메뉴 건너뛰기




Volumn 39, Issue 2, 2012, Pages 295-303

Simplified quantification and whole-body distribution of [ 18F]FE-PE2I in nonhuman primates: Prediction for human studies

Author keywords

Dopamine transporter; Dosimetry; Noninvasive; Parkinson; PET; Quantification

Indexed keywords

FLUORODEOXYGLUCOSE F 18; N (3 IODO PROP 2 ENYL) 2BETA CARBOFLUOROETHOXY 3BETA (4' METHYLPHENYL)NORTROPANE F 18; RADIOPHARMACEUTICAL AGENT; UNCLASSIFIED DRUG;

EID: 84856315375     PISSN: 09698051     EISSN: 18729614     Source Type: Journal    
DOI: 10.1016/j.nucmedbio.2011.08.004     Document Type: Article
Times cited : (14)

References (42)
  • 1
    • 77957100232 scopus 로고    scopus 로고
    • Molecular imaging of the dopamine transporter
    • Varrone A, Halldin C Molecular imaging of the dopamine transporter. J Nucl Med 2010, 51:1331-1334.
    • (2010) J Nucl Med , vol.51 , pp. 1331-1334
    • Varrone, A.1    Halldin, C.2
  • 2
    • 0037012478 scopus 로고    scopus 로고
    • Dopamine transporter brain imaging to assess the effects of pramipexole vs levodopa on Parkinson disease progression
    • Dopamine transporter brain imaging to assess the effects of pramipexole vs levodopa on Parkinson disease progression. JAMA 2002, 287:1653-1661.
    • (2002) JAMA , vol.287 , pp. 1653-1661
  • 3
    • 7244225004 scopus 로고    scopus 로고
    • Impact of dopamine transporter SPECT using 123I-ioflupane on diagnosis and management of patients with clinically uncertain Parkinsonian syndromes
    • Catafau AM, Tolosa E Impact of dopamine transporter SPECT using 123I-ioflupane on diagnosis and management of patients with clinically uncertain Parkinsonian syndromes. Mov Disord 2004, 19:1175-1182.
    • (2004) Mov Disord , vol.19 , pp. 1175-1182
    • Catafau, A.M.1    Tolosa, E.2
  • 4
    • 60549091544 scopus 로고    scopus 로고
    • Multimodality imaging: an update on PET/CT technology
    • Mawlawi O, Townsend DW Multimodality imaging: an update on PET/CT technology. Eur J Nucl Med Mol Imaging 2009, 36(Suppl 1):S15-S29.
    • (2009) Eur J Nucl Med Mol Imaging , vol.36 , Issue.SUPPL. 1
    • Mawlawi, O.1    Townsend, D.W.2
  • 5
    • 66049155322 scopus 로고    scopus 로고
    • Hybrid imaging technology: from dreams and vision to clinical devices
    • Patton JA, Townsend DW, Hutton BF Hybrid imaging technology: from dreams and vision to clinical devices. Semin Nucl Med 2009, 39:247-263.
    • (2009) Semin Nucl Med , vol.39 , pp. 247-263
    • Patton, J.A.1    Townsend, D.W.2    Hutton, B.F.3
  • 6
    • 44849110925 scopus 로고    scopus 로고
    • Impact of image-space resolution modeling for studies with the high-resolution research tomograph
    • Sureau FC, Reader AJ, Comtat C, Leroy C, Ribeiro MJ, Buvat I, et al. Impact of image-space resolution modeling for studies with the high-resolution research tomograph. J Nucl Med 2008, 49:1000-1008.
    • (2008) J Nucl Med , vol.49 , pp. 1000-1008
    • Sureau, F.C.1    Reader, A.J.2    Comtat, C.3    Leroy, C.4    Ribeiro, M.J.5    Buvat, I.6
  • 7
    • 70350547987 scopus 로고    scopus 로고
    • Advancement in PET quantification using 3D-OP-OSEM point spread function reconstruction with the HRRT
    • Varrone A, Sjoholm N, Eriksson L, Gulyas B, Halldin C, Farde L Advancement in PET quantification using 3D-OP-OSEM point spread function reconstruction with the HRRT. Eur J Nucl Med Mol Imaging 2009, 36:1639-1650.
