Protein detection by nanopores equipped with aptamers

Journal of the American Chemical Society

Volumn 134, Issue 5, 2012, Pages 2781-2787

  Rotem, Dvir ^a,c   Jayasinghe, Lakmal ^b   Salichou, Maria ^a   Bayley, Hagan ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b Oxford Nanopore Technologies Ltd   (United Kingdom)

^c HEBREW UNIVERSITY OF JERUSALEM   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

ANALYTE MOLECULES; ANALYTES; APTAMERS; DISSOCIATION RATE CONSTANT; DISULFIDE BONDS; EQUILIBRIUM DISSOCIATION CONSTANT; IONIC CURRENT; MULTIPLE ANALYTES; NANOMOLAR CONCENTRATION; PARALLEL DETECTION; PROTEIN DETECTION; SINGLE CYSTEINE RESIDUE; SMALL MOLECULES; STOCHASTIC SENSORS;

AMINO ACIDS; COVALENT BONDS; DISSOCIATION; OLIGONUCLEOTIDES; RATE CONSTANTS; SENSORS; STOCHASTIC SYSTEMS;

NANOPORES;

ALPHA HEMOLYSIN; APTAMER; CYSTEINE; DNA; OLIGONUCLEOTIDE; THROMBIN;

ANIMAL CELL; ARTICLE; CHEMICAL REACTION KINETICS; DISSOCIATION; DISULFIDE BOND; DNA HYBRIDIZATION; ION CURRENT; NANOPORE; NONHUMAN; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN INTERACTION; SENSOR; SURFACE PLASMON RESONANCE; THERMODYNAMICS;

APTAMERS, NUCLEOTIDE; BIOSENSING TECHNIQUES; MODELS, MOLECULAR; NANOPORES; NANOTECHNOLOGY; PROTEINS; STOCHASTIC PROCESSES; THROMBIN;

EID: 84856729357     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja2105653     Document Type: Article

References (49)

