Drug-induced sleep: Theoretical and practical considerations

Pflugers Archiv European Journal of Physiology

Volumn 463, Issue 1, 2012, Pages 177-186

  Ellenbogen, Jeffrey M ^a,b   Pace Schott, Edward F ^b,c  

^a HARVARD MEDICAL SCHOOL   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c UNIVERSITY OF MASSACHUSETTS   (United States)

Author keywords

Pharmacology; Receptor; Sleep; Sleep apnea; Sleep disorders; Sleep inducing drug; Slow wave sleep

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID B RECEPTOR; 4 HYDROXYBUTYRIC ACID; ACETAZOLAMIDE; AMITRIPTYLINE; ANTIDEPRESSANT AGENT; BENZODIAZEPINE DERIVATIVE; DOPAMINE RECEPTOR STIMULATING AGENT; DOXEPIN; ESZOPICLONE; GABAPENTIN; MELATONIN; MELATONIN RECEPTOR; MIRTAZAPINE; OLANZAPINE; OREXIN; OXYBATE SODIUM; PREGABALIN; QUETIAPINE; RAMELTEON; SEDATIVE AGENT; TASIMELTEON; TEMAZEPAM; TRIMIPRAMINE; VENLAFAXINE; ZOPICLONE;

CIRCADIAN RHYTHM SLEEP DISORDER; DISEASE CLASSIFICATION; DRUG EFFECT; DRUG INDUCED SLEEP; DRUG RESEARCH; HUMAN; INSOMNIA; NARCOLEPSY; NONHUMAN; PARASOMNIA; PRIORITY JOURNAL; REM SLEEP; RESTLESS LEGS SYNDROME; REVIEW; SLEEP; SLEEP APNEA SYNDROME; SLEEP DISORDER; SLOW WAVE SLEEP;

ANIMALS; DYSSOMNIAS; HUMANS; HYPNOTICS AND SEDATIVES; PARASOMNIAS; SLEEP; SLEEP DISORDERS;

EID: 84856727649     PISSN: 00316768     EISSN: 14322013     Source Type: Journal    
DOI: 10.1007/s00424-011-1033-3     Document Type: Review

References (118)

1. American Academy of Sleep Medicine (2005) International classification of sleep disorders, 2nd ed: diagnostic and coding manual. American Academy of Sleep Medicine, Westchester
2. E Anastassiou CA Iatrou N Vlaikidis M Vafiadou G Stamatiou E Plesia L Lyras A Vadalouca 2010 Impact of pregabalin treatment on pain, pain-related sleep interference and general well-being in patients with neuropathic pain: a non-interventional, multicentre, post-marketing study Clin Drug Investig 31 417 426
3. SJ Aton J Seibt MC Dumoulin T Coleman M Shiraishi MG Frank 2009 The sedating antidepressant trazodone impairs sleep-dependent cortical plasticity PLoS One 4 e6078 19568418
4. SJ Aton J Seibt M Dumoulin SK Jha N Steinmetz T Coleman N Naidoo MG Frank 2009 Mechanisms of sleep-dependent consolidation of cortical plasticity Neuron 61 454 466 19217381 1:CAS:528:DC%2BD1MXltFSntb8%3D
5. R Basheer RE Strecker MM Thakkar RW McCarley 2004 Adenosine and sleep-wake regulation Prog Neurobiol 73 379 396 15313333 1:CAS:528: DC%2BD2cXmslamtbw%3D (Pubitemid 39094087)
6. CH Bastien M LeBlanc J Carrier CM Morin 2003 Sleep EEG power spectra, insomnia, and chronic use of benzodiazepines Sleep 26 313 317 12749551 (Pubitemid 39610679)
7. P Beck A Odle T Wallace-Huitt RD Skinner E Garcia-Rill 2008 Modafinil increases arousal determined by P13 potential amplitude: an effect blocked by gap junction antagonists Sleep 31 1647 1654 19090320
8. MT Bianchi 2010 Context dependent benzodiazepine modulation of GABA(A) receptor opening frequency Curr Neuropharmacol 8 10 17 20808542 1:CAS:528:DC%2BC3cXhtl2mtr3O
