-
1
-
-
5444238109
-
Genetic and epigenetic modulation of telomerase activity in development and disease
-
L. Liu, S. Lai, L.G. Andrews, and T.O. Tollefsbol Genetic and epigenetic modulation of telomerase activity in development and disease Gene 340 1 2004 1 10
-
(2004)
Gene
, vol.340
, Issue.1
, pp. 1-10
-
-
Liu, L.1
Lai, S.2
Andrews, L.G.3
Tollefsbol, T.O.4
-
2
-
-
70349887763
-
Physiology Nobel. U.S. researchers recognized for work on telomerase
-
G. Vogel, and E. Pennisi Physiology Nobel. U.S. researchers recognized for work on telomerase Science 326 5950 2009 212 213
-
(2009)
Science
, vol.326
, Issue.5950
, pp. 212-213
-
-
Vogel, G.1
Pennisi, E.2
-
3
-
-
70349941114
-
Chromosome protection scoops Nobel
-
A. Abbott Chromosome protection scoops Nobel Nature 461 7265 2009 706 707
-
(2009)
Nature
, vol.461
, Issue.7265
, pp. 706-707
-
-
Abbott, A.1
-
4
-
-
64749109630
-
Genomic amplification of the human telomerase RNA gene for differential diagnosis of cervical disorders
-
Z. Tu, A. Zhang, R. Wu, J. Jiang, Y. Li, and N. Wulan Genomic amplification of the human telomerase RNA gene for differential diagnosis of cervical disorders Cancer Genet Cytogenet 191 1 2009 10 16
-
(2009)
Cancer Genet Cytogenet
, vol.191
, Issue.1
, pp. 10-16
-
-
Tu, Z.1
Zhang, A.2
Wu, R.3
Jiang, J.4
Li, Y.5
Wulan, N.6
-
5
-
-
0035897568
-
Activity, function, and gene regulation of the catalytic subunit of telomerase (hTERT)
-
J.C. Poole, L.G. Andrews, and T.O. Tollefsbol Activity, function, and gene regulation of the catalytic subunit of telomerase (hTERT) Gene 269 1-2 2001 1 12
-
(2001)
Gene
, vol.269
, Issue.12
, pp. 1-12
-
-
Poole, J.C.1
Andrews, L.G.2
Tollefsbol, T.O.3
-
6
-
-
0032485416
-
Telomerase activity is restored in human cells by ectopic expression of hTERT (hEST2), the catalytic subunit of telomerase
-
C.M. Counter, M. Meyerson, E.N. Eaton, L.W. Ellisen, S.D. Caddle, and D.A. Haber Telomerase activity is restored in human cells by ectopic expression of hTERT (hEST2), the catalytic subunit of telomerase Oncogene 16 9 1998 1217 1222
-
(1998)
Oncogene
, vol.16
, Issue.9
, pp. 1217-1222
-
-
Counter, C.M.1
Meyerson, M.2
Eaton, E.N.3
Ellisen, L.W.4
Caddle, S.D.5
Haber, D.A.6
-
7
-
-
0030659644
-
Reconstitution of human telomerase with the template RNA component hTR and the catalytic protein subunit hTRT
-
S.L. Weinrich, R. Pruzan, L. Ma, M. Ouellette, V.M. Tesmer, and S.E. Holt Reconstitution of human telomerase with the template RNA component hTR and the catalytic protein subunit hTRT Nat Genet 17 4 1997 498 502
-
(1997)
Nat Genet
, vol.17
, Issue.4
, pp. 498-502
-
-
Weinrich, S.L.1
Pruzan, R.2
Ma, L.3
Ouellette, M.4
Tesmer, V.M.5
Holt, S.E.6
-
8
-
-
0037148401
-
Regulation of the human telomerase reverse transcriptase gene
-
A.L. Ducrest, H. Szutorisz, J. Lingner, and M. Nabholz Regulation of the human telomerase reverse transcriptase gene Oncogene 21 4 2002 541 552
-
(2002)
Oncogene
, vol.21
, Issue.4
, pp. 541-552
-
-
Ducrest, A.L.1
Szutorisz, H.2
