Outbreaks of virulent diarrheagenic Escherichia coli - are we in control?

BMC Medicine

Volumn 10, Issue , 2012, Pages

  Werber, Dirk ^a   Krause, Gérard ^a   Frank, Christina ^a   Fruth, Angelika ^a   Flieger, Antje ^a   Mielke, Martin ^a   Schaade, Lars ^a   Stark, Klaus ^a  

^a ROBERT KOCH INSTITUTE   (Germany)

Author keywords

Disease outbreaks; E. coli; Epidemiology; Escherichia coli o157; Public health

Indexed keywords

BACTERIAL VIRULENCE; DIARRHEAGENIC ESCHERICHIA COLI; DISEASE SURVEILLANCE; EPIDEMIC; ESCHERICHIA COLI INFECTION; FOOD INTAKE; FOOD POISONING; GERMANY; HUMAN; INFECTION CONTROL; NONHUMAN; NOTE; PUBLIC HEALTH; SEROTYPE; MICROBIOLOGY; PATHOGENICITY; REVIEW; SHIGA TOXIN PRODUCING ESCHERICHIA COLI; STATISTICS; VIRULENCE;

DISEASE OUTBREAKS; ESCHERICHIA COLI INFECTIONS; GERMANY; HUMANS; PUBLIC HEALTH; SHIGA-TOXIGENIC ESCHERICHIA COLI; VIRULENCE;

EID: 84856482240     PISSN: None     EISSN: 17417015     Source Type: Journal    
DOI: 10.1186/1741-7015-10-11     Document Type: Note

References (50)

