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Volumn 28, Issue 1, 2012, Pages 33-49

Management of Cancer in the Older Adult

Author keywords

Biology of cancer; Cancer management; Elderly; Physiologic changes in the elderly, management

Indexed keywords

BEVACIZUMAB; CABAZITAXEL; CAPECITABINE; CARBOPLATIN; CETUXIMAB; CISPLATIN; DOCETAXEL; ERLOTINIB; ETOPOSIDE; EVEROLIMUS; FLUOROURACIL; FOLINIC ACID; GEMCITABINE; INTERFERON; INTERLEUKIN 2; IRINOTECAN; MAMMALIAN TARGET OF RAPAMYCIN INHIBITOR; MITOXANTRONE; OXALIPLATIN; PACLITAXEL; PLACEBO; PLATINUM COMPLEX; SIPULEUCEL T; SUNITINIB; VASCULOTROPIN INHIBITOR;

EID: 84856802493     PISSN: 07490690     EISSN: 18798853     Source Type: Journal    
DOI: 10.1016/j.cger.2011.10.003     Document Type: Review
Times cited : (12)

References (87)
  • 1
    • 0033619959 scopus 로고    scopus 로고
    • Underrepresentation of patients 65 years of age or older in cancer-treatment trials
    • Hutchins L.F., Unger J.M., Crowley J.J., et al. Underrepresentation of patients 65 years of age or older in cancer-treatment trials. N Engl J Med 1999, 341(27):2061-2067.
    • (1999) N Engl J Med , vol.341 , Issue.27 , pp. 2061-2067
    • Hutchins, L.F.1    Unger, J.M.2    Crowley, J.J.3
  • 2
    • 79952319391 scopus 로고    scopus 로고
    • Under-representation of the elderly in cancer clinical trials
    • Lang K.J., Lidder S. Under-representation of the elderly in cancer clinical trials. Br J Hosp Med (Lond) 2010, 71(12):678-681.
    • (2010) Br J Hosp Med (Lond) , vol.71 , Issue.12 , pp. 678-681
    • Lang, K.J.1    Lidder, S.2
  • 3
    • 0028070572 scopus 로고
    • Representation of older patients in cancer treatment trials
    • Trimble E.L., Carter C.L., Cain D., et al. Representation of older patients in cancer treatment trials. Cancer 1994, 74(7 Suppl):2208-2214.
    • (1994) Cancer , vol.74 , Issue.7 SUPPL. , pp. 2208-2214
    • Trimble, E.L.1    Carter, C.L.2    Cain, D.3
  • 4
    • 41949102081 scopus 로고    scopus 로고
    • Choices in cancer treatment: a qualitative study of the older women's (>70 years) perspective
    • Husain L.S., Collins K., Reed M., et al. Choices in cancer treatment: a qualitative study of the older women's (>70 years) perspective. Psychooncology 2008, 17(4):410-416.
    • (2008) Psychooncology , vol.17 , Issue.4 , pp. 410-416
    • Husain, L.S.1    Collins, K.2    Reed, M.3
  • 5
    • 0032923252 scopus 로고    scopus 로고
    • On the role of aging in carcinogenesis
    • Dix D., Cohen P. On the role of aging in carcinogenesis. Anticancer Res 1999, 19(1B):723-726.
    • (1999) Anticancer Res , vol.19 , Issue.1 B , pp. 723-726
    • Dix, D.1    Cohen, P.2
  • 6
    • 0027472558 scopus 로고
    • Influences of chronic tobacco smoke inhalation on aging and oxidant-antioxidant balance in the senescence-accelerated mouse (SAM)-P/2
    • Teramoto S., Fukuchi Y., Uejima Y., et al. Influences of chronic tobacco smoke inhalation on aging and oxidant-antioxidant balance in the senescence-accelerated mouse (SAM)-P/2. Exp Gerontol 1993, 28(1):87-95.
    • (1993) Exp Gerontol , vol.28 , Issue.1 , pp. 87-95
    • Teramoto, S.1    Fukuchi, Y.2    Uejima, Y.3
  • 7
    • 0037198074 scopus 로고    scopus 로고
    • Human premature aging syndromes and genomic instability
    • Bohr V.A. Human premature aging syndromes and genomic instability. Mech Ageing Dev 2002, 123(8):987-993.
    • (2002) Mech Ageing Dev , vol.123 , Issue.8 , pp. 987-993
    • Bohr, V.A.1
  • 8
    • 0013907774 scopus 로고
    • Werner's syndrome a review of its symptomatology, natural history, pathologic features, genetics and relationship to the natural aging process
    • Epstein C.J., Martin G.M., Schultz A.L., et al. Werner's syndrome a review of its symptomatology, natural history, pathologic features, genetics and relationship to the natural aging process. Medicine (Baltimore) 1966, 45(3):177-221.
    • (1966) Medicine (Baltimore) , vol.45 , Issue.3 , pp. 177-221
    • Epstein, C.J.1    Martin, G.M.2    Schultz, A.L.3
  • 9
    • 0025312728 scopus 로고
    • A genetic model for colorectal tumorigenesis
    • Fearon E.R., Vogelstein B. A genetic model for colorectal tumorigenesis. Cell 1990, 61(5):759-767.
    • (1990) Cell , vol.61 , Issue.5 , pp. 759-767
    • Fearon, E.R.1    Vogelstein, B.2
  • 10
    • 0027285475 scopus 로고
    • Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis
    • Ionov Y., Peinado M.A., Malkhosyan S., et al. Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis. Nature 1993, 363(6429):558-561.
    • (1993) Nature , vol.363 , Issue.6429 , pp. 558-561
    • Ionov, Y.1    Peinado, M.A.2    Malkhosyan, S.3
  • 11
    • 34447517413 scopus 로고    scopus 로고
    • Delayed ageing through damage protection by the Arf/p53 pathway
    • Matheu A., Maraver A., Klatt P., et al. Delayed ageing through damage protection by the Arf/p53 pathway. Nature 2007, 448(7151):375-379.
