The chronic effects of fish oil with exercise on postprandial lipaemia and chylomicron homeostasis in insulin resistant viscerally obese men

Nutrition and Metabolism

Volumn 9, Issue , 2012, Pages

  Slivkoff Clark, Karin M ^a   James, Anthony P ^a   Mamo, John C L ^a  

^a CURTIN UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN B48; CHYLOMICRON; DOCOSAHEXAENOIC ACID; GLUCOSE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; ICOSAPENTAENOIC ACID; INSULIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; PLACEBO;

ADULT; AGED; ARTICLE; CHOLESTEROL BLOOD LEVEL; CLINICAL ARTICLE; CONTROLLED STUDY; EXERCISE; GLUCOSE BLOOD LEVEL; HUMAN; HUMAN TISSUE; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; LIPID BLOOD LEVEL; LIPID METABOLISM; MALE; METABOLIC SYNDROME X; OBESITY; RANDOMIZED CONTROLLED TRIAL; WALKING;

EID: 84856568709     PISSN: None     EISSN: 17437075     Source Type: Journal    
DOI: 10.1186/1743-7075-9-922314022     Document Type: Article

References (61)

1. WHO: Global Strategy on Diet, Physical Activity and Health. Geneva, WHO; 2004.
2. WHO: Global status report on noncommunicable diseases 2010: Description of the global burden of NCDs, their risk factors and determinants. Geneva, World Health Organization; 2010, 22.
3. Redgrave TG: Chylomicrons in disease-future challenges Invited keynote address. Atheroscler Suppl 2008, 9:3-6.
4. Nakano T, Nakajima K, Niimi M, Fujita MQ, Nakajima Y, Takeichi S, Kinoshita M, Matsushima T, Teramoto T, Tanaka A: Detection of apolipoproteins B-48 and B-100 carrying particles in lipoprotein fractions extracted from human aortic atherosclerotic plaques in sudden cardiac death cases. Clinica Chimica Acta 2008, 390:38-43.
5. Karpe F, Bickerton AS, Hodson L, Fielding BA, Tan GD, Frayn KN: Removal of triacylglycerols from chylomicrons and VLDL by capillary beds: the basis of lipoprotein remnant formation. Biochemical Society Transactions 2007, 35:472-476. (Pubitemid 46975055)
6. Pan X, Hussain MM: Gut triglyceride production. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 2011.
7. Chan DC, Watts GF, Barrett PH, Mamo JC, Redgrave TG: Markers of triglyceride-rich lipoprotein remnant metabolism in visceral obesity. Clin Chem 2002, 48:278-283. (Pubitemid 34107264)
8. Otokozawa S, Ai M, Diffenderfer MR, Sarnak MJ, Schaefer EJ: Fasting and postprandial apolipoprotein B-48 levels in healthy, obese, and hyperlipidaemic subjects. Metabolism 2009, 58:1536-1542.
9. Batista MC, Welty FK, Diffenderfer MR, Sarnak MJ, Schaefer EJ, Lamona-Fava S, Dolnikowski GG, Brousseau ME, Marsh JB: Apolipoprotein A-I, B-100, and B-48 metabolism in subjects with chronic kidney disease, obesity and the metabolic syndrome. Metabolism 2004, 53:1255-1261. (Pubitemid 39222084)
10. Allister EM, James AP, Watts GF, Barrett PH, Mamo JC: Effect of an acute hyperinsulinaemic clamp on post-prandial lipaemia in subjects with insulin resistance. Eur J Clin Invest 2006, 36:489-496. (Pubitemid 43876129)
11. James AP, Watts GF, Mamo JC: The effect of metformin and rosiglitazone on postprandial lipid metabolism in obese insulin-resistant subjects. Diabetes Obes Metab 2005, 7:381-389. (Pubitemid 40916580)
12. James AP, Watts GF, Barrett PH, Smith D, Pal S, Chan DC, Mamo JC: Effect of weight loss on postprandial lipemia and low-density lipoprotein receptor binding in overweight men. Metabolism 2003, 52:136-141. (Pubitemid 36388832)
13. Valdivielso P, Rioja J, Garcia-Arias C, Sanchez-Chaparro M, Gonzalez-Santos P: Omega 3 fatty acids induce a marked reduction of apolipoprotein B48 when added to fluvastatin in patients with type 2 diabetes and mixed hyperlipidemia: a preliminary report. Cardiovascular Diabetology 2009, 8:1.
