The interleukin-6 -174 promoter polymorphism is associated with extrapulmonary bacterial dissemination in Streptococcus pneumoniae infection

Cytokine

Volumn 31, Issue 4, 2005, Pages 324-328

  Schaaf, Bernhard ^a   Rupp, Jan ^a   Müller Steinhardt, Michael ^a   Kruse, Jan ^a   Boehmke, Florian ^a   Maass, Matthias ^a   Zabel, Peter ^a,b   Dalhoff, Klaus ^a  

^a UNIVERSITY OF LÜBECK   (Germany)

^b RESEARCH CENTER BORSTEL   (Germany)

Author keywords

Cytokine; Interleukin 6; Polymorphism; Sepsis; Streptococcus pneumoniae

Indexed keywords

INTERLEUKIN 6;

ADULT; AGED; ALLELE; ARTICLE; BACTERIAL ENDOCARDITIS; BACTERIAL IMMUNITY; BACTERIAL MENINGITIS; CLEARANCE; CONTROLLED STUDY; CYTOKINE RELEASE; DISEASE ACTIVITY; DISEASE COURSE; FEMALE; GENE FREQUENCY; GENETIC POLYMORPHISM; GENOTYPE; HOMOZYGOTE; HUMAN; INFECTION RISK; INFECTION SENSITIVITY; MAJOR CLINICAL STUDY; MALE; MEDICAL PARAMETERS; PRIORITY JOURNAL; PROMOTER REGION; RISK REDUCTION; SEPSIS; STREPTOCOCCUS INFECTION; STREPTOCOCCUS PNEUMONIA; STREPTOCOCCUS PNEUMONIAE;

GENOTYPE; HUMANS; INTERLEUKIN-6; POLYMORPHISM, GENETIC; PROMOTER REGIONS (GENETICS); STREPTOCOCCAL INFECTIONS; STREPTOCOCCUS PNEUMONIAE;

STREPTOCOCCUS PNEUMONIAE;

EID: 23244434834     PISSN: 10434666     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cyto.2005.05.008     Document Type: Article

References (31)