9. J Black D Pardi CS Hornfeldt N Inhaber 2010 The nightly use of sodium oxybate is associated with a reduction in nocturnal sleep disruption: a double-blind, placebo-controlled study in patients with narcolepsy J Clin Sleep Med 6 596 602 21206549
10. AA Borbely P Mattmann M Loepfe I Strauch D Lehmann 1985 Effect of benzodiazepine hypnotics on all-night sleep EEG spectra Hum Neurobiol 4 189 194 2866173 1:CAS:528:DyaL28XhsV2jsQ%3D%3D (Pubitemid 16214454)
11. J Born 2010 Slow-wave sleep and the consolidation of long-term memory World J Biol Psychiatry 11 Suppl 1 16 21 20509828
12. C Brisbare-Roch J Dingemanse R Koberstein P Hoever H Aissaoui S Flores C Mueller O Nayler J van Gerven SL de Haas P Hess C Qiu S Buchmann M Scherz T Weller W Fischli M Clozel F Jenck 2007 Promotion of sleep by targeting the orexin system in rats, dogs and humans Nat Med 13 150 155 17259994 1:CAS:528:DC%2BD2sXhsVykurw%3D
13. MA Brown C Guilleminault 2011 A review of sodium oxybate and baclofen in the treatment of sleep disorders Curr Pharm Des 17 1430 1435 21476957 1:CAS:528:DC%2BC3MXptlSqtrw%3D
14. EN Brown R Lydic ND Schiff 2010 General anesthesia, sleep, and coma New Engl J Med 363 2638 2650 21190458 1:CAS:528:DC%2BC3MXisVamsA%3D%3D
15. A Brzezinski MG Vangel RJ Wurtman G Norrie I Zhdanova A Ben-Shushan I Ford 2005 Effects of exogenous melatonin on sleep: a meta-analysis Sleep Med Rev 9 41 50 15649737 (Pubitemid 40092917)
16. RM Buijs FA Scheer F Kreier C Yi N Bos VD Goncharuk A Kalsbeek 2006 Organization of circadian functions: interaction with the body Prog Brain Res 153 341 360 16876585 1:CAS:528:DC%2BD28XhtFyru7bL (Pubitemid 44107425)
17. OM Buxton E Marcelli 2010 Short and long sleep are positively associated with obesity, diabetes, hypertension, and cardiovascular disease among adults in the United States Soc Sci Med 71 1027 1036 20621406
18. OM Buxton M Pavlova EW Reid W Wang DC Simonson GK Adler 2010 Sleep restriction for 1week reduces insulin sensitivity in healthy men Diabetes 59 2126 2133 20585000 1:CAS:528:DC%2BC3cXht12kurbN
19. JL Caldwell JA Caldwell 1997 Recovery sleep and performance following sleep deprivation with dextroamphetamine J Sleep Res 6 92 101 9377539 1:STN:280:DyaK1c%2FitVKhtg%3D%3D (Pubitemid 27300267)
20. C Cirelli G Tononi 2008 Is sleep essential? PLoS Biol 6 e216 18752355
21. S Clemens D Rye S Hochman 2006 Restless legs syndrome: revisiting the dopamine hypothesis from the spinal cord perspective Neurology 67 125 130 16832090 (Pubitemid 44305475)
22. S Cohrs A Rodenbeck Z Guan K Pohlmann W Jordan A Meier E Ruther 2004 Sleep-promoting properties of quetiapine in healthy subjects Psychopharmacol Berl 174 421 429 1:CAS:528:DC%2BD2cXls1antrk%3D (Pubitemid 39044301)
23. F Crestani JR Martin H Mohler U Rudolph 2000 Mechanism of action of the hypnotic zolpidem in vivo Br J Pharmacol 131 1251 1254 11090095 1:CAS:528:DC%2BD3cXovFygt7o%3D
24. JM da Roza Davis AL Sharpley PJ Cowen 1992 Slow wave sleep and 5-HT2 receptor sensitivity in generalised anxiety disorder: a pilot study with ritanserin Psychopharmacol Berl 108 387 389
