Alcohol Dehydrogenase-1B Arg47His Polymorphism and Upper Aerodigestive Tract Cancer Risk: A Meta-Analysis Including 24,252 Subjects

Alcoholism: Clinical and Experimental Research

Volumn 36, Issue 2, 2012, Pages 272-278

  Guo, Haipeng ^a   Zhang, Guohong ^b   Mai, Ruiqin ^a  

^a SHANTOU UNIVERSITY MEDICAL COLLEGE   (China)

^b SHANTOU UNIVERSITY   (China)

Author keywords

Alcohol Dehydrogenase 1B; Genetic Susceptibility; His47Arg Polymorphism; Upper Aerodigestive Tract Cancers

Indexed keywords

ALCOHOL DEHYDROGENASE; ALCOHOL DEHYDROGENASE 1B; ALCOHOL DEHYDROGENASE 2; UNCLASSIFIED DRUG;

ALLELE; ARTICLE; CANCER RISK; DIGESTIVE SYSTEM CANCER; DRINKING BEHAVIOR; GENETIC ASSOCIATION; GENETIC HETEROGENEITY; GENETIC POLYMORPHISM; GENETIC VARIABILITY; GENOTYPE; GENOTYPE ENVIRONMENT INTERACTION; HETEROZYGOTE; HUMAN; PRIORITY JOURNAL; SENSITIVITY ANALYSIS; UPPER AERODIGESTIVE TRACT CANCER;

ALCOHOL DEHYDROGENASE; ALCOHOL DRINKING; ALLELES; CONFIDENCE INTERVALS; DATA INTERPRETATION, STATISTICAL; DIGESTIVE SYSTEM NEOPLASMS; GENE-ENVIRONMENT INTERACTION; GENETIC VARIATION; HETEROZYGOTE; HUMANS; ODDS RATIO; POLYMORPHISM, GENETIC; PUBLICATION BIAS; RISK ASSESSMENT;

EID: 84856367240     PISSN: 01456008     EISSN: 15300277     Source Type: Journal    
DOI: 10.1111/j.1530-0277.2011.01621.x     Document Type: Article

References (36)