1. Riley LW, Remis RS, Helgerson SD, McGee HB, Wells JG, Davis BR, Hebert RJ, Olcott ES, Johnson LM, Hargrett NT, Blake PA, Cohen ML. Hemorrhagic colitis associated with a rare Escherichia coli serotype. N Engl J Med 1983, 308:681-685. 10.1056/NEJM198303243081203, 6338386.
2. Goldwater PN. Pathogenesis and Treatment strategies. BMC Medicine
3. Gould LH, Demma L, Jones TF, Hurd S, Vugia DJ, Smith K, Shiferaw B, Segler S, Palmer A, Zansky S, Griffin PM. Hemolytic uremic syndrome and death in persons with Escherichia coli O157:H7 infection, foodborne diseases active surveillance network sites, 2000-2006. Clin Infect Dis 2009, 49:480-1485. 10.1086/600821, 19586398.
4. Gerber A, Karch H, Allerberger F, Verweyen HM, Zimmerhackl LB. Clinical course and the role of shiga toxin-producing Escherichia coli infection in the hemolytic-uremic syndrome in pediatric patients, 1997-2000, in Germany and Austria: a prospective study. J Infect Dis 2002, 186:493-500. 10.1086/341940, 12195376.
5. Alpers K, Werber D, Frank C, Koch J, Friedrich AW, Karch H, An Der Heiden M, Prager R, Fruth A, Bielaszewska M, Morlock G, Heissenhuber A, Diedler A, Gerber A, Ammon A. Sorbitol-fermenting enterohaemorrhagic Escherichia coli O157:H- causes another outbreak of haemolytic uraemic syndrome in children. Epidemiol Infect 2009, 137:389-395. 10.1017/S0950268808001465, 19021923.
6. Konowalchuk J, Speirs JI, Stavric S. Vero response to a cytotoxin of Escherichia coli. Infect Immun 1977, 18:775-779. 421302, 338490.
7. Tarr PI, Gordon CA, Chandler WL. Shiga-toxin-producing Escherichia coli and haemolytic uraemic syndrome. Lancet 2005, 365:1073-1086.
8. Werber D, Fruth A, Heissenhuber A, Wildner M, Prager R, Tschape H, Ammon A. Shiga toxin-producing Escherichia coli O157 more frequently cause bloody diarrhea than do non-O157 strains. J Infect Dis 2004, 189:1335-1336. 10.1086/382282, 15031806.
9. Werber D, Behnke SC, Fruth A, Merle R, Menzler S, Glaser S, Kreienbrock L, Prager R, Tschape H, Roggentin P, Bockemuhl J, Ammon A. Shiga Toxin-producing Escherichia coli Infection in Germany-Different Risk Factors for Different Age Groups. Am J Epidemiol 2007, 165:425-434.
10. Robert Koch Institute EHEC-Erkrankung. Infektionsepidemiologisches Jahrbuch meldepflichtiger Krankheiten für 2010 2011, 80-84. Berlin: AZ Druck und Datentechnik GmbH, Robert Koch Institute, Robert Koch Institute.
11. Brooks JT, Sowers EG, Wells JG, Greene KD, Griffin PM, Hoekstra RM, Strockbine NA. Non-O157 Shiga toxin-producing Escherichia coli infections in the United States, 1983-2002. J Infect Dis 2005, 192:1422-1429. 10.1086/466536, 16170761.
12. Werber D, Frank C, Wadl M, Karch H, Fruth A, Stark K. Looking for tips to find icebergs-surveillance of haemolytic uraemic syndrome to detect outbreaks of Shiga toxin-producing E. coli infection. Euro Surveill 2008, 13:pii:8053.
13. Hoefer D, Hurd S, Medus C, Cronquist A, Hanna S, Hatch J, Hayes T, Larson K, Nicholson C, Wymore K, Tobin-D'Angelo M, Strockbine N, Snippes P, Atkinson R, Griffin PM, Gould LH. Laboratory practices for the identification of Shiga toxin-producing Escherichia coli in the United States, FoodNet sites, 2007. Foodborne Pathog Dis 2011, 8:555-560. 10.1089/fpd.2010.0764, 21186994.
14. Wiedenbeck J, Cohan FM. Origins of bacterial diversity through horizontal genetic transfer and adaptation to new ecological niches. FEMS Microbiol Rev 2011, 35:957-976. 10.1111/j.1574-6976.2011.00292.x, 21711367.
15. Robins-Browne RM. The relentless evolution of pathogenic Escherichia coli. Clin Infect Dis 2005, 41:793-794. 10.1086/432725, 16107975.
16. Michino H, Araki K, Minami S, Takaya S, Sakai N, Miyazaki M, Ono A, Yanagawa H. Massive outbreak of Escherichia coli O157:H7 infection in schoolchildren in Sakai City, Japan, associated with consumption of white radish sprouts. Am J Epidemiol 1999, 150:787-796.
17. Matsell DG, White CT. An outbreak of diarrhea-associated childhood hemolytic uremic syndrome: the Walkerton epidemic. Kidney Int Suppl 2009, (112):S35-S37.
18. Bell BP, Goldoft M, Griffin PM, Davis MA, Gordon DC, Tarr PI, Bartleson CA, Lewis JH, Barrett TJ, Wells JG, et al. A multistate outbreak of Escherichia coli O157:H7-associated bloody diarrhea and hemolytic uremic syndrome from hamburgers. The Washington experience. JAMA 1994, 272:1349-1353. 10.1001/jama.1994.03520170059036, 7933395.
19. Ahn CK, Klein E, Tarr PI. Isolation of patients acutely infected with Escherichia coli O157:H7: low-tech, highly effective prevention of hemolytic uremic syndrome. Clin Infect Dis 2008, 46:1197-1199. 10.1086/587664, 18444855.
