A high HIF-1α expression genotype is associated with poor prognosis of upper aerodigestive tract carcinoma patients

Oral Oncology

Volumn 48, Issue 2, 2012, Pages 130-135

  Fraga, Carlos Alberto De Carvalho ^a   De Oliveira, Marcos Vinícius MacEdo ^a   De Oliveira, Érica Silva ^a   Barros, Lucas Oliveira ^a   Santos, Francis Balduino Guimarães ^a   Gomez, Ricardo Santiago ^b   De Paula, Alfredo Maurício Batista ^a   Guimarães, André Luiz Sena ^a  

^a STATE UNIVERSITY OF MONTES CLAROS   (Brazil)

^b FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

Author keywords

Angiogenesis; HIF; Hypoxia; Metastasis; Polymorphism; Upper aerodigestive tract cancer; VEGFR1

Indexed keywords

ANGIOGENIC FACTOR; GELATINASE B; HYPOXIA INDUCIBLE FACTOR 1ALPHA; VASCULOTROPIN RECEPTOR 1; VASCULOTROPIN RECEPTOR 2;

ARTICLE; CANCER PATIENT; CANCER PROGNOSIS; CANCER SURVIVAL; CANCER TISSUE; CONTROLLED STUDY; GENETIC POLYMORPHISM; GENOTYPE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LARYNX CARCINOMA; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MOUTH CARCINOMA; PHARYNX CARCINOMA; PRIORITY JOURNAL; PROPORTIONAL HAZARDS MODEL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM;

ANTIGENS, CD; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; LYMPHATIC METASTASIS; MATRIX METALLOPROTEINASE 9; OTORHINOLARYNGOLOGIC NEOPLASMS; POLYMORPHISM, GENETIC; PROGNOSIS; RECEPTORS, CELL SURFACE; RETROSPECTIVE STUDIES; SURVIVAL ANALYSIS; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-1; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-2;

EID: 84856330599     PISSN: 13688375     EISSN: 18790593     Source Type: Journal    
DOI: 10.1016/j.oraloncology.2011.08.023     Document Type: Article

References (40)