    • (2007) Nature , vol.448 , Issue.7151 , pp. 375-379
    • Matheu, A.1    Maraver, A.2    Klatt, P.3
  • 12
    • 0027998414 scopus 로고
    • Age-dependent regulation of the tumorigenic potential of neoplastically transformed rat liver epithelial cells by the liver microenvironment
    • McCullough K.D., Coleman W.B., Smith G.J., et al. Age-dependent regulation of the tumorigenic potential of neoplastically transformed rat liver epithelial cells by the liver microenvironment. Cancer Res 1994, 54(14):3668-3671.
    • (1994) Cancer Res , vol.54 , Issue.14 , pp. 3668-3671
    • McCullough, K.D.1    Coleman, W.B.2    Smith, G.J.3
  • 13
    • 0029066689 scopus 로고
    • Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability
    • Markowitz S., Wang J., Myeroff L., et al. Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability. Science 1995, 268(5215):1336-1338.
    • (1995) Science , vol.268 , Issue.5215 , pp. 1336-1338
    • Markowitz, S.1    Wang, J.2    Myeroff, L.3
  • 14
    • 23344445915 scopus 로고    scopus 로고
    • Clinical practice guidelines and quality of care for older patients with multiple comorbid diseases: implications for pay for performance
    • Boyd C.M., Darer J., Boult C., et al. Clinical practice guidelines and quality of care for older patients with multiple comorbid diseases: implications for pay for performance. JAMA 2005, 294(6):716-724.
    • (2005) JAMA , vol.294 , Issue.6 , pp. 716-724
    • Boyd, C.M.1    Darer, J.2    Boult, C.3
  • 15
    • 33744818197 scopus 로고    scopus 로고
    • Comorbidity, disability, and geriatric syndromes in elderly cancer patients receiving home health care
    • Koroukian S.M., Murray P., Madigan E., et al. Comorbidity, disability, and geriatric syndromes in elderly cancer patients receiving home health care. J Clin Oncol 2006, 24(15):2304-2310.
    • (2006) J Clin Oncol , vol.24 , Issue.15 , pp. 2304-2310
    • Koroukian, S.M.1    Murray, P.2    Madigan, E.3
  • 16
    • 0142008446 scopus 로고    scopus 로고
    • Undertreatment strongly decreases prognosis of breast cancer in elderly women
    • Bouchardy C., Rapiti E., Fioretta G., et al. Undertreatment strongly decreases prognosis of breast cancer in elderly women. J Clin Oncol Oct 1 2003, 21(19):3580-3587.
    • (2003) J Clin Oncol , vol.21 , Issue.19 , pp. 3580-3587
    • Bouchardy, C.1    Rapiti, E.2    Fioretta, G.3
  • 17
    • 3242816208 scopus 로고    scopus 로고
    • Cardiac toxicity of alemtuzumab in patients with mycosis fungoides/Sezary syndrome
    • Lenihan D.J., Alencar A.J., Yang D., et al. Cardiac toxicity of alemtuzumab in patients with mycosis fungoides/Sezary syndrome. Blood 2004, 104(3):655-658.
    • (2004) Blood , vol.104 , Issue.3 , pp. 655-658
    • Lenihan, D.J.1    Alencar, A.J.2    Yang, D.3
  • 18
    • 0033920730 scopus 로고    scopus 로고
    • Management of cancer in the older person: a practical approach
    • Balducci L., Extermann M. Management of cancer in the older person: a practical approach. Oncologist 2000, 5(3):224-237.
    • (2000) Oncologist , vol.5 , Issue.3 , pp. 224-237
    • Balducci, L.1    Extermann, M.2
  • 19
    • 2642572647 scopus 로고    scopus 로고
    • Aging biology and geriatric clinical pharmacology
    • McLean A.J., Le Couteur D.G. Aging biology and geriatric clinical pharmacology. Pharmacol Rev 2004, 56(2):163-184.
    • (2004) Pharmacol Rev , vol.56 , Issue.2 , pp. 163-184
    • McLean, A.J.1    Le Couteur, D.G.2
  • 20
    • 0031417567 scopus 로고    scopus 로고
    • Pulmonary and cardiac late effects of ionizing radiations alone or combined with chemotherapy
    • [in French]
    • Girinsky T., Cosset J.M. Pulmonary and cardiac late effects of ionizing radiations alone or combined with chemotherapy. Cancer Radiother 1997, 1(6):735-743. [in French].
    • (1997) Cancer Radiother , vol.1 , Issue.6 , pp. 735-743
    • Girinsky, T.1    Cosset, J.M.2
  • 21
    • 0343080998 scopus 로고    scopus 로고
    • A prospective pharmacologic evaluation of age-related toxicity of adjuvant chemotherapy in women with breast cancer
    • Dees E.C., O'Reilly S., Goodman S.N., et al. A prospective pharmacologic evaluation of age-related toxicity of adjuvant chemotherapy in women with breast cancer. Cancer Invest 2000, 18(6):521-529.
    • (2000) Cancer Invest , vol.18 , Issue.6 , pp. 521-529
    • Dees, E.C.1    O'Reilly, S.2    Goodman, S.N.3
  • 22
    • 70349456340 scopus 로고    scopus 로고
    • Multidimensional geriatric evaluation for older cancer patients as a clinical and research tool
    • Brunello A., Sandri R., Extermann M. Multidimensional geriatric evaluation for older cancer patients as a clinical and research tool. Cancer Treat Rev 2009, 35(6):487-492.
