Haematological and biochemical toxicity induced by methanol in rats: Ameliorative effects of Opuntia vulgaris fruit extract

Human and Experimental Toxicology

Volumn 30, Issue 12, 2011, Pages 1963-1971

  Saoudi, Mongi ^a   Jebahi, Samira ^a   Jamoussi, Kamel ^b   Salah, Ghada Ben ^c   Kallel, Choumous ^d   El Fek, Abdelfattah ^a  

^a University of Sfax   (Tunisia)

^b HABIB BOURGUIBA HOSPITAL   (Tunisia)

^c UNIVERSITY OF SFAX   (Tunisia)

^d HEDI CHAKER HOSPITAL   (Tunisia)

Author keywords

Antioxidative enzymes; Haematological profile; Lipid peroxidation; Methanol; Modulatory role; Opuntia vulgaris

Indexed keywords

CATALASE; CHOLESTEROL; GLUCOSE; GLUTATHIONE PEROXIDASE; HEMOGLOBIN; METHANOL; OPUNTIA EXTRACT; OPUNTIA VULGARIS EXTRACT; SUPEROXIDE DISMUTASE; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIOXIDANT ACTIVITY; ARTICLE; BIOCHEMISTRY; BLOOD TOXICITY; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; ENZYME ACTIVITY; ERYTHROCYTE; FRUIT; GLUCOSE BLOOD LEVEL; HEMATOCRIT; HISTOPATHOLOGY; LIPID PEROXIDATION; MALE; MEDICINAL PLANT; NONHUMAN; OPUNTIA; OPUNTIA VULGARIS; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RAT; SPLEEN; TRIACYLGLYCEROL BLOOD LEVEL;

OPUNTIA; RATTUS;

EID: 84856275522     PISSN: 09603271     EISSN: 14770903     Source Type: Journal    
DOI: 10.1177/0960327111403175     Document Type: Article

References (45)

