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Volumn 418, Issue 1, 2012, Pages 22-26

Carnosic acid, a pro-electrophilic compound, inhibits LPS-induced activation of microglia

Author keywords

Carnosic acid; INOS; LPS; Microglia; Nrf2; Phase 2 enzyme

Indexed keywords

CARNOSIC ACID; CYTOKINE; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE;

EID: 84856496886     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2011.12.087     Document Type: Article
Times cited : (32)

References (28)
  • 4
    • 76349087133 scopus 로고    scopus 로고
    • Signaling actions of electrophiles: anti-inflammatory therapeutic candidates
    • Groeger A.L., Freeman B.A. Signaling actions of electrophiles: anti-inflammatory therapeutic candidates. Molecular Interventions 2010, 10:39-50.
    • (2010) Molecular Interventions , vol.10 , pp. 39-50
    • Groeger, A.L.1    Freeman, B.A.2
  • 5
    • 79953300057 scopus 로고    scopus 로고
    • Transcription factor Nrf2 suppresses LPS-induced hyperactivation of BV-2 microglial cells
    • Koh K., Kim J., Jang Y.J., Yoon K., Cha Y., Lee H.J., Kim J. Transcription factor Nrf2 suppresses LPS-induced hyperactivation of BV-2 microglial cells. Journal of Neuroimmunology 2011, 233:160-167.
    • (2011) Journal of Neuroimmunology , vol.233 , pp. 160-167
    • Koh, K.1    Kim, J.2    Jang, Y.J.3    Yoon, K.4    Cha, Y.5    Lee, H.J.6    Kim, J.7
  • 7
    • 1942455887 scopus 로고    scopus 로고
    • Molecular mechanism activating Nrf2-Keap1 pathway in regulation of adaptive response to electrophiles
    • Itoh K., Tong K.I., Yamamoto M. Molecular mechanism activating Nrf2-Keap1 pathway in regulation of adaptive response to electrophiles. Free Radical Biology and Medicine 2004, 36:1208-1213.
    • (2004) Free Radical Biology and Medicine , vol.36 , pp. 1208-1213
    • Itoh, K.1    Tong, K.I.2    Yamamoto, M.3
  • 8
    • 0034490852 scopus 로고    scopus 로고
    • Chemoprotection against cancer by induction of phase 2 enzymes
    • Talalay P. Chemoprotection against cancer by induction of phase 2 enzymes. BioFactors 2000, 12:5-11.
    • (2000) BioFactors , vol.12 , pp. 5-11
    • Talalay, P.1
  • 9
    • 33845648094 scopus 로고    scopus 로고
    • Redox regulation of neuronal survival by electrophilic compounds
    • Satoh T., Lipton S.A. Redox regulation of neuronal survival by electrophilic compounds. Trends in Neurosciences 2007, 30:38-45.
    • (2007) Trends in Neurosciences , vol.30 , pp. 38-45
    • Satoh, T.1    Lipton, S.A.2
  • 10
    • 38449111059 scopus 로고    scopus 로고
    • Carnosic acid, a catechol-type electrophilic compound, protects neurons both in vitro and in vivo through activation of the Keap1/Nrf2 pathway via S-alkylation of specific cysteines
    • Satoh T., Kosaka K., Itoh K., Kobayashi A., Yamamoto M., Shimojo Y., Kitajima C., Kamins J.Cui.J., Okamoto S., Shirasawa T., Lipton S.A. Carnosic acid, a catechol-type electrophilic compound, protects neurons both in vitro and in vivo through activation of the Keap1/Nrf2 pathway via S-alkylation of specific cysteines. Journal of Neurochemistry 2008, 104:1131-1161.
    • (2008) Journal of Neurochemistry , vol.104 , pp. 1131-1161
    • Satoh, T.1    Kosaka, K.2    Itoh, K.3    Kobayashi, A.4    Yamamoto, M.5    Shimojo, Y.6    Kitajima, C.7    Kamins, J.8    Okamoto, S.9    Shirasawa, T.10    Lipton, S.A.11
  • 11
    • 40849145272 scopus 로고    scopus 로고