25. Y Dauvilliers I Arnulf E Mignot 2007 Narcolepsy with cataplexy Lancet 369 499 511 17292770 (Pubitemid 46209316)
26. A De Jonghe JC Korevaar BC van Munster SE De Rooij 2010 Effectiveness of melatonin treatment on circadian rhythm disturbances in dementia. Are there implications for delirium? A systematic review Int J Geriatr Psychiatry 25 1201 1208 21086534
27. S Diekelmann J Born 2010 The memory function of sleep Nat Rev Neurosci 11 114 126 20046194 1:CAS:528:DC%2BC3cXktFKi
28. DJ Dijk C Cajochen 1997 Melatonin and the circadian regulation of sleep initiation, consolidation, structure, and the sleep EEG J Biol Rhythm 12 627 635 1:CAS:528:DyaK1cXhsF2luro%3D (Pubitemid 127477099)
29. DJ Eckert AS Jordan P Merchia A Malhotra 2007 Central sleep apnea: pathophysiology and treatment Chest 131 595 607 17296668 (Pubitemid 46280426)
30. PC Emson 2007 GABA(B) receptors: structure and function Prog Brain Res 160 43 57 17499108 1:CAS:528:DC%2BD2sXpsFGqtbk%3D
31. S Ferre I Diamond SR Goldberg L Yao SM Hourani ZL Huang Y Urade I Kitchen 2007 Adenosine A2A receptors in ventral striatum, hypothalamus and nociceptive circuitry implications for drug addiction, sleep and pain Prog Neurobiol 83 332 347 17532111 1:CAS:528:DC%2BD2sXhtlags7zO (Pubitemid 350110608)
32. S Ferre BB Fredholm M Morelli P Popoli K Fuxe 1997 Adenosine-dopamine receptor-receptor interactions as an integrative mechanism in the basal ganglia Trend Neurosci 20 482 487 9347617 1:CAS:528:DyaK2sXmsFKisr4%3D (Pubitemid 27421712)
33. G Fisone A Borgkvist A Usiello 2004 Caffeine as a psychomotor stimulant: mechanism of action Cell Mol Life Sci 61 857 872 15095008 1:CAS:528: DC%2BD2cXls1Grt7k%3D (Pubitemid 38659659)
34. J Gatfield C Brisbare-Roch F Jenck C Boss 2010 Orexin receptor antagonists: a new concept in CNS disorders? ChemMedChem 5 1197 1214 20544785 1:CAS:528:DC%2BC3cXptl2jur8%3D
35. O Gefvert T Lundberg IM Wieselgren M Bergstrom B Langstrom F Wiesel L Lindstrom 2001 D(2) and 5HT(2A) receptor occupancy of different doses of quetiapine in schizophrenia: a PET study Eur Neuropsychopharmacol 11 105 110 11313155 1:CAS:528:DC%2BD3MXislGrs7s%3D (Pubitemid 32335553)
36. P Gerrard R Malcolm 2007 Mechanisms of modafinil: a review of current research Neuropsychiatr Dis Treat 3 349 364 19300566 1:CAS:528: DC%2BD2sXps1WnsLw%3D (Pubitemid 47215010)
37. J Glykys I Mody 2007 Activation of GABAA receptors: views from outside the synaptic cleft Neuron 56 763 770 18054854 1:CAS:528:DC%2BD2sXhsVOrsLbN (Pubitemid 350181356)
38. MM Halassa 2011 Thalamocortical dynamics of sleep: roles of purinergic neuromodulation Semin Cell Dev Biol 22 245 251 21329763 1:CAS:528: DC%2BC3MXktFGlsb0%3D
39. MM Halassa C Florian T Fellin JR Munoz SY Lee T Abel PG Haydon MG Frank 2009 Astrocytic modulation of sleep homeostasis and cognitive consequences of sleep loss Neuron 61 213 219 19186164 1:CAS:528:DC%2BD1MXitVamu74%3D
40. MM Halassa PG Haydon 2010 Integrated brain circuits: astrocytic networks modulate neuronal activity and behavior Annu Rev Physiol 72 335 355 20148679 1:CAS:528:DC%2BC3cXktFKkt7Y%3D