1. Plaziac C, Lachapelle P, and Casanova C. Effects of methanol on the retinal function of juvenile rats. NeuroToxicology 2003; 24: 255-260. (Pubitemid 36288104)
2. McKellar MJ, Hidajat RR, and Elder MJ. Acute ocular methanol toxicity: clinical and electrophysiological features. Aust N Z J Ophthalmol 1997; 25: 225-230. (Pubitemid 27376634)
3. Seme MT, Summerfelt P, Henry MM, Neitz J, and Eells JT. Formate-induced inhibition of photoreceptor function in methanol intoxication. J Pharmacol Exp Ther 1999; 289: 361-370. (Pubitemid 29156050)
4. Medinsky MA, Dorman DC, Bond JA, Moss OR, Janszen DB, and Everitt JI. Pharmacokinetics of methanol and formate in female cynomolgus monkeys exposed to methanol vapors. Res Rep Health Eff Inst 1997; 77: 322-327.
5. Kuteifan K, Oesterle H, Tajahmady T, Gutbub AM, and Laplatte G. Necrosis and haemorrhage of the putamen in methanol poisoning shown on MRI. Neuroradiology 1998; 40: 158-160. (Pubitemid 28438825)
6. Brahmi N, Blel Y, Abidi N, et al. Methanol poisoning in Tunisia: report of 16 cases. Clin Toxicol 2007; 45: 717-720. (Pubitemid 47394416)
7. Hantson P, Wallemacq P, Brau M, Vanbinst R, Haufroid V, andMahieu P. Two cases of acute methanol poisoning partially treated by oral 4-methylpyrazole. Intensive Care Med 1999; 25: 528-531. (Pubitemid 29240453)
8. Megarbane B, Borron SW, Trout H, et al. Treatment of acute methanol poisoning with fomepizole. Intensive Care Med 2001; 27: 1370-1378. (Pubitemid 32758936)
9. Kurcer Z, Oǧuz E, Iraz M, et al. Melatonin improves methanol intoxication-induced oxidative liver injury in rats. J Pineal Res 2007; 43: 42-49. (Pubitemid 47035220)
10. Poli G. Liver damage due to free radicals. Br Med Bull 1993; 49; 604-609.
11. Parthasarathy NJ, Kumar RS, Manikandan S, Narayanan GS, Kumar RV, and Devi RS. Effect of methanol-induced oxidative stress on the neuroimmune system of experimental rats. Chem Biol Interact 2006; 161: 14-25.
12. Pavlovic V, Pavlovic D, Kocic G, et al. Effect of monosodium glutamate on oxidative stress and apoptosis in rat thymus. Mol Cell Biochem 2007; 303: 161-166. (Pubitemid 47261313)
13. Tsakiris S, Karantana GA, Simintzi I, and Schulpis KH. The effect of aspartame metabolites on human erythrocyte membrane acetylcholinesterase activity. Pharmacol Res 2006; 53: 1-5. (Pubitemid 41619372)
14. Kadiiska MB and Mason RP. Acute methanol intoxication generates free radicals in rats: an ESR trapping investigation. Free Radic Biol Med 2000; 28: 1106-1114. (Pubitemid 30314709)
15. Lanping MA, Zaiqun LIU, Bo Z, Li Y, and Zhongli L. Inhibition of free radical induced oxidative hemolysis of red blood cells by green tea polyphenols. Chin Sci Bull 2000; 45: 2052-2056. (Pubitemid 32141919)
16. Butera D, Tesoriere L, Di Gaudio F, et al. Antioxidant activities of sicilian prickly pear (Opuntia ficus indica) fruit extracts and reducing properties of its betalains: betanin and indicaxanthin. J Agric Food Chem 2002; 50: 6895-6901. (Pubitemid 35253190)
17. Piga A. Cactus pear: a fruit of nutraceutical and functional importance.JProfAssocCactus 2004; 6: 9-22. (Pubitemid 40134324)
18. Stintzing FC, Schieber A, and Carle R. Phytochemical and nutritional significance of cactus pear. Eur Food Res Technol 2001; 212: 396-407. (Pubitemid 33808366)
19. Stintzing FC, Herbach KM, Mosshammer MR, et al. Color, betalain pattern, and antioxidant properties of cactus pear (Opuntia spp) clones. J Agric Food Chem 2005; 53: 442-451. (Pubitemid 40129939)
20. Jiang JQ, YC WC, and Lice YH. A new alkaloid from Opuntia vulgaris. Yao Xuc Bao 2003; 38: 677-679.
21. Kim JH, Park SM, Ha HJ, Moon CJ, Shin TK, and Kim JM. Opuntia ficus-indica attenuates neuronal injury in in vitro and in vivo models of cerebral ischemia. J Ethnopharmacol 2006; 104: 257-262.
22. Tesoriere L, Butera D, Pintaudi AM, Allegra M, and Livrea MA. Supplementation with cactus pear (Opuntia ficus-indica) fruit decreases oxidative stress in healthy humans: a comparative study with vitamin C. Am J Clin Nutr 2004; 80: 391-395. (Pubitemid 41080012)
23. Zou DM, Brewer M, García F, et al. Cactus pear: a natural product in cancer chemoprevention. Nutr J 2005; 4: 25-37.