Lingner, J.3
Nabholz, M.4
-
9
-
-
35948943138
-
Mechanisms of action of TGF-beta in cancer: Evidence for Smad3 as a repressor of the hTERT gene
-
H. Li, and J.P. Liu Mechanisms of action of TGF-beta in cancer: evidence for Smad3 as a repressor of the hTERT gene Ann N Y Acad Sci 1114 2007 56 68
-
(2007)
Ann N y Acad Sci
, vol.1114
, pp. 56-68
-
-
Li, H.1
Liu, J.P.2
-
10
-
-
49749139661
-
Understanding and exploiting hTERT promoter regulation for diagnosis and treatment of human cancers
-
S. Kyo, M. Takakura, T. Fujiwara, and M. Inoue Understanding and exploiting hTERT promoter regulation for diagnosis and treatment of human cancers Cancer Sci 99 8 2008 1528 1538
-
(2008)
Cancer Sci
, vol.99
, Issue.8
, pp. 1528-1538
-
-
Kyo, S.1
Takakura, M.2
Fujiwara, T.3
Inoue, M.4
-
11
-
-
0033558281
-
Cloning and characterization of the promoter region of human telomerase reverse transcriptase gene
-
I. Horikawa, P.L. Cable, C. Afshari, and J.C. Barrett Cloning and characterization of the promoter region of human telomerase reverse transcriptase gene Cancer Res 59 4 1999 826 830
-
(1999)
Cancer Res
, vol.59
, Issue.4
, pp. 826-830
-
-
Horikawa, I.1
Cable, P.L.2
Afshari, C.3
Barrett, J.C.4
-
12
-
-
0242574736
-
Hypermethylation of the hTERT promoter inhibits the expression of telomerase activity in normal oral fibroblasts and senescent normal oral keratinocytes
-
K.H. Shin, M.K. Kang, E. Dicterow, and N.H. Park Hypermethylation of the hTERT promoter inhibits the expression of telomerase activity in normal oral fibroblasts and senescent normal oral keratinocytes Br J Cancer 89 8 2003 1473 1478
-
(2003)
Br J Cancer
, vol.89
, Issue.8
, pp. 1473-1478
-
-
Shin, K.H.1
Kang, M.K.2
Dicterow, E.3
Park, N.H.4
-
13
-
-
0041630614
-
Control mechanisms in the regulation of telomerase reverse transcriptase expression in differentiating human teratocarcinoma cells
-
N.G. Lopatina, J.C. Poole, S.N. Saldanha, N.J. Hansen, J.S. Key, and M.A. Pita Control mechanisms in the regulation of telomerase reverse transcriptase expression in differentiating human teratocarcinoma cells Biochem Biophys Res Commun 306 3 2003 650 659
-
(2003)
Biochem Biophys Res Commun
, vol.306
, Issue.3
, pp. 650-659
-
-
Lopatina, N.G.1
Poole, J.C.2
Saldanha, S.N.3
Hansen, N.J.4
Key, J.S.5
Pita, M.A.6
-
14
-
-
3342913667
-
Epigenetic regulation of human telomerase reverse transcriptase promoter activity during cellular differentiation
-
L. Liu, S.N. Saldanha, M.S. Pate, L.G. Andrew, and T.O. Tollefsbol Epigenetic regulation of human telomerase reverse transcriptase promoter activity during cellular differentiation Genes Chromosomes Cancer 41 1 2004 26 37
-
(2004)
Genes Chromosomes Cancer
, vol.41
, Issue.1
, pp. 26-37
-
-
Liu, L.1
Saldanha, S.N.2
Pate, M.S.3
Andrew, L.G.4
Tollefsbol, T.O.5
-
15
-
-
0033572577
-
DNA methylation analysis of the promoter region of the human telomerase reverse transcriptase (hTERT) gene
-
