Bisphenol a induces oxidative stress and decreases levels of insulin receptor substrate 2 and glucose transporter 8 in rat testis

Reproductive Sciences

Volumn 19, Issue 2, 2012, Pages 163-172

  D'Cruz, Shereen C ^a   Jubendradass, R ^a   Mathur, Premendu P ^a  

^a PONDICHERRY UNIVERSITY   (India)

Author keywords

bisphenol A; glucose transporter 8; insulin receptor substrate 2; oxidative stress; testis

Indexed keywords

4,4' ISOPROPYLIDENEDIPHENOL; 6 PHOSPHOFRUCTOKINASE; ESTRADIOL; GLUCOSE; GLUCOSE TRANSPORTER; GLUCOSE TRANSPORTER 8; HEXOKINASE; HYDROGEN PEROXIDE; INSULIN; INSULIN RECEPTOR SUBSTRATE 2; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; ENZYME ACTIVITY; GLUCOSE BLOOD LEVEL; GLUCOSE METABOLISM; IMMUNOLOCALIZATION; INSULIN BLOOD LEVEL; MALE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SPERMATID; SPERMATOCYTE; TESTIS; WESTERN BLOTTING;

ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; ENDOCRINE DISRUPTORS; GLUCOSE TRANSPORT PROTEINS, FACILITATIVE; INSULIN RECEPTOR SUBSTRATE PROTEINS; MALE; OXIDATIVE STRESS; PHENOLS; RATS; RATS, WISTAR; TESTIS;

EID: 84858003099     PISSN: 19337191     EISSN: 19337205     Source Type: Journal    
DOI: 10.1177/1933719111415547     Document Type: Article

References (47)

