The discovery of split genes and RNA splicing

Trends in Biochemical Sciences

Volumn 30, Issue 6, 2005, Pages 279-281

  Sharp, Phillip A ^a  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CONFERENCE PAPER; CYTOPLASM; DNA SEQUENCE; DNA STRUCTURE; GENE MUTATION; GENETIC ANALYSIS; HUMAN; MOLECULAR RECOGNITION; NONHUMAN; PRIORITY JOURNAL; RNA SPLICING;

ALTERNATIVE SPLICING; ANIMALS; CELL NUCLEUS; ENHANCER ELEMENTS (GENETICS); RNA PRECURSORS; RNA SPLICING; RNA, MESSENGER; SPLICEOSOMES; VERTEBRATES;

EID: 20444390475     PISSN: 09680004     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tibs.2005.04.002     Document Type: Conference Paper

References (20)

1. S.M. Berget Spliced segments at the 5′ terminus of adenovirus 2 late mRNA Proc. Natl. Acad. Sci. U. S. A. 74 1977 3171 3175
2. L.T. Chow An amazing sequence arrangement at the 5′ ends of adenovirus 2 messenger RNA Cell 12 1977 1 8
3. R. Treisman Specific transcription and RNA splicing defects in five cloned β-thalassaemia genes Nature 302 1983 591 596
4. R. Breathnach, and P. Chambon Organization and expression of eucaryotic split genes coding for proteins Annu. Rev. Biochem. 50 1981 349 383
5. R.A. Padgett Splicing of messenger RNA precursors Annu. Rev. Biochem. 55 1986 1119 1150
6. M.R. Lerner Are snRNPs involved in splicing? Nature 283 1980 220 224
7. J. Rappsilber Large-scale proteomic analysis of the human spliceosome Genome Res. 12 2002 1231 1245
8. S.L. Hall, and R.A. Padgett Conserved sequences in a class of rare eukaryotic nuclear introns with non-consensus splice sites J. Mol. Biol. 239 1994 357 365
9. B.L. Robberson Exon definition may facilitate splice site selection in RNAs with multiple exons Mol. Cell. Biol. 10 1990 84 94
10. D.L. Black Mechanisms of alternative pre-messenger RNA splicing Annu. Rev. Biochem. 72 2003 291 336
11. W.G. Fairbrother Predictive identification of exonic splicing enhancers in human genes Science 297 2002 1007 1013
12. Z. Wang Systematic identification and analysis of exonic splicing silencers Cell 119 2004 831 845
13. T. Maniatis, and R. Reed An extensive network of coupling among gene expression machines Nature 416 2002 499 506
14. A.R. Kornblihtt Multiple links between transcription and splicing RNA 10 2004 1489 1498
15. H. Le Hir The spliceosome deposits multiple proteins 20-24 nucleotides upstream of mRNA exon-exon junctions EMBO J. 19 2000 6860 6869
16. A. Nott Splicing enhances translation in mammalian cells: an additional function of the exon junction complex Genes Dev. 18 2004 210 222
17. S. Valadkhan Young Scientist Award assay winner. Construction of a minimal, protein free spliceosome Science 307 2005 863 864
18. G.W. Yeo Identification and analysis of alternative splicing events conserved in human and mouse Proc. Natl. Acad. Sci. U. S. A. 102 2005 2850 2855
19. H. Ponta CD44: from adhesion molecules to signalling regulators Nat. Rev. Mol. Cell Biol. 4 2003 33 45
20. H. Kim Estimating rates of alternative splicing in mammals and invertebrates Nat. Genet. 36 2004 915 916