T.R. Devereux, I. Horikawa, C.H. Anna, L.A. Annab, C.A. Afshari, and J.C. Barrett DNA methylation analysis of the promoter region of the human telomerase reverse transcriptase (hTERT) gene Cancer Res 59 24 1999 6087 6090
-
(1999)
Cancer Res
, vol.59
, Issue.24
, pp. 6087-6090
-
-
Devereux, T.R.1
Horikawa, I.2
Anna, C.H.3
Annab, L.A.4
Afshari, C.A.5
Barrett, J.C.6
-
16
-
-
0033953573
-
Methylation of the human telomerase gene CpG island
-
S.K. Dessain, H. Yu, R.R. Reddel, R.L. Beijersbergen, and R.A. Weinberg Methylation of the human telomerase gene CpG island Cancer Res 60 3 2000 537 541
-
(2000)
Cancer Res
, vol.60
, Issue.3
, pp. 537-541
-
-
Dessain, S.K.1
Yu, H.2
Reddel, R.R.3
Beijersbergen, R.L.4
Weinberg, R.A.5
-
17
-
-
0036782079
-
Hypermethylation of the human telomerase catalytic subunit (hTERT) gene correlates with telomerase activity
-
I. Guilleret, P. Yan, F. Grange, R. Braunschweig, F.T. Bosman, and J. Benhattar Hypermethylation of the human telomerase catalytic subunit (hTERT) gene correlates with telomerase activity Int J Cancer 101 4 2002 335 341
-
(2002)
Int J Cancer
, vol.101
, Issue.4
, pp. 335-341
-
-
Guilleret, I.1
Yan, P.2
Grange, F.3
Braunschweig, R.4
Bosman, F.T.5
Benhattar, J.6
-
18
-
-
33846422373
-
TERT is expressed in cancer cell lines despite promoter DNA methylation by preservation of unmethylated DNA and active chromatin around the transcription start site
-
R.L. Zinn, K. Pruitt, S. Eguchi, S.B. Baylin, and J.G. Herman TERT is expressed in cancer cell lines despite promoter DNA methylation by preservation of unmethylated DNA and active chromatin around the transcription start site Cancer Res 67 1 2007 194 201
-
(2007)
Cancer Res
, vol.67
, Issue.1
, pp. 194-201
-
-
Zinn, R.L.1
Pruitt, K.2
Eguchi, S.3
Baylin, S.B.4
Herman, J.G.5
-
19
-
-
0032840918
-
Human papillomavirus is a necessary cause of invasive cervical cancer worldwide
-
J.M. Walboomers, M.V. Jacobs, M.M. Manos, F.X. Bosch, J.A. Kummer, and K.V. Shah Human papillomavirus is a necessary cause of invasive cervical cancer worldwide J Pathol 189 1 1999 12 19
-
(1999)
J Pathol
, vol.189
, Issue.1
, pp. 12-19
-
-
Walboomers, J.M.1
Jacobs, M.V.2
Manos, M.M.3
Bosch, F.X.4
Kummer, J.A.5
Shah, K.V.6
-
20
-
-
0034947881
-
E box-dependent activation of telomerase by human papillomavirus type 16, E6 does not require induction of c-myc
-
L. Gewin, and D.A. Galloway E box-dependent activation of telomerase by human papillomavirus type 16, E6 does not require induction of c-myc J Virol 75 15 2001 7198 7201
-
(2001)
J Virol
, vol.75
, Issue.15
, pp. 7198-7201
-
-
Gewin, L.1
Galloway, D.A.2
-
21
-
-
0035043423
-
Transcriptional activation of the telomerase hTERT gene by human papillomavirus type 16, E6 oncoprotein
-
T. Veldman, I. Horikawa, J.C. Barrett, and R. Schlegel Transcriptional activation of the telomerase hTERT gene by human papillomavirus type 16, E6 oncoprotein J Virol 75 9 2001 4467 4472
-
(2001)
J Virol
, vol.75
, Issue.9
, pp. 4467-4472
-
-
Veldman, T.1
Horikawa, I.2
Barrett, J.C.3
Schlegel, R.4
-
22
-
-
1942508923
-