14. Chan DC, Watts GF, Mori TA, Barrett PH, Beilin LJ, Redgrave TG: Factorial study of the effects of atorvastatin and fish oil on dyslipidaemia in visceral obesity. Eur J Clin Invest 2002, 32:429-436. (Pubitemid 36223433)
15. Harris WS, Bulchandani D: Why do omega-3 fatty acids lower serum triglycerides? Curr Opin Lipidol 2006, 17:387-393. (Pubitemid 44079475)
16. Jackson KG, Robertson MD, Fielding BA, Frayn KN, Williams CM: Measurement of apolipoprotein B-48 in the Svedberg flotation rate (S(f)) > 400, S(f) 60-400 and S(f) 20-60 lipoprotein fractions reveals novel findings with respect to the effects of dietary fatty acids on triacylglycerol-rich lipoproteins in postmenopausal women. Clin Sci (Lond) 2002, 103:227-237. (Pubitemid 35007214)
17. Cao J, Schwichtenberg KA, Hanson NQ, Tsai MY: Incorporation and Clearance of Omega-3 Fatty Acids in Erythrocyte Membranes and Plasma Phospholipids. Clinical Chemistry 2006, 52:2265-2272. (Pubitemid 44925001)
18. Williams CM, Bateman PA, Jackson KG, Yaqoob P: Dietary fatty acids and chylomicron synthesis and secretion. Biochem Soc Trans 2004, 32:55-58. (Pubitemid 38283013)
19. Lovegrove JA, Lovegrove SS, Lesauvage SV, Brady LM, Saini N, Minihane AM, Williams CM: Moderate fish-oil supplementation reverses low-platelet, long-chain n-3 polyunsaturated fatty acid status and reduces plasma triacylglycerol concentrations in British Indo-Asians. The American Journal of Clinical Nutrition 2004, 79:974-982. (Pubitemid 41095948)
20. Black IL, Roche HM, Tully AM, Gibney MJ: Acute-on-chronic effects of fatty acids on intestinal triacylglycerol-rich lipoprotein metabolism. Br J Nutr 2002, 88:661-669. (Pubitemid 36082895)
21. Levy E, Spahis S, Ziv E, Marette A, Elchebly M, Lambert M, Delvin E: Overproduction of intestinal lipoprotein containing apolipoprotein B48 in Psammomys obesis: impact of dietary n-3 fatty acids. Diabetologia 2007, 49:1937-1945. (Pubitemid 44025049)
22. Lambert MS, Avella MA, Berhane Y, Shervill E, Botham KM: The fatty acid composition of chylomicron remnants influences their binding and internalization by isolated hepatocytes. Eur J Biochem 2001, 268:3983-3992. (Pubitemid 32868611)
23. Chan DC, Watts GF, Mori TA, Barrett PH, Redgrave TG, Beilin LJ: Randomized controlled trial of the effect of n-3 fatty acid supplementation on the metabolism of apolipoprotein B-100 and chylomicron remnants in men with visceral obesity. Am J Clin Nutr 2003, 77:300-307. (Pubitemid 36133369)
24. Gill JM, Al-Mamari A, Ferrell WR, Cleland SJ, Sattar N, Packard CJ, Petrie JR, Caslake MJ: Effects of a moderate exercise session on postprandial lipoproteins, apolipoproteins and lipoprotein remnants in middle-aged men. Atherosclerosis 2006, 185:87-96. (Pubitemid 43117554)
25. Gavin C, Sigal RJ, Cousins M, Menard ML, Atkinson M, Khandwala F, Kenny GP, Proctor S, Ooi TC: Resistance exercise but not aerobic exercise lowers remnant-like lipoprotein particle cholesterol in type 2 diabetes: a randomized controlled trial. Atherosclerosis 2010, 213:552-557.
26. Kelley GA, Kelley KS, Tran ZV: Aerobic exercise, lipids and lipoproteins in overweight and obese adults: a meta-analysis of randomized controlled trials. Int J Obes 2005, 29:881-893. (Pubitemid 41076227)
27. National Institutes of Health: Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) final report. Circulation 2002, 106:3143-3421.
28. Metcalfe L, Schmitz A, Pelka J: Rapid preparation of fatty acid esters from lipids for gas chromatographic analysis. Analytical Chemistry 1966, 38:515-515.
29. Delarue J, Labarthe F, Cohen R: Fish-oil supplementation reduces stimulation of plasma glucose fluxes during exercise in untrained males. Br J Nutr 2003, 90:777-786. (Pubitemid 37270760)
30. American College of Sports Medicine: ACSM'S Resource Manual for Guidelines for Exercise Testing and Prescription. Philadelphia, Lippincott Williams & Wilkins;, 4 2001.
