Polyphenols of Mangifera indica modulate arsenite-induced cytotoxicity in a human proximal tubule cell line

Revista Brasileira de Farmacognosia

Volumn 22, Issue 2, 2012, Pages 325-334

  Garrido, Gabino ^a   Romiti, Nadia ^b   Tramonti, Gianfranco ^b   de la Fuente, Francisco ^a   Chieli, Elisabetta ^b  

^a UNIVERSIDAD CATÓLICA DEL NORTE   (Chile)

^b UNIVERSITY OF PISA   (Italy)

Author keywords

Arsenic; HK 2 cells; Mangifera indica; Mangiferin; P glycoprotein; Polyphenols

Indexed keywords

ALBUMIN; ARSENIC TRIOXIDE; CATECHIN; GALLIC ACID; GLYCOPROTEIN P; IRON; MANGIFERA INDICA EXTRACT; MANGIFERA INDICA STEM BARK EXTRACT; MANGIFERIN; POLYPHENOL; QUERCETIN; UNCLASSIFIED DRUG;

ARTICLE; BARK; CELL CULTURE; CELL PROTECTION; CELL SURVIVAL; CELL VIABILITY; CLONOGENIC ASSAY; CONTROLLED STUDY; CYTOTOXICITY; HUMAN; HUMAN CELL; KIDNEY PROXIMAL TUBULE; MANGO; MEDICINAL PLANT; PLANT STEM; PROTEIN EXPRESSION;

EID: 84856890496     PISSN: 0102695X     EISSN: None     Source Type: Journal    
DOI: 10.1590/S0102-695X2011005000212     Document Type: Article

References (48)