Methylation status and expression of human telomerase reverse transcriptase in ovarian and cervical cancer
-
A. Widschwendter, H.M. Müller, M.M. Hubalek, A. Wiedemair, H. Fiegl, and G. Goebel Methylation status and expression of human telomerase reverse transcriptase in ovarian and cervical cancer Gynecol Oncol 93 2 2004 407 416
-
(2004)
Gynecol Oncol
, vol.93
, Issue.2
, pp. 407-416
-
-
Widschwendter, A.1
Müller, H.M.2
Hubalek, M.M.3
Wiedemair, A.4
Fiegl, H.5
Goebel, G.6
-
23
-
-
0037148289
-
Analysis of telomerase as a diagnostic biomarker of cervical dysplasia and carcinoma
-
E.A. Jarboe, K.L. Liaw, L.C. Thompson, D.E. Heinz, P.L. Baker, and J.A. McGregor Analysis of telomerase as a diagnostic biomarker of cervical dysplasia and carcinoma Oncogene 21 4 2002 664 673
-
(2002)
Oncogene
, vol.21
, Issue.4
, pp. 664-673
-
-
Jarboe, E.A.1
Liaw, K.L.2
Thompson, L.C.3
Heinz, D.E.4
Baker, P.L.5
McGregor, J.A.6
-
24
-
-
68249160070
-
Correlation of promoter hypermethylation in hTERT, DAPK and MGMT genes with cervical oncogenesis progression
-
D. Iliopoulos, P. Oikonomou, I. Messinis, and A. Tsezou Correlation of promoter hypermethylation in hTERT, DAPK and MGMT genes with cervical oncogenesis progression Oncol Rep 22 1 2009 199 204
-
(2009)
Oncol Rep
, vol.22
, Issue.1
, pp. 199-204
-
-
Iliopoulos, D.1
Oikonomou, P.2
Messinis, I.3
Tsezou, A.4
-
25
-
-
33751510703
-
Genomic integration of oncogenic HPV and gain of the human telomerase gene TERC at 3q26 are strongly associated events in the progression of uterine cervical dysplasia to invasive cancer
-
A.H. Hopman, W. Theelen, P.P. Hommelberg, M.A.F. Kamps, C.S. Herrington, and L.E. Morrison Genomic integration of oncogenic HPV and gain of the human telomerase gene TERC at 3q26 are strongly associated events in the progression of uterine cervical dysplasia to invasive cancer J Pathol 210 4 2006 412 419
-
(2006)
J Pathol
, vol.210
, Issue.4
, pp. 412-419
-
-
Hopman, A.H.1
Theelen, W.2
Hommelberg, P.P.3
Kamps, M.A.F.4
Herrington, C.S.5
Morrison, L.E.6
-
26
-
-
78049407607
-
Detection of TERC amplification in cervical epithelial cells for the diagnosis of high-grade cervical lesions and invasive cancer: A multicenter study in China
-
J. Jiang, L.H. Wei, Y.L. Li, R.F. Wu, X. Xie, and Y.J. Feng Detection of TERC amplification in cervical epithelial cells for the diagnosis of high-grade cervical lesions and invasive cancer: a multicenter study in China J Mol Diagn 12 6 2010 808 817
-
(2010)
J Mol Diagn
, vol.12
, Issue.6
, pp. 808-817
-
-
Jiang, J.1
Wei, L.H.2
Li, Y.L.3
Wu, R.F.4
Xie, X.5
Feng, Y.J.6
-
27
-
-
0032170044
-
Telomerase activity exclusively in cervical carcinomas and a subset of cervical intraepithelial neoplasia grade III lesions: Strong association with elevated messenger RNA levels of its catalytic subunit and high-risk human papillomavirus DNA
-