1. Bayley, H.; Martin, C. R. Chem. Rev. 2000, 100, 2575-2594
2. Bayley, H.; Cremer, P. S. Nature 2001, 413, 226-230
3. Dekker, C. Nat. Nanotechnol. 2007, 2, 209-15
4. Sexton, L. T.; Horne, L. P.; Martin, C. R. Mol. Biosyst. 2007, 3, 667-85
5. Howorka, S.; Siwy, Z. Chem. Soc. Rev. 2009, 38, 2360-84
6. Siwy, Z. S.; Howorka, S. Chem. Soc. Rev. 2010, 39, 1115-32
7. Majd, S.; Yusko, E. C.; Billeh, Y. N.; Macrae, M. X.; Yang, J.; Mayer, M. Curr. Opin. Biotechnol. 2010, 21, 439-476
8. Braha, O.; Gu, L.-Q.; Zhou, L.; Lu, X.; Cheley, S.; Bayley, H. Nat. Biotechnol. 2000, 17, 1005-1007
9. Hammerstein, A. F.; Shin, S. H.; Bayley, H. Angew. Chem., Int. Ed. 2010, 49, 5085-5090
10. Braha, O.; Walker, B.; Cheley, S.; Kasianowicz, J. J.; Song, L.; Gouaux, J. E.; Bayley, H. Chem. Biol. 1997, 4, 497-505
11. Gu, L.-Q.; Braha, O.; Conlan, S.; Cheley, S.; Bayley, H. Nature 1999, 398, 686-690
12. Cheley, S.; Gu, L.-Q.; Bayley, H. Chem. Biol. 2002, 9, 829-838
13. Shin, S.-H.; Luchian, T.; Cheley, S.; Braha, O.; Bayley, H. Angew. Chem., Int. Ed. 2002, 41, 3707-3709
14. Howorka, S.; Cheley, S.; Bayley, H. Nat. Biotechnol. 2001, 19, 636-639
15. Movileanu, L.; Howorka, S.; Braha, O.; Bayley, H. Nat. Biotechnol. 2000, 18, 1091-1095
16. Howorka, S.; Nam, J.; Bayley, H.; Kahne, D. Angew. Chem., Int. Ed. 2004, 43, 842-846
17. Xie, H.; Braha, O.; Gu, L.-Q.; Cheley, S.; Bayley, H. Chem. Biol. 2005, 12, 109-120
18. Cheley, S.; Xie, H.; Bayley, H. ChemBioChem 2006, 7, 1923-1927
19. Howorka, S.; Movileanu, L.; Braha, O.; Bayley, H. Proc. Natl. Acad. Sci. U.S.A. 2001, 98, 12996-13001
20. Howorka, S.; Bayley, H. Biophys. J. 2002, 83, 3202-3210
21. Wilson, D. S.; Szostak, J. W. Annu. Rev. Biochem. 1999, 68, 611-47
22. Shamah, S. M.; Healy, J. M.; Cload, S. T. Acc. Chem. Res. 2008, 41, 130-8
23. Cho, E. J.; Lee, J. W.; Ellington, A. D. Annu. Rev. Anal. Chem. 2009, 2, 241-64
24. Nimjee, S. M.; Rusconi, C. P.; Sullenger, B. A. Annu. Rev. Med. 2005, 56, 555-83
25. Tuerk, C.; Gold, L. Science 1990, 249, 505-10
26. Ellington, A. D.; Szostak, J. W. Nature 1990, 346, 818-22
27. Tombelli, S.; Minunni, M.; Mascini, M. Biosens. Bioelectron. 2005, 20, 2424-34
28. Ding, S.; Gao, C.; Gu, L. Q. Anal. Chem. 2009, 81, 6649-55
29. Bock, L. C.; Griffin, L. C.; Latham, J. A.; Vermaas, E. H.; Toole, J. J. Nature 1992, 355, 564-6
30. Macaya, R. F.; Schultze, P.; Smith, F. W.; Roe, J. A.; Feigon, J. Proc. Natl. Acad. Sci. U.S.A. 1993, 90, 3745-9
31. Padmanabhan, K.; Padmanabhan, K. P.; Ferrara, J. D.; Sadler, J. E.; Tulinsky, A. J. Biol. Chem. 1993, 268, 17651-4
32. Wang, K. Y.; McCurdy, S.; Shea, R. G.; Swaminathan, S.; Bolton, P. H. Biochemistry 1993, 32, 1899-904
33. Gouaux, J. E.; Braha, O.; Hobaugh, M. R.; Song, L.; Cheley, S.; Shustak, C.; Bayley, H. Proc. Natl. Acad. Sci. U.S.A. 1994, 91, 12828-12831
34. Shim, J. W.; Gu, L. Q. J. Phys. Chem. B 2008, 112, 8354-60
35. Shim, J. W.; Tan, Q.; Gu, L. Q. Nucleic Acids Res. 2009, 37, 972-82
36. Macaya, R. F.; Waldron, J. A.; Beutel, B. A.; Gao, H.; Joesten, M. E.; Yang, M.; Patel, R.; Bertelsen, A. H.; Cook, A. F. Biochemistry 1995, 34, 4478-92
37. German, I.; Buchanan, D. D.; Kennedy, R. T. Anal. Chem. 1998, 70, 4540-5
38. Berezovski, M.; Nutiu, R.; Li, Y.; Krylov, S. N. Anal. Chem. 2003, 75, 1382-6
39. Huang, C. C.; Cao, Z.; Chang, H. T.; Tan, W. Anal. Chem. 2004, 76, 6973-81
40. Muller, J.; Wulffen, B.; Potzsch, B.; Mayer, G. ChemBioChem 2007, 8, 2223-6
41. Gong, M.; Nikcevic, I.; Wehmeyer, K. R.; Limbach, P. A.; Heineman, W. R. Electrophoresis 2008, 29, 1415-22
42. Hasegawa, H.; Taira, K.-i.; Sode, K.; Ikebukuro, K. Sensors 2008, 8, 1090-1098
43. Ostatna, V.; Vaisocherova, H.; Homola, J.; Hianik, T. Anal. Bioanal. Chem. 2008, 391, 1861-9
44. Pinto, A.; Bermudo Redondo, M. C.; Ozalp, V. C.; O'Sullivan, C. K. Mol. Biosyst. 2009, 5, 548-53
45. Myszka, D. G. Curr. Opin. Biotechnol. 1997, 8, 50-7
46. Baaken, G.; Sondermann, M.; Schlemmer, C.; Ruhe, J.; Behrends, J. C. Lab Chip 2008, 8, 938-44
47. Syeda, R.; Holden, M. A.; Hwang, W. L.; Bayley, H. J. Am. Chem. Soc. 2008, 130, 15543-15548
48. Osaki, T.; Suzuki, H.; Le Pioufle, B.; Takeuchi, S. Anal. Chem. 2009, 81, 9866-70
49. Hall, A. R.; Scott, A.; Rotem, D.; Mehta, K. K.; Bayley, H.; Dekker, C. Nat. Nanotechnol. 2010, 5, 874-877