Polymorphisms of alcohol dehydrogenase-2 anal aldehyde dehydrogenase-2 and esophageal cancer risk in Southeast Chinese males

World Journal of Gastroenterology

Volumn 15, Issue 19, 2009, Pages 2395-2400

  Ding, Jian Hua ^a   Li, Su Ping ^a   Cao, Hai Xia ^a   Wu, Jian Zhong ^a   Gao, Chang Ming ^a   Su, Ping ^a   Liu, Yan Ting ^a   Zhou, Jian Nong ^a   Chang, Jun ^b   Yao, Gen Hong ^b  

^a JIANGSU CANCER HOSPITAL   (China)

^b Taixing Center for Disease Prevention and Control   (China)

Author keywords

Alcohol dehydrogenase 2; Alcohol drinking; Aldehyde dehydrogenase 2; Esophageal cancer; Gene polymorphisms

Indexed keywords

ALCOHOL DEHYDROGENASE; ALCOHOL DEHYDROGENASE 2; ALDEHYDE DEHYDROGENASE ISOENZYME 2; UNCLASSIFIED DRUG;

ADULT; AGED; ALCOHOL CONSUMPTION; ALLELE; ARTICLE; CANCER RISK; CANCER SUSCEPTIBILITY; CHINESE; CONTROLLED STUDY; DENATURING HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; DNA POLYMORPHISM; ESOPHAGUS CANCER; GENE FREQUENCY; GENE FUNCTION; GENE IDENTIFICATION; GENE INTERACTION; GENETIC ASSOCIATION; GENOTYPE; HETEROZYGOSITY; HIGH RISK POPULATION; HUMAN; MAJOR CLINICAL STUDY; MALE; POLYMERASE CHAIN REACTION; RISK ASSESSMENT;

EID: 67651247830     PISSN: 10079327     EISSN: None     Source Type: Journal    
DOI: 10.3748/wjg.15.2395     Document Type: Article

References (20)

