Impact of dopamine transporter SPECT using 123I-Ioflupane on diagnosis and management of patients with clinically uncertain parkinsonian syndromes

Movement Disorders

Volumn 19, Issue 10, 2004, Pages 1175-1182

  Catafau, Ana M ^a,p   Tolosa, Eduardo ^b   Laloux, Patrice ^c   Vander Borght, Thierry ^c   Van Zandijcke, Michel ^d   De Geeter, Frank ^d   Destee, Alain ^e   Steinling, Marc ^e   Lacomblez, Lucette ^f   Habert, Marie Odile ^f   Weiller, Cornelius ^g   Clausen, Malte ^g   Bogdahn, Ulrich ^h   Haass, Anton ⁱ   Kirsch, Carl Martin ⁱ   Antonini, Angelo ^j   Benti, Riccardo ^j   Sorbi, Sandro ^k   Pupi, Alberto ^k   Cunha, Luís ^l   de Lima J P , Joao Pedroso ^l   Vallderiola, Frances ^b   Lomeña, Francisco ^b   Kulisevsky, Jaime ^a   Weeks, Robert ^m   Buxton Thomas, Muriel ^m   Gibb, William R G ⁿ   Kemp, Paul M ⁿ   Asenbaum, Susanne ^o   Dudczak, Robert ^o   more..

^a HOSPITAL DE LA SANTA CREU I SANT PAU   (Spain)

^b HOSPITAL CLÍNIC   (Spain)

^c University Hospital UCL   (Belgium)

^d General Hospital St Jan   (Belgium)

^e LILLE UNIVERSITY HOSPITAL   (France)

^f PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^g UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^h UNIVERSITY OF REGENSBURG   (Germany)

ⁱ SAARLAND UNIVERSITY   (Germany)

^j FONDAZIONE IRCCS CA GRANDA OSPEDALE MAGGIORE POLICLINICO   (Italy)

^k UNIVERSITY OF FLORENCE   (Italy)

^l CENTRO HOSPITALAR E UNIVERSITÁRIO DE COIMBRA   (Portugal)

^m KING S COLLEGE HOSPITAL   (United Kingdom)

ⁿ SOUTHAMPTON GENERAL HOSPITAL   (United Kingdom)

^o UNIVERSITY OF VIENNA   (Austria)

^p GLAXOSMITHKLINE   (Spain)

more..

Author keywords

123I Ioflupane; Dopamine transporter; Parkinsonism; SPECT

Indexed keywords

DOPAMINE TRANSPORTER; IOFLUPANE; IOFLUPANE I 123; LEVODOPA; RADIOPHARMACEUTICAL AGENT; UNCLASSIFIED DRUG;

ABDOMINAL PAIN; AGED; ARTICLE; CELL LOSS; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIAGNOSTIC IMAGING; DIARRHEA; DIZZINESS; DOPAMINERGIC NERVE CELL; EMOTIONAL DISORDER; EUPHORIA; FEMALE; HEADACHE; HUMAN; IMAGE ANALYSIS; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; NIGRONEOSTRIATAL SYSTEM; PARESTHESIA; PARKINSONISM; PATIENT CARE; PRESYNAPTIC NERVE; PRIORITY JOURNAL; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; STRIATONIGRAL DEGENERATION;

AGED; DOPAMINE PLASMA MEMBRANE TRANSPORT PROTEINS; FEMALE; HUMANS; IODINE RADIOISOTOPES; MALE; MEMBRANE GLYCOPROTEINS; MEMBRANE TRANSPORT PROTEINS; NERVE TISSUE PROTEINS; PARKINSONIAN DISORDERS; RADIOPHARMACEUTICALS; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON; TROPANES;

EID: 7244225004     PISSN: 08853185     EISSN: None     Source Type: Journal    
DOI: 10.1002/mds.20112     Document Type: Article

References (18)

1. 18F-dopa PET study. Neurology 1992;42:1554-1560.
2. Cohen O, Pullman S, Jurewicz E, Watner D, Louis ED. Rest tremor in patients with Essential Tremor, prevalence, clinical correlates and electrophysiology characteristics. Arch Neurol 2003; 60:405-410.
3. Hughes AJ, Daniel SE, Lees AJ. Improved accuracy of clinical diagnosis of Lewy body Parkinson's disease. Neurology 2001;57: 1497-1499.
4. Rajput AH, Rozdilsky B, Rajput A. Accuracy of clinical diagnosis in parkinsonism: a prospective study. Can J Neurol Sci 1991;18: 275-278.
5. Hughes AJ, Daniel SE, Kilford L, Lees AJ. Accuracy of clinical diagnosis of idiopathic Parkinson's disease: a clinico-pathological study of 100 cases. J Neurol Neurosurg Psychiatry 1992;55:181-184.
6. Quinn N. Parkinsonism: recognition and differential diagnosis. BMJ 1995;310:447-452.
7. Meara J, Bhowmick BK, Hobson P. Accuracy of diagnosis in patients with presumed Parkinson's disease. Age Ageing 1999;28: 99-102.
8. Kaufman MJ, Madras BK. Severe depletion of cocaine recognition sites associated with the dopamine transporter in Parkinson's-diseased striatum. Synapse 1991;9:43-49.
9. Niznik HB, Fogel EF, Fassos FF, Seeman P. The dopamine transporter is absent in parkinsonian putamen and reduced in caudate nucleus. J Neurochem 1991;56:192-198.
10. Neumeyer JL, Wang S, Gao Y, et al. N-omega-fluoroalkyl analogues of (1 R)-2 beta-carbomethoxy-3 beta-(4-iodophenyl)-tropane (beta-CIT): radiotracers for positron emission tomography and single photon emission computed tomography imaging of dopamine transporters. J Med Chem 1994;37:558-561.
11. Booij J, Andringa G, Rijks LJ, et al. 123I-FP-CIT binds to the dopamine transporter as assessed by biodistribution studies in rats and SPECT studies in MPTP-lesioned monkeys. Synapse 1997;27: 183-190.
12. 123I]FPCIT SPECT. J Nucl Med 1999;40:753-761.
13. 123I-FP-CIT study group. Mov Disord 2000;15:503-510.
14. 123I-FP-CIT SPECT in differentiating patients with presynaptic parkinsonism from those with other forms of parkinsonism. Eur J Nucl Med 2001;28:266-272.
15. Striatal phantom for SPECT, PET and MRI. Radiology Support Devices Inc., 1904 E. Dominguez St., Long Beach, CA 90810, USA.
16. Lokkegaard A, Werdelin LM, Friberg L. Clinical impact of diagnostic SPET investigations with a dopamine re-uptake ligand. Eur J Nucl Med 2002;29:1623-1629.
17. Jankovic J, Rajput AH, McDermott MP, Perl DP, for the Parkinson Study Group. The evolution of diagnosis in early Parkinson Disease. Arch Neurol 2000;57:369-372.
18. Larsen JP, Dupont E, Tandberg E. Clinical diagnosis of Parkinson's disease. Proposal of diagnostic subgroups classified at different levels of confidence. Acta Neurol Scand 1994;89:242-251.