24. Lowry OH, Rosebrough NJ, Farr AL, and Randall RJ. Protein measurement with Folin phenol reagent. J Biol Chem 1951; 193: 265-275.
25. Buege JA and Aust SD. Microsomal lipid peroxidation. Methods Enzymol 1972; 51: 302-310.
26. Beyer WF and Fridovich I. Assaying for superoxide dismutase activity: some large consequences of minor changes in conditions. Anal Biochem 1987; 161: 559-566. (Pubitemid 17046011)
27. Aebi H. Catalase. ed. H.U. Bergmeyer. In: Methods of Enzyme Analysis Vol. II Verlag Chemie, Weinheim, 673-684.
28. Flohe L and Gunzler WA. Analysis of glutathione peroxidase. Methods Enzymol 1984; 105: 114-121.
29. Gabe M. Techniques histologiques (Histological technics). Paris: Masson Publisher, 1968.
30. Kalender Y, Uzunhisarcikli M, Ogutcu A, Acikgoz F, and Kalender S. Effects of diazinon on pseudocholinesterase activity and haematological indices in rats: the protective role of Vitamin E. Environ Toxicol Pharmacol 2006; 22: 46-50.
31. Armutcu F, Coskun O, Gurel A, et al. Vitamin E protects against acetone-induced oxidative stress in rat red blood cells. Cell Biol Toxicol 2005; 21: 53-60. (Pubitemid 40767687)
32. Tesoriere L, Fazzari M, Allegra M, and Livrea MA. Biothiols, taurine, and lipidsoluble antioxidants in the edible pulp of Sicilian cactus cladodes pear (Opuntia ficus-indica) fruits and changes of bioactive juice components upon industrial processing. J Agric Food Chem 2005; 53: 7851-7855. (Pubitemid 41499630)
33. Zou DM, Brewer M, Garcia F, et al. Cactus cladodes pear-a natural product in cancer chemoprotection. Nutrition 2005; 4.
34. Gentile C, Tresoriere L, Allegra M, Livrea MA, and D'Alessio P. Antioxidant betalains from cactus cladodes pear (Opuntia ficus-indica) inhibit endothelial ICAM-1 expression. Ann N Y Acad Sci 2004; 1028: 481-486. (Pubitemid 40361850)
35. Lee JC, Kim HR, Kim J, and Jang YS. Antioxidant property of an ethanol extract of the stem of Opuntia ficus-indica var. Saboten. J Agric Food Chem 2002; 50: 6490-6496. (Pubitemid 35216759)
36. Atrens DM, van der Reest A, Balleine BW, Menendez J, and Siviy SM. Effects of ethanol and tertiary butanol on blood glucose levels and body temperature of rats. Alcohol 1989; 6: 183-187.
37. Wolfram RM, Kritz H, Efthimiou Y, Stomatopoulos J, and Sinzinger H. Effect of prickly pear (Opuntia robusta) on glucose and lipid-metabolism in nondiabetics with hyperlipidemia-a pilot study. Wien Klin Wochenschr 2002; 114: 840-846. (Pubitemid 35356122)
38. Fernandez ML, Lin EC, Trejo A, and McNamara DJ. Prickly pear (Opuntia sp.) pectin alters hepatic cholesterol metabolism without affecting cholesterol absorption in guinea pigs fed a hypercholesterolemic diet. J Nutr 1994; 124: 817-824. (Pubitemid 24200586)
39. Wills PJ and Asha VV. Protective effect of Lygodium flexuosum (L.) Sw. extract against carbon tetrachlorideinduced acute liver injury in rats. J Ethnopharmacol 2006; 107: 7-11.
40. Paula M, Mathangi DC, and Namasivayam A. Free radical changes in methanol toxicity Esther. Indian J Physiol Pharmacol 2003; 47: 207-211. (Pubitemid 36433250)
41. Dhabhar FS and McEwen BS. Acute stress enhances while chronic stress suppresses cell-mediated immunity in vivo: a potential role for leukocyte trafficking. Brain Behav Immun 1997; 11: 286-306. (Pubitemid 28108139)
42. Sivapiriya V and Venkatraman S. Effects of dimethoate (O,O-dimethyl S-methyl carbamoyl methyl phosphorodithioate) and ethanol in antioxidant status of liver and kidney of experimental mice. Pestic Biochem Physiol 2006; 85: 115-121.
43. Galati EM, Tripodo MM, Trovato A, Miceli N, and Monforte MT. Biological effect of Opuntia ficus indica (L.) Mill (Cactaceae) waste matter. Note I: diuretic activity. J Ethnopharmacol 2002; 79: 17-21. (Pubitemid 34017235)
44. Galati EM, Monforte MT, Tripodo MM, Aquino A, and Mondello MR. Antiulcer activity of Opuntia ficus-indica (L.) Mill. (Cactaceae): ultrastructural study. J Ethnopharmacol 2001; 76: 1-9. (Pubitemid 32510725)
45. Hernandez AF, Lopez O, Rodrigo L, et al. Changes in erythrocyte enzymes in humans long-term exposed to pesticides: influence of several markers of individual susceptibility. Toxicol Lett 2005; 159: 13-21. (Pubitemid 41317222)