1. Gemma S, Vichi S, Testai E. Individual susceptibility and alcohol effects:biochemical and genetic aspects. Ann Ist Super Sanita 2006; 42: 8-16
2. Matsuo K, Hamajima N, Shinoda M, Hatooka S, Inoue M, Takezaki T, Tajima K. Gene-environment interaction between an aldehyde dehydrogenase-2 (ALDH2) polymorphism and alcohol consumption for the risk of esophageal cancer. Carcinogenesis 2001; 22: 913-916
3. Bosron WF, Li TK. Genetic polymorphism of human liver alcohol and aldehyde dehydrogenases, and their relationship to alcohol metabolism and alcoholism. Hepatology 1986; 6: 502-510
4. Bosron WF, Lumeng L, Li TK. Genetic polymorphism of enzymes of alcohol metabolism and susceptibility to alcoholic liver disease. Mol Aspects Med 1988; 10: 147-158
5. Enomoto N, Takase S, Yasuhara M, Takada A. Acetaldehyde metabolism in different aldehyde dehydrogenase-2 genotypes. Alcohol Clin Exp Res 1991; 15: 141-144
6. Ding JH, Li SP, Gao CM, Zhou J N, Su P, Wu JZ, Zhang Y, Liu YT, Zhou XF, Ding BG, Wang RH. On population based case-control study of upper digestive tract cancer. Zhongguo Gonggong Weisheng 2001; 17: 319-320
7. Ding JH, Wu JZ, Li SP, Gao CM, Zhou JN, Su P, Liu YT, Zhou XF, Ding BG, Wang RH. Polymorphisms of aldehyde Dehydrogenase-2 genotypes and alcohol consumption for the susceptibility of the liver cancer, stomach cancer and esophageal cancer. Zhongguo Zhongliu 2002; 11: 450-452
8. Tan SK, Qiu XQ, Yu HP, Zeng XY, Zhao YN, Hu L. [Evaluation of the risk of clonorchiasis inducing primary hepatocellular carcinoma] Zhonghua Gan Zang Bing Za Zhi 2008; 16: 114-116
9. Ding J, Li S, Wu J, Gao C, Zhou J, Cao H, Su PS, Liu Y, Zhou X, Chang J. Alcohol dehydrogenase-2 and aldehyde dehydrogenase-2 genotypes, alcohol drinking and the risk of primary hepatocellular carcinoma in a Chinese population. Asian Pac J Cancer Prev 2008; 9: 31-35
10. Chao YC, Wang LS, Hsieh TY, Chu CW, Chang FY, Chu HC. Chinese alcoholic patients with esophageal cancer are genetically different from alcoholics with acute pancreatitis and liver cirrhosis. Am J Gastroenterol 2000; 95: 2958-2964
11. Wu CF, Wu DC, Hsu HK, Kao EL, Lee JM, Lin CC, Wu MT. Relationship between genetic polymorphisms of alcohol and aldehyde dehydrogenases and esophageal squamous cell carcinoma risk in males. World J Gastroenterol 2005; 11: 5103-5108
12. Yang CX, Matsuo K, Ito H, Hirose K, Wakai K, Saito T, Shinoda M, Hatooka S, Mizutani K, Tajima K. Esophageal cancer risk by ALDH2 and ADH2 polymorphisms and alcohol consumption: exploration of gene-environment and gene-gene interactions. Asian Pac J Cancer Prev 2005; 6: 256-262
13. Chen YJ, Chen C, Wu DC, Lee CH, Wu CI, Lee JM, Goan YG, Huang SP, Lin CC, Li TC, Chou YP, Wu MT. Interactive effects of lifetime alcohol consumption and alcohol and aldehyde dehydrogenase polymorphisms on esophageal cancer risks. Int J Cancer 2006; 119: 2827-2831
14. Yokoyama A, Muramatsu T, Omori T, Yokoyama T, Matsushita S, Higuchi S, Maruyama K, Ishii H. Alcohol and aldehyde dehydrogenase gene polymorphisms and oropharyngolaryngeal, esophageal and stomach cancers in Japanese alcoholics. Carcinogenesis 2001; 22: 433-439
15. Guo YM, Wang Q, Liu YZ, Chen HM, Qi Z, Guo QH. Genetic polymorphisms in cytochrome P4502E1, alcohol and aldehyde dehydrogenases and the risk of esophageal squamous cell carcinoma in Gansu Chinese males. World J Gastroenterol 2008; 14: 1444-1449
16. Yang SJ, Wang HY, Li XQ, Du HZ, Zheng CJ, Chen HG, Mu XY, Yang CX. Genetic polymorphisms of ADH2 and ALDH2 association with esophageal cancer risk in southwest China. World J Gastroenterol 2007; 13: 5760-5764
17. Boonyaphiphat P, Thongsuksai P, Sriplung H, Puttawibul P. Lifestyle habits and genetic susceptibility and the risk of esophageal cancer in the Thai population. Cancer Lett 2002; 186: 193-199
18. Yokoyama A, Kato H, Yokoyama T, Tsujinaka T, Muto M, Omori T, Haneda T, Kumagai Y, Igaki H, Yokoyama M, Watanabe H, Fukuda H, Yoshimizu H. Genetic polymorphisms of alcohol and aldehyde dehydrogenases and glutathione S-transferase M1 and drinking, smoking, and diet in Japanese men with esophageal squamous cell carcinoma. Carcinogenesis 2002; 23: 1851-1859
19. Mizoi Y, Yamamoto K, Ueno Y, Fukunaga T, Harada S. Involvement of genetic polymorphism of alcohol and aldehyde dehydrogenases in individual variation of alcohol metabolism. Alcohol Alcohol 1994; 29: 707-710
20. Yoshihara E, Ameno K, Nakamura K, Ameno M, Itoh S, Ijiri I, Iwahashi K. The effects of the ALDH2*1/2, CYP2E1 C1/C2 and C/D genotypes on blood ethanol elimination. Drug Chem Toxicol 2000; 23: 371-379