Variants at the promoter of the interleukin-6 gene are associated with severity and outcome of pneumococcal community-acquired pneumonia

Intensive Care Medicine

Volumn 38, Issue 2, 2012, Pages 256-262

  Martín Loeches, Ignacio ^a,b   Solé Violán, Jordi ^b   Rodríguez De Castro, Felipe ^b,c   García Laorden, M Isabel ^b   Borderías, Luis ^d   Blanquer, José ^e   Rajas, Olga ^f   Briones, M Luisa ^e   Aspa, Javier ^f   Herrera Ramos, Estefanía ^b   Marcos Ramos, José Alberto ^g   Sologuren, Ithaisa ^b   González Quevedo, Nereida ^b   Ferrer Agüero, José María ^b   Noda, Judith ^b   Rodríguez Gallego, Carlos ^b,c  

^a HOSPITAL DE SABADELL   (Spain)

^b HOSPITAL UNIVERSITARIO DE GRAN CANARIA DR NEGRÍN   (Spain)

^c UNIVERSITY OF LAS PALMAS DE GRAN CANARIA   (Spain)

^d HOSPITAL SAN JORGE   (Spain)

^e UNIVERSITY OF VALENCIA   (Spain)

^f HOSPITAL UNIVERSITARIO DE LA PRINCESA   (Spain)

^g HOSPITAL GENERAL DE LANZAROTE   (Spain)

Author keywords

Community acquired pneumonia; IL 6; Polymorphisms; Sepsis; Streptococcus pneumoniae

Indexed keywords

INTERLEUKIN 6;

ADULT RESPIRATORY DISTRESS SYNDROME; ARTICLE; COMMUNITY ACQUIRED PNEUMONIA; COMORBIDITY; CONTROLLED STUDY; DISEASE SEVERITY; FEMALE; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOTYPE; HAEMOPHILUS INFLUENZAE; HAPLOTYPE; HOMOZYGOTE; HUMAN; MAJOR CLINICAL STUDY; MALE; MULTIPLE ORGAN FAILURE; OUTCOME ASSESSMENT; PROMOTER REGION; PROSPECTIVE STUDY; PSEUDOMONAS AERUGINOSA; SEPSIS; SEPTIC SHOCK; SINGLE NUCLEOTIDE POLYMORPHISM; SPAIN; STAPHYLOCOCCUS AUREUS; STREPTOCOCCUS PNEUMONIA; STREPTOCOCCUS PNEUMONIAE; SURVIVAL;

COMMUNITY-ACQUIRED INFECTIONS; FEMALE; HOSPITAL MORTALITY; HUMANS; INTERLEUKIN-6; MALE; MIDDLE AGED; PNEUMONIA, PNEUMOCOCCAL; POLYMORPHISM, GENETIC; PROMOTER REGIONS, GENETIC; PROSPECTIVE STUDIES; SEVERITY OF ILLNESS INDEX;

EID: 84856760448     PISSN: 03424642     EISSN: 14321238     Source Type: Journal    
DOI: 10.1007/s00134-011-2406-y     Document Type: Article

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