Oleanolic acid exerts an osteoprotective effect in ovariectomy-induced osteoporotic rats and stimulates the osteoblastic differentiation of bone mesenchymal stem cells in vitro

Menopause

Volumn 19, Issue 2, 2012, Pages 225-233

  Bian, Qin ^a,b   Liu, Shu Fen ^a   Huang, Jian Hua ^b   Yang, Zhu ^a   Tang, De Zhi ^a   Zhou, Quan ^a   Ning, You ^b   Zhao, Yong Jian ^a   Lu, Sheng ^a   Shen, Zi Yin ^b   Wang, Yong Jun ^a  

^a SHANGHAI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^b FUDAN UNIVERSITY   (China)

Author keywords

Bone mesenchymal stem cell; Oleanolic acid; Osteoporosis; Ovariectomy; Stem cell microarray

Indexed keywords

ALKALINE PHOSPHATASE; BETA ACTIN; CADHERIN; HISTONE DEACETYLASE 1; JAGGED1; NOTCH RECEPTOR; OLEANOLIC ACID; OSTEOCALCIN; TRANSCRIPTION FACTOR RUNX2;

ALKALINE PHOSPHATASE BLOOD LEVEL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE MASS; CELL ACTIVITY; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFECT; FEMALE; GENE EXPRESSION; GENE FUNCTION; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; MESENCHYMAL STEM CELL; MICRO-COMPUTED TOMOGRAPHY; MICROARRAY ANALYSIS; MORPHOMETRICS; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OSTEOBLAST; OSTEOLYSIS; OSTEOPOROSIS; OVARIECTOMY; PROTEIN BLOOD LEVEL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TREATMENT DURATION; UPREGULATION;

ANIMALS; CELL DIFFERENTIATION; CELL PROLIFERATION; FEMALE; GENE EXPRESSION PROFILING; MESENCHYMAL STEM CELLS; OLEANOLIC ACID; OSTEOBLASTS; OSTEOPOROSIS; OVARIECTOMY; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, NOTCH; SIGNAL TRANSDUCTION;

EID: 84856516785     PISSN: 10723714     EISSN: 15300374     Source Type: Journal    
DOI: 10.1097/gme.0b013e3182272ef1     Document Type: Article

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