1. Anglicheau D, Pallet N, Rabant M, Marquet P, Cassinat B, Méria P, Beaune P, Legendre C, Thervet E 2006. Role of P-glycoprotein in cyclosporine cytotoxicity in the cyclosporine-sirolimus interaction. Kidney Int 70: 1019-1025.
2. Aposhian HV, Aposhian MM 2006. Arsenic toxicology: Five questions. Chem Res Toxicol 19: 1-15.
3. Bera AK, Rana T, Das S, Bandyopadhyay S, Bhattacharya D, Pan D, De S, Das SK 2010. L-Ascorbate protects rat hepatocytes against sodium arsenite-induced cytotoxicity and oxidative damage. Hum Exp Toxicol 29: 103-111.
4. Brammer H, Ravenscroft P 2009. Arsenic in groundwater: A threat to sustainable agriculture in South and South-east Asia. Environ Int 35: 647-654.
5. Catanzaro I, Schiera G, Sciandrello G, Barbata G, Caradonna F, Proia P, Di Liegro I 2010. Biological effects of inorganic arsenic on primary cultures of rat astrocytes. Int J Mol Med 26: 457-462.
6. Caussy D, Priest ND 2008. Introduction to arsenic contamination and health risk assessment with special reference to Bangladesh. Rev Environ Contam T 197: 1-15.
7. Chieli E, Romiti N, Rodeiro I, Garrido G 2009. In vitro effects of Mangifera indica and polyphenols derived on ABCB1/P-glycoprotein activity. Food Chem Toxicol 47: 2703-2710.
8. Chieli E, Romiti N, Rodeiro I, Garrido G 2010. In vitro modulation of ABCB1/P-glycoprotein expression by polyphenols from Mangifera indica. Chem Biol Interact 186: 287-294.
9. Chin K V, Tanaka S, Darlington G, Pastan I, Gottesman MM 1990. Heat shock and arsenite increase expression of the multidrug resistance (MDR1) gene in human renal carcinoma cells. J Biol Chem 265: 221-226.
10. Drobná Z, Walton FS, Paul DS, Xing W, Thomas DJ, Stýblo M 2010. Metabolism of arsenic in human liver: the role of membrane transporters. Arch Toxicol 84: 3-16.
11. Ferreccio C, Sancha AM 2006. Arsenic exposure and its impact on health in Chile. J Health Popul Nutr 24: 164-175.
12. Franken NA, Rodermond HM, Stap J, Haveman J, van Bree C 2006. Clonogenic assay of cells in vitro. Nat Protoc 1: 2315-2319.
13. Gailer J 2009. Chronic toxicity of As(III) in mammals: the role of (GS)(2)AsSe(-). Biochimie 91: 1268-1272.
14. Garrido G, González D, Lemus Y, Delporte C, Núñez-Sellés AJ, Delgado R 2006. Protective effects of a standard extract of Mangifera indica L. (VIMANG) against mouse ear edemas and its inhibition on eicosanoids production in J774 murine macrophages. Phytomedicine 13: 412-418.
15. Garrido G, González D, Romay C, Núñez-Sellés AJ, Delgado R 2008. Scavenger effect of a mango (Mangifera indica L.) food supplement's active ingredient on free radicals produced by human polymorphonuclear cells and hypoxanthine-xanthine oxidase chemiluminescence systems. Food Chem 107: 1008-1014.
16. Garrido G, González D, Lemus Y, García D, Lodeiro L, Quintero G, Delporte C, Núñez-Sellés AJ, Delgado R 2004. In vivo and in vitro anti-inflammatory activity of Mangifera indica L. extract (VIMANG®). Pharmacol Res 50: 143-149.
17. Garrido G, Martínez-Sánchez G, Pardo-Andreu G, García-Rivera D, Hernández-Casaña P, Rodeiro-Guerra I, Guevara-García M, Delgado-Hernández R, Núñez-Sellés, AJ 2007. Recent advances in the research & development of an aqueous stem bark extract obtained from Mangifera indica L. In: Recent Developments in Medicinal Plant Research, (Capasso A., Ed.) p. 69-82.
18. Guha Mazumder DN 2008 Chronic arsenic toxicity & human health. Indian J Med Res 128: 436-447.
19. Gunness P, Aleksa K, Kosuge K, Ito S, Koren G 2010. Comparison of the novel HK-2 human renal proximal tubular cell line with the standard LLC-PK1 cell line in studying drug-induced nephrotoxicity. Can J Physiol Pharm 88: 448-455.
20. Hayakawa T, Kobayashi Y, Cui X, Hirano S 2005. A new metabolic pathway of arsenite: arsenic-glutathione complexes are substrates for human arsenic methyltransferase Cyt19. Arch Toxicol 79: 183-191.
21. Kioka N, Yamano Y, Komano T, Ueda K 1992. Heat-shock responsive elements in the induction of the multidrug resistance gene (MDR1). FEBS Letters 301: 37-40.
22. Kitchin KT, Conolly R 2010. Arsenic-induced carcinogenesisoxidative stress as a possible mode of action and future research needs for more biologically based risk assessment. Chem Res Toxicol 23: 327-335.
23. Jones FT 2007. A broad view of arsenic. Poult Sci S 86: 2-14.
24. Lantz RC, Hays AM 2006. Role of oxidative stress in arsenicinduced toxicity. Drug Metab Rev 38: 791-804.
25. Lindberg AL, Goessler W, Gurzau E, Koppova K, Rudnai P, Kumar R, Fletcher T, Leonardi G, Slotova K, Gheorghiu E, Vahter M 2006. Arsenic exposure in Hungary, Romania and Slovakia. J Environ Monitor 8: 203-208.