    • Carnosic acid protects neuronal HT22 cells through activation of the antioxidant-responsive element in free carboxylic acid- and catechol hydroxyl moieties-dependent manners
    • Satoh T., Izumi M., Inukai Y., Tsutumi Y., Nakayama N., Kosaka K., Kitajima C., Itoh K., Yokoi T., Shirasawa T. Carnosic acid protects neuronal HT22 cells through activation of the antioxidant-responsive element in free carboxylic acid- and catechol hydroxyl moieties-dependent manners. Neuroscience Letters 2008, 434:260-265.
    • (2008) Neuroscience Letters , vol.434 , pp. 260-265
    • Satoh, T.1    Izumi, M.2    Inukai, Y.3    Tsutumi, Y.4    Nakayama, N.5    Kosaka, K.6    Kitajima, C.7    Itoh, K.8    Yokoi, T.9    Shirasawa, T.10
  • 12
    • 77952035101 scopus 로고    scopus 로고
    • Activated glutathione metabolism participates in protective effects of carnosic acid against oxidative stress in neuronal HT22 cells
    • Tamaki Y., Tabuchi T., Takahashi T., Kosaka K., Satoh T. Activated glutathione metabolism participates in protective effects of carnosic acid against oxidative stress in neuronal HT22 cells. Planta Medica 2010, 76:683-688.
    • (2010) Planta Medica , vol.76 , pp. 683-688
    • Tamaki, Y.1    Tabuchi, T.2    Takahashi, T.3    Kosaka, K.4    Satoh, T.5
  • 13
    • 64049103791 scopus 로고    scopus 로고
    • Carnosic acid and carnosol inhibit adipocyte differentiation in mouse 3T3-L1 cells through induction of phase 2 enzymes and activation of glutathione metabolism
    • Takahashi T., Tabuchi T., Tamaki Y., Kosaka K., Takikawa Y., Satoh T. Carnosic acid and carnosol inhibit adipocyte differentiation in mouse 3T3-L1 cells through induction of phase 2 enzymes and activation of glutathione metabolism. Biochemical and Biophysical Research Communications 2009, 382:549-554.
    • (2009) Biochemical and Biophysical Research Communications , vol.382 , pp. 549-554
    • Takahashi, T.1    Tabuchi, T.2    Tamaki, Y.3    Kosaka, K.4    Takikawa, Y.5    Satoh, T.6
  • 15
    • 0842304134 scopus 로고    scopus 로고
    • Nuclear factor E2-related factor 2-dependent antioxidant response element activation by tert-butylhydroquinone and sulforaphane occurring preferentially in astrocytes conditions neurons against oxidative insult
    • Kraft A.D., Johnson D.A., Johnson J.A. Nuclear factor E2-related factor 2-dependent antioxidant response element activation by tert-butylhydroquinone and sulforaphane occurring preferentially in astrocytes conditions neurons against oxidative insult. Journal of Neuroscience 2004, 24:1101-1112.
    • (2004) Journal of Neuroscience , vol.24 , pp. 1101-1112
    • Kraft, A.D.1    Johnson, D.A.2    Johnson, J.A.3
  • 16
    • 27644520207 scopus 로고    scopus 로고
    • 2+ influx and pore formation induced by the activation of P2X7 nucleotide receptors in mouse microglial cell line
    • 2+ influx and pore formation induced by the activation of P2X7 nucleotide receptors in mouse microglial cell line. Biochimica et Biophysica Acta 2005, 1726:177-186.
    • (2005) Biochimica et Biophysica Acta , vol.1726 , pp. 177-186
    • Takenouchi, T.1    Ogihara, K.2    Sato, M.3    Kitani, H.4
  • 18
    • 50949128076 scopus 로고    scopus 로고
    • Lysophospholipids and ATP mutually suppress maturation and release of IL-1 beta in mouse microglial cells using a Rho-dependent pathway
    • Takenouchi T., Iwamaru Y., Sugama S., Sato M., Hashimoto M., Kitani H H. Lysophospholipids and ATP mutually suppress maturation and release of IL-1 beta in mouse microglial cells using a Rho-dependent pathway. Journal of Immunology 2008, 180:7827-7839.