1. Chapin RE, Adams J, Boekelheide K, et al. NTP-CERHR expert panel report on the reproductive and developmental toxicity of bisphenol A. Birth Defects Res B Dev Reprod Toxicol. 2008; 83(3):157-395. (Pubitemid 352002664)
2. Chitra KC, Latchoumycandane C, Mathur PP. Induction of oxidative stress by bisphenol A in the epididymal sperm of rats. Toxicology. 2003;185(1-2):119- 127. (Pubitemid 36050735)
3. vom Saal FS, Cooke PS, Buchanan DL, et al. A physiologically based approach to the study of bisphenol A and other estrogenic chemicals on the size of reproductive organs, daily sperm production, and behavior. Toxicol Ind Health. 1998;14(1-2):239-260. (Pubitemid 28044978)
4. Li MW, Mruk DD, Lee WM, Cheng CY. Disruption of the bloodtestis barrier integrity by bisphenol A in vitro: is this a suitable model for studying blood-testis barrier dynamics? Int J Biochem Cell Biol. 2009;41(11):2302-2314.
5. Alonso-Magdalena P, Morimoto S, Ripoll C, Fuentes E, Nadal A. The estrogenic effect of bisphenol A disrupts pancreatic beta-cell function in vivo and induces insulin resistance. Environ Health Perspect. 2006;114(1):106-112. (Pubitemid 43056876)
6. Alonso-Magdalena P, Ropero AB, Soriano S, Quesada I, Nadal A. Bisphenol-A: a new diabetogenic factor? Hormones (Athens). 2010;9(2):118-126.
7. Rommerts FF, Cooke BA, Van der Kemp JW, Van der Molen HJ. Effect of luteinizing hormone on 3′,5′-cyclic AMP and testosterone production in isolated interstitial tissue of rat testis. FEBS Lett. 1973;33(1):114-118.
8. Murono EP, Lin T, Osterman J, Nankin HR. Relationship between inhibition of interstitial cell testosterone synthesis by cytochalasin B and glucose. Biochem Biophys Res Commun. 1982;104(1):299-306. (Pubitemid 12146308)
9. Ibberson M, Uldry M, Thorens B. GLUTX1, a novel mammalian glucose transporter expressed in the central nervous system and insulin-sensitive tissues. J Biol Chem. 2000;275(7):4607-4612. (Pubitemid 30108844)
10. Kokk K, Verajankorva E, Laato M, Wu XK, Tapfer H, Pollanen P. Expression of insulin receptor substrates 1-3, glucose transporters GLUT-1-4, signal regulatory protein 1alpha, phosphatidylinositol 3-kinase and protein kinase B at the protein level in the human testis. Anat Sci Int. 2005;80(2):91-96. (Pubitemid 40852073)
11. Cai D, Yuan M, Frantz DF, et al. Local and systemic insulin resistance resulting from hepatic activation of IKK-beta and NF-kappaB. Nat Med. 2005;11(2):183-190. (Pubitemid 40321354)
12. Park SY, Choi GH, Choi HI, Ryu J, Jung CY, Lee W. Depletion of mitochondrial DNA causes impaired glucose utilization and insulin resistance in L6 GLUT4myc myocytes. J Biol Chem. 2005; 280(11):9855-9864. (Pubitemid 40395832)
13. Archuleta TL, Lemieux AM, Saengsirisuwan V, et al. Oxidant stress-induced loss of IRS-1 and IRS-2 proteins in rat skeletal muscle: role of p38 MAPK. Free Radic Biol Med. 2009;47(10): 1486-1493.
14. Ohta Y, Kinugawa S,Matsushima S, et al. Oxidative stress impairs insulin signal in skeletal muscle and causes insulin resistance in post-infarct heart failure. Am J Physiol Heart Circ Physiol. 2011; doi: 10.1152/01185.2009.
15. Bindhumol V, Chitra KC, Mathur PP. Bisphenol A induces reactive oxygen species generation in the liver of male rats. Toxicology. 2003;188(2-3):117-124. (Pubitemid 36588894)
16. Kabuto H, Amakawa M, Shishibori T. Exposure to bisphenol A during embryonic/fetal life and infancy increases oxidative injury and causes underdevelopment of the brain and testis in mice. Life Sci. 2004;74(24):2931- 2940. (Pubitemid 38402291)
17. Chitra KC, Mathur PP. Induction of oxidative stress in epididymis of rats after short-term exposure to bisphenol A. Arch Med Res. 2003;1(1):1-16.
18. Sakaue M, Ohsako S, Ishimura R, et al. Bisphenol-A affects spermatogenesis in the adult rat even at a low dose. J Occup Health. 2001;43(4):185-190. (Pubitemid 32785817)
19. vom Saal FS, Cooke PS, Buchanan DL, et al. A physiologically based approach to the study of bisphenol A and other estrogenic chemicals on the size of reproductive organs, daily sperm production, and behavior. Toxicol Ind Health. 1998;14(1-2):239-260. (Pubitemid 28044978)
20. CPCSEA. CPCSEA guidelines for laboratory animal facility. Indian J Pharmacol. 2003;35(4):257-274.
21. EFSA. Opinion of the scientific panel on food additives, flavourings, processing aids and materials in contact with food on a request from the commission related to 2,2-bis(4-hydroxyphenyl) propane (bisphenol A). EFSA J. 2006;428:1-75.
22. Melner MH, Abney TO. The direct effect of 17 beta-estradiol on LH-stimulated testosterone production in hypophysectomized rats. J Steroid Biochem. 1980;13(2):203-210. (Pubitemid 10079036)
