Metalloproteinase-mediated shedding of integrin β2 promotes macrophage efflux from inflammatory sites

Journal of Biological Chemistry

Volumn 287, Issue 7, 2012, Pages 4581-4589

  Gomez, Ivan G ^a   Tang, Jingjing ^a   Wilson, Carole L ^a   Yan, Wei ^a,c   Heinecke, Jay W ^b   Harlan, John M ^a,b   Raines, Elaine W ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^c INSTITUTE FOR SYSTEMS BIOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTIVE IMMUNE RESPONSE; CELL SURFACES; HETERODIMERIC COMPLEXES; HETERODIMERS; INNATE IMMUNE RESPONSE; INTEGRINS; INTRACELLULAR ADHESION MOLECULE-1; LYMPH NODE; METALLOPROTEASE INHIBITORS; METALLOPROTEINASES; PERITONEAL MACROPHAGE; TISSUE MACROPHAGES;

ADHESION; CELL MEMBRANES; ENZYME ACTIVITY; MAMMALS; TISSUE;

MACROPHAGES;

ADAM PROTEIN; ADAM10 ENDOPEPTIDASE; ADAM17 PROTEIN; BETA2 INTEGRIN; CD11B ANTIGEN; CD18 ANTIGEN; COLLAGEN; FIBRIN; GELATINASE B; GLYCOPROTEIN P 15095; HETERODIMER; ILOMASTAT; INTERCELLULAR ADHESION MOLECULE 1; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1; METALLOPROTEINASE; THIOGLYCOLIC ACID; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL SURFACE; COMPLEX FORMATION; CONTROLLED STUDY; HUMAN; HUMAN CELL; IN VIVO STUDY; INFLAMMATION; MACROPHAGE MIGRATION; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; PERITONITIS; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEIN PROTEIN INTERACTION; PROTEOLYTIC SHEDDING;

ALPHA-MACROGLOBULINS; ANIMALS; ANTIGENS, CD18; CELL MOVEMENT; CELLS, CULTURED; COLLAGEN; FIBRIN; HUMANS; INFLAMMATION; INTERCELLULAR ADHESION MOLECULE-1; MACROPHAGES, PERITONEAL; METALLOPROTEASES; MICE; MICE, MUTANT STRAINS; PERITONITIS; PROTEIN MULTIMERIZATION;

MUS;

EID: 84856910083     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.321182     Document Type: Article

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