1. Akbari MR, Malekzadeh R, Shakeri R, Nasrollahzadeh D, Foumani M, Sun Y, Pourshams A, Sadjadi A, Jafari E, Sotoudeh M, Kamangar F, Boffetta P, Dawsey SM, Ghadirian P, Narod SA (2009) Candidate gene association study of esophageal squamous cell carcinoma in a high-risk region in Iran. Cancer Res69:7994-8000.
2. Allen NE, Beral V, Casabonne D, Kan SW, Reeves GK, Brown A, Green J (2009) Moderate alcohol intake and cancer incidence in women. J Natl Cancer Inst101:296-305.
3. Asakage T, Yokoyama A, Haneda T, Yamazaki M, Muto M, Yokoyama T, Kato H, Igaki H, Tsujinaka T, Kumagai Y, Yokoyama M, Omori T, Watanabe H (2007) Genetic polymorphisms of alcohol and aldehyde dehydrogenases, and drinking, smoking and diet in Japanese men with oral and pharyngeal squamous cell carcinoma. Carcinogenesis28:865-874.
4. Bergsland EK (2006) When does the presence of the target predict response to the targeted agent?J Clin Oncol24:213-216.
5. Boonyaphiphat P, Thongsuksai P, Sriplung H, Puttawibul P (2002) Lifestyle habits and genetic susceptibility and the risk of esophageal cancer in the Thai population. Cancer Lett186:193-199.
6. Brooks PJ, Enoch MA, Goldman D, Li TK, Yokoyama A (2009) The alcohol flushing response: an unrecognized risk factor for esophageal cancer from alcohol consumption. PLoS Med6:e50.
7. Chao YC, Wang LS, Hsieh TY, Chu CW, Chang FY, Chu HC (2000) Chinese alcoholic patients with esophageal cancer are genetically different from alcoholics with acute pancreatitis and liver cirrhosis. Am J Gastroenterol95:2958-2964.
8. Chen YJ, Chen C, Wu DC, Lee CH, Wu CI, Lee JM, Goan YG, Huang SP, Lin CC, Li TC, Chou YP, Wu MT (2006) Interactive effects of lifetime alcohol consumption and alcohol and aldehyde dehydrogenase polymorphisms on esophageal cancer risks. Int J Cancer119:2827-2831.
9. Crabb DW, Edenberg HJ, Bosron WF, Li TK (1989) Genotypes for aldehyde dehydrogenase deficiency and alcohol sensitivity. The inactive ALDH2(2) allele is dominant. J Clin Invest83:314-316.
10. Cui R, Kamatani Y, Takahashi A, Usami M, Hosono N, Kawaguchi T, Tsunoda T, Kamatani N, Kubo M, Nakamura Y, Matsuda K (2009) Functional variants in ADH1B and ALDH2 coupled with alcohol and smoking synergistically enhance esophageal cancer risk. Gastroenterology137:1768-1775.
11. Ding JH, Li SP, Cao HX, Wu JZ, Gao CM, Su P, Liu YT, Zhou JN, Chang J, Yao GH (2009) Polymorphisms of alcohol dehydrogenase-2 and aldehyde dehydrogenase-2 and esophageal cancer risk in Southeast Chinese males. World J Gastroenterol15:2395-2400.
12. Guo YM, Wang Q, Liu YZ, Chen HM, Qi Z, Guo QH (2008) Genetic polymorphisms in cytochrome P4502E1, alcohol and aldehyde dehydrogenases and the risk of esophageal squamous cell carcinoma in Gansu Chinese males. World J Gastroenterol14:1444-1449.
13. Hashibe M, Boffetta P, Zaridze D, Shangina O, Szeszenia-Dabrowska N, Mates D, Janout V, Fabianova E, Bencko V, Moullan N, Chabrier A, Hung R, Hall J, Canzian F, Brennan P (2006) Evidence for an important role of alcohol- and aldehyde-metabolizing genes in cancers of the upper aerodigestive tract. Cancer Epidemiol Biomarkers Prev15:696-703.
14. Hashibe M, McKay JD, Curado MP, Oliveira JC, Koifman S, Koifman R, Zaridze D, Shangina O, Wunsch-Filho V, Eluf-Neto J, Levi JE, Matos E, Lagiou P, Lagiou A, Benhamou S, Bouchardy C, Szeszenia-Dabrowska N, Menezes A, Dall'Agnol MM, Merletti F, Richiardi L, Fernandez L, Lence J, Talamini R, Barzan L, Mates D, Mates IN, Kjaerheim K, Macfarlane GJ, Macfarlane TV, Simonato L, Canova C, Holcatova I, Agudo A, Castellsague X, Lowry R, Janout V, Kollarova H, Conway DI, McKinney PA, Znaor A, Fabianova E, Bencko V, Lissowska J, Chabrier A, Hung RJ, Gaborieau V, Boffetta P, Brennan P (2008) Multiple ADH genes are associated with upper aerodigestive cancers. Nat Genet40:707-709.
15. Hiraki A, Matsuo K, Wakai K, Suzuki T, Hasegawa Y, Tajima K (2007) Gene-gene and gene-environment interactions between alcohol drinking habit and polymorphisms in alcohol-metabolizing enzyme genes and the risk of head and neck cancer in Japan. Cancer Sci98:1087-1091.
16. Hori H, Kawano T, Endo M, Yuasa Y (1997) Genetic polymorphisms of tobacco- and alcohol-related metabolizing enzymes and human esophageal squamous cell carcinoma susceptibility. J Clin Gastroenterol25:568-575.
17. Lagiou P, Georgila C, Minaki P, Ahrens W, Pohlabeln H, Benhamou S, Bouchardy C, Slamova A, Schejbalova M, Merletti F, Richiardi L, Kjaerheim K, Agudo A, Castellsague X, Macfarlane TV, Macfarlane GJ, Talamini R, Barzan L, Canova C, Simonato L, Lowry R, Conway DI, McKinney PA, Znaor A, McCartan BE, Healy C, Nelis M, Metspalu A, Marron M, Hashibe M, Brennan PJ (2009) Alcohol-related cancers and genetic susceptibility in Europe: the ARCAGE project: study samples and data collection. Eur J Cancer Prev18:76-84.