    • (2009) Eur J Nucl Med Mol Imaging , vol.36 , pp. 1639-1650
    • Varrone, A.1    Sjoholm, N.2    Eriksson, L.3    Gulyas, B.4    Halldin, C.5    Farde, L.6
  • 8
    • 67650736208 scopus 로고    scopus 로고
    • Olfactory dysfunction in pure autonomic failure: implications for the pathogenesis of Lewy body diseases
    • Goldstein DS, Sewell L. Olfactory dysfunction in pure autonomic failure: implications for the pathogenesis of Lewy body diseases. Parkinsonism Relat Disord 2009, 15:516-520.
    • (2009) Parkinsonism Relat Disord , vol.15 , pp. 516-520
    • Goldstein, D.S.1    Sewell, L.2
  • 9
    • 0025695511 scopus 로고
    • The nigrostriatal dopaminergic system assessed in vivo by positron emission tomography in healthy volunteer subjects and patients with Parkinson's disease
    • Leenders KL, Salmon EP, Tyrrell P, Perani D, Brooks DJ, Sager H, et al. The nigrostriatal dopaminergic system assessed in vivo by positron emission tomography in healthy volunteer subjects and patients with Parkinson's disease. Arch Neurol 1990, 47:1290-1298.
    • (1990) Arch Neurol , vol.47 , pp. 1290-1298
    • Leenders, K.L.1    Salmon, E.P.2    Tyrrell, P.3    Perani, D.4    Brooks, D.J.5    Sager, H.6
  • 10
    • 10344229443 scopus 로고    scopus 로고
    • Comparative nigrostriatal dopaminergic imaging with iodine-123-beta CIT-FP/SPECT and fluorine-18-FDOPA/PET
    • Ishikawa T, Dhawan V, Kazumata K, Chaly T, Mandel F, Neumeyer J, et al. Comparative nigrostriatal dopaminergic imaging with iodine-123-beta CIT-FP/SPECT and fluorine-18-FDOPA/PET. J Nucl Med 1996, 37:1760-1765.
    • (1996) J Nucl Med , vol.37 , pp. 1760-1765
    • Ishikawa, T.1    Dhawan, V.2    Kazumata, K.3    Chaly, T.4    Mandel, F.5    Neumeyer, J.6
  • 11
    • 0030744810 scopus 로고    scopus 로고
    • Nigrostriatal dopaminergic imaging with iodine-123-beta CIT-FP/SPECT and fluorine-18-FDOPA/PET
    • Tissingh G, Bergmans P, Winogrodzka A, Stoof JC, Wolters EC, Booij J, et al. Nigrostriatal dopaminergic imaging with iodine-123-beta CIT-FP/SPECT and fluorine-18-FDOPA/PET. J Nucl Med 1997, 38:1271-1272.
    • (1997) J Nucl Med , vol.38 , pp. 1271-1272
    • Tissingh, G.1    Bergmans, P.2    Winogrodzka, A.3    Stoof, J.C.4    Wolters, E.C.5    Booij, J.6
  • 12
    • 18844471416 scopus 로고    scopus 로고
    • In vivo positron emission tomographic evidence for compensatory changes in presynaptic dopaminergic nerve terminals in Parkinson's disease
    • Lee CS, Samii A, Sossi V, Ruth TJ, Schulzer M, Holden JE, et al. In vivo positron emission tomographic evidence for compensatory changes in presynaptic dopaminergic nerve terminals in Parkinson's disease. Ann Neurol 2000, 47:493-503.
    • (2000) Ann Neurol , vol.47 , pp. 493-503
    • Lee, C.S.1    Samii, A.2    Sossi, V.3    Ruth, T.J.4    Schulzer, M.5    Holden, J.E.6
  • 13
    • 79953236488 scopus 로고    scopus 로고
    • Synuclein modulation of monoamine transporters
    • Oaks AW, Sidhu A Synuclein modulation of monoamine transporters. FEBS Lett 2011, 585:1001-1006.
    • (2011) FEBS Lett , vol.585 , pp. 1001-1006
    • Oaks, A.W.1    Sidhu, A.2
  • 14
    • 0026637603 scopus 로고
    • Repeated reserpine administration reduces in vivo [18F]GBR 13119 binding to the dopamine uptake site
    • Kilbourn MR, Sherman PS, Pisani T Repeated reserpine administration reduces in vivo [18F]GBR 13119 binding to the dopamine uptake site. Eur J Pharmacol 1992, 216:109-112.