    • (2009) Cancer Treat Rev , vol.35 , Issue.6 , pp. 487-492
    • Brunello, A.1    Sandri, R.2    Extermann, M.3
  • 23
    • 0026440034 scopus 로고
    • Value of functional status as a predictor of mortality: results of a prospective study
    • [erratum in Am J Med 199;94(5):560; Am J Med 1993;94(2):232]
    • Reuben D.B., Rubenstein L.V., Hirsch S.H., et al. Value of functional status as a predictor of mortality: results of a prospective study. Am J Med 1992, 93(6):663-669. [erratum in Am J Med 199;94(5):560; Am J Med 1993;94(2):232].
    • (1992) Am J Med , vol.93 , Issue.6 , pp. 663-669
    • Reuben, D.B.1    Rubenstein, L.V.2    Hirsch, S.H.3
  • 24
    • 0034749950 scopus 로고    scopus 로고
    • Weight change in old age and its association with mortality
    • Newman A.B., Yanez D., Harris T., et al. Weight change in old age and its association with mortality. J Am Geriatr Soc 2001, 49(10):1309-1318.
    • (2001) J Am Geriatr Soc , vol.49 , Issue.10 , pp. 1309-1318
    • Newman, A.B.1    Yanez, D.2    Harris, T.3
  • 25
    • 0027330389 scopus 로고
    • Intercommunity variations in the association between social ties and mortality in the elderly. A comparative analysis of three communities
    • Seeman T.E., Berkman L.F., Kohout F., et al. Intercommunity variations in the association between social ties and mortality in the elderly. A comparative analysis of three communities. Ann Epidemiol 1993, 3(4):325-335.
    • (1993) Ann Epidemiol , vol.3 , Issue.4 , pp. 325-335
    • Seeman, T.E.1    Berkman, L.F.2    Kohout, F.3
  • 26
    • 0345743476 scopus 로고    scopus 로고
    • A comprehensive geriatric intervention detects multiple problems in older breast cancer patients
    • Extermann M., Meyer J., McGinnis M., et al. A comprehensive geriatric intervention detects multiple problems in older breast cancer patients. Crit Rev Oncol Hematol 2004, 49(1):69-75.
    • (2004) Crit Rev Oncol Hematol , vol.49 , Issue.1 , pp. 69-75
    • Extermann, M.1    Meyer, J.2    McGinnis, M.3
  • 27
    • 80052704591 scopus 로고    scopus 로고
    • Predicting chemotherapy toxicity in older adults with cancer: a prospective multicenter study
    • Hurria A., Togawa K., Mohile S.G., et al. Predicting chemotherapy toxicity in older adults with cancer: a prospective multicenter study. J Clin Oncol 2011, 29(25):3457-3465.
    • (2011) J Clin Oncol , vol.29 , Issue.25 , pp. 3457-3465
    • Hurria, A.1    Togawa, K.2    Mohile, S.G.3
  • 28
    • 34249774066 scopus 로고    scopus 로고
    • Comprehensive geriatric assessment for older patients with cancer
    • Extermann M., Hurria A. Comprehensive geriatric assessment for older patients with cancer. J Clin Oncol 2007, 25(14):1824-1831.
    • (2007) J Clin Oncol , vol.25 , Issue.14 , pp. 1824-1831
    • Extermann, M.1    Hurria, A.2
  • 29
    • 0035467993 scopus 로고    scopus 로고
    • Global cancer statistics in the year 2000
    • Parkin D.M. Global cancer statistics in the year 2000. Lancet Oncol 2001, 2(9):533-543.
    • (2001) Lancet Oncol , vol.2 , Issue.9 , pp. 533-543
    • Parkin, D.M.1
  • 30
    • 70449102673 scopus 로고    scopus 로고
    • Treatment of advanced non-small-cell lung cancer in the elderly
    • Gridelli C., Maione P., Rossi A., et al. Treatment of advanced non-small-cell lung cancer in the elderly. Lung Cancer 2009, 66(3):282-286.
    • (2009) Lung Cancer , vol.66 , Issue.3 , pp. 282-286
    • Gridelli, C.1    Maione, P.2    Rossi, A.3
  • 31
    • 0344631738 scopus 로고    scopus 로고
    • Ten-year survey of lung cancer treatment and survival in hospitals in the United States: a national cancer data base report
    • Fry W.A., Phillips J.L., Menck H.R. Ten-year survey of lung cancer treatment and survival in hospitals in the United States: a national cancer data base report. Cancer 1999, 86(9):1867-1876.
    • (1999) Cancer , vol.86 , Issue.9 , pp. 1867-1876
    • Fry, W.A.1    Phillips, J.L.2    Menck, H.R.3
  • 32
    • 0037028750 scopus 로고    scopus 로고
    • Cisplatin-based therapy for elderly patients with advanced non-small-cell lung cancer: implications of Eastern Cooperative Oncology Group 5592, a randomized trial
    • Langer C.J., Manola J., Bernardo P., et al. Cisplatin-based therapy for elderly patients with advanced non-small-cell lung cancer: implications of Eastern Cooperative Oncology Group 5592, a randomized trial. J Natl Cancer Inst 2002, 94(3):173-181.
    • (2002) J Natl Cancer Inst , vol.94 , Issue.3 , pp. 173-181
    • Langer, C.J.1    Manola, J.2    Bernardo, P.3
  • 33
    • 0028843552 scopus 로고
    • Chemotherapy in non-small cell lung cancer: a meta-analysis using updated data on individual patients from 52 randomised clinical trials. Non-small Cell Lung Cancer Collaborative Group
    • Anonymous
    • Chemotherapy in non-small cell lung cancer: a meta-analysis using updated data on individual patients from 52 randomised clinical trials. Non-small Cell Lung Cancer Collaborative Group. BMJ 1995, 311(7010):899-909. Anonymous.
