Palmitoylation and trafficking of GAD65 are impaired in a cellular model of Huntington's disease

Biochemical Journal

Volumn 442, Issue 1, 2012, Pages 39-48

  Rush, Daniel B ^a   Leon, Rebecca T ^a   Mccollum, Mark H ^a   Treu, Ryan W ^a   Wei, Jianning ^a  

^a FLORIDA ATLANTIC UNIVERSITY   (United States)

Author keywords

Axonal transport; Glutamic acid decarboxylase 65 (GAD65); Huntingtin interacting protein 14 (HIP14); Polyglutamine repeat; Protein aggregate; Protein palmitoylation

Indexed keywords

4 AMINOBUTYRIC ACID; GLUTAMATE DECARBOXYLASE 65; GLUTAMATE DECARBOXYLASE 67; HUNTINGTIN; HUNTINGTIN INTERACTING PROTEIN 14; MUTANT PROTEIN; RAB PROTEIN; RAB5 PROTEIN; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL MIGRATION; CELL VACUOLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOSOL; ENDOPLASMIC RETICULUM; GENE OVEREXPRESSION; GOLGI COMPLEX; HUNTINGTON CHOREA; IN VIVO STUDY; MOUSE; NERVE CELL CULTURE; NEUROTRANSMISSION; NONHUMAN; PALMITOYLATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INTERACTION; SYNAPSE;

ACYLTRANSFERASES; ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; CELL LINE, TUMOR; ENDOPLASMIC RETICULUM; GLUTAMATE DECARBOXYLASE; HUMANS; HUNTINGTON DISEASE; LIPOYLATION; MICE; MICE, TRANSGENIC; NERVE TISSUE PROTEINS; NEURONS; NUCLEAR PROTEINS; PROTEIN TRANSPORT;

EID: 84856297905     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20110679     Document Type: Article

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