20. Frank C, Werber D, Cramer JP, Askar M, Faber M, Heiden MA, Bernard H, Fruth A, Prager R, Spode A, Wadl M, Zoufaly A, Jordan S, Kemper MJ, Follin P, Muller L, King LA, Rosner B, Buchholz U, Stark K, Krause G, . HUS Investigation Team Epidemic Profile of Shiga-Toxin-Producing Escherichia coli O104:H4 Outbreak in Germany. N Engl J Med 2011, 365:1771-1780. 10.1056/NEJMoa1106483, 21696328, HUS Investigation Team.
21. Harendza S. "HUS diary" of a German nephrologist during the current EHEC outbreak in Europe. Kidney Int 2011, 80:687-689. 10.1038/ki.2011.238, 21734639.
22. Rohde H, Qin J, Cui Y, Li D, Loman NJ, Hentschke M, Chen W, Pu F, Peng Y, Li J, Xi F, Li S, Li Y, Zhang Z, Yang X, Zhao M, Wang P, Guan Y, Cen Z, Zhao X, Christner M, Kobbe R, Loos S, Oh J, Yang L, Danchin A, Gao GF, Song Y, Li Y, Yang H, et al. Open-source genomic analysis of Shiga-toxin-producing E. coli O104:H4. N Engl J Med 2011, 365:718-724. 10.1056/NEJMoa1107643, 21793736.
23. Mellmann A, Harmsen D, Cummings CA, Zentz EB, Leopold SR, Rico A, Prior K, Szczepanowski R, Ji Y, Zhang W, McLaughlin SF, Henkhaus JK, Leopold B, Bielaszewska M, Prager R, Brzoska PM, Moore RL, Guenther S, Rothberg JM, Karch H. Prospective Genomic Characterization of the German Enterohemorrhagic Escherichia coli O104:H4 Outbreak by Rapid Next Generation Sequencing Technology. PLoS One 2011, 6:e22751. 10.1371/journal.pone.0022751, 3140518, 21799941.
24. Brzuszkiewicz E, Thurmer A, Schuldes J, Leimbach A, Liesegang H, Meyer FD, Boelter J, Petersen H, Gottschalk G, Daniel R. Genome sequence analyses of two isolates from the recent Escherichia coli outbreak in Germany reveal the emergence of a new pathotype: Entero-Aggregative-Haemorrhagic Escherichia coli (EAHEC). Arch Microbiol 2011, 193:883-891. 10.1007/s00203-011-0725-6, 3219860, 21713444.
25. Rasko DA, Webster DR, Sahl JW, Bashir A, Boisen N, Scheutz F, Paxinos EE, Sebra R, Chin CS, Iliopoulos D, Klammer A, Peluso P, Lee L, Kislyuk AO, Bullard J, Kasarskis A, Wang S, Eid J, Rank D, Redman JC, Steyert SR, Frimodt-Moller J, Struve C, Petersen AM, Krogfelt KA, Nataro JP, Schadt EE, Waldor MK. Origins of the E. coli strain causing an outbreak of Hemolytic-Uremic Syndrome in Germany. N Engl J Med 2011, 365:709-717. 10.1056/NEJMoa1106920, 21793740.
26. Bielaszewska M, Mellmann A, Zhang W, Kock R, Fruth A, Bauwens A, Peters G, Karch H. Characterisation of the Escherichia coli strain associated with an outbreak of haemolytic uraemic syndrome in Germany, 2011: a microbiological study. Lancet Infect Dis 2011, 11:671-676.
27. Buchholz U, Bernard H, Werber D, Bohmer MM, Remschmidt C, Wilking H, Delere Y, Heiden MA, Adlhoch C, Dreesman J, Ehlers J, Ethelberg S, Faber M, Frank C, Fricke G, Greiner M, Hohle M, Ivarsson S, Jark U, Kirchner M, Koch J, Krause G, Luber P, Rosner B, Stark K, Kuhne M. German Outbreak of Escherichia coli O104:H4 Associated with Sprouts. N Engl J Med 2011, 365:1763-1770. 10.1056/NEJMoa1106482, 22029753.
28. Frank C, Faber MS, Askar M, Bernard H, Fruth A, Gilsdorf A, Hohle M, Karch H, Krause G, Prager R, Spode A, Stark K, Werber D. Large and ongoing outbreak of haemolytic uraemic syndrome, Germany, May 2011. Euro Surveill 2011, 16:pii:19878.
29. Tracing seeds, in particular fenugreek (Trigonella foenum-graecum) seeds, in relation to the Shiga toxin-producing E. coli (STEC) O104:H4 2011 Outbreaks in Germany and France. European Food Safety Authority 2011 July 5. Available from: URL:http://www.efsa.europa.eu/en/supporting/doc/176e.pdf
30. Federal Institute for Risk Assessment Bedeutung von Sprossen und Keimlingen sowie Samen zur Sprossenherstellung im EHEC O104:H4 Ausbruchsgeschehen im Mai und Juni 2011. Federal Institute for Risk assessment 2011 Available from: URL: http://www.bfr.bund.de/cm/343/bedeutung_von_sprossen_und_keimlingen_sowie_samen_zur_sprossenherstellung_im_ehec_o104_h4_ausbruchsgeschehen_im_mai_und_juni_2011.pdf, Federal Institute for Risk Assessment.
31. Tauxe RV. Emerging foodborne diseases: an evolving public health challenge. Emerg Infect Dis 1997, 3:425-434. 10.3201/eid0304.970403, 2640074, 9366593.
32. Hauri A, Gotsch U, Strotmann I, Krahn J, Bettge-Weller G, Westbrock H, Bellinger O, Uphoff H. Secondary transmissions during the outbreak of Shiga toxin-producing Escherichia coli O104 in Hesse, Germany, 2011. Euro Surveill 2011, 16:pii:19937.
33. Werber D, Fruth A, Frank C, Altmann D, Stark K. Surveillance von STEC-Erkrankungen in Deutschland 2001-2009: Time for a change. Dritter EHEC-Workshop, 2010 2010, 16. Bayerisches Landesamt für Gesundheit und Lebensmittelsicherheit, Busch U.