    • (1995) BMJ , vol.311 , Issue.7010 , pp. 899-909
  • 34
    • 16644396077 scopus 로고    scopus 로고
    • Single-agent versus combination chemotherapy in advanced non-small-cell lung cancer: the cancer and leukemia group B (study 9730)
    • Lilenbaum R.C., Herndon J.E., List M.A., et al. Single-agent versus combination chemotherapy in advanced non-small-cell lung cancer: the cancer and leukemia group B (study 9730). J Clin Oncol 2005, 23(1):190-196.
    • (2005) J Clin Oncol , vol.23 , Issue.1 , pp. 190-196
    • Lilenbaum, R.C.1    Herndon, J.E.2    List, M.A.3
  • 35
    • 80052964872 scopus 로고    scopus 로고
    • Carboplatin and weekly paclitaxel doublet chemotherapy compared with monotherapy in elderly patients with advanced non-small-cell lung cancer: IFCT-0501 randomised, phase 3 trial
    • Quoix E., Zalcman G.R., Oster J.P., et al. Carboplatin and weekly paclitaxel doublet chemotherapy compared with monotherapy in elderly patients with advanced non-small-cell lung cancer: IFCT-0501 randomised, phase 3 trial. Lancet 2011, 378(9796):1079-1088.
    • (2011) Lancet , vol.378 , Issue.9796 , pp. 1079-1088
    • Quoix, E.1    Zalcman, G.R.2    Oster, J.P.3
  • 36
    • 22044445517 scopus 로고    scopus 로고
    • Erlotinib in previously treated non-small-cell lung cancer
    • Shepherd F.A., Rodrigues Pereira J., Ciuleanu T., et al. Erlotinib in previously treated non-small-cell lung cancer. N Engl J Med 2005, 353(2):123-132.
    • (2005) N Engl J Med , vol.353 , Issue.2 , pp. 123-132
    • Shepherd, F.A.1    Rodrigues Pereira, J.2    Ciuleanu, T.3
  • 37
    • 37649004819 scopus 로고    scopus 로고
    • Lung cancer in elderly patients: an analysis of the surveillance, epidemiology, and end results database
    • Owonikoko T.K., Ragin C.C., Belani C.P., et al. Lung cancer in elderly patients: an analysis of the surveillance, epidemiology, and end results database. J Clin Oncol 2007, 25(35):5570-5577.
    • (2007) J Clin Oncol , vol.25 , Issue.35 , pp. 5570-5577
    • Owonikoko, T.K.1    Ragin, C.C.2    Belani, C.P.3
  • 38
    • 0036135190 scopus 로고    scopus 로고
    • Carboplatin-etoposide combination in small cell lung cancer patients older than 70 years: a phase II trial
    • Larive S., Bombaron P., Riou R., et al. Carboplatin-etoposide combination in small cell lung cancer patients older than 70 years: a phase II trial. Lung Cancer 2002, 35(1):1-7.
    • (2002) Lung Cancer , vol.35 , Issue.1 , pp. 1-7
    • Larive, S.1    Bombaron, P.2    Riou, R.3
  • 40
    • 33846252857 scopus 로고    scopus 로고
    • Chemotherapy for older patients with prostate cancer
    • Anderson J., Van Poppel H., Bellmunt J., et al. Chemotherapy for older patients with prostate cancer. BJU Int 2007, 99(2):269-273.
    • (2007) BJU Int , vol.99 , Issue.2 , pp. 269-273
    • Anderson, J.1    Van Poppel, H.2    Bellmunt, J.3
  • 41
    • 38349167518 scopus 로고    scopus 로고
    • Docetaxel plus prednisone or mitoxantrone plus prednisone for advanced prostate cancer: updated survival in the TAX 327 study
    • Berthold D.R., Pond G.R., Soban F., et al. Docetaxel plus prednisone or mitoxantrone plus prednisone for advanced prostate cancer: updated survival in the TAX 327 study. J Clin Oncol 2008, 26(2):242-245.
    • (2008) J Clin Oncol , vol.26 , Issue.2 , pp. 242-245
    • Berthold, D.R.1    Pond, G.R.2    Soban, F.3
  • 42
    • 0346334660 scopus 로고    scopus 로고
    • Weekly docetaxel in elderly patients with prostate cancer: efficacy and toxicity in patients at least 70 years of age compared with patients younger than 70 years
    • Beer T.M., Berry W., Wersinger E.M., et al. Weekly docetaxel in elderly patients with prostate cancer: efficacy and toxicity in patients at least 70 years of age compared with patients younger than 70 years. Clin Prostate Cancer 2003, 2(3):167-172.
    • (2003) Clin Prostate Cancer , vol.2 , Issue.3 , pp. 167-172
    • Beer, T.M.1    Berry, W.2    Wersinger, E.M.3
  • 43
    • 49449085813 scopus 로고    scopus 로고
    • A randomized phase II trial comparing weekly taxotere plus prednisolone versus prednisolone alone in androgen-independent prostate cancer
    • Fossa S.D. A randomized phase II trial comparing weekly taxotere plus prednisolone versus prednisolone alone in androgen-independent prostate cancer. Front Radiat Ther Oncol 2008, 41:108-116.
    • (2008) Front Radiat Ther Oncol , vol.41 , pp. 108-116
    • Fossa, S.D.1
  • 44
    • 65049085711 scopus 로고    scopus 로고
    • Docetaxel-based chemotherapy in elderly patients (age 75 and older) with castration-resistant prostate cancer
    • Italiano A., Ortholan C., Oudard S., et al. Docetaxel-based chemotherapy in elderly patients (age 75 and older) with castration-resistant prostate cancer. Eur Urol 2009, 55(6):1368-1375.
    • (2009) Eur Urol , vol.55 , Issue.6 , pp. 1368-1375
    • Italiano, A.1    Ortholan, C.2    Oudard, S.3
  • 45
    • 79957443342 scopus 로고    scopus 로고
    • Abiraterone and increased survival in metastatic prostate cancer
    • de Bono J.S., Logothetis C.J., Molina A., et al. Abiraterone and increased survival in metastatic prostate cancer. N Engl J Med 2011, 364(21):1995-2005.