P.J. Snijders, M. van Duin, J.M. Walboomers, R.D. Steenbergen, E.K. Risse, and T.J. Helmerhorst Telomerase activity exclusively in cervical carcinomas and a subset of cervical intraepithelial neoplasia grade III lesions: strong association with elevated messenger RNA levels of its catalytic subunit and high-risk human papillomavirus DNA Cancer Res 58 17 1998 3812 3818
-
(1998)
Cancer Res
, vol.58
, Issue.17
, pp. 3812-3818
-
-
Snijders, P.J.1
Van Duin, M.2
Walboomers, J.M.3
Steenbergen, R.D.4
Risse, E.K.5
Helmerhorst, T.J.6
-
28
-
-
77953200263
-
HTERT promoter activity and CpG methylation in HPV-induced carcinogenesis
-
J. de Wilde, J.M. Kooter, R.M. Overmeer, D. Claassen-Kramer, C.J. Meijer, and P.J. Snijders hTERT promoter activity and CpG methylation in HPV-induced carcinogenesis BMC Cancer 10 2010 271 284
-
(2010)
BMC Cancer
, vol.10
, pp. 271-284
-
-
De Wilde, J.1
Kooter, J.M.2
Overmeer, R.M.3
Claassen-Kramer, D.4
Meijer, C.J.5
Snijders, P.J.6
-
29
-
-
0027358723
-
The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53
-
M. Scheffner, J.M. Huibregtse, R.D. Vierstra, and P.M. Howley The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53 Cell 75 3 1993 495 505
-
(1993)
Cell
, vol.75
, Issue.3
, pp. 495-505
-
-
Scheffner, M.1
Huibregtse, J.M.2
Vierstra, R.D.3
Howley, P.M.4
-
30
-
-
7244253057
-
Role of the histone acetyl transferase Tip60 in the p53 pathway
-
G. Legube, L.K. Linares, S. Tyteca, C. Caron, M. Scheffner, and M. Chevillard-Briet Role of the histone acetyl transferase Tip60 in the p53 pathway J Biol Chem 279 43 2004 44825 44833
-
(2004)
J Biol Chem
, vol.279
, Issue.43
, pp. 44825-44833
-
-
Legube, G.1
Linares, L.K.2
Tyteca, S.3
Caron, C.4
Scheffner, M.5
Chevillard-Briet, M.6
-
31
-
-
2642610318
-
Myc activates telomerase
-
J. Wang, L.Y. Xie, S. Allan, D. Beach, and G.J. Hannon Myc activates telomerase Genes Dev 12 12 1998 1769 1774
-
(1998)
Genes Dev
, vol.12
, Issue.12
, pp. 1769-1774
-
-
Wang, J.1
Xie, L.Y.2
Allan, S.3
Beach, D.4
Hannon, G.J.5
-
32
-
-
0034142386
-
Spl cooperates with c-Myc to activate transcription of the human telomerase reverse transcriptase gene (hTERT)
-
S. Kyo, M. Takakura, T. Taira, T. Kanaya, H. Itoh, and M. Yutsudo Spl cooperates with c-Myc to activate transcription of the human telomerase reverse transcriptase gene (hTERT) Nucleic Acids Res 28 3 2000 669 677
-
(2000)
Nucleic Acids Res
, vol.28
, Issue.3
, pp. 669-677
-
-
Kyo, S.1
Takakura, M.2
Taira, T.3
Kanaya, T.4
Itoh, H.5
Yutsudo, M.6
-
33
-
-
0035957406
-
Switch from Myc/Max to Mad1/Max binding and decrease in histone acetylation at the telomerase reverse transcriptase promoter during differentiation of HL60 cells
-
D. Xu, N. Popov, M. Hou, Q. Wang, M. Björkholm, and A. Gruber Switch from Myc/Max to Mad1/Max binding and decrease in histone acetylation at the telomerase reverse transcriptase promoter during differentiation of HL60 cells Proc Natl Acad Sci U S A 98 7 2001 3826 3831
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, Issue.7
, pp. 3826-3831
-
-
Xu, D.1
Popov, N.2
Hou, M.3
Wang, Q.4
Björkholm, M.5
Gruber, A.6
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