26. Liu J, Chen H, Miller DS, Saavedra JE, Keefer LK, Johnson DR, Klaassen CD, Waalkes MP 2001. Overexpression of glutathione S-transferase II and multidrug resistance transport proteins is associated with acquired tolerance to inorganic arsenic. Mol Pharmacol 60: 302-309.
27. Maitra R, Hamilton JW 2005. Arsenite regulates cystic fibrosis transmembrane conductance regulator and P-glycoprotein: Evidence of pathway independence. Cell Physiol Biochem 16: 109-118.
28. Martinez-Sánchez G, Candelario-Jalil E, Giuliani A, León OS, Sam S, Delgado R, Núñez-Sellés AJ 2001. Mangifera indica L. extract (Vimang) reduces ischemia-induced neuronal loss and oxidative damage in the gerbil brain. Free Radical Res 35: 465-473.
29. Martínez-Sánchez G, Delgado R, Nuñez-Sellés AJ, Pérez G, Garrido G, León OS 2000. Evaluation of the in vitro antioxidant activity of Mangifera indica L. extract (Vimang®). Phytother Res 14: 424-427.
30. Masibo M, He Q 2009. Mango bioactive compounds and related nutraceutical properties. Food Rev Int 25: 346-370.
31. Morales AA, Gutman D, Cejas PJ, Lee KP, Boise LH 2009. Reactive oxygen species are not required for an arsenic trioxide-induced antioxidant response or apoptosis. J Biol Chem 284: 12886-12895.
32. Naranmandura H, Ogra Y, Iwata K, Lee J, Suzuki KT, Weinfeld M, Le XC 2009. Evidence for toxicity differences between inorganic arsenite and thioarsenicals in human bladder cancer cells. Toxicol Appl Pharma 238: 133-140.
33. Núñez-Sellés AJ, Vélez Castro HT, Agüero-Agüero J, González-González J, Naddeo F, De Simone F, Rastrelli L 2002. Isolation and quantitative analysis of phenolic antioxidants, free sugars and polyphenols from mango (Mangifera indica L.) stem bark aqueous decoction used in Cuba as a nutritional supplement. J Agr Food Chem 50: 762-766.
34. Núñez-Sellés AJ, Delgado-Hernandez R, Garrido-Garrido G, Garcia-Rivera D, Guevara-Garcia M, Pardo-Andreu GL 2007b. The paradox of natural products as pharmaceuticals. Experimental evidences of a mango stem bark extract. Pharmacol Res 55: 351-358.
35. Núñez AJ, Durruthy MD, Rodríguez E, Nieto L, Nicolais V, Rastrelli L 2007a. Comparison of major and trace element concentration in sixteen varieties of Cuban mango stem bark (Mangifera indica L.). J Agr Food Chem 55: 2176-2181.
36. O'Reilly J, Watts MJ, Shaw R A, Marcilla AL, Ward NI 2010. Arsenic contamination of natural waters in San Juan and La Pampa, Argentina. Environ Geochem Hlth 32: 491-515.
37. Pardo-Andreu GL, Sánchez-Baldoquín C, Avila-González R, Delgado R, Naal Z, Curti, C 2006. Fe(III) improves antioxidant and cytoprotecting activities of mangiferin. Eur J Pharmacol 547: 31-36.
38. Pardo-Andreu GL, Barrios MF, Curti C, Hernández I, Merino N, Lemus Y, Martínez I, Riaño A, Delgado R 2008. Protective effects of Mangifera indica L extract (Vimang), and its major component mangiferin, on iron-induced oxidative damage to rat serum and liver. Pharmacol Res 57: 79-86.
39. Peraza MA, Carter DE, Gandolfi AJ 2003. Toxicity and metabolism of subcytotoxic inorganic arsenic in human renal proximal tubule epithelial cells (HK-2). Cell Biol Toxicol 19: 253-264.
40. Rahman MM, Ng JC, Naidu R, 2009. Chronic exposure of arsenic via drinking water and its adverse health impacts on humans. Environ Geochem Hlth 31: 189-200.
41. Rodeiro I, Donato MT, Jiménez N, Garrido G, Delgado R, Gómez-Lechón MJ 2007. Effects of Mangifera indica L. aqueous extract (Vimang) on primary culture of rat hepatocytes. Food Chem Toxicol 45: 2506-2512.
42. Rodeiro I, Donato MT, Martínez I, Hernández I, Garrido G, González-Lavaut JA, Menéndez R, Laguna A, Castell JV, Gómez-Lechón MJ 2008. Potential hepatoprotective effects of new Cuban natural products in rat hepatocytes cultured. Toxicol in Vitro 22: 1242-1249.
43. Romiti N, Tramonti G, Chieli E, 2002. Influence of different chemicals on MDR-1 P-glycoprotein expression and activity in the HK-2 proximal tubular cell line. Toxicol Appl Pharm 183: 83-91.
44. Singh N, Kumar D, Sahu AP 2007. Arsenic in the environment: effects on human health and possible prevention. J Environ Biol 28: 359-365.
45. Sinha D, Dey S, Bhattacharya RK, Roy M 2007. In vitro mitigation of arsenic toxicity by tea polyphenols in human lymphocytes. J Environ Pathol Tox 26: 207-220.
46. Soria EA, Eynard AR, Bongiovanni GA 2010. Cytoprotective effects of silymarin on epithelial cells against arsenicinduced apoptosis in contrast with quercetin cytotoxicity. Life Sci 87: 309-315.
47. Sun G, Li X, Pi J, Sun Y, Li B, Jin Y, Xu YJ 2006. Current research problems of chronic arsenicosis in China. J Health Popul Nutr 24: 176-181.
48. Tramonti G, Romiti N, Chieli E 2009. Albumin influences expression and function of the membrane transporter P-glycoprotein in HK-2 human proximal tubular cells. J Nephrol 22: 263-272.