    • (2011) N Engl J Med , vol.364 , Issue.21 , pp. 1995-2005
    • de Bono, J.S.1    Logothetis, C.J.2    Molina, A.3
  • 46
    • 77955066199 scopus 로고    scopus 로고
    • Sipuleucel-T immunotherapy for castration-resistant prostate cancer
    • Kantoff P.W., Higano C.S., Shore N.D., et al. Sipuleucel-T immunotherapy for castration-resistant prostate cancer. N Engl J Med 2010, 363(5):411-422.
    • (2010) N Engl J Med , vol.363 , Issue.5 , pp. 411-422
    • Kantoff, P.W.1    Higano, C.S.2    Shore, N.D.3
  • 47
    • 77957682309 scopus 로고    scopus 로고
    • Prednisone plus cabazitaxel or mitoxantrone for metastatic castration-resistant prostate cancer progressing after docetaxel treatment: a randomised open-label trial
    • de Bono J.S., Oudard S., Ozguroglu M., et al. Prednisone plus cabazitaxel or mitoxantrone for metastatic castration-resistant prostate cancer progressing after docetaxel treatment: a randomised open-label trial. Lancet 2010, 376(9747):1147-1154.
    • (2010) Lancet , vol.376 , Issue.9747 , pp. 1147-1154
    • de Bono, J.S.1    Oudard, S.2    Ozguroglu, M.3
  • 48
    • 37849033723 scopus 로고    scopus 로고
    • Urothelial tumors of the bladder
    • Saunders Elsevier, Philadelphia, M.F. Campbell, A.J. Wein, L.R. Kavoussi (Eds.)
    • Messing E. Urothelial tumors of the bladder. Campbell-Walsh urology 2007, 2407-2446. Saunders Elsevier, Philadelphia. 9th edition. M.F. Campbell, A.J. Wein, L.R. Kavoussi (Eds.).
    • (2007) Campbell-Walsh urology , pp. 2407-2446
    • Messing, E.1
  • 49
  • 50
    • 40849133749 scopus 로고    scopus 로고
    • Late age (85 years or older) peak incidence of bladder cancer
    • Schultzel M., Saltzstein S.L., Downs T.M., et al. Late age (85 years or older) peak incidence of bladder cancer. J Urol 2008, 179(4):1302-1306.
    • (2008) J Urol , vol.179 , Issue.4 , pp. 1302-1306
    • Schultzel, M.1    Saltzstein, S.L.2    Downs, T.M.3
  • 51
    • 0035254218 scopus 로고    scopus 로고
    • Radical cystectomy in the treatment of invasive bladder cancer: long-term results in 1,054 patients
    • Stein J.P., Lieskovsky G., Cote R., et al. Radical cystectomy in the treatment of invasive bladder cancer: long-term results in 1,054 patients. J Clin Oncol 2001, 19(3):666-675.
    • (2001) J Clin Oncol , vol.19 , Issue.3 , pp. 666-675
    • Stein, J.P.1    Lieskovsky, G.2    Cote, R.3
  • 52
    • 26444619729 scopus 로고    scopus 로고
    • Age and comorbidity impact surgical therapy in older bladder carcinoma patients
    • Prout G.R., Wesley M.N., Yancik R., et al. Age and comorbidity impact surgical therapy in older bladder carcinoma patients. Cancer 2005, 104(8):1638-1647.
    • (2005) Cancer , vol.104 , Issue.8 , pp. 1638-1647
    • Prout, G.R.1    Wesley, M.N.2    Yancik, R.3
  • 53
    • 59249097325 scopus 로고    scopus 로고
    • The prognostic significance of advanced age in patients with bladder cancer treated with radical cystectomy
    • Resorlu B., Beduk Y., Baltaci S., et al. The prognostic significance of advanced age in patients with bladder cancer treated with radical cystectomy. BJU Int 2009, 103(4):480-483.
    • (2009) BJU Int , vol.103 , Issue.4 , pp. 480-483
    • Resorlu, B.1    Beduk, Y.2    Baltaci, S.3
  • 54
    • 0036720853 scopus 로고    scopus 로고
    • Phase II study of paclitaxel plus carboplatin in patients with advanced carcinoma of the urothelium and renal dysfunction (E2896)
    • Vaughn D.J., Manola J., Dreicer R., et al. Phase II study of paclitaxel plus carboplatin in patients with advanced carcinoma of the urothelium and renal dysfunction (E2896). Cancer 2002, 95(5):1022-1027.
    • (2002) Cancer , vol.95 , Issue.5 , pp. 1022-1027
    • Vaughn, D.J.1    Manola, J.2    Dreicer, R.3
  • 55
    • 4444369379 scopus 로고    scopus 로고
    • Gemcitabine and carboplatin combination as first-line treatment in elderly patients and those unfit for cisplatin-based chemotherapy with advanced bladder carcinoma: Phase II study of the Hellenic Co-operative Oncology Group
    • Linardou H., Aravantinos G., Efstathiou E., et al. Gemcitabine and carboplatin combination as first-line treatment in elderly patients and those unfit for cisplatin-based chemotherapy with advanced bladder carcinoma: Phase II study of the Hellenic Co-operative Oncology Group. Urology 2004, 64(3):479-484.
    • (2004) Urology , vol.64 , Issue.3 , pp. 479-484
    • Linardou, H.1    Aravantinos, G.2    Efstathiou, E.3
  • 56
    • 44149097205 scopus 로고    scopus 로고
    • Editorial comment on: impact of gender in renal cell carcinoma: an analysis of the SEER database
    • Murai M. Editorial comment on: impact of gender in renal cell carcinoma: an analysis of the SEER database. Eur Urol 2008, 54(1):140-141.