1. H. Georges, O. Leroy, C. Vandenbussche, B. Guery, S. Alfandari, and L. Tronchon Epidemiological features and prognosis of severe community-acquired pneumococcal pneumonia Intensive Care Med 25 1999 198 206
2. W.L. Biffl, E.E. Moore, F.A. Moore, and C.C. Barnett Jr. Interleukin-6 delays neutrophil apoptosis via a mechanism involving platelet-activating factor J Trauma 40 1996 575 578
3. P.G. Mullen, A.C. Windsor, C.J. Walsh, A.A. Fowler 3rd, and H.J. Sugerman Tumor necrosis factor-alpha and interleukin-6 selectively regulate neutrophil function in vitro J Surg Res 58 1995 124 130
4. B.E. Barton IL-6: insights into novel biological activities Clin Immunol Immunopathol 85 1997 16 20
5. D. Aderka, J.M. Le, and J. Vilcek IL-6 inhibits lipopolysaccharide- induced tumor necrosis factor production in cultured human monocytes, U937 cells, and in mice J Immunol 143 1989 3517 3523
6. Z. Xing, J. Gauldie, G. Cox, H. Baumann, M. Jordana, and X.F. Lei IL-6 is an antiinflammatory cytokine required for controlling local or systemic acute inflammatory responses J Clin Invest 101 1998 311 320
7. A.M. Petersen, and B.K. Pedersen The anti-inflammatory effects of exercise J Appl Physiol 98 2005 1154 1162
8. N.S. Ward, A.B. Waxman, R.J. Homer, L.L. Mantell, O. Einarsson, and Y. Du Interleukin-6-induced protection in hyperoxic acute lung injury Am J Respir Cell Mol Biol 22 2000 535 542
9. Y. Bergeron, N. Ouellet, A.M. Deslauriers, M. Simard, M. Olivier, and M.G. Bergeron Cytokine kinetics and other host factors in response to pneumococcal pulmonary infection in mice Infect Immun 66 1998 912 922
10. J. Mohler, E. Azoulay-Dupuis, C. Amory-Rivier, J.X. Mazoit, J.P. Bedos, and V. Rieux Streptococcus pneumoniae strain-dependent lung inflammatory responses in a murine model of pneumococcal pneumonia Intensive Care Med 29 2003 808 816
11. M.S. Dehoux, A. Boutten, J. Ostinelli, N. Seta, M.C. Dombret, and B. Crestani Compartmentalized cytokine production within the human lung in unilateral pneumonia Am J Respir Crit Care Med 150 1994 710 716
12. T. van der Poll, C.V. Keogh, X. Guirao, W.A. Buurman, M. Kopf, and S.F. Lowry Interleukin-6 gene-deficient mice show impaired defense against pneumococcal pneumonia J Infect Dis 176 1997 439 444
13. S.A. Dalrymple, L.A. Lucian, R. Slattery, T. McNeil, D.M. Aud, and S. Fuchino Interleukin-6-deficient mice are highly susceptible to Listeria monocytogenes infection: correlation with inefficient neutrophilia Infect Immun 63 1995 2262 2268
14. Y. Suzuki, S. Rani, O. Liesenfeld, T. Kojima, S. Lim, and T.A. Nguyen Impaired resistance to the development of toxoplasmic encephalitis in interleukin-6-deficient mice Infect Immun 65 1997 2339 2345
15. E. Presterl, T. Staudinger, M. Pettermann, A. Lassnigg, H. Burgmann, and S. Winkler Cytokine profile and correlation to the APACHE III and MPM II scores in patients with sepsis Am J Respir Crit Care Med 156 1997 825 832
16. B. Schluter, C. Raufhake, M. Erren, H. Schotte, F. Kipp, and S. Rust Effect of the interleukin-6 promoter polymorphism (-174 G/C) on the incidence and outcome of sepsis Crit Care Med 30 2002 32 37
17. T.I. Sorensen, G.G. Nielsen, P.K. Andersen, and T.W. Teasdale Genetic and environmental influences on premature death in adult adoptees N Engl J Med 318 1988 727 732
18. B.M. Schaaf, F. Boehmke, H. Esnaashari, U. Seitzer, H. Kothe, and M. Maass Pneumococcal septic shock is associated with the interleukin-10 -1082 gene promoter polymorphism Am J Respir Crit Care Med 168 2003 476 480
19. S. Akira, H. Isshiki, T. Nakajima, S. Kinoshita, Y. Nishio, and S. Natsuka Regulation of expression of the interleukin 6 gene: structure and function of the transcription factor NF-IL6 Ciba Found Symp 167 1992 47 62
20. F.A. Rivera-Chavez, D.L. Peters-Hybki, R.C. Barber, and G.E. O'Keefe Interleukin-6 promoter haplotypes and interleukin-6 cytokine responses Shock 20 2003 218 223
21. D. Fishman, G. Faulds, R. Jeffery, V. Mohamed-Ali, J.S. Yudkin, and S. Humphries The effect of novel polymorphisms in the interleukin-6 (IL-6) gene on IL-6 transcription and plasma IL-6 levels, and an association with systemic-onset juvenile chronic arthritis J Clin Invest 102 1998 1369 1376
22. M. Muller-Steinhardt, L. Fricke, B. Muller, B. Ebel, H. Kirchner, and C. Hartel Cooperative influence of the interleukin-6 promoter polymorphisms -597, -572 and -174 on long-term kidney allograft survival Am J Transplant 4 2004 402 406
23. R.C. Bone, C.J. Grodzin, and R.A. Balk Sepsis: a new hypothesis for pathogenesis of the disease process Chest 112 1997 235 243
24. M.P. Jagger, Z. Huo, and P.G. Riches Inflammatory cytokine (interleukin 6 and tumour necrosis factor alpha) release in a human whole blood system in response to Streptococcus pneumoniae serotype 14 and its capsular polysaccharide Clin Exp Immunol 130 2002 467 474
25. J.M. Stouthard, M. Levi, C.E. Hack, C.H. Veenhof, H.A. Romijn, and H.P. Sauerwein Interleukin-6 stimulates coagulation, not fibrinolysis, in humans Thromb Haemost 76 1996 738 742
26. F. Dallaire, N. Ouellet, Y. Bergeron, V. Turmel, M.C. Gauthier, and M. Simard Microbiological and inflammatory factors associated with the development of pneumococcal pneumonia J Infect Dis 184 2001 292 300
27. T. van der Poll, A. Marchant, C.V. Keogh, M. Goldman, and S.F. Lowry Interleukin-10 impairs host defense in murine pneumococcal pneumonia J Infect Dis 174 1996 994 1000
28. G. Antunes, S.A. Evans, J.L. Lordan, and A.J. Frew Systemic cytokine levels in community-acquired pneumonia and their association with disease severity Eur Respir J 20 2002 990 995
29. J.C. Preiser, D. Schmartz, P. Van der Linden, J. Content, P. Vanden Bussche, and W. Buurman Interleukin-6 administration has no acute hemodynamic or hematologic effect in the dog Cytokine 3 1991 1 4
30. N. Pathan, C.A. Hemingway, A.A. Alizadeh, A.C. Stephens, J.C. Boldrick, and E.E. Oragui Role of interleukin 6 in myocardial dysfunction of meningococcal septic shock Lancet 363 2004 203 209
31. J. Balding, C.M. Healy, W.J. Livingstone, B. White, L. Mynett-Johnson, and M. Cafferkey Genomic polymorphic profiles in an Irish population with meningococcaemia: is it possible to predict severity and outcome of disease? Genes Immun 4 2003 533 540