31. Australian Bureau of Statistics: Nutrient intakes and physical measurements. Catalogue number 4805.0. National Nutrition Survey Canberra, Australian Bureau of Statistics; 1998, Catalogue number 4805.4800.
32. Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC: Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 1985, 28:412-419. (Pubitemid 15018832)
33. Wallace TM, Levy JC, Matthews DR: Use and abuse of HOMA modeling. Diabetes Care 2004, 27:1487-1495. (Pubitemid 38680001)
34. Matthews JN, Altman DG, Campbell MJ, Royston P: Analysis of serial measurements in medical research. BMJ 1990, 300:230-235. (Pubitemid 20045528)
35. Gill JM, Herd SL, Vora V, Hardman AE: Effects of a brisk walk on lipoprotein lipase activity and plasma triglyceride concentrations in the fasted and postprandial states. Eur J Appl Physiol 2003, 89:184-190. (Pubitemid 36747975)
36. Qi K, Fan C, Jiang J, Zhu H, Jiao H, Meng Q, Deckelbaum RJ: Omega-3 fatty acid containing diets decrease plasma triglyceride concentrations in mice by reducing endogenous triglyceride synthesis and enhancing the blood clearance of triglyceride-rich particles. Clinical Nutrition 2008, 27:424-430.
37. Ziogas GG, Thomas TR, Harris WS: Exercise training, postprandial hypertriglyceridemia, and LDL subfraction distribution. Med Sci Sports Exerc 1997, 29:986-991. (Pubitemid 27349763)
38. Seip RL, Semenkovich CF: Skeletal muscle lipoprotein lipase: molecular regulation and physiological effects in relation to exercise. Exerc Sport Sci Rev 1998, 26:191-218. (Pubitemid 128461557)
39. Khan S, Minihane AM, Talmud PJ, Wright JW, Murphy MC, Williams CM, Griffin BA: Dietary long-chain n-3 PUFAs increase LPL gene expression in adipose tissue of subjects with an atherogenic lipoprotein phenotype. J Lipid Res 2002, 43:979-985. (Pubitemid 34602621)
40. Lu G, Windsor SL, Harris WS: Omega-3 fatty acids alter lipoprotein subfraction distributions and the in vitro conversion of very low density lipoproteins to low density lipoproteins. J Nutr Biochem 1999, 10:151-158. (Pubitemid 29101639)
41. Nestel PJ: Fish oil and cardiovascular disease: lipids and arterial function. Am J Clin Nutr 2000, 71:228S-231S.
42. Thomas TR, Smith BK, Donahue OM, Altena TS, James-Kracke M, Sun GY: Effects of omega-3 fatty acid supplementation and exercise on low-density lipoprotein and high-density lipoprotein subfractions. Metabolism 2004, 53:749-754. (Pubitemid 38880906)
43. Mori TA, Burke V, Puddey IB, Watts GF, O'Neal DN, Best JD, Beilin LJ: Purified eicosapentaenoic and docosahexaenoic acids have differential effects on serum lipids and lipoproteins, LDL particle size, glucose, and insulin in mildly hyperlipidemic men. Am J Clin Nutr 2000, 71:1085-1094. (Pubitemid 30230554)
44. Woodman RJ, Mori TA, Burke V, Puddey IB, Watts GF, Beilin LJ: Effects of purified eicosapentaenoic and docosahexaenoic acids on glycemic control, blood pressure, and serum lipids in type 2 diabetic patients with treated hypertension. Am J Clin Nutr 2002, 76:1007-1015. (Pubitemid 35244671)
45. Mori TA, Bao DQ, Burke V, Puddey IB, Watts GF, Beilin LJ: Dietary fish as a major component of a weight-loss diet: effect on serum lipids, glucose, and insulin metabolism in overweight hypertensive subjects. Am J Clin Nutr 1999, 70:817-825. (Pubitemid 29512906)
46. Dunstan DW, Mori TA, Puddey IB, Beilin LJ, Burke V, Morton AR, Stanton KG: The independent and combined effects of aerobic exercise and dietary fish intake on serum lipids and glycemic control in NIDDM. A randomized controlled study. Diabetes Care 1997, 20:913-921. (Pubitemid 27224938)
47. Wei C, Penumetcha M, Santanam N, Liu Y-G, Garelnabi M, Parthasarathy S: Exercise might favor reverse cholesterol transport and lipoprotein clearance: Potential mechanism for its anti-atherosclerotic effects. Biochimica et Biophysica Acta (BBA) - General Subjects 2005, 1723:124-127.
