Dual endothelin receptor blockade with tezosentan markedly attenuates hypoxia-induced pulmonary vasoconstriction in a porcine model

Acta Physiologica

Volumn 204, Issue 3, 2012, Pages 419-434

  Hedelin, P ^a,b,c   Kylhammar, D ^a,b,c   Radegran G ^a,b,c  

^a LUND UNIVERSITY HOSPITAL   (Sweden)

^b LUND UNIVERSITY   (Sweden)

^c UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Hypoxic pulmonary vasoconstriction; Pulmonary hypertension; Pulmonary vascular tone

Indexed keywords

ENDOTHELIN RECEPTOR; TEZOSENTAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA PRESSURE; ARTICLE; ARTIFICIAL VENTILATION; ATTENUATION; CONTROLLED STUDY; FEMALE; HEART OUTPUT; HEART RATE; HEART RIGHT ATRIUM PRESSURE; HEART STROKE VOLUME; HYPOTHESIS; HYPOXIC LUNG VASOCONSTRICTION; LUNG ARTERY PRESSURE; LUNG VASCULAR RESISTANCE; NONHUMAN; OXYGEN CONSUMPTION; PRIORITY JOURNAL; PULMONARY ARTERY OCCLUSION PRESSURE; SWINE; SYSTEMIC VASCULAR RESISTANCE; TREATMENT DURATION; TREATMENT RESPONSE;

ANIMALS; ANOXIA; ANTIHYPERTENSIVE AGENTS; BLOOD PRESSURE; CARDIAC OUTPUT; DISEASE MODELS, ANIMAL; FEMALE; HEART RATE; HYPERTENSION, PULMONARY; INFUSIONS, INTRAVENOUS; PULMONARY ARTERY; PYRIDINES; RECEPTOR, ENDOTHELIN A; RECEPTOR, ENDOTHELIN B; SWINE; TETRAZOLES; TIME FACTORS; VASCULAR RESISTANCE; VASOCONSTRICTION; VASODILATOR AGENTS;

EID: 84856557478     PISSN: 17481708     EISSN: 17481716     Source Type: Journal    
DOI: 10.1111/j.1748-1716.2011.02339.x     Document Type: Article

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