34. Bugarel M, Beutin L, Martin A, Gill A, Fach P. Micro-array for the identification of Shiga toxin-producing Escherichia coli (STEC) seropathotypes associated with Hemorrhagic Colitis and Hemolytic Uremic Syndrome in humans. Int J Food Microbiol 2010, 142:318-329. 10.1016/j.ijfoodmicro.2010.07.010, 20675003.
35. Swaminathan B, Gerner-Smidt P, Ng LK, Lukinmaa S, Kam KM, Rolando S, Gutierrez EP, Binsztein N. Building PulseNet International: an interconnected system of laboratory networks to facilitate timely public health recognition and response to foodborne disease outbreaks and emerging foodborne diseases. Foodborne Pathog Dis 2006, 3:36-50. 10.1089/fpd.2006.3.36, 16602978.
36. Tauxe RV. Molecular subtyping and the transformation of public health. Foodborne Pathog Dis 2006, 3:4-8. 10.1089/fpd.2006.3.4, 16602974.
37. Salmon RL, Evans MR, Mason BW, Werber D. Bloody diarrhoea: Test early for verotoxin producing Escherichia coli. BMJ 2008, 336:1147-1148. 2394596, 18497385.
38. Wadl M, Rieck T, Nachtnebel M, Greutelaers B, An Der Heiden M, Altmann D, Hellenbrand W, Faber M, Frank C, Schweickert B, Krause G, Benzler J, Eckmanns T. Enhanced surveillance during a large outbreak of bloody diarrhoea and haemolytic uraemic syndrome caused by Shiga toxin/verotoxin-producing Escherichia coli in Germany, May to June 2011. Euro Surveill 2011, 16:pii:19893.
39. King LA, Mailles A, Mariani-Kurkdjian P, Vernozy-Rozand C, Montet MP, Grimont F, Pihier N, Devalk H, Perret F, Bingen E, Espie E, Vaillant V. Community-wide outbreak of Escherichia coli O157:H7 associated with consumption of frozen beef burgers. Epidemiol Infect 2009, 137:889-896. 10.1017/S0950268808001490, 18945376.
40. Community outbreak of hemolytic uremic syndrome attributable to Escherichia coli O111:NM-South Australia 1995. MMWR Morb Mortal Wkly Rep 1995, 44:550-558.
41. Nielsen S, Frank C, Fruth A, Spode A, Prager R, Graff A, Plenge-Bonig A, Loos S, Lutgehetmann M, Kemper MJ, Muller-Wiefel DE, Werber D. Desperately seeking diarrhoea: outbreak of haemolytic uraemic syndrome caused by emerging sorbitol-fermenting shiga toxin-producing Escherichia coli O157:H-, Germany, 2009. Zoonoses Public Health 2011, 58:567-572. 10.1111/j.1863-2378.2011.01405.x, 21824358.
42. Mody RK, Greene SA, Gaul L, Sever A, Pichette S, Zambrana I, Dang T, Gass A, Wood R, Herman K, Cantwell LB, Falkenhorst G, Wannemuehler K, Hoekstra RM, McCullum I, Cone A, Franklin L, Austin J, Delea K, Behravesh CB, Sodha SV, Yee JC, Emanuel B, Al-Khaldi SF, Jefferson V, Williams IT, Griffin PM, Swerdlow DL. National outbreak of Salmonella serotype saintpaul infections: importance of Texas restaurant investigations in implicating jalapeno peppers. PLoS One 2011, 6:e16579. 10.1371/journal.pone.0016579, 3044132, 21373185.
43. Fretz R, Pichler J, Sagel U, Much P, Ruppitsch W, Pietzka AT, Stoger A, Huhulescu S, Heuberger S, Appl G, Werber D, Stark K, Prager R, Flieger A, Karpiskova R, Pfaff G, Allerberger F. Update: multinational listeriosis outbreak due to 'Quargel', a sour milk curd cheese, caused by two different L. monocytogenes serotype 1/2a strains, 2009-2010. Euro Surveill 2010, 15:pii:19543.
44. Salmonella montevideo infections associated with salami products made with contaminated imported black and red pepper -- United States, July 2009-April 2010. MMWR Morb Mortal Wkly Rep 2010, 59:1647-1650.
45. Ethelberg S, Smith B, Torpdahl M, Lisby M, Boel J, Jensen T, Molbak K. An outbreak of Verocytotoxin-producing Escherichia coli O26:H11 caused by beef sausage, Denmark 2007. Euro Surveill 2007, 12:E070531.4.
46. Keene WE, Hedberg K, Herriott DE, Hancock DD, McKay RW, Barrett TJ, Fleming DW. A prolonged outbreak of Escherichia coli O157:H7 infections caused by commercially distributed raw milk. J Infect Dis 1997, 176:815-818. 10.1086/517310, 9291342.
47. Outbreak of Salmonella serotype Enteritidis infections associated with raw almonds-United States and Canada, 2003-2004. MMWR Morb Mortal Wkly Rep 2004, 53:484-487.
48. Werber D, Mason BW, Evans MR, Salmon RL. Preventing household transmission of Shiga toxin-producing Escherichia coli O157 infection: promptly separating siblings might be the key. Clin Infect Dis 2008, 46:1189-196. 10.1086/587670, 18444854.
49. Pollock KG, Beattie TJ, Reynolds B, Stewart A, Cowden JM. Clinical management of children with suspected or confirmed E. coli O157 infection. Scott Med J 2007, 52:5-7.
50. Locking ME, Pollock KG, Allison LJ, Rae L, Hanson MF, Cowden JM. Escherichia coli O157 infection and secondary spread, Scotland, 1999-2008. Emerg Infect Dis 2011, 17:524-527. 3165990, 21392450.