1. M.P. Curado, and M. Hashibe Recent changes in the epidemiology of head and neck cancer Curr Opin Oncol 21 3 2009 194 200
2. A. Argiris, M.V. Karamouzis, D. Raben, and R.L. Ferris Head and neck cancer Lancet 371 9625 2008 1695 1709 (Pubitemid 351671886)
3. R.S. Gomez, F.J. Pimenta, A.L. Guimaraes, L.N. Souza, U.E. Salomao, and H.C. de Almeida Effect of bone marrow transplantation on the immunolocalization of p53, hMSH2, and hMLH1 proteins on oral mucosa Oral Dis 10 4 2004 207 211 (Pubitemid 38868572)
4. C. Scully, J.K. Field, and H. Tanzawa Genetic aberrations in oral or head and neck squamous cell carcinoma 2: chromosomal aberrations Oral Oncol 36 4 2000 311 327 (Pubitemid 30427251)
5. L.C. Farias, C.A. De Carvalho Fraga, M.V. DeOliveira, T.F. Silva, L. Marques-Silva, and P.R. Moreira Effect of age on the association between p16CDKN2A methylation and DNMT3B polymorphism in head and neck carcinoma and patient survival Int J Oncol 37 1 2010 167 176
6. C.C. Gomes, S.N. Drummond, A.L. Guimaraes, C.I. Andrade, R.A. Mesquita, and R.S. Gomez P21/WAF1 and cyclin D1 variants and oral squamous cell carcinoma J Oral Pathol Med 37 3 2008 151 156 (Pubitemid 351178410)
7. A.L. Guimaraes, A.R. deSa, J.M. Victoria, J.F. Correia-Silva, P.S. Pessoa, and M.G. Diniz Association of interleukin-1beta polymorphism with recurrent aphthous stomatitis in Brazilian individuals Oral Dis 12 6 2006 580 583 (Pubitemid 44624362)
8. A.L. Guimaraes, J.F. Correia-Silva, M.G. Diniz, G.M. Xavier, M.C. Horta, and R.S. Gomez Investigation of functional gene polymorphisms: IL-1B, IL-6 and TNFA in benign migratory glossitis in Brazilian individuals J Oral Pathol Med 36 9 2007 533 537 (Pubitemid 47393532)
9. A.L. Guimaraes, J.F. Correia-Silva, A.R. Sa, J.M. Victoria, M.G. Diniz, and F.O. Costa Investigation of functional gene polymorphisms IL-1beta, IL-6, IL-10 and TNF-alpha in individuals with recurrent aphthous stomatitis Arch Oral Biol 52 3 2007 268 272 (Pubitemid 46110825)
10. G.M. Xavier, A.R. deSa, A.L. Guimaraes, T.A. daSilva, and R.S. Gomez Investigation of functional gene polymorphisms interleukin-1beta, interleukin-6, interleukin-10 and tumor necrosis factor in individuals with oral lichen planus J Oral Pathol Med 36 8 2007 476 481 (Pubitemid 47222103)
11. J.M. Brown, and A.J. Giaccia The unique physiology of solid tumors: opportunities (and problems) for cancer therapy Cancer Res 58 7 1998 1408 1416 (Pubitemid 28193601)
12. Q.T. Le, N.C. Denko, and A.J. Giaccia Hypoxic gene expression and metastasis Cancer Metastasis Rev 23 3-4 2004 293 310 (Pubitemid 38881813)
13. Y. Luo, D.L. He, L. Ning, S.L. Shen, L. Li, and X. Li Hypoxia-inducible factor-1alpha induces the epithelial-mesenchymal transition of human prostatecancer cells Chin Med J (Engl) 119 9 2006 713 718 (Pubitemid 43796824)
14. G.L. Wang, B.H. Jiang, E.A. Rue, and G.L. Semenza Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension Proc Natl Acad Sci U S A 92 12 1995 5510 5514
15. C.H. Chau, M.G. Permenter, S.M. Steinberg, A.S. Retter, W.L. Dahut, and D.K. Price Polymorphism in the hypoxia-inducible factor 1alpha gene may confer susceptibility to androgen-independent prostate cancer Cancer Biol Ther 4 11 2005 1222 1225
16. X.S. Fu, E. Choi, G.J. Bubley, and S.P. Balk Identification of hypoxia-inducible factor-1alpha (HIF-1alpha) polymorphism as a mutation in prostate cancer that prevents normoxia-induced degradation Prostate 63 3 2005 215 221 (Pubitemid 40571055)
17. R.N. Kaplan, R.D. Riba, S. Zacharoulis, A.H. Bramley, L. Vincent, and C. Costa VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche Nature 438 7069 2005 820 827 (Pubitemid 41753060)
18. S.J. Kim, Z.N. Rabbani, M.W. Dewhirst, Z. Vujaskovic, R.T. Vollmer, and E.G. Schreiber Expression of HIF-1alpha, CA IX, VEGF, and MMP-9 in surgically resected non-small cell lung cancer Lung Cancer 49 3 2005 325 335 (Pubitemid 41139145)
19. M.K. Chen, H.L. Chiou, S.C. Su, T.T. Chung, H.C. Tseng, and H.T. Tsai The association between hypoxia inducible factor-1alpha gene polymorphisms and increased susceptibility to oral cancer Oral Oncol 45 12 2009 e222 e226
20. D. Liao, C. Corle, T.N. Seagroves, and R.S. Johnson Hypoxia-inducible factor-1alpha is a key regulator of metastasis in a transgenic model of cancer initiation and progression Cancer Res 67 2 2007 563 572 (Pubitemid 46192193)