48. Patalay M, Lofgren IE, Freake HC, Koo SI, Fernandez ML: The lowering of plasma lipids following a weight reduction program is related to increased expression of the LDL receptor and lipoprotein lipase. J Nutr 2005, 135:735-739. (Pubitemid 40464096)
49. Yan Y, Zhang Y, Yang X, Hua Q: [Effects of aerobic exercise on regulation of activities of hepatic low density lipoprotein receptor in hypercholesterolemic rats]. Zhongguo Ying Yong Sheng Li Xue Za Zhi 1997, 13:18-20.
50. Botham KM, Maldonado EN, Chico Y, Zheng X, Avella M, Ochoa B: The influence of chylomicron remnants on cholesteryl ester metabolism in cultured rat hepatocytes: comparison of the effects of particles enriched in n-3 or n-6 polyunsaturated fatty acids. Biochim Biophys Acta 2001, 1534:96-109. (Pubitemid 34084966)
51. Yu-Poth S, Yin D, Kris-Etherton PM, Zhao G, Etherton TD: Long-Chain Polyunsaturated Fatty Acids Upregulate LDL Receptor Protein Expression in Fibroblasts and HepG2 Cells. J Nutr 2005, 135:2541-2545. (Pubitemid 43156593)
52. Zheng X, Rivabene R, Cavallari C, Napolitano M, Avella M, Bravo E, Botham KM: The effects of chylomicron remnants enriched in n-3 or n-6 polyunsaturated fatty acids on the transcription of genes regulating their uptake and metabolism by the liver: influence of cellular oxidative state. Free Radical Biology and Medicine 2002, 32:1123-1131. (Pubitemid 34603350)
53. Lu J, Borthwick F, Hassanali Z, Wang Y, Mangat R, Ruth M, Shi D, Jaeschke A, Russell JC, Field CJ, Proctor SD, Vine DF: Chronic dietary n-3 PUFA intervention improves dyslipidaemia and subsequent cardiovascular complications in the JCR:LA-cp rat model of the metabolic syndrome. British Journal of Nutrition 2011, 105:1572-1582.
54. Klop B, Proctor SD, Mamo JC, Botham KM, Castro Cabezas M: Understanding postprandial inflammation and its relationship to lifestyle behaviour and metabolic diseases. International journal of vascular medicine 2012, 2012:947417.
55. Woodman RJ, Chew GT, Watts GF: Mechanisms, significance and treatment of vascular dysfunction in type 2 diabetes mellitus: focus on lipid-regulating therapy. Drugs 2005, 65:31-74. (Pubitemid 40143801)
56. Elosua R, Molina L, Fito M, Arquer A, Sanchez-Quesada JL, Covas MI, Ordonez-Llanos J, Marrugat J: Response of oxidative stress biomarkers to a 16-week aerobic physical activity program, and to acute physical activity, in healthy young men and women. Atherosclerosis 2003, 167:327-334. (Pubitemid 36773532)
57. Meilhac O, Ramachandran S, Chiang K, Santanam N, Parthasarathy S: Role of Arterial Wall Antioxidant Defense in Beneficial Effects of Exercise on Atherosclerosis in Mice. Arterioscler Thromb Vasc Biol 2001, 21:1681-1688. (Pubitemid 34215591)
58. Ma DWL, Seo J, Switzer KC, Fan Y-Y, McMurray DN, Lupton JR, Chapkin RS: n-3 PUFA and membrane microdomains: a new frontier in bioactive lipid research. The Journal of Nutritional Biochemistry 2004, 15:700-706. (Pubitemid 39611369)
59. Mori TA, Woodman RJ, Burke V, Puddey IB, Croft KD, Beilin LJ: Effect of eicosapentaenoic acid and docosahexaenoic acid on oxidative stress and inflammatory markers in treated-hypertensive type 2 diabetic subjects. Free Radical Biology and Medicine 2003, 35:772-781. (Pubitemid 37329480)
60. Napolitano M, Bravo E, Avella M, Chico Y, Ochoa B, Botham KM, Rivabene R: The fatty acid composition of chylomicron remnants influences their propensity to oxidate. Nutrition, Metabolism and Cardiovascular Diseases 2004, 14:241-247. (Pubitemid 39611865)
61. Tartibian B, Hajizadeh Maleki B, Kanaley J, Sadeghi K: Long-term aerobic exercise and omega-3 supplementation modulate osteoporosis through inflammatory mechanisms in post-menopausal women: a randomized, repeated measures study. Nutrition and Metabolism 2011, 8:71.