Epidermal growth factor receptor downregulation by small heterodimeric binding proteins

Protein Engineering, Design and Selection

Volumn 25, Issue 2, 2012, Pages 47-57

  Hackel, Benjamin J ^a   Neil, Jason R ^a   White, Forest M ^a,b   Wittrup, K Dane ^a,b  

^a Massachusetts Institute of Technology Cambridge   (United States)

^b KOCH INSTITUTE FOR INTEGRATIVE CANCER RESEARCH   (United States)

Author keywords

downregulation; EGFR; Fn3; heterodimers; yeast display

Indexed keywords

DOWN-REGULATION; EGFR; FN3; HETERODIMERS; YEAST DISPLAY;

MONOCLONAL ANTIBODIES;

PEPTIDES;

BINDING PROTEIN; CETUXIMAB; EPIDERMAL GROWTH FACTOR RECEPTOR; EPITOPE; FIBRONECTIN; HETERODIMER; HOMODIMER; MONOCLONAL ANTIBODY;

ARTICLE; AUTOPHOSPHORYLATION; CELL MIGRATION; CELL PROLIFERATION; CELL TYPE; DOWN REGULATION; HUMAN; HUMAN CELL; MOLECULAR WEIGHT; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN ENGINEERING;

AMINO ACID SEQUENCE; ANIMALS; BINDING, COMPETITIVE; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; CHO CELLS; CRICETINAE; CRICETULUS; DOWN-REGULATION; EPITOPES; FIBRONECTINS; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MOLECULAR WEIGHT; PEPTIDE LIBRARY; PEPTIDES; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN ENGINEERING; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECOMBINANT PROTEINS; SACCHAROMYCES CEREVISIAE;

EID: 84856295686     PISSN: 17410126     EISSN: 17410134     Source Type: Journal    
DOI: 10.1093/protein/gzr056     Document Type: Article

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