    • (2008) Eur Urol , vol.54 , Issue.1 , pp. 140-141
    • Murai, M.1
  • 57
    • 0034796962 scopus 로고    scopus 로고
    • The changing natural history of renal cell carcinoma
    • Pantuck A.J., Zisman A., Belldegrun A.S. The changing natural history of renal cell carcinoma. J Urol 2001, 166(5):1611-1623.
    • (2001) J Urol , vol.166 , Issue.5 , pp. 1611-1623
    • Pantuck, A.J.1    Zisman, A.2    Belldegrun, A.S.3
  • 58
    • 33751032350 scopus 로고    scopus 로고
    • The evolving presentation of renal carcinoma in the United States: trends from the Surveillance, Epidemiology, and End Results program
    • [discussion: 2400]
    • Nguyen M.M., Gill I.S., Ellison L.M., et al. The evolving presentation of renal carcinoma in the United States: trends from the Surveillance, Epidemiology, and End Results program. J Urol 2006, 176(6 Pt 1):2397-2400. [discussion: 2400].
    • (2006) J Urol , vol.176 , Issue.6 PART 1 , pp. 2397-2400
    • Nguyen, M.M.1    Gill, I.S.2    Ellison, L.M.3
  • 59
    • 33846815531 scopus 로고    scopus 로고
    • Cytoreductive nephrectomy in the elderly patient: the M. D. Anderson Cancer Center experience
    • Kader A.K., Tamboli P., Luongo T., et al. Cytoreductive nephrectomy in the elderly patient: the M. D. Anderson Cancer Center experience. J Urol 2007, 177(3):855-861.
    • (2007) J Urol , vol.177 , Issue.3 , pp. 855-861
    • Kader, A.K.1    Tamboli, P.2    Luongo, T.3
  • 60
    • 79951935241 scopus 로고    scopus 로고
    • Another step toward the cure of metastatic renal cell carcinoma?
    • Vogelzang N.J. Another step toward the cure of metastatic renal cell carcinoma?. J Clin Oncol 2010, 28(34):5017-5019.
    • (2010) J Clin Oncol , vol.28 , Issue.34 , pp. 5017-5019
    • Vogelzang, N.J.1
  • 61
    • 33846148701 scopus 로고    scopus 로고
    • Sorafenib in advanced clear-cell renal-cell carcinoma
    • Escudier B., Eisen T., Stadler W.M., et al. Sorafenib in advanced clear-cell renal-cell carcinoma. N Engl J Med 2007, 356(2):125-134.
    • (2007) N Engl J Med , vol.356 , Issue.2 , pp. 125-134
    • Escudier, B.1    Eisen, T.2    Stadler, W.M.3
  • 62
    • 33846181370 scopus 로고    scopus 로고
    • Sunitinib versus interferon alfa in metastatic renal-cell carcinoma
    • Motzer R.J., Hutson T.E., Tomczak P., et al. Sunitinib versus interferon alfa in metastatic renal-cell carcinoma. N Engl J Med 2007, 356(2):115-124.
    • (2007) N Engl J Med , vol.356 , Issue.2 , pp. 115-124
    • Motzer, R.J.1    Hutson, T.E.2    Tomczak, P.3
  • 63
    • 34249779568 scopus 로고    scopus 로고
    • Temsirolimus, interferon alfa, or both for advanced renal-cell carcinoma
    • Hudes G., Carducci M., Tomczak P., et al. Temsirolimus, interferon alfa, or both for advanced renal-cell carcinoma. N Engl J Med 2007, 356(22):2271-2281.
    • (2007) N Engl J Med , vol.356 , Issue.22 , pp. 2271-2281
    • Hudes, G.1    Carducci, M.2    Tomczak, P.3
  • 64
    • 33748526494 scopus 로고    scopus 로고
    • Clinical response to therapy targeted at vascular endothelial growth factor in metastatic renal cell carcinoma: impact of patient characteristics and Von Hippel-Lindau gene status
    • Rini B.I., Jaeger E., Weinberg V., et al. Clinical response to therapy targeted at vascular endothelial growth factor in metastatic renal cell carcinoma: impact of patient characteristics and Von Hippel-Lindau gene status. BJU Int 2006, 98(4):756-762.
    • (2006) BJU Int , vol.98 , Issue.4 , pp. 756-762
    • Rini, B.I.1    Jaeger, E.2    Weinberg, V.3
  • 65
    • 43549126000 scopus 로고    scopus 로고
    • Chemotherapy in elderly patients with colorectal cancer
    • Kohne C.H., Folprecht G., Goldberg R.M., et al. Chemotherapy in elderly patients with colorectal cancer. Oncologist 2008, 13(4):390-402.
    • (2008) Oncologist , vol.13 , Issue.4 , pp. 390-402
    • Kohne, C.H.1    Folprecht, G.2    Goldberg, R.M.3
  • 66
    • 0033504042 scopus 로고    scopus 로고
    • Clinical score for predicting recurrence after hepatic resection for metastatic colorectal cancer: analysis of 1001 consecutive cases
    • [discussion: 318-31]
    • Fong Y., Fortner J., Sun R.L., et al. Clinical score for predicting recurrence after hepatic resection for metastatic colorectal cancer: analysis of 1001 consecutive cases. Ann Surg 1999, 230(3):309-318. [discussion: 318-31].
    • (1999) Ann Surg , vol.230 , Issue.3 , pp. 309-318
    • Fong, Y.1    Fortner, J.2    Sun, R.L.3
  • 67
    • 34848818021 scopus 로고    scopus 로고
    • Surgical treatment of liver metastases from colorectal carcinoma in elderly patients. When is it worthwhile?
    • Figueras J., Ramos E., Lopez-Ben S., et al. Surgical treatment of liver metastases from colorectal carcinoma in elderly patients. When is it worthwhile?. Clin Transl Oncol 2007, 9(6):392-400.
