CD4-mediated regulatory T-cell activation inhibits the development of disease in a humanized mouse model of allergic airway disease

Journal of Allergy and Clinical Immunology

Volumn 129, Issue 2, 2012, Pages

  Martin, Helen ^a   Reuter, Sebastian ^a   Dehzad, Nina ^a   Heinz, Anke ^a   Bellinghausen, Iris ^a   Saloga, Joachim ^a   Haasler, Ina ^a   Korn, Stephanie ^a   Jonuleit, Helmut ^a   Buhl, Roland ^a   Becker, Christian ^a   Taube, Christian ^a,b  

^a JOHANNES GUTENBERG UNIVERSITY   (Germany)

^b LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

AHR; Humanized animal model; pulmonary inflammation; regulatory T cells

Indexed keywords

ALLERGEN; CD4 ANTIGEN; GLYCOPROTEIN GP 120; IMMUNOGLOBULIN E; INTERLEUKIN 4; PROTEIN KINASE LCK;

ADULT; AIRWAY RESISTANCE; ALLERGIC ASTHMA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIRCH; CD3+ T LYMPHOCYTE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL INFILTRATION; CELL ISOLATION; CELL THERAPY; CELL TRANSFER; CONTROLLED STUDY; DISEASE CONTROL; DISEASE COURSE; EXPOSURE; FEMALE; FLOW CYTOMETRY; GRAFT VERSUS HOST REACTION; HISTOLOGY; HUMAN; HUMAN CELL; IN VIVO STUDY; LUNG; LUNG FUNCTION; LUNG INFILTRATE; LUNG LAVAGE; LYMPHOCYTE SUBPOPULATION; MACROPHAGE; MALE; MOUSE; NEUTROPHIL; NONHUMAN; OUTCOME ASSESSMENT; PERIPHERAL BLOOD MONONUCLEAR CELL; PNEUMONIA; POLLEN; PRIORITY JOURNAL; PROVOCATION TEST; REGULATORY T LYMPHOCYTE; RESPIRATORY TRACT ALLERGY; SENSITIZATION; T LYMPHOCYTE ACTIVATION;

EID: 84856415601     PISSN: 00916749     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2011.09.038     Document Type: Article

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