41. MM Halassa JH Siegle JT Ritt JT Ting G Feng CI Moore 2011 Selective optical drive of thalamic reticular nucleus generates thalamic bursts and cortical spindles Nat Neurosci 14 1118 1120 21785436 1:CAS:528: DC%2BC3MXptlamuro%3D
42. SM Hanson EV Morlock KA Satyshur C Czajkowski 2008 Structural requirements for eszopiclone and zolpidem binding to the gamma-aminobutyric acid type-A (GABAA) receptor are different J Med Chem 51 7243 7252 18973287 1:CAS:528:DC%2BD1cXhtlWqtbfO
43. R Hardeland 2010 Investigational melatonin receptor agonists Expert Opin Investig Drug 19 747 764 1:CAS:528:DC%2BC3cXlvFOisLs%3D
44. R Hoque AL Chesson Jr 2010 Pharmacologically induced/exacerbated restless legs syndrome, periodic limb movements of sleep, and REM behavior disorder/REM sleep without atonia: literature review, qualitative scoring, and comparative analysis J Clin Sleep Med 6 79 83 20191944
45. YS Huang C Guilleminault 2009 Narcolepsy: action of two gamma-aminobutyric acid type B agonists, baclofen and sodium oxybate Pediatr Neurol 41 9 16 19520267
46. ZL Huang WM Qu N Eguchi JF Chen MA Schwarzschild BB Fredholm Y Urade O Hayaishi 2005 Adenosine A2A, but not A1, receptors mediate the arousal effect of caffeine Nat Neurosci 8 858 859 15965471 1:CAS:528:DC%2BD2MXlvFWjs74%3D
47. LC Johnson CL Spinweber 1981 Effect of a short-acting benzodiazepine on brain electrical activity during sleep Electroencephalogr Clin Neurophysiol 52 89 97 6166458 1:STN:280:DyaL3M3js1emsA%3D%3D (Pubitemid 11088632)
48. LC Johnson CL Spinweber WF Seidel WC Dement 1983 Sleep spindle and delta changes during chronic use of a short-acting and a long-acting benzodiazepine hypnotic Electroencephalogr Clin Neurophysiol 55 662 667 6189696 1:STN:280:DyaL3s3gvFegsw%3D%3D (Pubitemid 13099642)
49. KM Kahlig A Galli 2003 Regulation of dopamine transporter function and plasma membrane expression by dopamine, amphetamine, and cocaine Eur J Pharmacol 479 153 158 14612146 1:CAS:528:DC%2BD3sXovVGntb8%3D (Pubitemid 37377884)
50. U Koch AK Magnusson 2009 Unconventional GABA release: mechanisms and function Curr Opin Neurobiol 19 305 310 19375301 1:CAS:528:DC%2BD1MXhtVent7%2FL
51. JM Krueger DM Rector S Roy HP Van Dongen G Belenky J Panksepp 2008 Sleep as a fundamental property of neuronal assemblies Nat Rev Neurosci 9 910 919 18985047 1:CAS:528:DC%2BD1cXhtl2gsbzF
52. AD Krystal HH Durrence M Scharf P Jochelson R Rogowski E Ludington T Roth 2010 Efficacy and safety of doxepin 1 mg and 3 mg in a 12-week sleep laboratory and outpatient trial of elderly subjects with chronic primary insomnia Sleep 33 1553 1561 21102997
53. C Lamus CJ Long MS Hamalainen EN Brown PL Purdon 2007 Parameter estimation and dynamic source localization for the magnetoencephalography (Meg) inverse problem. Proceedings/IEEE International Symposium on Biomedical Imaging: from nano to macro IEEE Int Symp Biomed Imaging 2007 1092 1095 (Pubitemid 350141283)
54. HP Landolt R Wehrle 2009 Antagonism of serotonergic 5-HT2A/2C receptors: mutual improvement of sleep, cognition and mood? Eur J Neurosci 29 1795 1809 19473234