    • (2007) Clin Transl Oncol , vol.9 , Issue.6 , pp. 392-400
    • Figueras, J.1    Ramos, E.2    Lopez-Ben, S.3
  • 68
    • 76649122170 scopus 로고    scopus 로고
    • Liver resection of colorectal metastases in elderly patients
    • Adam R., Frilling A., Elias D., et al. Liver resection of colorectal metastases in elderly patients. Br J Surg 2010, 97(3):366-376.
    • (2010) Br J Surg , vol.97 , Issue.3 , pp. 366-376
    • Adam, R.1    Frilling, A.2    Elias, D.3
  • 69
    • 4644288273 scopus 로고    scopus 로고
    • Efficacy of 5-fluorouracil-based chemotherapy in elderly patients with metastatic colorectal cancer: a pooled analysis of clinical trials
    • Folprecht G., Cunningham D., Ross P., et al. Efficacy of 5-fluorouracil-based chemotherapy in elderly patients with metastatic colorectal cancer: a pooled analysis of clinical trials. Ann Oncol 2004, 15(9):1330-1338.
    • (2004) Ann Oncol , vol.15 , Issue.9 , pp. 1330-1338
    • Folprecht, G.1    Cunningham, D.2    Ross, P.3
  • 70
    • 34447277453 scopus 로고    scopus 로고
    • Sequential versus combination chemotherapy with capecitabine, irinotecan, and oxaliplatin in advanced colorectal cancer (CAIRO): a phase III randomised controlled trial
    • Koopman M., Antonini N.F., Douma J., et al. Sequential versus combination chemotherapy with capecitabine, irinotecan, and oxaliplatin in advanced colorectal cancer (CAIRO): a phase III randomised controlled trial. Lancet 2007, 370(9582):135-142.
    • (2007) Lancet , vol.370 , Issue.9582 , pp. 135-142
    • Koopman, M.1    Antonini, N.F.2    Douma, J.3
  • 71
    • 37049022436 scopus 로고    scopus 로고
    • FOLFOX in patients aged between 76 and 80 years with metastatic colorectal cancer: an exploratory cohort of the OPTIMOX1 study
    • Figer A., Perez-Staub N., Carola E., et al. FOLFOX in patients aged between 76 and 80 years with metastatic colorectal cancer: an exploratory cohort of the OPTIMOX1 study. Cancer 2007, 110(12):2666-2671.
    • (2007) Cancer , vol.110 , Issue.12 , pp. 2666-2671
    • Figer, A.1    Perez-Staub, N.2    Carola, E.3
  • 72
    • 0031823713 scopus 로고    scopus 로고
    • Advanced colorectal cancer in the elderly: results of consecutive trials with 5-fluorouracil-based chemotherapy
    • Chiara S., Nobile M.T., Vincenti M., et al. Advanced colorectal cancer in the elderly: results of consecutive trials with 5-fluorouracil-based chemotherapy. Cancer Chemother Pharmacol 1998, 42(4):336-340.
    • (1998) Cancer Chemother Pharmacol , vol.42 , Issue.4 , pp. 336-340
    • Chiara, S.1    Nobile, M.T.2    Vincenti, M.3
  • 73
    • 33748669385 scopus 로고    scopus 로고
    • Pooled analysis of safety and efficacy of oxaliplatin plus fluorouracil/leucovorin administered bimonthly in elderly patients with colorectal cancer
    • [erratum in J Clin Oncol 2008;26(17):2925-6]
    • Goldberg R.M., Tabah-Fisch I., Bleiberg H., et al. Pooled analysis of safety and efficacy of oxaliplatin plus fluorouracil/leucovorin administered bimonthly in elderly patients with colorectal cancer. J Clin Oncol 2006, 24(25):4085-4091. [erratum in J Clin Oncol 2008;26(17):2925-6].
    • (2006) J Clin Oncol , vol.24 , Issue.25 , pp. 4085-4091
    • Goldberg, R.M.1    Tabah-Fisch, I.2    Bleiberg, H.3
  • 74
    • 77950494294 scopus 로고    scopus 로고
    • Effect of bevacizumab in older patients with metastatic colorectal cancer: pooled analysis of four randomized studies
    • Cassidy J., Saltz L.B., Giantonio B.J., et al. Effect of bevacizumab in older patients with metastatic colorectal cancer: pooled analysis of four randomized studies. J Cancer Res Clin Oncol 2010, 136(5):737-743.
    • (2010) J Cancer Res Clin Oncol , vol.136 , Issue.5 , pp. 737-743
    • Cassidy, J.1    Saltz, L.B.2    Giantonio, B.J.3
  • 75
    • 1642588228 scopus 로고    scopus 로고
    • Pancreatic cancer
    • Li D., Xie K., Wolff R., et al. Pancreatic cancer. Lancet 2004, 363(9414):1049-1057.
    • (2004) Lancet , vol.363 , Issue.9414 , pp. 1049-1057
    • Li, D.1    Xie, K.2    Wolff, R.3
  • 76
    • 0034964535 scopus 로고    scopus 로고
    • Pancreatic cancer: the bigger picture
    • Cooperman A.M. Pancreatic cancer: the bigger picture. Surg Clin North Am 2001, 81(3):557-574.
    • (2001) Surg Clin North Am , vol.81 , Issue.3 , pp. 557-574
    • Cooperman, A.M.1
  • 77
    • 8244254377 scopus 로고    scopus 로고
    • Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: a randomized trial
    • Burris H.A., Moore M.J., Andersen J., et al. Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: a randomized trial. J Clin Oncol 1997, 15(6):2403-2413.
    • (1997) J Clin Oncol , vol.15 , Issue.6 , pp. 2403-2413
    • Burris, H.A.1    Moore, M.J.2    Andersen, J.3
  • 78
    • 52149099441 scopus 로고    scopus 로고
    • Fixed-dose rate gemcitabine in elderly patients with advanced pancreatic cancer: an observational study
    • Locher C., Fabre-Guillevin E., Brunetti F., et al. Fixed-dose rate gemcitabine in elderly patients with advanced pancreatic cancer: an observational study. Crit Rev Oncol Hematol 2008, 68(2):178-182.