18. Lee CH, Lee JM, Wu DC, Goan YG, Chou SH, Wu IC, Kao EL, Chan TF, Huang MC, Chen PS, Lee CY, Huang CT, Huang HL, Hu CY, Hung YH, Wu MT (2008) Carcinogenetic impact of ADH1B and ALDH2 genes on squamous cell carcinoma risk of the esophagus with regard to the consumption of alcohol, tobacco and betel quid. Int J Cancer122:1347-1356.
19. Lee CH, Wu DC, Wu IC, Goan YG, Lee JM, Chou SH, Chan TF, Huang HL, Hung YH, Huang MC, Lai TC, Wang TN, Lan CC, Tsai S, Lin WY, Wu MT (2009) Genetic modulation of ADH1B and ALDH2 polymorphisms with regard to alcohol and tobacco consumption for younger aged esophageal squamous cell carcinoma diagnosis. Int J Cancer125:1134-1142.
20. Li H, Gu S, Cai X, Speed WC, Pakstis AJ, Golub EI, Kidd JR, Kidd KK (2008) Ethnic related selection for an ADH Class I variant within East Asia. PLoS ONE3:e1881.
21. Li H, Mukherjee N, Soundararajan U, Tarnok Z, Barta C, Khaliq S, Mohyuddin A, Kajuna SL, Mehdi SQ, Kidd JR, Kidd KK (2007) Geographically separate increases in the frequency of the derived ADH1B*47His allele in eastern and western Asia. Am J Hum Genet81:842-846.
22. Lohmueller KE, Pearce CL, Pike M, Lander ES, Hirschhorn JN (2003) Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease. Nat Genet33:177-182.
23. Luczak SE, Glatt SJ, Wall TL (2006) Meta-analyses of ALDH2 and ADH1B with alcohol dependence in Asians. Psychol Bull132:607-621.
24. Macgregor S, Lind PA, Bucholz KK, Hansell NK, Madden PA, Richter MM, Montgomery GW, Martin NG, Heath AC, Whitfield JB (2009) Associations of ADH and ALDH2 gene variation with self report alcohol reactions, consumption and dependence: an integrated analysis. Hum Mol Genet18:580-593.
25. Oze I, Matsuo K, Suzuki T, Kawase T, Watanabe M, Hiraki A, Ito H, Hosono S, Ozawa T, Hatooka S, Yatabe Y, Hasegawa Y, Shinoda M, Kiura K, Tajima K, Tanimoto M, Tanaka H (2009) Impact of multiple alcohol dehydrogenase gene polymorphisms on risk of upper aerodigestive tract cancers in a Japanese population. Cancer Epidemiol Biomarkers Prev18:3097-3102.
26. Risch A, Ramroth H, Raedts V, Rajaee-Behbahani N, Schmezer P, Bartsch H, Becher H, Dietz A (2003) Laryngeal cancer risk in Caucasians is associated with alcohol and tobacco consumption but not modified by genetic polymorphisms in class I alcohol dehydrogenases ADH1B and ADH1C, and glutathione-S-transferases GSTM1 and GSTT1. Pharmacogenetics13:225-230.
27. Sam SS, Thomas V, Reddy KS, Surianarayanan G, Chandrasekaran A (2010) Gene-environment interactions associated with CYP1A1 MspI and GST polymorphisms and the risk of upper aerodigestive tract cancers in an Indian population. J Cancer Res Clin Oncol136:945-951.
28. Smith M (1986) Genetics of human alcohol and aldehyde dehydrogenases. Adv Hum Genet15:249-290.
29. Solomon PR, Selvam GS, Shanmugam G (2008) Polymorphism in ADH and MTHFR genes in oral squamous cell carcinoma of Indians. Oral Dis14:633-639.
30. Soya SS, Vinod T, Reddy KS, Gopalakrishnan S, Adithan C (2007) Genetic polymorphisms of glutathione-S-transferase genes (GSTM1, GSTT1 and GSTP1) and upper aerodigestive tract cancer risk among smokers, tobacco chewers and alcoholics in an Indian population. Eur J Cancer43:2698-2706.
31. Thomasson HR, Edenberg HJ, Crabb DW, Mai XL, Jerome RE, Li TK, Wang SP, Lin YT, Lu RB, Yin SJ (1991) Alcohol and aldehyde dehydrogenase genotypes and alcoholism in Chinese men. Am J Hum Genet48:677-681.
32. Wall TL (2005) Genetic associations of alcohol and aldehyde dehydrogenase with alcohol dependence and their mechanisms of action. Ther Drug Monit27:700-703.
33. Wu CF, Wu DC, Hsu HK, Kao EL, Lee JM, Lin CC, Wu MT (2005) Relationship between genetic polymorphisms of alcohol and aldehyde dehydrogenases and esophageal squamous cell carcinoma risk in males. World J Gastroenterol11:5103-5108.
34. Yang CX, Matsuo K, Ito H, Hirose K, Wakai K, Saito T, Shinoda M, Hatooka S, Mizutani K, Tajima K (2005) Esophageal cancer risk by ALDH2 and ADH2 polymorphisms and alcohol consumption: exploration of gene-environment and gene-gene interactions. Asian Pac J Cancer Prev6:256-262.
35. Yang SJ, Wang HY, Li XQ, Du HZ, Zheng CJ, Chen HG, Mu XY, Yang CX (2007) Genetic polymorphisms of ADH2 and ALDH2 association with esophageal cancer risk in southwest China. World J Gastroenterol13:5760-5764.
36. Zhang GH, Mai RQ, Huang B (2010) Meta-analysis of ADH1B and ALDH2 polymorphisms and esophageal cancer risk in China. World J Gastroenterol16:6020-6025.