Dietary long-chain n-3 PUFAs increase LPL gene expression in adipose tissue of subjects with an atherogenic lipoprotein phenotype

Journal of Lipid Research

Volumn 43, Issue 6, 2002, Pages 979-985

  Khan, Syrah ^a   Minihane, Anne Marie ^b   Talmud, Philippa J ^c   Wright, John W ^a   Murphy, Margaret C ^a   Williams, Christine M ^b   Griffin, Bruce A ^a  

^a UNIVERSITY OF SURREY   (United Kingdom)

^b UNIVERSITY OF READING   (United Kingdom)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Fish oil; Lipoprotein lipase gene; Polyunsaturated fatty acids

Indexed keywords

APOLIPOPROTEIN E; FISH OIL; LIPOPROTEIN; LIPOPROTEIN LIPASE; LONG CHAIN FATTY ACID; LOW DENSITY LIPOPROTEIN; MESSENGER RNA; POLYUNSATURATED FATTY ACID; FATTY ACID; LIPID; UNSATURATED FATTY ACID;

ADIPOSE TISSUE; ARTICLE; ATHEROGENESIS; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIET SUPPLEMENTATION; DOUBLE BLIND PROCEDURE; DRUG EFFECT; ENZYME ACTIVITY; FAT INTAKE; GENE EXPRESSION; GENETIC POLYMORPHISM; GENOTYPE; HUMAN; HUMAN TISSUE; LIPID BLOOD LEVEL; LIPID COMPOSITION; MALE; NORMAL HUMAN; PHENOTYPE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; THROMBOCYTE MEMBRANE; TRIACYLGLYCEROL BLOOD LEVEL; BLOOD; CELL MEMBRANE; CROSSOVER PROCEDURE; GENETICS; LIPID METABOLISM; METABOLISM; THROMBOCYTE;

ADIPOSE TISSUE; APOLIPOPROTEINS E; BLOOD PLATELETS; CELL MEMBRANE; CROSS-OVER STUDIES; DIETARY FATS; DOUBLE-BLIND METHOD; FATTY ACIDS; FATTY ACIDS, UNSATURATED; FISH OILS; HUMAN; LIPIDS; LIPOPROTEIN LIPASE; LIPOPROTEINS; RNA, MESSENGER; SUPPORT, NON-U.S. GOV'T; HUMANS; LIPID METABOLISM;

EID: 0035988357     PISSN: 00222275     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (38)

1. Atherogenic lipoprotein phenotype. A proposed genetic marker for coronary heart disease
2. Role of plasma triglyceride in the regulation of plasma low density lipoprotein (LDL) subfractions: Relative contribution of small, dense LDL to coronary heart disease risk
3. Low density lipoprotein subclass patterns and risk of myocardial infarction
4. Lipoprotein heterogeneity and apolipoprotein B metabolism
5. Regulation of gene expression by dietary fatty acids
6. Role of N-6 and N-3 fatty acds in the dietary treatment of metabolic disorders
7. Reduction of postprandial triglyceridemia in humans by dietaryn-3 fatty acids
8. Polyunsaturated fatty acids regulate lipogenic and peroxisomal gene expression by indepenent mechansisms
9. Influence of n-3 fatty acid suppleentation on the endogenous activities of plasma lipases
10. Integration of carbohydrate, fat and protein meabolism in the whole body
11. Site-specific regulation of gene expression by n-3 polyunsaturated fatty acids in rat white adipose tissues
12. Pre-translational regulaion of the expression of the lipoprotein lipase (EC 3.1.1.34) gene by dietary fatty acids in the rat
13. The quantitation of lipoprotein lipase mRNA in biopsies of human adiose tissue, using the polymerase chain reaction, and the effect of increased consumption of n-3 polyunsaturated fatty acids
14. Moderate intake of n-3 fatty acids for 2 months has no detrimental effect on glucose metabolism and could ameliorate the lipid proile of type 2 diabetic men
15. Dietary polyunsaturated fats of the omega-6 and omega-3 series reduce postprandial lipoprotein levels. Chronic and acute effects of fat saturation on postprandial lipoprotein meabolism
16. Postheprin lipoltyic activity and plasma lipoprotein response to w-3 polynsaturated fatty acids in patients with primary hypertriglyceriemia
17. ApoE polymorphism and fish oil supplementation in subjects with an atherogenic lipoprotein phenotype
18. Single-step method of RNA isolation by acid guaninium thiocyanate-phenol-choloroform exraction
19. Acute regulation of phosphatidylinositol-3-kinase, Rad, GLUT 4 and lipoprotein lipase mRNA levels in human muscle
20. A simple saltingut procedure for extracting DNA from human nucleated cells
21. A method for the rapid determination of hundreds of apoE genotypes, combining simplified, optimised protocols from sample acquisition to PCR and restriction digestion analysis by miroplate array diagonal gel electrophoresis (MADGE)
22. Relation of components of inulin resistance syndrome to coronary heart disease risk
23. Changes of lipolytic enzymes cluster with insulin resistance syndrome
24. Increased plasma cholesteryl estertransfer protein in obese subjects
25. Familial comined hyperlipidemia and abnormal lipoprotein lipase
26. Lipoprotein lipase activity is decreased in a large cohort of patients with coronary arery disease and is associated with changes in lipids and lipoproeins
27. Fish oils and plasma lipid and lipoprotein meabolism in humans: A critical review
28. Dietary fish oils inhibit early events in the assembly of very low density lipoproteins and target apo B for degradation within the rough endoplasmic reticuum of hamster hepatocytes
29. Effects of dietary fatty acid composition on postprandial inulin, GIP and lipoprotein lipase activity
30. Liporotein lipase activity and intra- muscular triglyceride stores afterlong-term high fat and high-carbohydrate diets in physically trained men
31. Exerise induced human lipoprotein lipase gene expression in skeletal muscle but not adipose tissue
32. A comarison between the effects of gemfibrozil and simvastatin on insuin sensitivity in patients with non-insulin-dependent diabetes melitus and hyperlipoproteinemia
33. Postprandial lipemia, Fenofibrate and cornary artery disease
34. The tissue-specific expression of lipoprotein liase: Implications for energy and lipoprotein metabolism
35. Lipoprotein lipase gene exression: Physiological regulators at the transcriptional and postranscriptional level
36. Fatty acids regulate the expression of lipoprotein lipase gene and activity in preadipose and adipose cells
37. Two different mechanisms areinvolved in nutritional regulation of lipoprotein lipase in guineaig adipose tissue
38. Regulation of the synthesis,processing and translocation of lipoprotein lipase