    • (2008) Crit Rev Oncol Hematol , vol.68 , Issue.2 , pp. 178-182
    • Locher, C.1    Fabre-Guillevin, E.2    Brunetti, F.3
  • 79
    • 41149162302 scopus 로고    scopus 로고
    • Tolerance and efficacy of gemcitabine and gemcitabine-based regimens in elderly patients with advanced pancreatic cancer
    • Marechal R., Demols A., Gay F., et al. Tolerance and efficacy of gemcitabine and gemcitabine-based regimens in elderly patients with advanced pancreatic cancer. Pancreas 2008, 36(3):e16-e21.
    • (2008) Pancreas , vol.36 , Issue.3
    • Marechal, R.1    Demols, A.2    Gay, F.3
  • 80
    • 77950817184 scopus 로고    scopus 로고
    • Gemcitabine therapy for unresectable pancreatic cancer in elderly patients
    • [in Japanese]
    • Katakura Y., Nakahara K., Kobayashi M., et al. Gemcitabine therapy for unresectable pancreatic cancer in elderly patients. Nippon Shokakibyo Gakkai Zasshi 2010, 107(3):396-406. [in Japanese].
    • (2010) Nippon Shokakibyo Gakkai Zasshi , vol.107 , Issue.3 , pp. 396-406
    • Katakura, Y.1    Nakahara, K.2    Kobayashi, M.3
  • 81
    • 79955921754 scopus 로고    scopus 로고
    • FOLFIRINOX versus gemcitabine for metastatic pancreatic cancer
    • Conroy T., Desseigne F., Ychou M., et al. FOLFIRINOX versus gemcitabine for metastatic pancreatic cancer. N Engl J Med 2011, 364(19):1817-1825.
    • (2011) N Engl J Med , vol.364 , Issue.19 , pp. 1817-1825
    • Conroy, T.1    Desseigne, F.2    Ychou, M.3
  • 82
    • 34249933404 scopus 로고    scopus 로고
    • Erlotinib plus gemcitabine compared with gemcitabine alone in patients with advanced pancreatic cancer: a phase III trial of the National Cancer Institute of Canada Clinical Trials Group
    • Moore M.J., Goldstein D., Hamm J., et al. Erlotinib plus gemcitabine compared with gemcitabine alone in patients with advanced pancreatic cancer: a phase III trial of the National Cancer Institute of Canada Clinical Trials Group. J Clin Oncol 2007, 25(15):1960-1966.
    • (2007) J Clin Oncol , vol.25 , Issue.15 , pp. 1960-1966
    • Moore, M.J.1    Goldstein, D.2    Hamm, J.3
  • 83
    • 33745726677 scopus 로고    scopus 로고
    • Perioperative chemotherapy versus surgery alone for resectable gastroesophageal cancer
    • Cunningham D., Allum W.H., Stenning S.P., et al. Perioperative chemotherapy versus surgery alone for resectable gastroesophageal cancer. N Engl J Med 2006, 355(1):11-20.
    • (2006) N Engl J Med , vol.355 , Issue.1 , pp. 11-20
    • Cunningham, D.1    Allum, W.H.2    Stenning, S.P.3
  • 84
    • 33646196614 scopus 로고    scopus 로고
    • Efficacy and tolerability of chemotherapy in elderly patients with advanced oesophago-gastric cancer: a pooled analysis of three clinical trials
    • Trumper M., Ross P.J., Cunningham D., et al. Efficacy and tolerability of chemotherapy in elderly patients with advanced oesophago-gastric cancer: a pooled analysis of three clinical trials. Eur J Cancer 2006, 42(7):827-834.
    • (2006) Eur J Cancer , vol.42 , Issue.7 , pp. 827-834
    • Trumper, M.1    Ross, P.J.2    Cunningham, D.3
  • 85
    • 0028016155 scopus 로고
    • A phase II study in advanced gastro-esophageal cancer using epirubicin and cisplatin in combination with continuous infusion 5-fluorouracil (ECF)
    • 1994
    • Findlay M., Cunningham D., Norman A., et al. A phase II study in advanced gastro-esophageal cancer using epirubicin and cisplatin in combination with continuous infusion 5-fluorouracil (ECF). Ann Oncol 1994, 5(7):609-616. 1994.
    • (1994) Ann Oncol , vol.5 , Issue.7 , pp. 609-616
    • Findlay, M.1    Cunningham, D.2    Norman, A.3
  • 86
    • 33750949065 scopus 로고    scopus 로고
    • Phase III study of docetaxel and cisplatin plus fluorouracil compared with cisplatin and fluorouracil as first-line therapy for advanced gastric cancer: a report of the V325 Study Group
    • Van Cutsem E., Moiseyenko V.M., Tjulandin S., et al. Phase III study of docetaxel and cisplatin plus fluorouracil compared with cisplatin and fluorouracil as first-line therapy for advanced gastric cancer: a report of the V325 Study Group. J Clin Oncol 2006, 24(31):4991-4997.
    • (2006) J Clin Oncol , vol.24 , Issue.31 , pp. 4991-4997
    • Van Cutsem, E.1    Moiseyenko, V.M.2    Tjulandin, S.3
  • 87
    • 38049047178 scopus 로고    scopus 로고
    • Capecitabine and oxaliplatin for advanced esophagogastric cancer
    • Cunningham D., Starling N., Rao S., et al. Capecitabine and oxaliplatin for advanced esophagogastric cancer. N Engl J Med 2008, 358(1):36-46.
    • (2008) N Engl J Med , vol.358 , Issue.1 , pp. 36-46
    • Cunningham, D.1    Starling, N.2    Rao, S.3


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