.