55. T Lange S Dimitrov T Bollinger S Diekelmann J Born 2011 Sleep after vaccination boosts immunological memory J Immunol 187 283 290 21632713 1:CAS:528:DC%2BC3MXnvValsLw%3D
56. A Lankford S Ancoli-Israel 2007 Indiplon: the development of a novel therapy for the treatment of sleep onset and sleep maintenance insomnia Int J Clin Pract 61 1037 1045 17386060 1:STN:280:DC%2BD2s3pt1CisQ%3D%3D (Pubitemid 46744062)
57. M Lazarus HY Shen Y Cherasse WM Qu ZL Huang CE Bass R Winsky-Sommerer K Semba BB Fredholm D Boison O Hayaishi Y Urade JF Chen 2011 Arousal effect of caffeine depends on adenosine A2A receptors in the shell of the nucleus accumbens J Neurosci 31 10067 10075 21734299 1:CAS:528:DC%2BC3MXptFWqsrg%3D
58. A Malhotra RL Owens 2010 What is central sleep apnea? Respir Care 55 1168 1178 20799999
59. AG Mayers DS Baldwin 2005 Antidepressants and their effect on sleep Hum Psychopharmacol 20 533 559 16229049 1:CAS:528:DC%2BD28Xot1entg%3D%3D (Pubitemid 43056116)
60. SM McKinney TT Dang-Vu OM Buxton JM Solet JM Ellenbogen 2011 Covert waking brain activity reveals instantaneous sleep depth PLoS One 6 e17351 21408616 1:CAS:528:DC%2BC3MXjtFymsL4%3D
61. E Mignot 2008 Why we sleep: the temporal organization of recovery PLoS Biol 6 e106 18447584
62. E Mignot S Nishino 2005 Emerging therapies in narcolepsy-cataplexy Sleep 28 754 763 16477963 (Pubitemid 40803472)
63. HA Mitchell JW Bogenpohl LC Liles MP Epstein D Bozyczko-Coyne M Williams D Weinshenker 2008 Behavioral responses of dopamine beta-hydroxylase knockout mice to modafinil suggest a dual noradrenergic-dopaminergic mechanism of action Pharmacol Biochem Behav 91 217 222 18703079 1:CAS:528:DC%2BD1cXht12ltrbL
64. H Mohler 2006 GABA(A) receptor diversity and pharmacology Cell Tissue Res 326 505 516 16937111 1:STN:280:DC%2BD28rmslWrsA%3D%3D
65. H Mohler JM Fritschy U Rudolph 2002 A new benzodiazepine pharmacology J Pharmacol Exp Ther 300 2 8 11752090 1:CAS:528:DC%2BD38Xht1WhtA%3D%3D (Pubitemid 34028501)
66. M Mor S Rivara D Pala A Bedini G Spadoni G Tarzia 2010 Recent advances in the development of melatonin MT(1) and MT(2) receptor agonists Expert Opin Ther Pat 20 1059 1077 20533893 1:CAS:528:DC%2BC3cXpt1SltLk%3D
67. PT Morgan RT Malison 2008 Pilot study of lorazepam and tiagabine effects on sleep, motor learning, and impulsivity in cocaine abstinence Am J Drug Alcohol Abus 34 692 702
68. PT Morgan E Pace-Schott B Pittman R Stickgold RT Malison 2010 Normalizing effects of modafinil on sleep in chronic cocaine users Am J Psychiatry 167 331 340 20080983
69. DN Neubauer 2010 Almorexant, a dual orexin receptor antagonist for the treatment of insomnia Curr Opin Investig Drug 11 101 110 1:CAS:528: DC%2BC3cXnt1Kgsbc%3D
70. AN Nicholson AJ Belyavin PA Pascoe 1989 Modulation of rapid eye movement sleep in humans by drugs that modify monoaminergic and purinergic transmission Neuropsychopharmacology 2 131 143 2568115 1:CAS:528:DyaL1MXkvFShur4%3D (Pubitemid 19181606)
71. RW Olsen W Sieghart 2009 GABA A receptors: subtypes provide diversity of function and pharmacology Neuropharmacology 56 141 148 18760291 1:CAS:528:DC%2BD1MXhsVGnug%3D%3D
