Murine dendritic cells transcriptional modulation upon Paracoccidioides brasiliensis infection

PLoS Neglected Tropical Diseases

Volumn 6, Issue 1, 2012, Pages

  Tavares, Aldo H ^a   Derengowski, Lorena S ^a   Ferreira, Karen S ^b   Silva, Simoneide S ^a   Macedo, Cláudia ^c   Bocca, Anamélia L ^a   Passos, Geraldo A ^c   Almeida, Sandro R ^c   Silva Pereira, Ildinete ^a  

^a UNIVERSITY OF BRASILIA   (Brazil)

^b FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^c UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

CUTANEOUS T CELL ATTRACTING CHEMOKINE; DECTIN 1; GAMMA INTERFERON INDUCIBLE PROTEIN 10; INTERLEUKIN 10; INTERLEUKIN 12; MACROPHAGE DERIVED CHEMOKINE; MANNOSE RECEPTOR; PATTERN RECOGNITION RECEPTOR; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA; PROTEOME;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; DENDRITIC CELL; DNA TRANSCRIPTION; EFFECTOR CELL; GENE EXPRESSION; HOST PARASITE INTERACTION; IMMUNE RESPONSE; IMMUNE RESPONSE GENE; MALE; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PARACOCCIDIOIDES BRASILIENSIS; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SOUTH AMERICAN BLASTOMYCOSIS; UNINDEXED SEQUENCE; ANIMAL; BAGG ALBINO MOUSE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; IMMUNOLOGY; PARACOCCIDIOIDES; PARASITOLOGY; PHYSIOLOGICAL STRESS;

ANIMALS; DENDRITIC CELLS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; MALE; MICE; MICE, INBRED BALB C; MICROARRAY ANALYSIS; PARACOCCIDIOIDES; PROTEOME; REAL-TIME POLYMERASE CHAIN REACTION; STRESS, PHYSIOLOGICAL;

EID: 84856585774     PISSN: 19352727     EISSN: 19352735     Source Type: Journal    
DOI: 10.1371/journal.pntd.0001459     Document Type: Article

References (51)