    • (1992) Eur J Pharmacol , vol.216 , pp. 109-112
    • Kilbourn, M.R.1    Sherman, P.S.2    Pisani, T.3
  • 15
    • 0030051113 scopus 로고    scopus 로고
    • Modulatory effect of agents active in the presynaptic dopaminergic system on the striatal dopamine transporter
    • Gordon I, Weizman R, Rehavi M Modulatory effect of agents active in the presynaptic dopaminergic system on the striatal dopamine transporter. Eur J Pharmacol 1996, 298:27-30.
    • (1996) Eur J Pharmacol , vol.298 , pp. 27-30
    • Gordon, I.1    Weizman, R.2    Rehavi, M.3
  • 16
    • 0034931817 scopus 로고    scopus 로고
    • Brain radioligands - state of the art and new trends
    • Halldin C, Gulyas B, Langer O, Farde L Brain radioligands - state of the art and new trends. Q J Nucl Med 2001, 45:139-152.
    • (2001) Q J Nucl Med , vol.45 , pp. 139-152
    • Halldin, C.1    Gulyas, B.2    Langer, O.3    Farde, L.4
  • 17
    • 0141447478 scopus 로고    scopus 로고
    • [(11)C]PE2I: a highly selective radioligand for PET examination of the dopamine transporter in monkey and human brain
    • Halldin C, Erixon-Lindroth N, Pauli S, Chou YH, Okubo Y, Karlsson P, et al. [(11)C]PE2I: a highly selective radioligand for PET examination of the dopamine transporter in monkey and human brain. Eur J Nucl Med Mol Imaging 2003, 30:1220-1230.
    • (2003) Eur J Nucl Med Mol Imaging , vol.30 , pp. 1220-1230
    • Halldin, C.1    Erixon-Lindroth, N.2    Pauli, S.3    Chou, Y.H.4    Okubo, Y.5    Karlsson, P.6
  • 18
    • 4344618164 scopus 로고    scopus 로고
    • Potential of [(18)F]beta-CFT-FE (2beta-carbomethoxy-3beta-(4-fluorophenyl)-8-(2-[(18)F]fluoroethyl)nortropane) as a dopamine transporter ligand: a PET study in the conscious monkey brain
    • Harada N, Ohba H, Fukumoto D, Kakiuchi T, Tsukada H. Potential of [(18)F]beta-CFT-FE (2beta-carbomethoxy-3beta-(4-fluorophenyl)-8-(2-[(18)F]fluoroethyl)nortropane) as a dopamine transporter ligand: a PET study in the conscious monkey brain. Synapse 2004, 54:37-45.
    • (2004) Synapse , vol.54 , pp. 37-45
    • Harada, N.1    Ohba, H.2    Fukumoto, D.3    Kakiuchi, T.4    Tsukada, H.5
  • 20
    • 67651097826 scopus 로고    scopus 로고
    • Synthesis, radiolabeling and preliminary in vivo evaluation of [18F]FE-PE2I, a new probe for the dopamine transporter
    • Schou M, Steiger C, Varrone A, Guilloteau D, Halldin C Synthesis, radiolabeling and preliminary in vivo evaluation of [18F]FE-PE2I, a new probe for the dopamine transporter. Bioorg Med Chem Lett 2009, 19:4843-4845.
    • (2009) Bioorg Med Chem Lett , vol.19 , pp. 4843-4845
    • Schou, M.1    Steiger, C.2    Varrone, A.3    Guilloteau, D.4    Halldin, C.5
  • 21
    • 70349123080 scopus 로고    scopus 로고
    • In vitro autoradiography and in vivo evaluation in cynomolgus monkey of [18F]FE-PE2I, a new dopamine transporter PET radioligand
    • Varrone A, Steiger C, Schou M, Takano A, Finnema SJ, Guilloteau D, et al. In vitro autoradiography and in vivo evaluation in cynomolgus monkey of [18F]FE-PE2I, a new dopamine transporter PET radioligand. Synapse 2009, 63:871-880.
    • (2009) Synapse , vol.63 , pp. 871-880
    • Varrone, A.1    Steiger, C.2    Schou, M.3    Takano, A.4    Finnema, S.J.5    Guilloteau, D.6
  • 22
    • 34247596015 scopus 로고    scopus 로고
    • Identification and regional distribution in rat brain of radiometabolites of the dopamine transporter PET radioligand [11C]PE2I
    • Shetty HU, Zoghbi SS, Liow JS, Ichise M, Hong J, Musachio JL, et al. Identification and regional distribution in rat brain of radiometabolites of the dopamine transporter PET radioligand [11C]PE2I. Eur J Nucl Med Mol Imaging 2007, 34:667-678.