72. SR Pandi-Perumal I Trakht V Srinivasan DW Spence GJ Maestroni N Zisapel DP Cardinali 2008 Physiological effects of melatonin: role of melatonin receptors and signal transduction pathways Prog Neurobiol 85 335 353 18571301 1:CAS:528:DC%2BD1cXosVymurY%3D
73. HC Pape K Jungling T Seidenbecher J Lesting RK Reinscheid 2010 Neuropeptide S: a transmitter system in the brain regulating fear and anxiety Neuropharmacology 58 29 34 19523478 1:CAS:528:DC%2BD1MXhtlGitrbL
74. D Pardi J Black 2006 Gamma-hydroxybutyrate/sodium oxybate: neurobiology, and impact on sleep and wakefulness CNS Drug 20 993 1018 1:CAS:528: DC%2BD2sXhtlSmt74%3D (Pubitemid 44912708)
75. W Paulus ED Schomburg 2006 Dopamine and the spinal cord in restless legs syndrome: does spinal cord physiology reveal a basis for augmentation? Sleep Med Rev 10 185 196 16762808 (Pubitemid 43817595)
76. Pizzagalli DA (2007) Electroencephalography and high-density electrophysiological source localization. In: Cacioppo JT, Tassinaru GG (eds) Handbook of psychophysiology. Cambridge University Press, Cambridge, pp 56-84
77. T Porkka-Heiskanen AV Kalinchuk 2011 Adenosine, energy metabolism and sleep homeostasis Sleep Med Rev 15 123 135 20970361
78. WM Qu ZL Huang XH Xu N Matsumoto Y Urade 2008 Dopaminergic D1 and D2 receptors are essential for the arousal effect of modafinil J Neurosci 28 8462 8469 18716204 1:CAS:528:DC%2BD1cXhtVGqsLbL
79. D Riemann U Voderholzer S Cohrs A Rodenbeck G Hajak E Ruther MH Wiegand G Laakmann T Baghai W Fischer M Hoffmann F Hohagen G Mayer M Berger 2002 Trimipramine in primary insomnia: results of a polysomnographic double-blind controlled study Pharmacopsychiatry 35 165 174 12237787 1:CAS:528: DC%2BD38Xot1WhtLo%3D
80. T Roehrs T Roth 2010 Drug-related sleep stage changes: functional significance and clinical relevance Sleep Med Clin 5 559 570 21344068
81. T Roehrs T Roth 2011 Drug-related sleep stage changes: functional significance and clinical relevance Sleep Med Clin 5 559 570
82. T Roehrs G Vogel F Vogel R Wittig F Zorick C Paxton J Lamphere T Roth 1986 Dose effects of temazepam tablets on sleep Drugs under exp clin res 12 693 699 1:STN:280:DyaL2s%2FgsVShsw%3D%3D (Pubitemid 16076713)
83. T Roth JR Schwartz M Hirshkowitz MK Erman JM Dayno S Arora 2007 Evaluation of the safety of modafinil for treatment of excessive sleepiness J Clin Sleep Med 3 595 602 17993041 (Pubitemid 350207103)
84. T Roth KP Wright Jr J Walsh 2006 Effect of tiagabine on sleep in elderly subjects with primary insomnia: a randomized, double-blind, placebo-controlled study Sleep 29 335 341 16553019 (Pubitemid 44019956)
85. PP Roy-Byrne 2005 The GABA-benzodiazepine receptor complex: structure, function, and role in anxiety J Clin Psychiatry 66 Suppl 2 14 20 15762815 1:CAS:528:DC%2BD2MXislagtb0%3D (Pubitemid 40343676)
86. U Rudolph F Crestani D Benke I Brunig JA Benson JM Fritschy JR Martin H Bluethmann H Mohler 1999 Benzodiazepine actions mediated by specific gamma-aminobutyric acid(A) receptor subtypes Nature 401 796 800 10548105 1:CAS:528:DyaK1MXntFaru70%3D