23. Gordon MN, Osterburg HH, May PC, Finch CE. Effective oral administration of 17 beta-estradiol to female C57BL/6J mice through the drinking water. Biol Reprod. 1986;35(5):1088-1095. (Pubitemid 17010451)
24. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ. Protein measurement with the Folin phenol reagent. J Biol Chem. 1951; 193(1):265-275.
25. Trinder P. Determination of blood glucose using an oxidaseperoxidase system with a non-carcinogenic chromogen. J Clin Pathol. 1969;22(2):158-161.
26. Pick E, Keisari Y. Superoxide anion and hydrogen peroxide production by chemically elicited peritoneal macrophages - induction by multiple nonphagocytic stimuli. Cell Immunol. 1981; 59(2):301-318. (Pubitemid 11096681)
27. Bergmeyer HU, Grabl M, Walter HE. Methods of Enzymatic Analysis. Deerfield Beach, FL: Verlag Chemie; 1983:222-223.
28. Narabayashi H, Lawson JW, Uyeda K. Regulation of phosphofructokinase in perfused rat heart. Requirement for fructose 2,6-bisphosphate and a covalent modification. J Biol Chem. 1985;260(17):9750-9758.
29. Laemmli UK. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature. 1970;227(5259): 680-685.
30. Cranmer M, Louie S, Kennedy RH, Kern PA, Fonseca VA. Exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) is associated with hyperinsulinemia and insulin resistance. Toxicol Sci. 2000; 56(2):431-436. (Pubitemid 30497514)
31. Turyk M, Anderson H, Knobeloch L, Imm P, Persky V. Organochlorine exposure and incidence of diabetes in a cohort of Great Lakes sport fish consumers. Environ Health Perspect. 2009; 117(7):1076-1082.
32. Nadal A, Alonso-Magdalena P, Soriano S, Quesada I, Ropero AB. The pancreatic beta-cell as a target of estrogens and xenoestrogens: Implications for blood glucose homeostasis and diabetes. Mol Cell Endocrinol. 2009;304(1-2):63-68.
33. Godsland IF. Oestrogens and insulin secretion. Diabetologia. 2005;48(11):2213-2220. (Pubitemid 41618909)
34. Kokk K, Verajankorva E, Wu XK, et al. Expression of insulin signaling transmitters and glucose transporters at the protein level in the rat testis. Ann N Y Acad Sci. 2007;1095:262-273. (Pubitemid 47092458)
35. Adachi T, Yasuda K, Mori C, et al. Promoting insulin secretion in pancreatic islets by means of bisphenol A and nonylphenol via intracellular estrogen receptors. Food Chem Toxicol. 2005; 43(5):713-719. (Pubitemid 40381174)
36. Wolff SP, Bascal ZA, Hunt JV. "Autoxidative glycosylation": free radicals and glycation theory. Prog Clin Biol Res. 1989; 304:259-275.
37. Nishikawa T, Edelstein D, Du XL, et al. Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage. Nature. 2000;404(6779):787-790. (Pubitemid 30212409)
38. Kaneto H, Fujii J, Suzuki K, et al. DNA cleavage induced by glycation of Cu, Zn-superoxide dismutase. Biochem J. 1994;304(Pt 1): 219-225. (Pubitemid 24354248)
39. Shin AH, Oh CJ, Park JW. Glycation-induced inactivation of antioxidant enzymes and modulation of cellular redox status in lens cells. Arch Pharm Res. 2006;29(7):577-581.
40. Nakamura M, Okinaga S, Arai K. Metabolism of pachytene primary spermatocytes from rat testes: pyruvate maintenance of adenosine triphosphate level. Biol Reprod. 1984;30(5):1187-1197. (Pubitemid 14056537)
41. Colussi C, Albertini MC, Coppola S, Rovidati S, Galli F, Ghibelli L. H2O2-induced block of glycolysis as an active ADP-ribosylation reaction protecting cells from apoptosis. FASEB J. 2000;14(14):2266-2276.
42. Hegde KR, Kovtun S, Varma SD. Inhibition of glycolysis in the retina by oxidative stress: prevention by pyruvate. Mol Cell Biochem. 2010;343(1-2):101- 105.
43. Janero DR, Hreniuk D, Sharif HM. Hydroperoxide-induced oxidative stress impairs heart muscle cell carbohydrate metabolism. Am J Physiol. 1994;266(1 Pt 1):C179-188. (Pubitemid 24058299)
44. Huang X, Vaag A, Hansson M, Groop L. Down-regulation of insulin receptor substrates (IRS)-1 and IRS-2 and Src homologous and collagen-like protein Shc gene expression by insulin in skeletal muscle is not associated with insulin resistance or type 2 diabetes. J Clin Endocrinol Metab. 2002;87(1):255-259. (Pubitemid 34084699)
45. Zhang J, Ou J, Bashmakov Y, Horton JD, Brown MS, Goldstein JL. Insulin inhibits transcription of IRS-2 gene in rat liver through an insulin response element (IRE) that resembles IREs of other insulin-repressed genes. Proc Natl Acad Sci U S A. 2001;98(7): 3756-3761. (Pubitemid 32249844)
46. Ibberson M, Riederer BM, Uldry M, Guhl B, Roth J, Thorens B. Immunolocalization of GLUTX1 in the testis and to specific brain areas and vasopressin-containing neurons. Endocrinology. 2002; 143(1):276-284. (Pubitemid 34056429)
47. Doege H, Schurmann A, Bahrenberg G, Brauers A, Joost HG. GLUT8, a novel member of the sugar transport facilitator family with glucose transport activity. J Biol Chem. 2000;275(21): 16275-16280. (Pubitemid 30366941)