1. Prado M, Silva MB, Laurenti R, Travassos LR, Taborda CP, (2009) Mortality due to systemic mycoses as a primary cause of death or in association with AIDS in Brazil: a review from 1996 to 2006. Mem Inst Oswaldo Cruz 104: 513-521.
2. Restrepo A, McEwen JG, Castañeda E, (2001) The habitat of Paracoccidioides brasiliensis: how far from solving the riddle? Med Mycol 39: 233-241.
3. Borges-Walmsley MI, Chen D, Shu X, Walmsley AR, (2002) The pathobiology of Paracoccidioides brasiliensis. Trends Microbiol 10: 80-87.
4. Buentke E, Scheynius A, (2003) Dendritic cells and fungi. APMIS 111: 789-96.
5. Calich VL, Kashino SS, (1998) Cytokines produced by susceptible and resistant mice in the course of Paracoccidioides brasiliensis infection. Braz J Med Biol Res 31: 615-623.
6. Calich VL, da Costa TA, Felonato M, Arruda C, Bernardino S, et al. (2008) Innate immunity to Paracoccidioides brasiliensis infection. Mycopathologia 165: 223-236.
7. Romano CC, Mendes-Giannini MJ, Duarte AJ, Benard G, (2002) IL-12 and neutralization of endogenous IL-10 revert the in vitro antigen-specific cellular immunosuppression of paracoccidioidomycosis patients. Cytokine 18: 149-157.
8. Silvana Dos Santos S, Ferreira KS, Almeida SR, (2011) Paracoccidioides brasilinsis-Induced Migration of Dendritic Cells and Subsequent T-Cell Activation in the Lung-Draining Lymph Nodes. PLoS One 6 (5).
9. Brown GD, (2011) Innate antifungal immunity: the key role of phagocytes. Annu Rev Immunol 29: 1-21.
10. Romani L, (2011) Immunity to fungal infections. Nat Rev Immunol 11: 275-288.
11. Claudia M, Bacci A, Silvia B, Gaziano R, Spreca A, et al. (2002) The interaction of fungi with dendritic cells: implications for Th immunity and vaccination. Curr Mol Med 2: 507-524.
12. Huang Q, Liu D, Majewski P, Schulte LC, Korn JM, et al. (2001) The plasticity of dendritic cell responses to pathogens and their components. Science 294: 870-875.
13. Calich VL, Singer-Vermes LM, Siqueira AM, Burger E, (1985) Susceptibility and resistance of inbred mice to Paracoccidioides brasiliensis. Br J Exp Pathol 66: 585-594.
14. Inaba K, Inaba M, Romani N, Aya H, Deguchi M, et al. (1992) Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor. J Exp Med 176: 1693-1702.
15. Hegde P, Qi R, Abernathy K, Gay C, Dharap S, et al. (2000) A concise guide to cDNA microarray analysis. Biotechniques 29: 548-550.
16. Tusher VG, Tibshirani R, Chu G, (2001) Significance analysis of microarrays applied to the ionizing radiation response. Proc Natl Acad Sci U S A 98: 5116-21.
17. Livak KJ, Schmittgen TD, (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 25: 402-408.
18. Ferreira KS, Lopes JD, Almeida SR, (2004) Down-regulation of dendritic cell activation induced by Paracoccidioides brasiliensis. Immunol Lett 94: 107-114.
19. Luo BH, Carman CV, Springer TA, (2007) Structural basis of integrin regulation and signaling. Annu Rev Immunol 25: 619-647.
20. Mazzone A, Ricevuti G, (1995) Leukocyte CD11/CD18 integrins: biological and clinical relevance. Haematologica 80: 161-175.
21. Degrandi D, Hoffmann R, Beuter-Gunia C, Pfeffer K, (2009) The proinflammatory cytokine-induced IRG1 protein associates with mitochondria. J Interferon Cytokine Res 29: 55-67.
22. Niedick I, Froese N, Oumard A, Mueller PP, Nourbakhsh M, et al. (2004) Nucleolar localization and mobility analysis of the NF-kappaB repressing factor NRF. J Cell Sci 117: 3447-3458.
23. Vautier S, Sousa Mda G, Brown GD, (2010) C-type lectins, fungi and Th17 responses. Cytokine Growth Factor Rev 21: 405-412.
24. Lupo P, Chang YC, Kelsall BL, Farber JM, Pietrella D, et al. (2008) The presence of capsule in Cryptococcus neoformans influences the gene expression profile in dendritic cells during interaction with the fungus. Infect Immun 76: 1581-1589.
25. Almeida SR, Lopes JD, (2001) The low efficiency of dendritic cells and macrophages from mice susceptible to Paracoccidioides brasiliensis in inducing a Th1 response. Braz J Med Biol Res 34: 529-537.
26. Ferreira KS, Lopes JD, Almeida SR, (2003) Regulation of T helper cell differentiation in vivo by GP43 from Paracoccidioides brasiliensis provided by different antigen-presenting cells. Scand J Immunol 58: 290-297.
27. Livonesi MC, Souto JT, Campanelli AP, Maffei CM, Martinez R, et al. (2008) Deficiency of IL-12p40 subunit determines severe paracoccidioidomycosis in mice. Med Mycol 46: 637-646.
28. Moraes-Vasconcelos D, Grumach AS, Yamaguti A, Andrade ME, Fieschi C, et al. (2005) Paracoccidioides brasiliensis disseminated disease in a patient with inherited deficiency in the beta1 subunit of the interleukin (IL)-12/IL-23 receptor. Clin Infect Dis 41: 31-37.
