Analysis of change patterns of microcomputed tomography 3-dimensional bone parameters as a high-throughput tool to evaluate antiosteoporotic effects of agents at an early stage of ovariectomy-induced osteoporosis in mice

Investigative Radiology

Volumn 41, Issue 9, 2006, Pages 704-712

  Xiang, Anbo ^a   Kanematsu, Masahiro ^a   Mitamura, Mana ^a   Kikkawa, Hideo ^a   Asano, Satoshi ^a   Kinoshita, Mine ^a  

^a Development and Medical Affairs Division   (Japan)

Author keywords

Estrogen deficiency; Histomorphometry; Microcomputed tomography ( CT) 3D bone parameters; Mouse osteoporosis model; Osteoporosis treatment agents

Indexed keywords

DRUG VEHICLE; ESTRADIOL; PARATHYROID HORMONE[1-34]; RALOXIFENE; ROLIPRAM;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE TISSUE; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; DIAGNOSTIC VALUE; ESTROGEN DEFICIENCY; FEMALE; HIGH THROUGHPUT SCREENING; METAPHYSIS; MICRO-COMPUTED TOMOGRAPHY; MORPHOMETRICS; MOUSE; NONHUMAN; OSSIFICATION; OSTEOLYSIS; OSTEOPOROSIS; OVARIECTOMY; PRIORITY JOURNAL; STATISTICAL SIGNIFICANCE; THREE DIMENSIONAL IMAGING; TRABECULAR BONE;

EID: 33747056873     PISSN: 00209996     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.rli.0000236921.77810.56     Document Type: Article

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