    • (2008) Journal of Immunology , vol.180 , pp. 7827-7839
    • Takenouchi, T.1    Iwamaru, Y.2    Sugama, S.3    Sato, M.4    Hashimoto, M.5    Kitani H, H.6
  • 19
    • 34250220190 scopus 로고    scopus 로고
    • Lysophosphatidylcholine potentiates Ca2+ influx, pore formation and p44/42 MAP kinase phosphorylation mediated by P2X7 receptor activation in mouse microglial cells
    • Takenouchi T., Sato M., Kitani H. Lysophosphatidylcholine potentiates Ca2+ influx, pore formation and p44/42 MAP kinase phosphorylation mediated by P2X7 receptor activation in mouse microglial cells. Journal of Neurochemistry 2007, 102:1518-1532.
    • (2007) Journal of Neurochemistry , vol.102 , pp. 1518-1532
    • Takenouchi, T.1    Sato, M.2    Kitani, H.3
  • 21
    • 0030978319 scopus 로고    scopus 로고
    • A highly water-soluble disulfonated tetrazolium salt as a chromogenic indicator for NADH as well as cell viability
    • Ishiyama M., Miyazono Y., Sasamoto K., Ohkura Y., Ueno K. A highly water-soluble disulfonated tetrazolium salt as a chromogenic indicator for NADH as well as cell viability. Talanta 1997, 44:1299-1305.
    • (1997) Talanta , vol.44 , pp. 1299-1305
    • Ishiyama, M.1    Miyazono, Y.2    Sasamoto, K.3    Ohkura, Y.4    Ueno, K.5
  • 22
    • 33645751448 scopus 로고    scopus 로고
    • Evaluation of total plasma nitric oxide concentrations in broilers infused intravenously with sodium nitrite, lipopolysaccharide, aminoguanidine, and sodium nitroprusside
    • Chapman M.E., Wideman R.F. Evaluation of total plasma nitric oxide concentrations in broilers infused intravenously with sodium nitrite, lipopolysaccharide, aminoguanidine, and sodium nitroprusside. Poultry Science 2006, 85:312-320.
    • (2006) Poultry Science , vol.85 , pp. 312-320
    • Chapman, M.E.1    Wideman, R.F.2
  • 24
    • 80755140582 scopus 로고    scopus 로고
    • Strongylophorine-8, a pro-electrophilic compound from the marine sponge Petrosia (Strongylophora) corticata, provides neuroprotection through Nrf2/ARE pathway
    • Sasaki S., Tozawa T., Van Wagoner R.M., Ireland C.M., Harper M.K., Satoh T. Strongylophorine-8, a pro-electrophilic compound from the marine sponge Petrosia (Strongylophora) corticata, provides neuroprotection through Nrf2/ARE pathway. Biochemical and Biophysical Research Communications 2011, 415:6-10.
    • (2011) Biochemical and Biophysical Research Communications , vol.415 , pp. 6-10
    • Sasaki, S.1    Tozawa, T.2    Van Wagoner, R.M.3    Ireland, C.M.4    Harper, M.K.5    Satoh, T.6
  • 27
    • 34648843243 scopus 로고    scopus 로고
    • Pathologically-activated therapeutics
    • Lipton S.A. Pathologically-activated therapeutics. Nature Reviews Neuroscience 2007, 8:803-808.
    • (2007) Nature Reviews Neuroscience , vol.8 , pp. 803-808
    • Lipton, S.A.1
  • 28
    • 75449091854 scopus 로고    scopus 로고
    • Activation of the NRF2 signaling pathway by copper-mediated redox cycling of para- and ortho-hydroquinones
    • Wang X.J., Hayes J.D., Higgins L.J., Wolf C.R., Dinkova-Kostova A.T. Activation of the NRF2 signaling pathway by copper-mediated redox cycling of para- and ortho-hydroquinones. Chemistry & Biology 2010, 1775-1785.
    • (2010) Chemistry & Biology , pp. 1775-1785
    • Wang, X.J.1    Hayes, J.D.2    Higgins, L.J.3    Wolf, C.R.4    Dinkova-Kostova, A.T.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.