    • (2007) Eur J Nucl Med Mol Imaging , vol.34 , pp. 667-678
    • Shetty, H.U.1    Zoghbi, S.S.2    Liow, J.S.3    Ichise, M.4    Hong, J.5    Musachio, J.L.6
  • 23
    • 79851498843 scopus 로고    scopus 로고
    • Kinetic analysis and quantification of the dopamine transporter in the nonhuman primate brain with 11C-PE2I and 18F-FE-PE2I
    • Varrone A, Toth M, Steiger C, Takano A, Guilloteau D, Ichise M, et al. Kinetic analysis and quantification of the dopamine transporter in the nonhuman primate brain with 11C-PE2I and 18F-FE-PE2I. J Nucl Med 2011, 52:132-139.
    • (2011) J Nucl Med , vol.52 , pp. 132-139
    • Varrone, A.1    Toth, M.2    Steiger, C.3    Takano, A.4    Guilloteau, D.5    Ichise, M.6
  • 25
    • 0030468875 scopus 로고    scopus 로고
    • Simplified reference tissue model for PET receptor studies
    • Lammertsma AA, Hume SP Simplified reference tissue model for PET receptor studies. Neuroimage 1996, 4:153-158.
    • (1996) Neuroimage , vol.4 , pp. 153-158
    • Lammertsma, A.A.1    Hume, S.P.2
  • 27
    • 0041335224 scopus 로고    scopus 로고
    • Linearized reference tissue parametric imaging methods: application to [11C]DASB positron emission tomography studies of the serotonin transporter in human brain
    • Ichise M, Liow JS, Lu JQ, Takano A, Model K, Toyama H, et al. Linearized reference tissue parametric imaging methods: application to [11C]DASB positron emission tomography studies of the serotonin transporter in human brain. J Cereb Blood Flow Metab 2003, 23:1096-1112.
    • (2003) J Cereb Blood Flow Metab , vol.23 , pp. 1096-1112
    • Ichise, M.1    Liow, J.S.2    Lu, J.Q.3    Takano, A.4    Model, K.5    Toyama, H.6
  • 28
    • 0002071621 scopus 로고    scopus 로고
    • Special report: the 1996 guide for the care and use of laboratory animals
    • Clark JD, Gebhart GF, Gonder JC, Keeling ME, Kohn DF Special report: the 1996 guide for the care and use of laboratory animals. Ilar J 1997, 38:41-48.
    • (1997) Ilar J , vol.38 , pp. 41-48
    • Clark, J.D.1    Gebhart, G.F.2    Gonder, J.C.3    Keeling, M.E.4    Kohn, D.F.5
  • 30
    • 0024448632 scopus 로고
    • Kinetic analysis of central [11C]raclopride binding to D2-dopamine receptors studied by PET - a comparison to the equilibrium analysis
    • Farde L, Eriksson L, Blomquist G, Halldin C Kinetic analysis of central [11C]raclopride binding to D2-dopamine receptors studied by PET - a comparison to the equilibrium analysis. J Cereb Blood Flow Metab 1989, 9:696-708.
    • (1989) J Cereb Blood Flow Metab , vol.9 , pp. 696-708
    • Farde, L.1    Eriksson, L.2    Blomquist, G.3    Halldin, C.4
  • 31
    • 61449155331 scopus 로고    scopus 로고
    • [18F]flumazenil binding to central benzodiazepine receptor studies by PET - quantitative analysis and comparisons with [11C]flumazenil
    • Odano I, Halldin C, Karlsson P, Varrone A, Airaksinen AJ, Krasikova RN, et al. [18F]flumazenil binding to central benzodiazepine receptor studies by PET - quantitative analysis and comparisons with [11C]flumazenil. Neuroimage 2009, 45:891-902.
    • (2009) Neuroimage , vol.45 , pp. 891-902
    • Odano, I.1    Halldin, C.2    Karlsson, P.3    Varrone, A.4    Airaksinen, A.J.5    Krasikova, R.N.6
  • 32
    • 0344096631 scopus 로고    scopus 로고
    • Delivery of radioligands for positron emission tomography (PET) in the central nervous system
    • Tsukada H Delivery of radioligands for positron emission tomography (PET) in the central nervous system. Adv Drug Deliv Rev 1999, 37:175-188.