21. E.K. Rofstad, B. Mathiesen, K. Henriksen, K. Kindem, and K. Galappathi The tumor bed effect: increased metastatic dissemination from hypoxia-induced up-regulation of metastasis-promoting gene products Cancer Res 65 6 2005 2387 2396 (Pubitemid 40490150)
22. G.L. Semenza Targeting HIF-1 for cancer therapy Nat Rev Cancer 3 10 2003 721 732 (Pubitemid 37328811)
23. A.M. De Paula, L.R. Souza, L.C. Farias, G.T. Correa, C.A. Fraga, and N.B. Eleuterio Analysis of 724 cases of primary head and neck squamous cell carcinoma (HNSCC) with a focus on young patients and p53 immunolocalization Oral Oncol 45 9 2009 777 782
24. L.H. Sobin TNM: evolution and relation to other prognostic factors Semin Surg Oncol 21 1 2003 3 7 (Pubitemid 37127467)
25. Q.T. Le, J. Harris, A.M. Magliocco, C.S. Kong, R. Diaz, and B. Shin Validation of lysyl oxidase as a prognostic marker for metastasis and survival in head and neck squamous cell carcinoma: Radiation Therapy Oncology Group trial 90-03 J Clin Oncol 27 26 2009 4281 4286
26. R.A. Cairns, and R.P. Hill Acute hypoxia enhances spontaneous lymph node metastasis in an orthotopic murine model of human cervical carcinoma Cancer Res 64 6 2004 2054 2061 (Pubitemid 38339453)
27. E.K. Rofstad, K. Galappathi, B. Mathiesen, and E.B. Ruud Fluctuating and diffusion-limited hypoxia in hypoxia-induced metastasis Clin Cancer Res 13 7 2007 1971 1978 (Pubitemid 46649862)
28. S. North, M. Moenner, and A. Bikfalvi Recent developments in the regulation of the angiogenic switch by cellular stress factors in tumors Cancer Lett 218 1 2005 1 14 (Pubitemid 40082696)
29. G.L. Semenza Hydroxylation of HIF-1: oxygen sensing at the molecular level Physiology (Bethesda) 19 2004 176 182 (Pubitemid 39481932)
30. A.G. Anastasiadis, M.A. Ghafar, L. Salomon, F. Vacherot, P. Benedit, and M.W. Chen Human hormone-refractory prostate cancers can harbor mutations in the O(2)-dependent degradation domain of hypoxia inducible factor-1alpha (HIF-1alpha) J Cancer Res Clin Oncol 128 7 2002 358 362 (Pubitemid 34824177)
31. P.H. Maxwell, C.W. Pugh, and P.J. Ratcliffe Activation of the HIF pathway in cancer Curr Opin Genet Dev 11 3 2001 293 299 (Pubitemid 32480296)
32. K. Tanimoto, K. Yoshiga, H. Eguchi, M. Kaneyasu, K. Ukon, and T. Kumazaki Hypoxia-inducible factor-1alpha polymorphisms associated with enhanced transactivation capacity, implying clinical significance Carcinogenesis 24 11 2003 1779 1783 (Pubitemid 37408141)
33. C. Trastour, E. Benizri, F. Ettore, A. Ramaioli, E. Chamorey, and J. Pouyssegur HIF-1alpha and CA IX staining in invasive breast carcinomas: prognosis and treatment outcome Int J Cancer 120 7 2007 1451 1458 (Pubitemid 46355379)
34. M.F. Munoz-Guerra, M.E. Fernandez-Contreras, A.L. Moreno, I.D. Martin, B. Herraez, and C. Gamallo Polymorphisms in the hypoxia inducible factor 1-alpha and the impact on the prognosis of early stages of oral cancer Ann Surg Oncol 16 8 2009 2351 2358
35. R.N. Kaplan, S. Rafii, and D. Lyden Preparing the "soil": the premetastatic niche Cancer Res 66 23 2006 11089 11093
36. Z. Karaca, F. Tanriverdi, G. Elbuken, I. Cakir, H. Donmez, and A. Selcuklu Comparison of primary octreotide-lar and surgical treatment in newly diagnosed patients with acromegaly Clin Endocrinol (Oxf) 2011
37. G. Marioni, F. Marino, L. Giacomelli, C. Staffieri, M.L. Mariuzzi, and E. Violino Endoglin expression is associated with poor oncologic outcome in oral and oropharyngeal carcinoma Acta Otolaryngol 126 6 2006 633 639 (Pubitemid 43995216)
38. E. Fonsatti, and M. Maio Highlights on endoglin (CD105): from basic findings towards clinical applications in human cancer J Transl Med 2 1 2004 18
39. P. Maroni, E. Matteucci, A. Luzzati, G. Perrucchini, P. Bendinelli, and M.A. Desiderio Nuclear co-localization and functional interaction of COX-2 and HIF-1alpha characterize bone metastasis of human breast carcinoma Breast Cancer Res Treat 2010
40. H. Shim, S.K. Lau, S. Devi, Y. Yoon, H.T. Cho, and Z. Liang Lower expression of CXCR4 in lymph node metastases than in primary breast cancers: potential regulation by ligand-dependent degradation and HIF-1alpha Biochem Biophys Res Commun 346 1 2006 252 258 (Pubitemid 43865990)