87. IJ Russell LJ Crofford T Leon JC Cappelleri AG Bushmakin E Whalen JA Barrett A Sadosky 2009 The effects of pregabalin on sleep disturbance symptoms among individuals with fibromyalgia syndrome Sleep Med 10 604 610 19410509
88. JP Saboisky NL Chamberlin A Malhotra 2009 Potential therapeutic targets in obstructive sleep apnoea Expert opin ther target 13 795 809 1:CAS:528:DC%2BD1MXnt1ynsLY%3D
89. T Sakurai 2007 The neural circuit of orexin (hypocretin): maintaining sleep and wakefulness Nat Rev Neurosci 8 171 181 17299454 1:CAS:528: DC%2BD2sXhvVyqu7s%3D (Pubitemid 46294664)
90. CB Saper PM Fuller NP Pedersen J Lu TE Scammell 2010 Sleep state switching Neuron 68 1023 1042 21172606 1:CAS:528:DC%2BC3cXhsFykt7rO
91. MJ Sateia P Kirby-Long JL Taylor 2008 Efficacy and clinical safety of ramelteon: an evidence-based review Sleep Med Rev 12 319 332 18603221 (Pubitemid 351899319)
92. TE Scammell 2003 The neurobiology, diagnosis, and treatment of narcolepsy Ann Neurol 53 154 166 12557281 (Pubitemid 36163996)
93. TE Scammell CJ Winrow 2011 Orexin receptors: pharmacology and therapeutic opportunities Annu Rev Pharmacol Toxicol 51 243 266 21034217 1:CAS:528:DC%2BC3MXisFOju74%3D
94. J Seibt SJ Aton SK Jha T Coleman MC Dumoulin MG Frank 2008 The non-benzodiazepine hypnotic zolpidem impairs sleep-dependent cortical plasticity Sleep 31 1381 1391 18853935
95. AL Sharpley CM Vassallo PJ Cowen 2000 Olanzapine increases slow-wave sleep: evidence for blockade of central 5-HT(2C) receptors in vivo Biol Psychiatry 47 468 470 10704958 1:CAS:528:DC%2BD3cXhsFOht74%3D (Pubitemid 30110618)
96. V Srinivasan J Singh SR Pandi-Perumal GM Brown DW Spence DP Cardinali 2010 Jet lag, circadian rhythm sleep disturbances, and depression: the role of melatonin and its analogs Adv Ther 27 796 813 20827520 1:CAS:528:DC%2BC3MXlvVGi
97. SM Stahl 2002 Selective actions on sleep or anxiety by exploiting GABA-A/benzodiazepine receptor subtypes J Clin Psychiatry 63 179 180 11926714 (Pubitemid 34407074)
98. Y Takemura A Yamashita H Horiuchi M Furuya M Yanase K Niikura S Imai N Hatakeyama H Kinoshita Y Tsukiyama E Senba M Matoba N Kuzumaki M Yamazaki T Suzuki M Narita 2011 Effects of gabapentin on brain hyperactivity related to pain and sleep disturbance under a neuropathic pain-like state using fMRI and brain wave analysis Synapse 65 668 676 21162109 1:CAS:528:DC%2BC3MXksVKgt7o%3D
99. X Tan S Uchida M Matsuura K Nishihara T Kojima 2003 Long-, intermediate- and short-acting benzodiazepine effects on human sleep EEG spectra Psychiatry Clin Neurosci 57 97 104 12519461 1:CAS:528:DC%2BD3sXjs1ems70%3D (Pubitemid 36227555)
100. CP Taylor 2009 Mechanisms of analgesia by gabapentin and pregabalin-calcium channel alpha2-delta [Cavalpha2-delta] ligands Pain 142 13 16 19128880 1:CAS:528:DC%2BD1MXit1aht7c%3D
101. C Trenkwalder W Paulus AS Walters 2005 The restless legs syndrome Lancet Neurol 4 465 475 16033689 1:CAS:528:DC%2BD2MXpsFWrt74%3D (Pubitemid 40982457)