    • (1999) Adv Drug Deliv Rev , vol.37 , pp. 175-188
    • Tsukada, H.1
  • 33
    • 0031833852 scopus 로고    scopus 로고
    • Estimation of absorbed dose for 2-[F-18]fluoro-2-deoxy-d-glucose using whole-body positron emission tomography and magnetic resonance imaging
    • Deloar HM, Fujiwara T, Shidahara M, Nakamura T, Watabe H, Narita Y, et al. Estimation of absorbed dose for 2-[F-18]fluoro-2-deoxy-d-glucose using whole-body positron emission tomography and magnetic resonance imaging. Eur J Nucl Med 1998, 25:565-574.
    • (1998) Eur J Nucl Med , vol.25 , pp. 565-574
    • Deloar, H.M.1    Fujiwara, T.2    Shidahara, M.3    Nakamura, T.4    Watabe, H.5    Narita, Y.6
  • 34
    • 0037487020 scopus 로고    scopus 로고
    • Dosimetry of the dopamine transporter radioligand 18F-FPCIT in human subjects
    • Robeson W, Dhawan V, Belakhlef A, Ma Y, Pillai V, Chaly T, et al. Dosimetry of the dopamine transporter radioligand 18F-FPCIT in human subjects. J Nucl Med 2003, 44:961-966.
    • (2003) J Nucl Med , vol.44 , pp. 961-966
    • Robeson, W.1    Dhawan, V.2    Belakhlef, A.3    Ma, Y.4    Pillai, V.5    Chaly, T.6
  • 36
    • 33847271750 scopus 로고    scopus 로고
    • Human biodistribution and radiation dosimetry of the tachykinin NK1 antagonist radioligand [18F]SPA-RQ: comparison of thin-slice, bisected, and 2-dimensional planar image analysis
    • Sprague DR, Chin FT, Liow JS, Fujita M, Burns HD, Hargreaves R, et al. Human biodistribution and radiation dosimetry of the tachykinin NK1 antagonist radioligand [18F]SPA-RQ: comparison of thin-slice, bisected, and 2-dimensional planar image analysis. J Nucl Med 2007, 48:100-107.
    • (2007) J Nucl Med , vol.48 , pp. 100-107
    • Sprague, D.R.1    Chin, F.T.2    Liow, J.S.3    Fujita, M.4    Burns, H.D.5    Hargreaves, R.6
  • 37
    • 0028285393 scopus 로고
    • Whole-body biodistribution, radiation absorbed dose and brain SPECT imaging with iodine-123-beta-CIT in healthy human subjects
    • Seibyl JP, Wallace E, Smith EO, Stabin M, Baldwin RM, Zoghbi S, et al. Whole-body biodistribution, radiation absorbed dose and brain SPECT imaging with iodine-123-beta-CIT in healthy human subjects. J Nucl Med 1994, 35:764-770.
    • (1994) J Nucl Med , vol.35 , pp. 764-770
    • Seibyl, J.P.1    Wallace, E.2    Smith, E.O.3    Stabin, M.4    Baldwin, R.M.5    Zoghbi, S.6
  • 38
  • 39
    • 0026361052 scopus 로고
    • ICRP, Radiological Protection in Biomedical Research. ICRP Publication 62. Ann. ICRP
    • ICRP, 1992. Radiological Protection in Biomedical Research. ICRP Publication 62. Ann. ICRP 22 (3).
    • (1992) , vol.22 , Issue.3
  • 40
    • 13944280450 scopus 로고    scopus 로고
    • Radiation protection 99: guidance on medical exposure in medical and biomedical research
    • In: NSaCP Directorate General Environment editor;
    • Radiation protection 99: guidance on medical exposure in medical and biomedical research. In: NSaCP Directorate General Environment editor; 1998.
    • (1998)
  • 42
    • 23044465598 scopus 로고    scopus 로고
    • Whole-body biodistribution, radiation dosimetry estimates for the PET norepinephrine transporter probe (S,S)-[18F]FMeNER-D2 in non-human primates
    • Seneca N, Andree B, Sjoholm N, Schou M, Pauli S, Mozley PD, et al. Whole-body biodistribution, radiation dosimetry estimates for the PET norepinephrine transporter probe (S,S)-[18F]FMeNER-D2 in non-human primates. Nucl Med Commun 2005, 26:695-700.
    • (2005) Nucl Med Commun , vol.26 , pp. 695-700
    • Seneca, N.1    Andree, B.2    Sjoholm, N.3    Schou, M.4    Pauli, S.5    Mozley, P.D.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.