29. Torri A, Beretta O, Ranghetti A, Granucci F, Ricciardi-Castagnoli P, et al. (2010) Gene expression profiles identify inflammatory signatures in dendritic cells. PLoS One 5 (2).
30. Bonizzi G, Karin M, (2004) The two NF-kappaB activation pathways and their role in innate and adaptive immunity. Trends Immunol 25: 280-288.
31. Roach DR, Bean AG, Demangel C, France MP, Briscoe H, et al. (2002) TNF regulates chemokine induction essential for cell recruitment, granuloma formation, and clearance of mycobacterial infection. J Immunol 168: 4620-4627.
32. Souto JT, Figueiredo F, Furlanetto A, Pfeffer K, Rossi MA, et al. (2000) Interferon-gamma and tumor necrosis factor-alpha determine resistance to Paracoccidioides brasiliensis infection in mice. Am J Pathol 156: 1811-1820.
33. Herring AC, Falkowski NR, Chen GH, McDonald RA, Toews GB, et al. (2005) Transient neutralization of tumor necrosis factor alpha can produce a chronic fungal infection in an immunocompetent host: potential role of immature dendritic cells. Infect Immun 73: 39-49.
34. Traynor TR, Huffnagle GB, (2001) Role of chemokines in fungal infections. Med Mycol 39: 41-50.
35. Vulcano M, Albanesi C, Stoppacciaro A, Bagnati R, D'Amico G, et al. (2001) Dendritic cells as a major source of macrophage-derived chemokine/CCL22 in vitro and in vivo. Eur J Immunol 31: 812-22.
36. Silva SS, Tavares AH, Passos-Silva DG, Fachin AL, Teixeira SM, et al. (2008) Transcriptional response of murine macrophages upon infection with opsonized Paracoccidioides brasiliensis yeast cells. Microbes Infect 10: 12-20.
37. Matsukawa A, Hogaboam CM, Lukacs NW, Lincoln PM, Evanoff HL, et al. (2000) Pivotal role of the CC chemokine, macrophage-derived chemokine, in the innate immune response. J Immunol 164: 5362-5368.
38. Romagnani P, Maggi L, Mazzinghi B, Cosmi L, Lasagni L, et al. (2005) CXCR3-mediated opposite effects of CXCL10 and CXCL4 on TH1 or TH2 cytokine production. J Allergy Clin Immunol 116: 1372-1379.
39. Mezger M, Steffens M, Beyer M, Manger C, Eberle J, et al. (2008) Polymorphisms in the chemokine (C-X-C motif) ligand 10 are associated with invasive aspergillosis after allogeneic stem-cell transplantation and influence CXCL10 expression in monocyte-derived dendritic cells. Blood 111: 534-536.
40. Willment JA, Brown GD, (2008) C-type lectin receptors in antifungal immunity. Trends Microbiol 16: 27-32.
41. van de Veerdonk FL, Kullberg BJ, van der Meer JW, Gow NA, Netea MG, (2008) Host-microbe interactions: innate pattern recognition of fungal pathogens. Curr Opin Microbiol 11: 305-312.
42. Cunha C, Romani L, Carvalho A, (2010) Cracking the Toll-like receptor code in fungal infections. Expert Rev Anti Infect Ther 8: 1121-1137.
43. González A, Yáñez A, Gozalbo D, Gil ML, (2008) MyD88 is dispensable for resistance to Paracoccidioides brasiliensis in a murine model of blood-borne disseminated infection. FEMS Immunol Med Microbiol 54: 365-374.
44. Loures FV, Pina A, Felonato M, Feriotti C, de Araújo EF, et al. (2011) MyD88 signaling is required for efficient innate and adaptive immune responses to Paracoccidioides brasiliensis infection. Infect Immun 79: 2470-2480.
45. Burns K, Clatworthy J, Martin L, Martinon F, Plumpton C, et al. (2000) Tollip, a new component of the IL-1RI pathway, links IRAK to the IL-1 receptor. Nat Cell Biol 2: 346-351.
46. Zangh G, Gosh S, (2002) Negative regulation of toll-like receptor-mediated signaling by Tollip. J Biol Chem 277: 7059-7065.
47. Divanovic S, Trompette A, Atabani SF, Madan R, Golenbock DT, et al. (2005) Inhibition of TLR-4/MD-2 signaling by RP105/MD-1. J Endotoxin Res 11: 363-368.
48. Loures FV, Pina A, Felonato M, Calich VL, (2009) TLR2 is a negative regulator of Th17 cells and tissue pathology in a pulmonary model of fungal infection. J Immunol 183: 1279-1290.
49. Loures FV, Pina A, Felonato M, Araújo EF, Leite KR, et al. (2010) Toll-like receptor 4 signaling leads to severe fungal infection associated with enhanced proinflammatory immunity and impaired expansion of regulatory T cells. Infect Immun 78: 1078-1088.
50. Nakamura K, Miyagi K, Koguchi Y, Kinjo Y, Uezu K, et al. (2006) Limited contribution of Toll-like receptor 2 and 4 to the host response to a fungal infectious pathogen, Cryptococcus neoformans. FEMS Immunol Med Microbiol 47: 148-154.
51. Ferreira KS, Bastos KR, Russo M, Almeida SR, (2007) Interaction between Paracoccidioides brasiliensis and pulmonary dendritic cells induces interleukin-10 production and toll-like receptor-2 expression: possible mechanisms of susceptibility. J Infect Dis 196: 1108-1115.