102. TG Tzellos KA Toulis DG Goulis G Papazisis VA Zampeli A Vakfari D Kouvelas 2010 Gabapentin and pregabalin in the treatment of fibromyalgia: a systematic review and a meta-analysis J Clin Pharm Ther 35 639 656 21054455 1:CAS:528:DC%2BC3cXhs1aisL3J
103. D Ulrich B Bettler 2007 GABA(B) receptors: synaptic functions and mechanisms of diversity Curr Opin Neurobiol 17 298 303 17433877 1:CAS:528:DC%2BD2sXmtlagsr8%3D (Pubitemid 46880321)
104. M Uusi-Oukari ER Korpi 2010 Regulation of GABA(A) receptor subunit expression by pharmacological agents Pharmacol Rev 62 97 135 20123953 1:CAS:528:DC%2BC3cXhsVSltbnJ
105. IM van Geijlswijk HP Korzilius MG Smits 2010 The use of exogenous melatonin in delayed sleep phase disorder: a meta-analysis Sleep 33 1605 1614 21120122
106. J Vienne B Bettler P Franken M Tafti 2010 Differential effects of GABAB receptor subtypes, {gamma}-hydroxybutyric acid, and baclofen on EEG activity and sleep regulation J Neurosci 30 14194 14204 20962240 1:CAS:528: DC%2BC3cXhtlyqtLnM
107. ND Volkow JS Fowler J Logan D Alexoff W Zhu F Telang GJ Wang M Jayne JM Hooker C Wong B Hubbard P Carter D Warner P King C Shea Y Xu L Muench K Apelskog-Torres 2009 Effects of modafinil on dopamine and dopamine transporters in the male human brain: clinical implications Jama 301 1148 1154 19293415 1:CAS:528:DC%2BD1MXjsVOlsbY%3D
108. KA Wafford B Ebert 2006 Gaboxadol-a new awakening in sleep Curr Opin Pharmacol 6 30 36 16368265 1:CAS:528:DC%2BD28XmsVyhtA%3D%3D
109. J Wagner ML Wagner 2000 Non-benzodiazepines for the treatment of insomnia Sleep Med Rev 4 551 581 12531036 (Pubitemid 32104352)
110. MP Walker 2009 The role of slow wave sleep in memory processing J Clin Sleep Med 5 S20 S26 19998871
111. JK Walsh AC Randazzo K Stone R Eisenstein SD Feren S Kajy P Dickey T Roehrs T Roth PK Schweitzer 2006 Tiagabine is associated with sustained attention during sleep restriction: evidence for the value of slow-wave sleep enhancement? Sleep 29 433 443 16676776 (Pubitemid 44019932)
112. JK Walsh G Zammit PK Schweitzer J Ondrasik T Roth 2006 Tiagabine enhances slow wave sleep and sleep maintenance in primary insomnia Sleep Med 7 155 161 16260179
113. CJ Watson HA Baghdoyan R Lydic 2010 Neuropharmacology of sleep and wakefulness Sleep Med Clin 5 513 528 21278831
114. CJ Winrow AL Gotter CD Cox SM Doran PL Tannenbaum MJ Breslin SL Garson SV Fox CM Harrell J Stevens DR Reiss D Cui PJ Coleman JJ Renger 2011 Promotion of sleep by suvorexant-a novel dual orexin receptor antagonist J Neurogenet 25 52 61 21473737 1:CAS:528:DC%2BC3MXmtVWlsrg%3D
115. R Winsky-Sommerer 2009 Role of GABAA receptors in the physiology and pharmacology of sleep Eur J Neurosci 29 1779 1794 19473233
116. JP Wisor KS Eriksson 2005 Dopaminergic-adrenergic interactions in the wake promoting mechanism of modafinil Neuroscience 132 1027 1034 15857707 1:CAS:528:DC%2BD2MXjs1Ghurc%3D (Pubitemid 40602537)
117. IV Zhdanova 2005 Melatonin as a hypnotic: pro Sleep Med Rev 9 51 65 15649738 (Pubitemid 40092918)
118. NN Zheleznova A Sedelnikova DS Weiss 2009 Function and modulation of delta-containing GABA(A) receptors Psychoneuroendocrinology 34 Suppl 1 S67 S73 19766404 1:CAS:528:DC%2BD1MXhsFGrtLfM